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Arthrozene Review 2025: Shocking Results or Hype? Find Out!

Is Arthrozene the answer to joint pain and stiffness? Learn how this supplement promises to improve flexibility and mobility in just 5 days! Here’s what you need to know before trying it.

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In This Review

Overview

If you find it hard to move without pain, experience joint discomfort after a long day, or constantly battle aching knees that slow you down, you’re not alone. Over 54.4 million Americans constantly battle with joint pain.

Many people facing the same struggles turn to joint supplements, hoping to find relief. Some of these supplements claim to ease discomfort, improve flexibility, and support long-term joint health. But with so many joint health supplements, it’s hard to tell which ones work.

One supplement that has gained attention is Arthrozene. People say it reduces stiffness, supports cartilage health and improves mobility. But does it work as they say? Or is it just another supplement with big promises?

This review will examine Arthrozene’s ingredients, possible drawbacks, and real customer experiences. By the end, you’ll know if it’s worth considering for joint health.

What Is Arthrozene?

Arthrozene is a joint health supplement in capsule form designed to help reduce stiffness, improve mobility, and support cartilage health. It combines three key ingredients ApresFlex® Boswellia Serrata Extract, Mobilee® Natural Chicken Comb Extract, and Collavant n2® Native Collagen Type II—which are said to target inflammation, lubricate the joint, and protect the cartilage.

Unlike some joint supplements that focus only on pain relief, Arthrozene addresses the root of joint discomfort by slowing cartilage breakdown and improving flexibility. The brand behind the product (Fisico Inc) also boasts that Arthrozene delivers results in as few as five days. This distinguishes it from many other joint health supplements.

Arthrozene is a natural alternative for people struggling with joint issues, whether due to aging, injury, or an active lifestyle. However, with its premium pricing, some may wonder if the benefits are worth the cost. Let’s find out.

How Does Arthrozene Rate?

Overall Rating: 3.8
ArthrozeneArthrozene

ingredient

3.9/5Ingredients

Value for Cost

3.7/5Value for Cost

return-policy

3.8/5Return policy

safety

3.7/5Safety

Brand Highlights

  • Manufactured by Fisico Inc., a health supplement company
  • Made in a GMP-certified facility
  • Uses patented ingredients from trusted suppliers
  • Non-GMO and free from artificial additives
  • Sold exclusively through the official Arthrozene website
  • It comes with a 365-day money-back guarantee
  • Uses third-party tested ingredients for quality assurance
  • Packaged in a 30-capsule bottle for a one-month supply

Key Ingredients

  • ApresFlex® (Boswellia Serrata Extract)
  • Mobilee® (Natural Chicken Comb Extract)
  • Collavant n2® (Native Type II Collagen)
  • Hyaluronic Acid
  • Boswellia Serrata Extract
  • Type II Collagen

Pros

  • Uses clinically studied ingredients from reputable sources
  • Made with patented formulations for potential effectiveness
  • Simple once-daily capsule for convenience
  • No unnecessary fillers or artificial additives
  • Manufactured by an established health supplement company

Cons

  • Higher price compared to other joint supplements
  • Only available through the official website

About the Manufacturer

Fisico Inc., a U.S.-based company, makes Arthrozene and other health supplements. The brand focuses on joint health, weight management, and general wellness.

Fisico states that its products follow strict quality standards in a GMP-certified facility. The company sources patented ingredients from third-party suppliers, including ApresFlex® Boswellia Serrata Extract, Mobilee® Natural Chicken Comb Extract, and Collavant n2® Native Collagen Type II.

Arthrozene is available only on the official website, allowing Fisico to oversee quality and distribution. The company provides a 365-day money-back guarantee, though research and third-party testing details remain limited.

How Does Arthrozene Work?

Arthrozene is formulated with a clinically-backed triple-action formula designed to address joint discomfort at its root. This powerful blend works synergistically to reduce inflammation, support cartilage health, and enhance joint lubrication—all essential for improving mobility and long-term joint comfort.

