Nuzena 5-HTP Pure + Review: Is This A Good Nootropic Supplement?

Nuzena 5-HTP+ is a natural support for anxiety, sleep, weight loss, & mood enhancement. Our review explores cognitive insights with scientifically backed ingredients.

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In This Review

Overview Of Nuzena 5-HTP Pure +

Many internal and external factors affect our mental health daily. From work stress and pressure from school to family obligations and poor sleep, all these things affect how we think and view the world.

Our brains need good chemical and hormonal balance to sustain mental health. Thankfully, scientists and researchers know enough about brain chemistry now to identify what can help.

5-HTP Pure + is a supplement that uses the amino acid 5-hydroxytryptophan to promote cognitive health. 5-HTP Pure + is a natural supplement that can have a beneficial impact on both mental and physical health.

In the following 5-HTP Pure + review, we will be taking a deep dive into this product including its formula, how people have reacted to it, and what you can expect from it. Read on to learn everything you need to know about 5-HTP Pure +.

What is 5-HTP Pure +?

First and foremost, 5-HTP Pure + is a natural and safe supplement. It is readily available over the counter because it does not contain any harsh chemical compounds or stimulants that can be habit-forming.

The sole active ingredient in the 5-HTP Pure + formula is the naturally occurring amino acid known as 5-hydroxytryptophan. This amino acid acts as a precursor to the neurotransmitter serotonin, which plays many very important roles in cognitive performance and health.

As a result, 5-HTP Pure + is a powerful nootropic that can help with things like sleep quality, mood balancing, positive outlook, decreased stress, and even weight loss. 5-HTP Pure + is also a gluten-free supplement and non-GMO so it should be safe for most adult users.

How Does 5-HTP Pure + Rate?

Overall Rating: 4.8
5-HTP Pure +Nuzena 5-HTP Pure +


Value for Cost

4.8/5Value for Cost
Return Policy

4.7/5Return Policy


Brand Highlights

  • Focused on science-backed formulas.
  • The company offers free health consultations and reports for customers.
  • Nuzena’s research staff consists of registered dietitians, food scientists, and healthcare professionals.
  • The company emphasizes integrative approaches to health and wellness.
  • Nuzena focuses on transparency and unrivaled quality.
  • They have strict internal quality standards.

Key Ingredients

  • 5-Hydroxytryptophan


  • It can help fend off depressive thoughts.
  • It can improve your circadian rhythms.
  • 5-HTP Pure + can also support healthy weight loss.
  • The formula for 5-HTP Pure + is hormone-free.
  • There is no sugar in the 5-HTP Pure + formula.
  • It works to increase serotonin levels.


  • The capsules contain gelatin so they may not be suitable for vegetarians.
  • The product may sell out quickly since it is so popular.

You can BUY it directly from the Official Website

How Does 5-HTP Pure + Work?

It’s important to note that there is only one active ingredient in the 5-HTP Pure + formula. But this doesn’t make it any less effective. It makes it safer for more adult users because, with just one active ingredient, the likelihood of an allergic reaction is remote.

5-HTP Pure + works to improve your overall mood by increasing levels of the neurotransmitter serotonin in the brain. The Cleveland Clinic[1] eloquently describes the role and the importance of serotonin to our overall health in the following quote:

“Serotonin is a chemical that carries messages between nerve cells in the brain and throughout your body. Serotonin plays a key role in such body functions as mood, sleep, digestion, nausea, wound healing, bone health, blood clotting, and sexual desire. Serotonin levels that are too low or too high can cause physical and psychological health problems.”

As we can see in the above quote, serotonin is a neurotransmitter that affects virtually every aspect of our health. 5-HTP Pure + by Nuzena works to increase serotonin levels by supplementing 5-hydroxytryptophan which converts to serotonin in the brain[2].

As a result, this supplement can help improve your sleep quality which will help you wake up feeling more rested and more ready to take on the day – most likely making you a more productive person.

5-hydroxytryptophan, the main ingredient in this supplement, is also often used to treat depression. So it’s certainly possible that taking this supplement will help you fend off depressive thoughts and feelings[3].

5-HTP Pure + Ingredients – Are They Safe & Effective?

5-HTP Pure + Supplement Facts

5-HTP Pure + Supplement Facts

As mentioned earlier, there is only one active ingredient in the formula for 5-HTP Pure +.

So we took a deep dive into it and reviewed the scientific data on it. Take a look at what we found.


5-hydroxytryptophan is an amino acid that is crucial for the production of serotonin in the body.

The primary role of 5-HTP in commercial supplements is to make serotonin more bioavailable in the body by helping it cross the blood-brain barrier.

Because of this effect, 5-HTP has been extensively studied for its effect on depression. In one study cited by the Mount Sinai[4] staff, we read that:

Preliminary studies indicate that 5-HTP may work as well as certain antidepressant drugs to treat people with mild-to-moderate depression. Like the class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs), which includes fluoxetine (Prozac) and sertraline (Zoloft), 5-HTP increases the levels of serotonin in the brain.

And while 5-HTP was observed to act much like the mentioned prescription anti-depressants, it is natural and therefore doesn’t cause the same adverse side effects. So it is a safer way to battle depression.

But 5-HTP has other exciting benefits. For instance, it can help you lose weight. In another report from the Mount Sinai staff, it was reported that:

A follow-up study, which compared 5-HTP to placebo during a diet and non-diet period, found that those who took 5-HTP lost about 2% of body weight during the non-diet period and another 3% when they dieted. Those taking placebo did not lose any weight.

The mechanism seemed to stem from lesser caloric intake in the 5-HTP group. The 5-HTP group didn’t eat as much as normal since the amino acid promoted feelings of satiation after a meal.

