Pure Encapsulation’s NeuroPure Reviews – Does It Work and Is It Safe?

NeuroPure is a multivitamin supplement made of vegan ingredients containing neurotransmitter precursors that support emotional wellness and emotional stability.

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In This Review

What is Pure Encapsulation’s NeuroPure?

NeuroPure is a multivitamin supplement that supports neurocognitive, emotional, and behavioral health. The supplement helps to replenish vital nutrients that synthesize neurotransmitters.

The supplement is made of vegan ingredients scientifically proven to support neuronal health. Emotional health relies on the availability of cofactors and nutrient blocks.

For this reason, NeuroPure contains Metafolin L-5- MTHF cofactor, vitamins, and minerals such as zinc. In addition, it is supposedly gluten-free, hypoallergic, and non-GMO.

How Does Pure Encapsulation’s NeuroPure Rate?

Overall Rating: 3
Pure Encapsulation’s NeuroPurePure Encapsulation’s NeuroPure


Value for Cost

2/5Value for Cost
Return Policy

0/5Return Policy


Brand Highlights

  • Contains vegetarian ingredients scientifically proven to improve neuronal health
  • Gluten free, Hypoallergenic and Non-GMO
  • Entailed in the PureSYNAPSETM product line
  • Manufactured in an FDA-Certified and NSF-GMP-approved facility
  • Recommended by healthcare professionals



*All individuals are unique. Your results can and will vary.

Key Ingredients

  • Vitamin B6
  • Folate
  • Zinc
  • Quercetin
  • 5-Hydroxytryptophan


  • Contains no artificial colors, sweeteners, or flavors
  • Claims to support mood and emotional stability
  • Contains cofactors and nutrient building blocks that synthesize neurotransmitters
  • Free from wheat, eggs, soy, and dairy ingredients that cause allergic reactions


  • Contains very high amounts of DL-Phenylalanine that might be dangerous
  • Cannot be purchased without a recommendation from a healthcare professional
  • Expensive
  • No Refund Policy

About the Brand

The supplement is a product of Pure Encapsulations LLC. It is part of the PureSYNAPSETM developed by James Greenblatt, an integrative psychiatrist. The company manufactures high-quality premium supplements that provide integrative support for mood, memory, sleep quality, stress, and healthy diets.

The supplements are developed with medical expertise in an NSF-GMP-approved facility. Pure Encapsulations supplements are free from allergens, unnecessary additives, and preservatives. The supplements are developed to facilitate the achievement of your wellness goals.

How Does It Work?

NeuroPure contains neurotransmitter precursors such as DL-phenylalanine that enhance the production of dopamine and serotonin, which support emotional wellness. Serotonin relieves symptoms of anxiety, sleep, and mood disorders.

Studies show that zinc contained in the supplement enhances positive mood and reduces depression and anger-hostility. DL-phenylalanine encourages PEA activity that supports emotional and mood stability. The ingredient urges the brain to generate more neurotransmitters, such as dopamine[1].

Its ingredients may help improve neuropathy-related symptoms by enhancing the function of proteins. Proteins play a crucial role in the sensory system. Curcumin in the supplement maintains cytokine balance and enhances serotonin function.

Pure Encapsulation’s NeuroPure Ingredients – Are they Safe & Effective?


It is also regarded as Vitamin B9, essential for basic cell function in the human body. Folate helps in the formation of DNA and RNA, which dictate the function of the cells, as elaborated in our review of the Total Brain Boost supplement.

Folate is considered crucial during fetal development, brain, and spinal cord maturation. Studies show that folate supplementation in pregnant women reduces congenital disabilities. It also plays an important role in the nervous system[2].


Quercetin is mostly found in citrus fruits, berries, green tea, apple, and parsley. It possesses various biological features, including anti-inflammatory, antioxidant, and anti-fibrotic. Quercetin contains flavonoids that help prevent brain disorders[3].

Quercetin is used in supplements because of its therapeutic importance in preventing neuronal cell death and memory loss. It is also used as a medication for neurodegenerative diseases.


DL-Phenylalanine is a combined form of L-phenylalanine found in proteins and D-phenylalanine manufactured in the lab. L-phenylalanine enhances the production of thyroid hormones that support cognitive and physical health.