The formula includes ApresFlex®, a Boswellia serrata extract believed to lower inflammation by inhibiting 5-lipoxygenase (5-LO), an enzyme linked to joint discomfort. This may help ease stiffness and promote mobility.

Another key component, Mobilee®, provides hyaluronic acid, which contributes to joint lubrication. Research suggests oral hyaluronic acid supplementation can improve joint function and reduce pain, particularly in knee osteoarthritis.

Lastly, Collavant n2® contains type II collagen, a key protein in cartilage. This ingredient helps maintain cartilage integrity and reduces wear over time.

This triple-action formula doesn’t just mask symptoms; it works at a cellular level to promote better joint health, flexibility, and comfort. That’s what sets Arthrozene apart as a long-term solution for people looking to stay active without being held back by joint issues.

Arthrozene Key Ingredients – Are they Safe & Effective?

ApresFlex® (Boswellia Serrata Extract)

ApresFlex® is a patented extract derived from the Boswellia serrata tree, which is traditionally used for its anti-inflammatory properties. It is included in Arthrozene to help reduce joint inflammation and discomfort.

Clinical studies in the Journal of American Nutrition Association have demonstrated its efficacy; for instance, a randomized, double-blind, placebo-controlled trial found that 100 mg of ApresFlex® daily significantly improved joint comfort and function within five days.

Mobilee® (Natural Chicken Comb Extract)

Mobilee® is a natural extract rich in hyaluronic acid, collagen, and polysaccharides. It is added to Arthrozene to enhance joint lubrication and support overall joint function. Mobilee® can increase the body’s hyaluronic acid production tenfold, improving joint mobility and reducing pain.

Collavant n2® (Native Type II Collagen)

Collavant n2®/B-2Cool® provides native type II collagen, a primary protein in cartilage. Arthrozene aims to support cartilage structure and reduce joint pain. Studies published in The Eurasian Journal of Medicine suggest that supplementation with native type II collagen can improve joint function and alleviate discomfort in individuals with osteoarthritis.

Hyaluronic Acid

Hyaluronic acid, as documented in our Beverly Hills MD Multi Hyaluronic Acid Plumping Booster Review (another supplement containing this ingredient), is a naturally occurring substance in the body’s connective tissues, known for its ability to retain moisture. Arthrozene is included to improve joint lubrication, ease movement, and reduce stiffness.

Research published in the Nutrition Journal has shown that oral hyaluronic acid supplementation can enhance joint function and reduce pain in individuals with osteoarthritis.

Boswellia Serrata Extract

This extract, derived from the resin of the Boswellia serrata tree, has traditionally been used for its anti-inflammatory effects. In Arthrozene, it reduces inflammation and joint pain.

A study in the Journal of BMC Complementary Medicine and Therapies reported that Boswellia extract significantly alleviates pain and improves physical function in osteoarthritis patients.

Type II Collagen

Type II collagen is the main structural protein in cartilage, providing it with strength and elasticity. Arthrozene aims to support cartilage health and reduce joint discomfort. Research in Nutrients indicates that supplementation with type II collagen can significantly improve joint pain and function among osteoarthritis sufferers.

How to Use Arthrozene?

Follow these steps for the best results:

  • Take one capsule per day with a glass of water.
  • Consume on an empty stomach for better absorption.
  • Stick to a consistent schedule, taking it at the same time each day.
  • Avoid taking more than the recommended dose.

Benefits of Arthrozene

  • Supports Joint Comfort— Arthrozene includes Boswellia serrata extract, which may help reduce inflammation and ease discomfort, making movement more manageable.
  • Enhances Mobility and Flexibility— This formula, which contains hyaluronic acid and type II collagen, aims to improve joint lubrication, allow smoother movement, and improve flexibility.
  • Promotes Cartilage Health – The type II collagen in Arthrozene may help maintain cartilage structure and potentially reduce wear and tear over time.
  • May Provide Fast-Acting Relief – Customers say they see noticeable improvements within five days, quicker than many joint supplements on the market.

