In This Review
Overview of Tru Niagen
As we age, our bodies naturally face a multitude of challenges. Decreased energy levels, cognitive decline, and weakened immune systems are common issues that can significantly impact our quality of life.
These problems not only burden the individual but also place a significant strain on caregivers who are responsible for their well-being. The emotional and physical toll on both parties can be overwhelming.
In such scenarios, supplements can be of great help. In this review, we are going to explore Tru Niagen, its working mechanism and how it can help.
What is Tru Niagen?
Tru Niagen is a health supplement that contains a special form of vitamin B3 called nicotinamide riboside (NR). As we get older, our bodies produce less of a substance called NAD+, which is important for keeping our cells healthy and functioning well. NAD+ helps our cells produce energy and carry out many important processes.
By taking Tru Niagen, you can help increase NAD levels in your body. This can improve how your cells work, support a healthy metabolism, and contribute to your overall well-being. In simpler terms, Tru Niagen helps your body stay energetic and healthy as you age by ensuring your cells have the fuel they need to keep running smoothly.
How Does Tru Niagen Rate According to Our Experts?

Brand Highlights
- ChromaDex, Inc. is a company led by a group of experts who specialize in uncovering the potential of NAD for improving the way people age.
- Their board is composed of nutritional experts, Nobel Prize winners in chemistry, and doctors specializing in Alzheimer’s research.
- For now, nonetheless, it seems like Tru Niagen is their only featured product.
Key Ingredients
- Nicotinamide Riboside Chloride
- Microcrystalline cellulos
- Hypromellose
Pros
- Scientifically Researched
- Patented Ingredient
- Different Dosage Options
Cons
- Long-Term Effects Are Unclear
- The efficacy of the formula requires more research
- May take quite a long time to work and become effective
- Expensive Compared to Alternatives
- It has ingredients that may potentially trigger allergic reactions
- Not FDA Approved for Any Medical Use
About the Brand
Tru Niagen is manufactured by ChromaDex, a U.S.-based company specializing in NAD+ research and supplementation. The company positions itself as a leader in the healthy aging industry, claiming to have developed one of the most researched NAD+ boosters available. With endorsements from well-known scientists, ChromaDex presents its supplement as a scientifically-backed product.
However, like many supplement companies, its claims are not regulated by the FDA, and its efficacy relies heavily on self-funded research. While it does hold patents on Niagen®, alternative NAD+ boosters with similar mechanisms exist at a lower price.
Some users also report feeling no tangible benefits, raising concerns about whether the product justifies its premium cost.
How Does Tru Niagen Work?
Tru Niagen is a supplement, which means it raises the level of a vital molecule, NAD+, in your cells. NAD+ is necessary for generating energy, fixing damaged DNA, and keeping your cells healthy. Since NAD+ production naturally declines as people age, and so do the energy and functioning of the body cells.
Tru Niagen capsule form of supplement delivers a special form of vitamin B3 called nicotinamide riboside that is converted into NAD+ when consumed. It increases NAD+ production allows your cells to generate more energy and speed up the repair process.
An increase in NAD+ causes your cells to create more ATP, which is the primary fuel for cells, which is why you get more energy. Increasing NAD+ production boosts the activity of enzymes that repair damaged clusters of DNA.
This is crucial for preventing diseases and slowing the ageing process. NAD+ boosts the activity of mitochondria, or the cell’s powerhouses, which helps to reduce harmful oxidizing stress and ensures proper cell function.
However, the effectiveness of this process varies from person to person. Some researchers question whether NAD booster healthy aging supplements actually increase NAD levels in a meaningful way, or if the body regulates them back to baseline. Moreover, boosting NAD+ doesn’t necessarily guarantee improved health, as factors like diet, sleep, and overall lifestyle play a much bigger role in long-term well-being.
Tru Niagen Ingredients – Are they Safe and Effective?
This supplement uses high-quality ingredients to ensure the effectiveness of its product. Here are some of the ingredients found in the formula:

Tru Niagen Supplement Fact
Nicotinamide Riboside Chloride
– This compound is another form of niacin or vitamin B3, and it exists in many anti-aging supplements. Once it enters the body, it is converted into NAD+, a coenzyme responsible for numerous biological processes.
Nicotinamide riboside (NR) is pivotal in replenishing cellular NAD+ levels, which diminish with age, thereby contributing to various health issues such as mitochondrial dysfunction and cellular senescence. NR supplementation offers promise in mitigating these declines and promoting overall health and longevity by boosting NAD+ levels.
