In This Review
Overview Of Neprinol
Are you also feeling the aging effects on your body? Do you sometimes feel uneasy, tired, or feel heavy? After a certain age, this is obvious. As we grow older, our natural enzyme production decreases. This led to a wide range of health concerns. Therefore, we need a powerful combination of enzymes and nutrients that can help us get back our vitality and well-being.
That’s where Neprinol comes in – a unique supplement designed to support your body’s essential needs. The manufacturer claims it is packed with a potent blend of systemic enzymes and essential nutrients. It has also been claimed that Neprinol works directly with your body to help restore the enzyme levels that naturally decline with age, giving you the support you need to feel energized, comfortable, and vital once again.
TL;DR
- By age 40+, the body’s natural enzyme production begins to decline, which may affect digestion, circulation, and overall energy levels.
- Neprinol is a systemic enzyme supplement with proteolytic and fibrinolytic enzymes designed to support circulation, joint comfort, and immune health.
- Some users report better mobility and improved comfort over time, though results vary based on health condition and consistent use.
In this blog, we’ll explore the supplement Neprinol, we’ll understand the science behind this innovative supplement, find the roles of different enzymes and how they can benefit your body.
What is Neprinol?
Neprinol is a systemic enzyme supplement made by Arthur Andrew Medical. It comes in capsule form and is designed to support circulatory health, joint comfort, and immune function.
The supplement combines a blend of proteolytic and fibrinolytic enzymes as its primary active ingredients. It is marketed toward adults who want to maintain healthy blood viscosity, support the body’s natural inflammatory response, and promote tissue repair.
Neprinol is available in three sizes: 90, 150, and 300 capsules. It is taken on an empty stomach with water, and dosage varies from 2 to 9 capsules daily depending on the level of support needed.
How Does Neprinol Rate?
Neprinol
Brand Highlights
- Neprinol is manufactured by Arthur Andrew Medical.
- The company focuses on enzyme and probiotic-based dietary supplements.
- The manufacturer claims all the products are made in the USA.
- The formula is claimed to be formulated scientifically.
- Trusted by thousands of customers and recommended by physicians.
Key Ingredients
- Magnesium
- Proprietary Blend Neprinol AFD
- Systemic and Lipollytic Enzyme blend: Serrapeptase, Nattokinase, Lipase
- Neprinol Protease Blend
- Neprinol Enzyme and Cofactor Blend
Pros
- The product may lessen aches and pains
- Papain may promote healing and inflammation from overexertion.
- Promotes a healthy cardiovascular system and immune system.
Cons
- This product may seem expensive compared to other joint products.
- Enzyme potency and absorption can vary
- Results can take one to three months, which some may find slow.
- Not suitable for those on blood thinners or who are pregnant or nursing.
- No third-party testing mentioned.
About The Brand
Arthur Andrew Medical is a dietary supplement manufacturing company based in the United States and was started in 2003 to make Nepranol. The brand, which is based in the United States, since the last 20 years mosty manufactures enzyme and probiotic-based supplements.
Arthur Andrew Medical is not a typical supplement company, they claim they are reactive and focused on product development, as each supplement is formulated to provide a broad spectrum of benefits, as opposed to trending in the market.
How Does Neprinol Work?
Neprinol contains a blend of systemic, vegan-friendly enzymes, which work towards breaking down debris in the blood like excess fibrin and other unwanted proteins.
The ingredients serve to support normal inflammatory levels and are similar to other digestive enzymes. But, these specific ingredients target the bloodstream, not the gastrointestinal tract.
A study showed that orally given systemic enzymes have the potential to regulate inflammatory pathways and immunogenic functions[1].
The cleansing of the blood is claimed to support healthy cardiovascular and liver function, while also maintaining a healthy inflammatory response for everyday activity.
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Neprinol Ingredients – Are they Safe & Effective?
Neprinol Supplement Facts
Neprinol is a dairy, gluten, and soy-free product, as stated by the manufacturer. The following are the ingredients that constitute this product:
Magnesium
– Magnesium is known to strengthen the bones and improve cartilage consistency.
A study published in PubMed suggests that lower magnesium intake was linked to increased pain and decreased functionality in knee osteoarthritis, especially in those with limited fiber intake[2].
Proprietary Blend Neprinol AFD
– This proprietary blend is designed to safeguard joints against fibrin-related damage. It comprises various enzymes and compounds specifically tailored to promote joint health and support inflammation management.
Systemic and Lipollytic Enzyme blend: Serrapeptase, Nattokinase, Lipase
– A natural enzyme compound that assists in certain biochemical reactions related to the joints.
Additionally, research published in the journal Medicine indicates that systemic enzyme supplementation reduces cough and breathlessness, while also decreasing supplemental oxygen requirements in patients with pulmonary fibrosis[3].
Neprinol Protease Blend
– Protease is derived from Serratia, B. subtilis and A. oryzae – Another compound that is lauded for its ability to fight inflammation.
The journal Arthritis Research & Therapy discusses the role of proteases in maintaining the balance of cartilage and bone in a healthy state, highlighting their significant involvement in conditions such as RA, OA, and spondyloarthritis[4].
Neprinol Enzyme and Cofactor Blend
– Amla, Papain, Bromelain, Rutin, Coenzyme Q10 – This compound has a direct effect on blood vessels which can reduce the appearance and cause of spider veins and bruising.
How To Use Neprinol?
Neprinol is to be taken on an empty stomach along with 8 ounces of water, or as prescribed by your health care provider. When used as a maintenance aid, the dosage would be two to three capsules daily. The people who need more assistance can use four to six capsules per day, and the high dosage is nine capsules a day.