Arthrozene Side Effects : Is Arthrozene Safe?

Arthrozene Supplement Facts
Arthrozene Supplement Facts

Arthrozene is generally well-tolerated, with no serious side effects reported. However, some users may experience mild digestive discomfort, including nausea, bloating, or stomach upset. These effects are temporary and usually resolve on their own.

Boswellia serrata extract may cause minor gastrointestinal issues in some individuals, while collagen supplements have been linked to mild headaches or dizziness in rare cases.

To minimize potential side effects, take Arthrozene on an empty stomach as directed and stay hydrated throughout the day. If discomfort persists, consider adjusting the timing or consulting a healthcare professional before continuing use.

Safety

Arthrozene is made in a GMP-certified facility, ensuring quality and safety standards. The ingredients are sourced from reputable suppliers, and the formula uses clinically studied components, including ApresFlex® and Mobilee®, which have shown potential benefits for joint health.

While the natural formulation generally makes Arthrozene safe for long-term use, it’s crucial to consult a healthcare professional before starting extended use. This is especially important for individuals with medical conditions, pregnant or nursing women, and those on medication.

Most users tolerate it well, but mild digestive discomfort may occur. Following the recommended one-capsule-per-day dosage helps reduce the risk of side effects.

In summary, while Arthrozene is designed with safety and efficacy in mind, professional guidance ensures that long-term use aligns with your personal health needs.

How Effective Is Arthrozene?

Arthrozene is a doctor-formulated joint support supplement designed to address joint discomfort through a unique Triple-Action Formula. This formula targets inflammation, cartilage degradation, and joint lubrication to promote overall joint health.

ApresFlex® Boswellia serrata extract reduces inflammation, while Mobilee® Hyaluronic Acid helps lubricate joints for smoother movement. Collavant n2® Native Type II Collagen supports cartilage integrity, making it a well-rounded solution for joint health.

Many users report noticeable relief within just a few days of use, experiencing significant improvements in flexibility and reduced joint stiffness. Arthrozene’s fast-acting Triple Action Formula sets it apart from other joint supplements, delivering quick and lasting results, so you can get back to your active lifestyle sooner.

With its scientifically supported ingredients and premium formulation, Arthrozene delivers on its promises, offering a natural and effective way to support joint health. For those who look to stay active and comfortable, this supplement provides a trusted solution backed by both science and customer satisfaction.

Arthrozene Frequently Asked Questions

Q: How long does it take to see results with Arthrozene?

A: Many users notice improvements within five days, but results vary. For best outcomes, consistent use for a few weeks is recommended.

Q: Can Arthrozene be taken with other supplements or medications?

A: Arthrozene is generally safe, but interactions may occur. If you take medications or other supplements, consult a healthcare provider before use. It’s particularly important to do so if you’re on any blood-thinning drugs or have underlying health conditions. These situations can increase the chances of interactions, making professional guidance essential.

Additionally, individuals with blood pressure conditions should exercise caution and potentially avoid taking Arthrozene. Always seek advice from a licensed healthcare professional or pharmacist to ensure safe usage and to address any specific health concerns you may have.

Q: Does Arthrozene have any side effects?

A: Most users tolerate it well, but mild stomach discomfort, nausea, or headaches may occur. These effects are usually temporary and resolve on their own.

Q: Is Arthrozene FDA-approved?

A: Dietary supplements do not require FDA approval, but Arthrozene is produced in a GMP-certified facility. This ensures quality and adherence to safety standards.

Q: Does Arthrozene come with a money-back guarantee?

A: Arthrozene offers a 365-day money-back guarantee, allowing users to try it risk-free. Refunds are available if the product does not meet expectations.

Q: Where should I buy this product from?