Phenylalanine is a precursor for the production of dopamine. Dopamine helps to improve concentration. The Journal of Neural Transmission shows that DL-Phenylalanine relieves symptoms of depression and agitation[4].

Zinc Picolinate

Zinc supports the growth of the immune and central nervous systems. It is required in the formation of enzymes, proteins, hormones, and growth factors that take part in neurodevelopment.

Studies show that zinc is needed in the secretion of enzymes like DNA polymerase which is key in brain development. Zinc is important for neural tube formation and stem cell proliferation[5].

In our comprehensive article on Claritox Pro Reviews, we thoroughly documented the presence of Zinc ingredient and provided detailed insights and analysis.

Vitamin B6

Vitamin B6 is not produced by the body but can be acquired from supplements. Vitamin B6 enhances the creation of neurotransmitters such as serotonin that regulate emotions as we referenced in our review of Cogniflex. It also decreases levels of amino acid homocysteine linked to depression[6].


5-HTP is derived from the amino acid tryptophan and serves as a precursor to serotonin, a crucial neurotransmitter in the brain. It plays a significant role in mood regulation, sleep, and appetite. Our Nuzena 5-HTP Pure + Review suggests that 5-HTP supplementation may improve mood disorders like depression and anxiety, enhance sleep quality, and aid in weight loss by increasing serotonin levels. Elevated serotonin levels contribute to feelings of fullness and reduced appetite.


Claritox Pro

*All individuals are unique. Your results can and will vary.

Frequently Asked Questions

Q: Does Pure Encapsulation’s NeuroPure Really Work?

A: The supplement contains neurotransmitter precursors that promote the production of dopamine and serotine, which facilitate mood stability and emotional balance.

Q: How Should You Take Pure Encapsulation’s NeuroPure?

A: Customers are recommended to take 2 capsules, regularly 1-2 times a day. The dosage is to be taken in between meals.

Q: Who Should Buy Pure Encapsulation’s NeuroPure?

A: The supplement is suited for adult individuals who desire improved emotional balance and mood stability. NeuroPure is medically approved to provide integrative and individualized neuronal health support.

Q: Does NeuroPure Cause Side Effects?

A: There are no reported side effects with the supplement intake.

Q: What is Pure Encapsulation’s NeuroPure Return Policy?

A: It is difficult to assure customers that the product comes with a return guarantee since it is not stated on the product’s official website. Some websites, however, claim that the product has a 15% refund policy.

Q: Where to Buy NeuroPure and How Much is It?

A: NeuroPure is readily available on the product’s official website. The supplement goes for a retail price of $60.65. Although healthcare practitioners recommend it, it is quite expensive compared to other neuronal health supplements.

Q: What Sets Pure Encapsulation’s NeuroPure from the Competition?

A: NeuroPure is an exceptional supplement as it contains high-quality vegan ingredients that have been scientifically proven. The formula is free from artificial colors, flavors, soy, dairy, magnesium stearate, and preservatives; hence suitable and safe for all customers.

Pure Encapsulation’s NeuroPure Reviews from Customers

Best Multivitamin

I love the NeuroPure supplement because it does not contain any calcium or iron in most supplements. The supplement has enhanced my energy levels and mood. It contains just the right ingredients that support emotional wellness. I have not experienced any side effects with the product. Great Product.
– Scarlett

Terrible odor

The doctor recommended the supplement because of its excellent ingredients. Taking the supplement is a challenge due to its bad smell and taste. I cannot take the supplement after meals to avoid the terrible taste in my mouth. I purchased the product but only used it for 10 days. Despite the medical recommendation, I couldn’t withstand the smell.
– Alice

Good product

I have been taking the supplement for around a year. I have bipolar disorder, which causes extreme emotional feelings. The supplement has helped me gain more control of my mood swings. The product is quite effective.
– Justin

Excessive selenium levels

I got sick and visited a clinic where my blood tests were sampled. The doctor was concerned about high levels of selenium in my blood. The high levels were contributing to the gastrointestinal problems I was experiencing. The supplement works great, but it is advisable to get checked if you experience any symptoms.
– Regan

Generally good

The supplement is pretty good. I can say it has enhanced my emotional stability. It seems to miss out on some essential minerals. I love the product, apart from the smell, which makes me feel sick.
– Brad.



*All individuals are unique. Your results can and will vary.


