The Best Colon Cleansers (2022) – Learn The Science

Here are the 2022's best colon cleansers with expert unbiased reviews. See our rankings of the most effective colon cleansing supplements available.

What is a Colon Cleanse?

A colon cleanse is a mechanical procedure that is supposed to flush out your gastrointestinal tract and improve GI problems like constipation or indigestion.

The Best Colon Cleansers (2022) – Learn The Science
A natural colon cleanse may be helpful for your digestive health. Shutterstock Images

Up to 70% of the immune system dwells in your digestive tract, which is why maintaining healthy digestion is a must. Digestion is defined as a process wherein the food is broken into a form that can be absorbed into the blood system and carried to cells to supply them with the nourishment they need to stay energetic and healthy.

It is also the process that flushes toxins away from the organism. Although digestion is something we tend to overlook, it’s impossible to deny the fact it plays a significant role in our wellbeing and weight loss as well.

If you want to lose weight, you have to make sure your digestion is healthy and regular.

One of the easiest ways to improve digestive health is by using top rated colon cleansers. They’re efficient, practical, and easy to find.

We reviewed the best colon cleansers in 2022 to make your choice for the ideal product easier.

Do You Need Colon Cleansing?

Your gut has the perfect balance of good and bad bacteria[1]. However, due to various factors including lifestyle habits, the ration between these bacteria can change.

Believe it or not; your body is “informing” you something’s wrong by sending some signs that you probably assign to stress or some other health-related problem.

Here are some telltale signs that are telling you it’s time for a colon cleanse:

  • Low energy/fatigue
  • Constipation
  • Brain fog, inability to focus, Feeling depressed
  • Overweight/difficulty to lose weight,
  • Trouble sleeping
  • Sexual dysfunction
  • Unexplained headaches
  • Unexplained stiffness/soreness
  • Skin problems

As you can see, what happens in your digestion tract has an immense influence on your entire body.

If you’re experiencing these problems, you should consider getting a colon cleanser.

Need Colon Cleansing

The Best Colon Cleansers for 2022

Check out the best options in 2022 to get the right fix by reading this guide.

1. Vital Reds

Vital Reds is a powerful red berry-flavored drink supplement packed with healthy polyphenol-enriched fruit that promotes overall wellness and immunity. The product provides you with additional energy, enhances the skin, supports the health of your heart, and includes probiotics which promote digestive health and wellness.

It can help promote regular bowel movements and ease symptoms like diarrhea and bloating. The manufacturer of Vital Reds is Gundry MD, a doctor-run health and wellness company that uses 100% pure organic ingredients.

They offer a 90-day money back warranty if you are not happy with the product in any way. This supplement is easy to take; just mix one scoop of the blend with 8 ounces of water and drink. The Vital Reds reviews were generally very positive, with many customers raving about its great benefits.

2. Colon Detox Plus

Colon Detox Plus is a diet supplement manufactured by Vita balance company. This product is an all-natural supplement produced to prevent toxins and to help support a sound digestive system.

The product capsules contain Aloe Vera and various ingredients, which are natural supplements capable of supporting the healthy functioning of the digestive system. It includes calcium as well as prebiotics flora to support and maintain healthy intestinal flora.

It contains natural, pure substances that can help with colon cleansing.

Colon Detox Plus is a one-of-a-kind colon cleansing product that claims to help detoxify the colon in just 15 days. As a result, it is recommended that you take two capsules daily, one for breakfast and one for dinner.

3. Morning Complete

Morning Complete by ActivatedYou promises to support overall bodily health, wellness, and strengthen the immune system. Flavored like apple and cinnamon, this formula balances your blood sugar, provides you with an abundance of extra energy, and supports liver and cellular functioning. In addition, it contains probiotics which support healthy digestion and ease symptoms like bloating, constipation, and gas.

The beauty of this product is in its enriching collection of ingredients, including a green superfoods blend packed with antioxidants. The company makes this product is a secure facility in the U.S and follows rigid safety standards. They also offer a generous 90-day return policy. It can replace your morning coffee and give you all the energy and well-being you need to get through the day.