A: You can purchase it on Amazon. Be sure to check the pricing on different platforms, as it may differ.

What Do the Arthrozene Customer Reviews Say?

Many users have shared positive experiences with Arthrozene, highlighting noticeable improvements in mobility, flexibility, and overall joint comfort. With over 262,972 satisfied customers, Arthrozene continues to be a trusted choice for natural joint support.

Michael Thompson shared that Arthrozene made a noticeable difference after trying multiple supplements. He experienced less knee stiffness and could walk without discomfort. Though the price was high, he felt the relief was worth it.

Angelo Sapia described how, after three knee surgeries, Arthrozene helped ease pain within weeks. He noted that stopping the supplement led to pain returning, confirming its effectiveness for him.

Jeffrey Mats, a long-term user, mentioned it lessened his arthritis-related pain, though it did not eliminate it. After trying other options, he returned to Arthrozene, finding it more effective than competitors.

Additional Testimonials from Verified Buyers (from the official website):

“I am a 52-year-old woman who has been doing fairly extreme workouts for the last ten years. My knees have always bothered me from old injuries (one from basketball and the other from a horseback riding injury). One or the other knee has been swollen most of the time in the last few years. After a week of taking Arthrozene both knees were feeling much better. I have been able to return to deep lunges, squats, and plyo-jumps with no pain. My neck and back also feel better than they have in years. It has improved my life immensely!” ~ Taci Robertson, Stamford, Texas

“I have been taking Arthrozene for about 4 months. I have an ankle that I am told needs to have an ankle replacement which scared me to death. I had cortisone shots in it for years which kept me functioning. However, they got less effective as time went on, which led me to research what else I could do. Chicken comb shots have not been approved for ankles but in my research, I found this product which contains chicken comb extract so I decided to try it. At this time Arthrozene keeps me functioning and keeping the pain to a point that I can handle it. A new ankle replacement is only good for 10 years so I am trying to avoid that as long as I can. And at this point, I am doing just that.” ~ Karen Peters, Coal Valley, Illinois

In addition to the positive feedback from customers, Arthrozene also holds an A+ rating from the Better Business Bureau (BBB), reflecting its commitment to high-quality customer service and satisfaction. This rating is a testament to the company’s dedication to resolving customer concerns and maintaining a trustworthy reputation in the marketplace.

Arthrozene Review – Final Verdict

Arthrozene is a premium joint supplement that reduces discomfort, improves mobility, and supports cartilage health. Its clinically studied ingredients, such as Boswellia serrata, Hyaluronic Acid, and Type II Collagen, target inflammation, lubrication, and joint structure.

Regulatory Compliance and Safety
Manufactured following Good Manufacturing Practices (GMP) regulations, Arthrozene meets high safety and quality standards. This compliance ensures that what you’re taking is both safe and effective, giving consumers peace of mind.

Clinically Tested Ingredients
The formula boasts ingredients like Boswellia Serrata extract and Hyaluronic Acid, which are backed by clinical research. These components have shown promising results in relieving joint pain and improving joint function, making Arthrozene a scientifically grounded choice.

Rapid Results and Positive Feedback
One standout feature is that it can deliver results in as little as five days, setting it apart from many joint supplements. Customer reviews suggest noticeable improvements, though some find the price high. This is expected for a premium product with well-researched, patented ingredients.

Customer Assurance
Moreover, numerous individuals have shared success stories, praising the product for its noticeable improvement in joint health. To further reassure potential buyers, Arthrozene offers a generous 365-day money-back guarantee, a commitment that underscores their confidence in the product’s efficacy.

Whether you’re seeking a fast-acting formula or a supplement backed by research, Arthrozene presents itself as a worthwhile option, combining proven ingredients with a strong satisfaction guarantee.

Healthy joints allow us to move with ease. Joint damage can cause pain preventing you from doing the things you once loved. From aging to untreated sports injuries – many conditions lead to joint pain. A quality joint product may help reduce inflammation, repair existing tissue damage, and promote stronger joints, lessening susceptibility to future degeneration.