When taking larger doses every day, the doses can be broken into two or three portions per day to be better tolerated. Do not use this product without the approval of your doctor in case you are already on anti-coagulants or you are pregnant or lactating.
Benefits of Neprinol
- Better Digestion: Neprinol can help your body break down the food you eat more effectively, making it easier for your body to absorb the nutrients from that food.
- Improved Circulation: The ingredients in Neprinol can help keep your blood flowing smoothly throughout your body, preventing it from becoming too thick or sluggish.
- Reduced Discomfort: If you experience occasional aches or discomfort in your joints, especially after physical activity, Neprinol may help reduce that discomfort and support quicker recovery.
Side Effects of Neprinol
- Digestive Issues: Neprinol may lead to bloating, gas, or diarrhea, particularly when consumed on an empty stomach or in high doses.
- Allergic Reactions: With enzymes derived from plants and microbes, some individuals may experience allergic reactions, manifesting as rash, itching, or difficulty breathing.
- Interactions with Medications: Components in Neprinol, can interact with certain medications, potentially impacting their effectiveness or leading to side effects.
- Stomach Irritation: The enzymes present in Neprinol might cause stomach upset or irritation, especially when taken without food or in larger doses.
Safety of Neprinol
Nepranol is claimed to be prepared using vegan-friendly and non-genetic systemic enzymes and is accredited by the American Vegetarian Association, indicating a great interest in quality and purity of ingredients. Arthur Andrew Medical is the company through which it is produced in the USA under very high industry standards.
Nonetheless, those who are already under anti-coagulant drugs, pregnant, and lactating should not take Neprinol without the consent of the physician. Just like any dietary supplement, it is best that the consumer consults a qualified healthcare provider prior to its use especially those with underlying health conditions.
Neprinol Price
Neprinol is available in three size options, so you can choose what works best for your needs and budget.
- 90 capsules – $55
- 150 capsules – $85
- 300 capsules – $145
Neprinol Review – FAQs
Q: What Is Neprinol Good For?
A: Neprinol is beneficial for promoting cardiovascular health and supporting the body’s natural inflammation response due to its enzyme blend, aiding in overall wellness and vitality.
Q: How Should You take Neprinol?
A: Neprinol recommended dosage is two to three capsules per day for maintenance, four to six capsules for increased support, and nine capsules per day for therapeutic purposes. The capsules should be taken with eight ounces of water on an empty stomach.
It is recommended that the capsules be taken at least one hour prior to eating or two hours after a meal.
Q: How Much Does Neprinol Cost?
A: There are three options in which to purchase Neprinol: 90 capsules for $55.00, 150 capsules for $85.00, or 300 capsules for $145.00. The manufacturer offers free shipping within the United States.
Q: Does Neprinol Lower Cholesterol?
A: Neprinol is mainly utilized as a systemic enzyme supplement and might aid in promoting healthy circulation, yet its specific effect on cholesterol reduction remains unclear. Seeking advice from a healthcare provider is recommended for tailored recommendations regarding cholesterol management.
Q: What Are the Ingredients in Neprinol?
A: Neprinol contains a blend of systemic enzymes, including serrapeptase, nattokinase, bromelain, papain, and other proteolytic enzymes, as well as coenzymes and cofactors such as magnesium and Amla.
Q: Where is this product sold online?
A: You can buy it from Amazon or Walmart. Prices may vary, so check both sites before purchasing.
Q: Are there any alternatives to Neprinol?
A: Yes, there are multiple supplements on the market such as Purity H.A. Joint Formula, Lunaflex PM and Inflama-Care.
Q: What is Neprinol’s Return Policy?
A: Unopened items purchased directly from the manufacturer can be returned or exchanged within 30 days of the purchase date for a full refund or exchange.
What Do the Neprinol Reviews Say?
Customer opinions on Neprinol AFD are mixed. While some users report modest improvements, a notable portion feel the product does not justify its cost or deliver consistent results.
Several customers did not notice any benefits and found it too expensive. Others felt the formula was underpowered.
One reviewer noted that for serious fibrin control, the individual ingredients in full-strength form can be 10 to 15 times stronger than what this formula offers.
A Walmart reviewer simply stated,
“Have not felt any different than before I started to take it.” Others flagged the price as a concern, calling it “a bit pricey, honestly.” Overall, results appear inconsistent across users.
Neprinol Review – Final Verdict
Neprinol offers a blend of systemic enzymes to support healthy levels of fibrin and other debris in the blood. This is claimed to cleanse the blood to support cardiovascular and liver functions, as well as joint function.
The use of this product for some consumers may be limited as there is no certainty that pregnant or nursing women may use the product safely. There is also a warning for individuals who are taking anti-coagulants and it is recommended that they do not take this product without consulting their physician.
There may be similar joint relief products out there for these individuals who are looking for a product to assist with blood cleansing and joint, circulation, and immune system support.
Healthy joints allow us to move with ease. Joint damage can cause pain preventing you from doing the things you once loved. From aging to untreated sports injuries – many conditions lead to joint pain. A quality joint product may help reduce inflammation, repair existing tissue damage, and promote stronger joints, lessening susceptibility to future degeneration.
Below you'll find some of the most effective joint pain supplements on the market today, in our opinion.
Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned joint pain supplements based on the available research:








Callahan Vire
Gretchen Fletcher
I thought maybe it had just cleared up on its own, so I didn’t reorder Neprinol when I finished the bottle. Then a week or so later, the pain came back. I ordered a second bottle and lo and behold! The pain went away and is completely gone. I will never be without this amazing miracle product, even though I don’t really understand how or why it works.
Lydia