4. Multi-GI 5

Multi-GI 5 is a potent organic drink supplement which contains 12 gut-elevating ingredients including fiber, probiotics, and prebiotics to promote digestive wellness. It promotes a healthy gut lining, balances the gut flora, and improves digestion and regularity. In addition, this drink can help with weight loss by controlling hunger and cravings.

Multi-GI 5 also provides users with a wealth of extra energy, which can help you to be more active and burn more calories. In the Multi-GI 5 reviews, customers have reported that along with digestive and weight-loss benefits, they have experienced a renewed feeling of optimal health and wellness.

The manufacturer is Unify Health Labs, a holistic health supplement company located in Woodland Hills, California. American musician Randy Jackson’s weight loss and gut health journey inspired the formation of this organization, which has an excellent reputation in the market.

5. Goli Apple Cider Vinegar Gummies

These delicious, apple-flavored gummies are a big hit in the market, with many of the Goli Apple Cider Vinegar Gummies reviews giving them a huge thumbs up. Ellen DeGeneres even discussed and highlighted this product on her show in the past. This is the perfect supplement for users who don’t like the idea of a drink.

Goli Apple Cider Vinegar Gummies provide numerous health benefits, including supporting healthy digestion, enhancing the skin, detoxing your body, providing you with energy and helping with weight loss.

This formula is suitable for vegans, gluten free, and produced in an FDA-approved facility under GMO safety standards. The manufacturer recommends that you take 1-2 gummies, 3 times a day, preferably with food. Goli Nutrition is a reputable company who donates some of their proceeds to child welfare causes.

6. Bio Complete 3

Bio Complete 3 is a total gut health supplement which includes prebiotics, probiotics, and postbiotics. This formula promotes balance in the gut for a healthy microbiome, and it promises to eliminate digestive symptoms like gas and bloating. In addition, it can eliminate cravings and curb your hunger, and help you lose some of that stubborn fat.

Bio Complete 3 also provides you with an abundance of extra energy, helping you to be more productive and more active. The manufacturer of this product is Gundry MD, a physician-run company which produces their formulas according to science and research. They are offering a 90-day money back guarantee, which gives you plenty of time to try out the product to see if it works for you.

7. Probiotic 40-Billion

Probiotic 40-Billion is a dietary supplement formulated to support digestion and improve the overall health of the digestive system. This product helps in preventing and healing inflammatory bowel conditions.

Also, this supplement is natural and improves the immune system through enhanced digestive function. The formula used provides good bacteria which aids in inhibiting the harmful bacteria that cause adverse effects on the internal systems like diarrhea. Using this supplement also helps in maintaining the internal flora healthy, thus supporting the health of the gut.

This supplement is available online and costs $34.95 per bottle. Each bottle contains 60 capsules. This supplement is suitable for women and men who are above 18 years and can be taken daily.

Probiotic 40-Billion’s powerful formula primarily utilizes four specific strains of good bacteria that are needed for a healthy, balanced intestinal flora. These four bacterium strains include Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus Plantarum, and Lactobacillus paracasei.

The fact that Probiotic 40-Billion only utilizes good bacterium strains means the product is considered safe, and no side-effects are expected to occur, even with the prolonged use of this supplement.

8. Zenith Detox

Zenith Detox is one of the natural formulas that contains a blend of clinically proven ingredients produced by Zenith Labs. The product is claimed to support body detoxification systems.

The Zenith Detox supplement consists of natural ingredients. It contains all the important nutrients and vitamins to keep an optimal level for liver function. This product helps to improve immune function and digestion.

There are claims that Zenith Detox is like a restart method that you simply do to your body once in a while, improving overall health and keeping the gut clean and healthy.

It is recommended to take just two capsules each morning, as this product contains a blend of 3 distinctive ingredients developed to support and improve the body’s natural detoxification system. Zenith Detox is also claimed to help by providing toned muscles, an excellent physique, and make you full of energy.