Below you'll find some of the most effective joint pain supplements on the market today, in our opinion.

Rating
Our Top Joint Pain Relief Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned joint pain supplements based on the available research:

JointXL Plus - Joint Health Formula
Seal
Reduces Joint Pain & Soreness*Gold Star Evidence
Enhances Comfort & Mobility*Gold Star Evidence
Prevents Joint Degeneration*Gold Star Evidence
Supports Tissue Repair *Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
BioDynamix Joint Genesis | Doctor Formulated
Reduces Pain and Stiffness*Gold Star Evidence
Improves Joint Lubrication*Gold Star Evidence
Supports Joint Function*Gold Star Evidence
Relieves Inflammation & Discomfort*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
ProJoint Plus - VitaPost | Premium Joint Support
Supports Cartilage Health*Gold Star Evidence
Supports Joint Health*Gold Star Evidence
Lubricates Stiff Joints*Strong Evidence
Supports Joint Mobility*Gold Star Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Relief Factor | Best Pain Relief Supplement
Relief Aches and Pains*Gold Star Evidence
Reduces Inflammation*Strong Evidence
Protect Joints Damage*Strong Evidence
Support Immune System*Gold Star Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

4
Customer Reviews for Arthrozene

Arthrozene Review 2025: Shocking Results or Hype? Find Out!

Customer Reviews & Ratings

4.7 out of 5

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  1. Terry Morris




    Moved easier than i have in years
    I’ve tried glucosamine and turmeric and they barely touched the stiffness in my knees. But this? This gave me a noticeable difference around week 4. Walking downstairs isn’t a dreaded task anymore, and i even took my dog for a longer walk last weekend with no sharp twinges….
    Not 100% pain-free, but i feel like i’m getting part of my mobility back, and that’s huge for me.
  2. Michael Thompson




    Finally, a Joint Supplement That Works!
    I’ve tried several joint supplements over the years, but Arthrozene has truly made a difference for me. Within a few weeks, I noticed less stiffness in my knees, and my mobility has improved significantly. I can now go on long walks without discomfort, which wasn’t possible before. The fact that it contains natural ingredients like Boswellia and Type II Collagen gives me confidence in its quality. The price is a bit high, but for the relief it provides, I believe it’s worth it. Definitely sticking with this one!
  3. Angelo Sapia




    Works for me but is pricey
    Had 3 knee operations. I was told that I needed a new knee. Purchased a 3-month supply. Started taking it. In about 1.5 weeks knee pain began to lessen. About 1 month all pain was gone. I stopped taking it. And 3 weeks later I was in pain again. So I started taking it again and the pain is gone. Works great for me. Just wish it was cheaper.
  4. Jeffrey Mats




    This Product Works for Me!
    I have used Arthozene for over 5 years. I have had 3 meniscus knee surgeries which left me with arthritis. Once I started Arthozene, it took 2 weeks to see some of the pain go away. It did not relieve all my pain but definitely lessened it. Over the years I tried other products to replace Arthozene, such as Relief Factor, but went back to Arthozene. I tried their Golden Guard, and it did not do anything for me, and the company refunded my purchase. Everyone body reacts differently to supplements; my body seems to react better to Arthozene.

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Arthrozene Ques and Ans

  • Q: How often in a day can you take the pill?

    A: Arthrozene recommends taking one pill per day with a glass of water on an empty stomach for best results.

  • Q: Where do you send your product to get a refund.

    A: To get a refund for Arthrozene, you need to contact their customer support center at 800-392-4727 or email them at support@arthrozene.com. They will guide you through the return process and ensure a prompt and courteous refund.

  • Q: I take Arthr0zone once in 24 hours no other prescriptions. could I take it twice?

    A: The manufacturer recommends taking one pill per day with a glass of water. As you are using it without a prescription, overdosing may lead to an undesirable health condition. It would be best to seek medical advice before using it.