Benefits, & Safety of Nuzena 5-HTP Pure +

Benefits of 5-HTP Pure +

Mental and Emotional Health: The supplement is beneficial for mental and emotional health due to its role in increasing serotonin levels, which can improve mood and reduce symptoms of depression and anxiety.

Sleep Regulation: It helps regulate sleep by increasing serotonin, which can then be converted into melatonin, aiding in better sleep quality.

Weight Management: By potentially suppressing appetite, 5-HTP may assist in weight management, making it easier to control cravings and reduce overeating.

Bone Health Benefits: Calcium Carbonate is crucial for maintaining strong bones and teeth, preventing bone density loss, and reducing the risk of fractures.

Cardiovascular and Muscle Function: Calcium is vital for heart and muscle function, ensuring effective muscle contraction and nerve transmission.

Safety Measures of 5-HTP Pure +

Consultation with Healthcare Providers: Essential for individuals on medication, especially those affecting serotonin levels or with a history of kidney issues.

Start with Lower Doses: Particularly for 5-HTP, starting with a lower dose can help minimize side effects.

Hydration: Adequate fluid intake is important, especially when taking Calcium Carbonate, to help prevent kidney stones

Possible Side Effects of 5-HTP Pure +:

Gastrointestinal Issues: Both supplements can cause digestive discomfort. 5-HTP may lead to nausea, diarrhea, and stomach pain, while Calcium Carbonate can cause constipation and bloating.

Mood and Sleep Alterations: 5-HTP might cause mood swings, drowsiness, or over-sedation due to its impact on serotonin levels.
Serotonin Syndrome Risk: When 5-HTP is combined with other serotonin-increasing substances, there’s a risk of serotonin syndrome, a potentially serious condition.

Kidney Health Concerns: High doses of Calcium Carbonate may increase the risk of kidney stones and, in excessive amounts, lead to hypercalcemia, with symptoms like nausea and confusion.

You can BUY it directly from the Official Website

Nuzena 5-HTP Pure + Review – FAQs

Q: Who should take 5-HTP Pure +?

A: 5-HTP Pure + is suitable for both men and women. It is intended for adults only.

Q: Are there any side effects of 5-HTP Pure +?

A: No major side effects have been reported by people who have taken 5-HTP Pure + but you should still ask a doctor before taking it.

Q: How much does 5-HTP Pure + cost?

A: Each bottle of 5-HTP Pure + costs $40.

Q: Are there any discounts or deals?

A: Yes. When you enroll in the auto-ship program you get 15% off the price of a bottle which gets lowered to $34.

Q: How many capsules are in each bottle?

A: Each bottle of 5-HTP Pure + contains 60 capsules which is the equivalent of a month’s supply.

Q: How should you take 5-HTP Pure +?

A: The instructions state that users should take 2 capsules a day. Take one in the middle of the day and one in the evening for the best results. You can also ask your doctor how you should be taking 5-HTP Pure +.

Q: When can I expect to see results from 5-HTP Pure +?

A: Some users may feel the benefits almost immediately while it may take months for others.

Q: Does 5-HTP Pure + reduce feelings of anxiety?

A: Yes. The formula for 5-HTP Pure + was designed to increase relaxation and reduce stress.

What Do the 5-HTP Pure + Reviews Say?

Confirmed customers have responded very positively to 5-HTP Pure +. Some of the 5-HTP Pure + reviews mention:

I’ve been using 5-HTP Pure + for a few weeks now, and I’m incredibly pleased with the results. My mood has noticeably lifted, and I find myself more relaxed and less anxious during the day. What’s even more impressive is the positive impact on my sleep quality. I’m falling asleep faster and waking up feeling more rested. Highly recommend this product if you feel like you’ve been in a bit of a rut since COVID. I find this has helped me just feel like me again. –Laura Planch

After trying various supplements to improve my sleep, I finally found success with 5-HTP Pure +. The difference is remarkable – falling asleep faster, staying asleep throughout the night, and waking up feeling refreshed. I appreciate the purity of the ingredients and the absence of any grogginess in the morning. It’s become a staple in my nightly routine, and I highly recommend it to anyone struggling with sleep issues. – Carl S.

Lovely experience from the quiz, to the friendly staff, to quick shipping, and one month in I am liking the product. –June Cornell

Nuzena 5-HTP Pure + Review – Conclusion

5-HTP Pure + is a supplement that can benefit your health in many ways. It can improve your cognitive health by reducing feelings of anxiety and making it easier to maintain a bright outlook.

It could benefit your sleep health by increasing serotonin which helps regulate sleep cycles. It can even help you lose some weight by increasing feelings of satiation after a meal and reducing occurrences of overeating.

What’s more, the positive impact of 5-HTP Pure + is not merely a claim – it’s substantiated by numerous glowing reviews attesting to its efficacy. With its safe and natural approach to enhancing cognitive health, we highly recommend giving it a try. Elevate your well-being and embrace the positive changes that 5-HTP Pure + can bring to your life.

There have been many positive reviews in response to 5-HTP Pure + as well. It’s a safe, natural way to improve cognitive health

Where To Find It?

To learn more, check it out on the official Nuzena website!

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for 5-HTP Pure +

Nuzena 5-HTP Pure + Review: Is This A Good Nootropic Supplement?

Customer Reviews & Ratings

4.5 out of 5

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  1. Jason

    Helpful Aid with No Side Effects!
    Dealing with anxiety has always been a challenge, but 5-HTP Pure + has provided a natural and effective solution. I feel calmer and more in control of my emotions. It’s a relief to find a supplement that promotes mental well-being without any side effects.

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    4 Sources

    We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

    [1] Serotonin:
    [2] 5-HTP:
    [3] 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology:
    [4] 5-Hydroxytryptophan (5-HTP):

    **This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

    *Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

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