Learn more about the chemistry and important functions of this compound via article from the Encyclopedia of Biological Chemistry[1].
Microcrystalline cellulos
– This non-digestible substance comes from wood pulp. It’s included in many foods and supplements, serving functions such as anti-caking, preserving, bulking, texturizing, etc.
A study on PubMed found that MCC can help your stomach work better and lower lipids in your body. It also affects how enzymes in your body process fats[2].
Hypromellose
In Tru Niagen, Hypromellose helps your body absorb NR. It’s a plant-based alternative to gelatin, making the supplement safer. According to Mayo Clinic, Hypromellose also helps with dry eyes, protects your eyes from harm in some cases, and makes hard contact lenses and fake eyes more comfortable. It’s even used in some eye exams[3].
How to Use Tru Niagen?
The recommended dosage for Tru Niagen varies depending on the product:
Standard dose: 300mg per day (one capsule).
High-strength version: 1000mg per day for those seeking maximum NAD+ support.
Immune formula: 150mg per day, combined with immune-supporting ingredients.
For best results, it should be taken at the same time every day, preferably with food to reduce the risk of nausea or stomach discomfort. The company suggests consistency for at least 8 weeks before expecting noticeable benefits. However, since individual results may vary, some users report seeing no significant changes even after prolonged use.
Benefits of Tru Niagen
Supports Cellular Energy Production and Metabolism : This benefit helps your body produce the energy it needs at the cellular level. It enhances the efficiency of metabolic processes, ensuring your cells have the fuel they need to function optimally.
Promotes Healthy Aging and Longevity: By promoting healthy ageing, this benefit helps slow down the ageing process and contributes to a longer, healthier life. It supports the maintenance of cellular functions and reduces the risk of age-related diseases.
Enhances Cellular Repair and Resilience Against Stressors: This benefit focuses on improving the body’s ability to repair damaged cells and build resistance against environmental stressors. It helps keep your cells robust and better equipped to handle physical and emotional stress.
Improves Overall Health and Well-being: By supporting various bodily functions, this benefit leads to an enhancement in overall health and well-being. It contributes to a stronger immune system, better mental health, and a higher quality of life.
Side Effects of Tru Niagen
- Generally well-tolerated, but some individuals may experience mild side effects like nausea, upset stomach, or diarrhea.
- Concerns exist about potential risks for individuals with cancer, as NAD+ may exacerbate tumor growth in certain cases.
- It is advisable to consult a healthcare professional before starting Tru Niagen, especially for individuals with existing medical conditions or those taking other medications.
Safety of Tru Niagen
Tru Niagen is generally considered safe for most adults when taken as directed. Clinical studies have not reported serious side effects, but some users experience:
Long-term safety is still being studied, and individuals with underlying health conditions should consult a doctor before use. Since NAD+ metabolism is complex, taking high doses without medical guidance might not be beneficial.
Tru Niagen | Does It work? (Video Credit: Poolarity – Life Hacks YouTube Channel)
Tru Niagen Review – FAQs
Q: Where Can I Buy Tru Niagen?
A: You can purchase this supplement on Amazon and Walmart, both of which offer convenient shipping options and competitive pricing.
Q: Who should use Tru Niagen?
A: Individuals looking to support cellular energy and aging-related health concerns may consider using Tru Niagen.
Q: Can Tru Niagen help with aging and energy levels?
A: Yes, Tru Niagen is designed to promote healthy aging and support energy levels by boosting NAD+ production.
Q: Is Tru Niagen Safe to Take?
A: Tru Niagen can be okay to take, but it’s important to talk to a doctor first. They can help decide if it’s safe for you based on your health and any other medicines you’re taking.
Q: How Should Tru Niagen Be Used?
A: The recommended serving size for Tru Niagen is 300 mg, or one capsule every day. The manufacturer does not specify an optimal time to take the supplement.
Q: What Does Tru Niagen Do for the Body?
A: Tru Niagen supports cellular health by increasing NAD+ levels, which are crucial for energy production and maintaining mitochondrial function. It helps combat age-related decline and promotes overall vitality.
Q: Is Tru Niagen Safe to Take?
A: Tru Niagen can be okay to take, but it’s important to talk to a doctor first. They can help decide if it’s safe for you based on your health and any other medicines you’re taking.
Q: How Long Does Tru Niagen Take to Work?
