Wellsprings Serenity Natural Progesterone Cream Reviews: Is the Product Worth the Price?

A natural, bioidentical progesterone cream used for relief of menopause symptoms and other conditions related to hormone imbalance.

In This Review

What is Wellsprings Serenity Natural Progesterone Cream?

Wellsprings Serenity Natural Progesterone Cream is a bioidentical progesterone cream used by women to alleviate the uncomfortable symptoms of menopause.

Marketed as an alternative to Hormone Replacement Therapy, the active ingredient in this cream is natural progesterone, a hormone that declines after age 40.

Low progesterone symptoms include irritability, fatigue, irregular or frequent menstruation, low sex drive, hot flashes, insomnia, weight gain, and mood swings.

Each 2.1 oz jar of Serenity contains 1,260 mg of bioidentical USP Pharmaceutical grade Natural Progesterone extracted from plant saponins.

Wellsprings Serenity Natural Progesterone
Wellsprings Serenity Natural Progesterone – Natural Menopause Relief

Who is the Manufacturer of Wellsprings Serenity Natural Progesterone Cream?

Wellsprings Serenity Natural Progesterone Cream is manufactured by Wellsprings.

According to the company, this menopause product has been chosen by both doctors and women for over 20 years as the best alternative to HRT.

Its official manufacturer’s website has a clearly outlined ingredient list, clear instructions on the dosage and how to use it as well as an FAQ page and user testimonials.

Users of Serenity allegedly report experiencing relief in their menopause symptoms and an improvement in their quality of life without any side effects.

How Does Wellsprings Serenity Natural Progesterone Cream Work?

In contrast with taking a progesterone supplement, Wellsprings Serenity Natural Progesterone Cream contains an advanced liposomal formula that allows for 97-100 percent progesterone absorption by the skin.

The cream should be applied each morning and evening to the fatty tissue areas of the body, including the thighs, hips, buttocks, upper arms, and lower abdomen.


*All individuals are unique. Your results can and will vary.

The cream should be massaged into a different body part each time it is applied.

The manufacturer recommends using a double dosage –1/4 teaspoon instead of 1/8 teaspoon) during the first month of application.

Each 1/8 teaspoon contains 15 mg of natural progesterone.

According to the manufacturer, a healthy woman will naturally produce 20-25 mg of progesterone during the second half of her monthly menstrual cycle, so this cream attempts to mimic the body’s natural production of progesterone.

Wellsprings Serenity Natural Progesterone Cream Ingredients – Are they Safe & Effective?

Per every 60gm jar of this cream, their is:

Bio-Identical Usp Pharmaceutical Grade Natural Progesterone.

This has been extracted from plant saponins and helps combat symptoms of low progesterone like low sex drive, irritability, hot flashes, mood swings, weight gain, insomnia and fatigue.

Grapefruit Seed Extract

Relieves hot flashes experienced at menopause. According to the study, it is also effective in improving the physical and psychological symptoms of the menopause.

Other ingredients in the formula include;

Deionized Water, Caprylic/Capric Triglyceride, Glycerin, Aloe Barbadensis, Leaf Juice, Progesterone, Phenoxyethanol, Sodium PCA, Methyl Glucose Sesquistearate, Aminomethyl Propanol, Carbomer, Tocopheryl Acetate, Caprylyl Glycol, Sorbic Acid, Cetyl Alcohol, Glyceryl Stearate, Isopropyl Myristate, Stearic Acid, Sodium, Hyaluronate, PEG-20 Methyl Glucose Sesquistearate, and Xanthan Gum.

What are the Advantages of Wellsprings Serenity Natural Progesterone Cream?

  • Manufacturer’s website includes a comprehensive list of ingredients, as well as clear instructions on how to use this product, user testimonials, and a FAQ page
  • This cream is fragrance free, not tested on animals, and free from common allergens
  • Natural progesterone has been prescribed since the 1930s to treat menopause related symptoms
  • There have been no reported side effects associated with natural progesterone
  • In contrast with taking progesterone orally, over 90 percent of the hormone is absorbed by the body during transdermal application

What are the Disadvantages of Wellsprings Serenity Natural Progesterone Cream?

  • Wellsprings no longer offers Serenity in the United States
  • Some users have criticized this cream for containing progesterone without oestrogen

The Dos and Don’ts while Using Wellsprings Serenity Natural Progesterone Cream

A double dosage of this cream should be taken during the first month of application. Consumers should finish the full jar of cream to allow hormone levels to stabilize.

If symptoms are severe, women can use a quarter-teaspoon each morning and evening, but dosage should be modified by each woman.


*All individuals are unique. Your results can and will vary.

Wellsprings Serenity Natural Progesterone Cream Questions and Answers

Q: How Much Does Wellsprings Serenity Natural Progesterone Cream Cost?

A: The cost of Wellsprings Serenity Natural Progesterone Cream is £26.99.