9. Probiotic T-50

This is another natural supplement that can make you understand the in and out of how your body works. The manufacturer of probiotics T-50 is known as Zenith Labs, a company with a positive reputation and an extensive list of applicable products on the market.

Probiotic T-50 supplement is said to have the capability to replace your metabolic process by melting inflexible abdominal fat and opening up nerve pathways for more outstanding communication between brain cells to sharpen your memory as quickly as possible. There are claims that the blend of nutritional probiotics can increase the elasticity and lifespan of skin cells in a few days and gives you a skin that seems to be younger and smoother.

The product is said to be loaded with natural ingredients that significantly improve a person’s health, alleviate digestive problems, belly fat, and mental slippage. It is recommended to take 1 Probiotic T-50 capsule once daily.

10. Colosan

Colosan is dubbed as the best way to start your pursuit for a healthier body and fitter lifestyle. It is formulated as the first step that every dieter should take on their journey towards optimal internal detox and toward better weight management. The manufacturer recommends using Colosan before trying out other types of colon cleansing.

This colon cleanser supplement is affordable and can be purchased at various online retailers. It has been formulated with natural ingredients, and the manufacturer claims that the user will not experience any side-effects while they are using the supplement. The product also claims to assist with improving the flow of waste; thus reducing the chance of experiencing constipation or other related digestive issues.

Colosan is available in both powder and tablet form, which makes this a very versatile product. Individuals can choose between buying a powder that they can mix with water or a beverage, or rather a capsule that they can take with a glass of water.

The powder form of Colosan comes in a 200-gram container and costs $22.95. The capsules come in a bottle with 120 capsules and will cost the customer a total of $19.95. It should be noted that combo packs are available that offers the products at lower prices.

11. Colon Clenz

Colon Clenz is an all-natural supplement that acts as a colon cleanser to assist with eliminating excess waste and toxins from the human body.

The product has been manufactured by a company known as Natural Balance and combines a variety of gentle and natural laxative ingredients that have been scientifically proven to help the digestive tract better eliminate waste without causing any significant side-effects. Colon Clenz is very affordable, especially when compared to some of the other options we have mentioned in our post.

Customers can purchase Natural Balance’s Colon Clenz for only $10 – this will provide the buyer with an entire month’s supply of the product. Colon Clenz can be used daily, but it should be noted that, since the product is a natural laxative, caution should be taken as dehydration may occur.

The primary ingredient utilized in Colon Clenz’s formula is Senna leaf extracts. In addition to Senna Leaves, this product also includes Slippery Elm, Black Walnut Hull, and Cascara Sagrada. In addition to acting as a gentle laxative, it should be noted that Colon Clenz may also help to improve the overall health and function of the digestive system, and may assist with conditions such as constipation and bloating.

12. Go Cleanse

The last product on our list of colon cleansers is Go Cleanse. This is yet another natural supplement that can be used to assist the function of the digestive tract, while also helping to detoxify the body of waste material and toxins.

The manufacturer of Go Cleanse is known as Green Organics, a company that has a positive reputation and quite an extensive list of useful products on the market.

The effectiveness of Go Cleanse is backed by numerous positive reviews, which can be found at various locations on the internet.

According to the manufacturer of this product, users will experience improvements in their bowel movements, relief of constipation, and they will experience a healthier-feeling in their gastrointestinal tract.

What makes this product particularly unique is the fact that, unlike the majority of colon cleansers out there, Go Cleanse has included a range of antioxidants in addition to the regular ingredients found in some other similar formulas.

Antioxidants are vital for the well-being of the human body, and the inclusion of these substances in this formula will provide the user with added benefits.

Acai is one of the primary ingredients found in Go Cleanse. In addition to Acai, other components have also been included, such as Cape Aloe leaf extracts, Cascara Sagrada, bentonite clay, black walnut powder, and senna leaf extracts.

Do Colon Cleansers Work?

Colon cleansing is the necessity to periodically clean the body in the bid to remove waste stuck on the colon walls, flush toxins, and establish the balance between good and bad bacteria.