A: Tru Niagen 300 mg may begin to demonstrate its effects after eight weeks of consistent intake, with some individuals experiencing an increase in NAD levels by 40-50%. However, individual responses may vary, and it’s advisable to continue using Tru Niagen 300 mg as directed to potentially observe its full benefits over time.
Q: What Are the Side Effects of Tru Niagen?
A: The manufacturer claims that Tru Niagen is free of any major side effects. However, like most health supplements, it still has the potential to cause minor side effects such as nausea, indigestion, headaches, dizziness, or diarrhea.
Q: What are the precautions to follow while using this product?
A: Precautions to follow while using this product include avoiding it if you have allergies to Tru Niagen’s, nicotinamide riboside, or hypromellose. Pregnant and lactating women, as well as individuals taking medication, should consult a physician before consuming the supplement. Additionally, this product is intended for adults above the age of 18.
Q: What Is Tru Niagen’s Return Policy?
A: Tru Niagen offers a 30-day money back guarantee, but only for items returned in the original packaging. The company does not give refunds for partially-used products.
Tru Niagen Customer Reviews
Tru Niagen, a supplement containing nicotinamide riboside (NR), has garnered mixed reviews from users. While some report experiencing benefits, such as increased energy levels or improved overall well-being, others have not noticed any significant difference after taking it. Here’s a breakdown of what people are saying:
A reviewer on Amazon shared their experience with Tru Niagen:
I have to say I was skeptical, but after the first day of taking two, I have noticed my energy level up. I definitely needed this for my days off I’d recommend purchasing and give it a try. ~ Cindy Mcconnell
“Overhyped and overpriced” – “I took this daily for three months and felt absolutely no difference. Maybe it works for some people, but I regret spending so much money on something with no noticeable effects.”~ Daniel K.
“Disappointed after all the hype” – I really wanted this to work. The marketing made it sound amazing, but after two bottles, I feel the same. No changes in energy or sleep. A waste of money for me.”~ Richard P.
Another users of Tru Niagen from Amazon expresses:
Causes loose stools I took the product (2 capsules) for 2 weeks and noticed a difference in my energy level. My joints also do not feel as sore as before. However, it causes me to have loose stools. ~ Alice Tan
I didn’t notice any appreciable difference of any kind after taking this for one month daily. I couldn’t find any change in how I feel, sleep, etc. It just didn’t do anything for me.
Tru Niagen Review – Final Verdict
Tru Niagen is a supplement meant to help your body’s cells stay healthy, made by experts. It’s supposed to keep you feeling good and maybe even help you look younger if you’re still young.
But, not everyone who tries Tru Niagen feels the same way about it. Some people say it works for them, while others don’t notice much difference. Like most supplements, you have to use Tru Niagen regularly and be patient to see if it helps you.
The product is expensive, its long-term benefits remain uncertain, and its effectiveness varies greatly among users. Additionally, cheaper NAD+ alternatives exist, often with similar formulations. If you’re considering NAD+ supplementation, exploring more affordable options with comparable research might be a smarter choice. There are lots of other health products out there, like Gundry MDH2 Restore, claiming to do similar things. In the end, whether Tru Niagen is right for you depends on how your body reacts to it. It’s a good idea to talk to a doctor before you start taking it.
The most effective health supplements that are currently present on the market can be found below. We have taken our time and rated these products in accordance to these five essential factors: quality of active ingredients, energy boosting, hormone balance restoration, cognitive function improvement and immune system strengthening.
Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned health supplements and probiotic supplements based on the available research:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.
6 Customer Reviews for Tru Niagen

Customer Reviews & Ratings
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Tru Niagen Ques and Ans
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Q: Does Tru Niagen help with nitric oxide if have clogged arteries?
A: Tru Niagen, a supplement containing nicotinamide riboside, may help support heart health and mitochondrial function, but it does not directly increase nitric oxide levels or help with clogged arteries.
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We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.
[3] Hypromellose (Ophthalmic Route) : https://www.mayoclinic.org/drugs-supplements/hypromellose-ophthalmic-route/description/drg-20064245#
**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.
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Jennifer Lawson
Alice Ramos
Joy L OSTROWSKI
Steve Zimmie
I recently read that it could be beneficial to increase the dose. So I started taking 600mg per day (300 in the morning, 300 in the afternoon). I have more energy throughout the day, and I’m able to get my weight under control more easily.
Scott
Smith J.