NeuroPure is a high-quality and clinically multivitamin proven to support emotional wellness. The supplement promises to enhance overall neurotransmitter function. Customers are assured of the product’s safety as it is free from unnecessary preservatives, colors, and ingredients.

Customers require a recommendation from a healthcare practitioner to purchase the product directly from the product’s website, which is quite unfortunate. Customers also have to research to get clarity on the refund policy. The supplement is also available on other websites but at a different price from the official website.

NeuroPure contains vegan ingredients that have been scientifically and carefully selected to provide mood and emotional balance. Despite its high price, the supplement is worth purchasing as it is very effective and ranked as the most recommended supplement brand by healthcare professionals.

Like NeuroPure, the natural brain supplement NeuroQ may help to relax and calm the mind with regular use. However, determining the efficacy of NeuroPure is difficult due to the absence of information regarding the dosages of its ingredients.”

More than ever people of all ages are struggling with memory problems. People are unable to disconnect from their work, while students are under immense pressure to perform. Brains are overloaded with information that must be remembered. A quality memory enhancement product might contain clinically proven ingredients that will help to enhance not only memory, but also focus and night concentration. Memory products might help to optimize overall mental health and brain function.

Below you'll find some of the most effective memory products on the market today, in our opinion.

Our Top Memory Supplements

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned brain health supplements and nootropic based on the available research:

Cogniultra | Maximum Strength Cognitive Formula
Improves Cognitive Function*Gold Star Evidence
Enhances Memory and Attention*Gold Star Evidence
Reduces Brain Fog*Gold Star Evidence
Sharpen Memory Alertness*Strong Evidence
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Overall Rating: 4.9
Noocube | Premium Brain Productivity Supplement
Strengthen Memory*Gold Star Evidence
Boost Memory & Mental Alertness*Gold Star Evidence
Improve Concentration*Gold Star Evidence
Improve Focus & Mood*Strong Evidence
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Overall Rating: 4.8
Nootrogen | Nutritional Nootropic Brain Support
Supports Memory*Gold Star Evidence
Supports Cognition*Strong Evidence
Improve Focus*Gold Star Evidence
Supports Stress*Strong Evidence
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Overall Rating: 4.8
Claritox Pro | Vertigo Support Supplement
Boosts Brain Function*Gold Star Evidence
Strengthens Focus and Clarity*Gold Star Evidence
Improves Cognitive Health*Strong Evidence
Reduces Stress and Anxiety*Strong Evidence
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Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.7

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for NeuroPure

Pure Encapsulation’s NeuroPure Reviews – Does It Work and Is It Safe?

Customer Reviews & Ratings

2.0 out of 5

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  1. Joseph Gleaton

    I have used it for months with no relief. BUYER be ware.
    This product is a piece of CRAP; does not live up to its HYPE. I have used it for months with absolutely no RELIEF. BUYER BEWARE. A waste of your money! Save your money. This is like throwing your hard-earned money down the drain. In my opinion, this is a scam; a scam.
  2. Paul

    Effective but so pricey....
    I was prompted to order the NeuroPure by my husband. He underwent carpal tunnel surgery once and suffered from nerve damage. His surgeon was preparing to perform the surgery once more. My spouse made the decision to first test the NeoroPure to see whether it could be of assistance. With his surgical results, he has opted against having any additional procedures. But because the item is so pricey, not everyone can afford it.

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Pure Encapsulations LLC.
120 Capsules
Vitamin B6, Folate, Zinc, Quercetin, and 5-Hydroxytryptophan.

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    6 Sources

    We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

    [1] Effect of zinc supplementation on mood states in young women: a pilot study https://pubmed.ncbi.nlm.nih.gov/20087376/
    [3] Role of Quercetin Benefits in Neurodegeneration https://www.researchgate.net/publication/308384352_Role_of_Quercetin_Benefits_in_Neurodegeneration
    [4] Dl-phenylalanine in depressed patients: an open study https://pubmed.ncbi.nlm.nih.gov/335027/
    [5] Zinc in the central nervous system: From molecules to behavior https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757551/#:~:text=Zinc%20is%20essential%20for%20normal,proliferation%20and%20differentiation%20during%20neurodevelopment.
    [6] The homocysteine hypothesis of depression https://pubmed.ncbi.nlm.nih.gov/17541043/

    **This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

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