When you use a colon cleanse, you’re detoxifying your entire body. These cleansers work by pushing toxins out of the organism to promote healthy well-being and weight loss.

More efficient digestion is a major benefit of colon cleansers; this way, your digestive tract absorbs nutrients from food at a faster rate.

Supplemental colon cleanses appear to be safer than mechanical colon irrigation.

A report by Dr. Ranit Mishouri and other medical doctors at the Georgetown University School of Medicine presented several cases of patients who had serious adverse health effects from mechanical colon cleansing.

Dr. Ruben Acosta and Dr. Brook Cash also caution against the use of mechanical colon cleansing in a 2009 review article in the American Journal of Gastroenterology. The benefits are minimal, and risks have been identified.

What Should You Take Into Consideration While Choosing Best Colon Cleansers?

The only way to get all these amazing benefits from a colon cleanser is to ensure you make an excellent choice. That can be quite tricky because there are numerous products of this type and all of them promise similar things – normal digestion, improved health, more energy, weight loss, and so on.

Naturally, not all products are created equal, and one has to be careful when purchasing.

Here is how to differentiate good products from bad ones:

  • Reliable manufacturer
  • Customer satisfaction is ensured by money back guarantee
  • All-natural list of ingredients
  • Other users had positive experiences with the product
  • Colon cleanser is safe to use without adverse effects

Recommended Dosage

The primary dosing concern in colon cleansing is the quantity of the laxative ingredients.

For senna-based colon cleanses, a typical dose is between 20 and 40 mg total per day.

Are there risks associated with natural colon cleansers?

When taking any type of supplement, the safety of the ingredients found in such a supplement should always be a top priority amongst the user.

There are thousands of different colon cleanser supplements on the market today, and knowing about the possible side-effects that may be caused by these supplements is vital.

It should be noted that the majority of these supplements are often considered safe, but prolonged use or the use of a supplement with certain ingredients, such as psyllium husk, can lead to the development of adverse reactions.

According to LiveStrong[2], the most concerning possible side-effects that may occur when a person takes colon cleansing supplements, especially over an extended period of time, includes an imbalance in electrolytes within their body, a low bacteria count in their gastrointestinal tract and the possibility of becoming dehydrated.

Best Colon Cleansers Review

We have reviewed the most popular colon cleansers present on the market today and got impressive results.

Our reviews aim to help you narrow down your selection and purchase the product that will, indeed, deliver what promised.

The Best Colon Cleansers

What else can you do to enhance colon health?

What you eat — not what you flush through your colon — may have the greatest impact on colon health, lowering your risk of colon cancer and enhancing your overall health.

Reminder: You don’t need to do colon cleanses every day or even every so often to be healthy, though they may have health benefits when done sporadically.

The typical American consumes about 15 grams a day, but you need closer to 25 grams to 30 grams. If there are no gluten issues, add sources of both insoluble fiber, such as cereal and whole grains, and soluble fiber, such as bran, some fruit, some vegetables, and oatmeal.

Also, drink plenty of fluids. Avoid tobacco and limit red meat. Regardless, talk to your doctor to ensure that you have the greatest experiences possible using them.


Colon cleansers pose as safe tools that help users safely perform body detox. With regular usage, cleansers improve digestive health, establish regularity, boost your energy levels, and help you lose weight.

Remember, it’s all about finding the perfect product using the simple buying advice listed above.

Don’t make any purchase before researching to find out more about the cleanser and the brand that created it.

Click on the links below every product to read their full reviews and identify the ideal product to help you become healthier and energetic.

Horne, S. Journal of Herbal Pharmacotherapy, 2006; vol. 6(2): pp. 93-100.
Baptist Health Systems: "Colon Cleansing: Don't Be Misled by the Claims."
U.S. National Library of Medicine: "Soluble vs. insoluble fiber.:

Ellen Ratliff, MS, RD, Pn1

Ellen is passionate about helping people become the healthiest version of themselves and using nutrition to heal from disease and thriv

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

Disclosure of Material connection: Some of the links in the post above are "associate sales links."This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."