Q: Is the serenity cream vegan?

A: The Serenity Smoothing Cream is vegan, gluten free, non-GMO and cruelty free.

Q: Where you can buy Wellsprings Serenity Natural Progesterone Cream?

A: You can buy the product from its official website and online retailers.

Q: Where is wellspring located, what country, state or city

A: Postal Address:

Eros House
Grand Rue, St Martins
Guernsey, GY4 6LQ
United Kingdom

Q: What are the similar products to Wellsprings Serenity Natural Progesterone Cream?

A: The similar products include Amberen, Estrovera, and Serenol.

Wellsprings Serenity Natural Progesterone Cream Review – Final Verdict

Wellsprings’ website offers a wealth of information on their natural progesterone cream, including a detailed list of ingredients and user testimonials.

Although it does not offer deals when more than one jar of cream is ordered, the manufacturer accepts PayPal as a billing option and the natural menopause supplement is shipped the same or next working day.

Wellsprings Serenity Natural Progesterone Cream is no longer offered in the United States.

Fortunately, natural therapies for menopausal symptoms such as weight gain, hot flashes, night sweats, decreased libido, and mood swings are available. Since many women experience weight gain during menopause, many natural menopause supplements contain herbs and botanicals that support a healthy metabolism. Menopause supplements should be evaluated on proven ingredients, ability to reduce hot flashes and night sweats, ability to provide hormonal balance and boost libido and its overall value.

Below you’ll find some of the most effective menopause supplements on the market today, in our opinion.

Our Top Menopause Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned menopause supplements and vitamins based on the available research:

Amberen | Best Multi-Symptom Menopause Relief Supplement
Reduces Hot Flashes*Gold Star Evidence
Helps Restore Hormonal Balance*Gold Star Evidence
Better Sleep*Strong Evidence
Mood Improvement*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Estroven Complete Multi-Symptom Menopause Relief
Reduces Menopause Symptoms*Gold Star Evidence
Reduces Night Sweats*Gold Star Evidence
Improve Energy*Strong Evidence
Support Mood Swings*Moderate Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Metagenics Estrovera | Plant-Derived Menopausal Hot Flash Relief
Assists With Hot Flashes*Gold Star Evidence
Improve Mood Swings*Moderate Evidence
Ease Menopause Symptoms*Strong Evidence
Reduces Night Sweats*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Wellsprings Serenity Natural Progesterone Cream

Wellsprings Serenity Natural Progesterone Cream Reviews: Is the Product Worth the Price?

Average Customer Rating

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  1. lynda

    twenty-1 creme VS capsule
    I love the Twenty – 1 creme and it works wonders for me however I was thinking to switch to capsules. But would like to see some reviews on that particularly. And if I was to switch could I just go straight into taking the capsule once I’m done with the cream.
  2. Anna Bel

    Wonder cream
    I have used Wellsprings Serenity cream for a year now and can report an amazing difference to my health and wellbeing.

    I suffered terribly with night sweats and insomnia for years. At 51 I had my last period and it all went downhill from there.

    I developed vulval skin problems. Itching and sweating like never before. I couldn’t sleep for more than 2 hours at a time, however tired I became. My hair started to fall out and my overall skin condition was excessive dryness and flaking.

    In desperation, I trawled the internet for months. Researching everything, and finally came up with the choice to try Wellsprings Serenity cream.

    Wow! within a few months, people were complimenting me on how well I was looking, even to the degree of one person asking, Have you had work done with a wink in her eye. My mood was so much better, I started to feel energised and my skin complaints were gone. It did take a few months, but the difference in me is amazing! I have energy, my sleep has improved and is of better quality. My hair has stopped falling out and my skin is glowing. I cannot say that it will work for you as it has me, but what I can say, is 100% give it a go. I would not be without this cream now. I did not change any other part of my lifestyle while trying the cream. My supplements were as they had always been, this way I could give it an honest chance.

    My daughter had 10 years of IVF which left her bloated, lardy and irritable and with terrible skin and horrendous headaches. She was told she had estrogen dominance from all the medication given to her during the IVF episodes… She tried the cream too, but with a break for her period, and has never looked back. her gynecologist has been blown away by the change in my daughter’s mood and appearance.

    Two generations of a woman taking Wellsprings and transformed must count for something.

    If you are otherwise healthy, but suffering from the symptoms that progesterone cream may be able to help you with. Give it a go. If you want one make that we would recommend, then Wellsprings Serenity is the one to try.

    For people worrying about getting the correct measure…We went on eBay and purchased a set of cooks measuring spoons that had a 1/8th measure in the set.

    Hope that helps anyone out there, pondering on what to do.

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Wellsprings Serenity Natural Progesterone Cream
Wellsprings Serenity Natural Progesterone Cream Reviews: Is the Product Worth the Price?

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

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