  • Q: Does it interfere with blood thinner (Coumadin)?

    A: Arthrozene is an all-natural formula that is considered safe and extremely effective for nearly everyone. That said, if you take prescription medications or have a medical condition, we recommend that you show a bottle of Arthrozene to your physician for proper approval. You can always return it later with an Arthrozene 90-day money-back guarantee. However, do not take Arthrozene if you are pregnant, nursing, or under the age of 18.

  • Q: Does Arthrozene relieve muscle spasms in legs?

    A: Arthrozene's trademarked ingredients are each backed by multiple clinical trials and shown to soothe discomfort, muscle spasms, ease stiffness while improving flexibility and mobility.

  • Q: Does this product offer any relief for hip joint pain?

    A: Arthrozene is designed to manage joint pains, inflammation, and stiffness in the body. According to a customer review posted on BBB by John T, it states, "I just started taking Arthrozene Monday, April 5, 24 hours later, I awoke & found my right hip, the only one I have is feeling no pain. I have bone on the bone this hip. The other hip failed 4 hip replacements, so I do not have a hip, the pain that I normally have has been reduced significantly. Both shoulders have bone on bone, are feeling significantly better. My right ankle which was crushed in 1995, is feeling better. The true test was passed, yesterday, I went out to cut my compass grass down, I have 12 in my backyard, 4 to 5 feet high, I cut down 4, but I ran out of gas. I am 80 years old and haven't much physical activity, but I am pleased that I could accomplish that. I rate a 5-star rating" While others found it is a complete waste of money.

  • Q: Is your product safe to take if I take blood thinners and heart medication?

    A: Some people who have taken Arthrozene with blood thinners or heart medication have had adverse reactions, such as stomach bleeding, low blood pressure, and allergic reactions. It is recommended to consult your doctor before taking Arthrozene with any other medications that you are currently taking.

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PRODUCT NAME
Arthrozene
PRODUCT BRAND
Fisico Inc
PRICE (in USD)
$69.95
ITEM FORM
Capsules
UNIT COUNT
30 Capsules
INGREDIENTS
Mobilee® Natural Chicken Comb Extract, Collavant n2® Native Collagen type II, Hydroxypropyl methylcellulose (capsule), cellulose, magnesium stearate (vegetable source), silicon dioxide.

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    8 Sources

    We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

    [1] Effectiveness and utility of hyaluronic acid in osteoarthritis: https://pmc.ncbi.nlm.nih.gov/articles/PMC4469223/
    [2] Efficacy and Safety of Aflapin®, a Novel Boswellia Serrata Extract, in the Treatment of Osteoarthritis of the Knee: A Short-Term 30-Day Randomized, Double-Blind, Placebo-Controlled Clinical Study: https://pubmed.ncbi.nlm.nih.gov/35512759/
    [3] Hyaluronic Acid: A Key Ingredient in the Therapy of Inflammation: https://pmc.ncbi.nlm.nih.gov/articles/PMC8533685/
    [4] Effects of Native Type II Collagen Treatment on Knee Osteoarthritis: A Randomized Controlled Trial: https://pmc.ncbi.nlm.nih.gov/articles/PMC4970562/
    [5] Oral hyaluronan relieves knee pain: a review: https://pmc.ncbi.nlm.nih.gov/articles/PMC4729158/
    [6] Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis: https://pmc.ncbi.nlm.nih.gov/articles/PMC7368679/
    [7] Collagen Supplementation for Joint Health: The Link between Composition and Scientific Knowledge: https://pmc.ncbi.nlm.nih.gov/articles/PMC10058045/
    [8] Beverly Hills MD Multi Hyaluronic Acid Plumping Booster: https://www.consumerhealthdigest.com/hyaluronic-acid-serums/beverly-hills-md-multi-hyaluronic-acid-plumping-booster.html

    **This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

    *Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

    Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

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