Acuplus Pain Relief Cream Reviews: Will This Inflammation Formula Decrease Your Pain?

Acuplus Pain Relief Cream is an organic formula that helps to ease muscles relieve sore inflamed muscles, repair nerve damage, and improve joint mobility.

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In This Review

What is Acuplus Pain Relief Cream?

Acuplus Pain Relief Cream is an all-natural product which aims to provide relief from sore and inflamed muscles, joints, and nerves. It contains ingredients which may heal and repair damage to these areas, improving functioning and mobility.

The manufacturer promises benefits in 5-10 minutes. The ingredients have some sicetific support, but the product seems to work well for some users and less so for others. You can also purchase this product as a roll-on or bath bomb.

How Does It Rate?

Overall Rating: 3.8
Acuplus Pain Relief CreamAcuplus Pain Relief Cream


Value for Cost

3.7/5Value for Cost

Customer Reviews

3.9/5Customer Reviews

Brand Highlights

  • The formula includes pure organic ingredients.
  • They manufacture in an FDA-certified facility.
  • The formula has a strong menthol scent.
  • The ingredients have some scientific support.


Pro Joint Plus

*All individuals are unique. Your results can and will vary.

Key Ingredients

  • Arnica Montana
  • Menthol
  • MSM
  • Boswellia Serrata
  • Glucosamine
  • Transdermal Magnesium
  • Vitamin B6
  • Willow Bark
  • IIex
  • Aloe Vera
  • Vitamin E
  • Licorice Root
  • Cetyl Myristoleate


  • Acuplus Pain Relief Cream may relieve muscle, joint, and nerve pain.
  • It could repair nerve damage and restore function.
  • The product may heal damaged joint and cartilage.
  • Acuplus Cream might lessen inflammation.
  • Acuplus Cream promises benefits in 5-10 minutes.


  • You can’t use this cream to heal wounds or damaged skin.
  • It can be harmful if it gets in your eyes.
  • Some users develop itching or skin rash.



*All individuals are unique. Your results can and will vary.

How Does It Work?

Acuplus Cream contains powerful anti-inflammatory agents which decrease swelling and pain in the joints, muscles, and nerves. The formula also has antimicrobial and antibacterial benefits which may destroy harmful microbes to prevent infections.

The anti-inflammatory properties may also help heal skin conditions. Acuplus Pain Relief Cream has powerful antioxidants which eliminate free radicals, resulting in lower oxidative stress.

This promotes healing and repair of damaged skin, as well as joint and muscle tissue. An article in Nutrition Journal discussed the potential use of antioxidants in the treatment of knee osteoarthritis [1].

Other substances like sulfur and glucosamine help to rebuild joint and cartilage tissue to improve functioning.

Acuplus Pain Relief Cream may cool and soothe the skin, and it also has rich hydration which moisturizes and could eliminate dryness. According to the Journal of the American Academy of Dermatology, skin moisturizers have therapeutic potential for preventing dryness [2].

Acuplus Pain Relief Cream Ingredients – Are they Safe & Effective?

Acuplus Pain Relief Cream Supplement Facts
Acuplus Pain Relief Cream Supplement Facts

These are some of the primary active ingredients:


This is a compound which already exists naturally in the cartilage tissue, but according to the Mayo Clinic the glucosamine included in supplements usually comes from shellfish [3].

It could help decrease pain and inflammation in the joints, and rebuild damaged joint and cartilage tissue. It also improves lubrication around the joints, decreasing stiffness and ameliorating flexibility, mobility, and range of motion.

A study in the British Journal of Sports Medicine concluded that glucosamine provides some relief from knee pain [4].

Boswellia Serrata

Extracted from a tree, this ingredient is very high in anti-inflammatory benefits which could decrease pain and swelling in joints, muscles, skin, and other bodily tissue.

An overview in the Indian Journal of Pharmaceutical Sciences examined the anti-inflammatory potential of Boswellia [5].

There’s evidence it could effectively treat osteoarthritis. It’s rich in antioxidants which may repair and heal damage, as well as improve immunity. A review in BMC Complementary Medicine and Therapies concluded that Boswellia had benefits in healing osteoarthritis [6].


Derived from the peppermint plant, menthol has a cooling sensation on the skin when applied topically which sooths and may decrease pain and swelling. There’s some evidence that it could decrease arthritis symptoms.

In addition, it has potent antioxidants which could repair damage to the joints, muscles, and skin as well as protect from UV rays. A study in the Journal of Geriatric Physical Therapy found partial support for the benefits of menthol in decreasing the pain of knee osteoarthritis [7].



*All individuals are unique. Your results can and will vary.

Frequently Asked Questions (FAQs)

Q: What Sets It Apart From the Competition?

A: On the positive side, the formula includes mostly ingredients with some scientific support. They are also unique in that they offer the cream in different formats like a roll-on or bath bomb.

On the other hand, it has a powerful scent some users will not like, while some of the other brands offer no scent.

Q: Where Can I Buy Acuplus Pain Relief Cream?

A: You can buy Acuplus Relief Cream from the manufacturer’s official site, and from several other online retailers like Amazon. It may also be available in some stores.

The official site offers free shipping for orders over $50. The prices for the product and its variations are as follows:

  • 1 Acuplus Pain Relief Cream (4 ounce jar) – $34
  • 1 Acuplus Pain Relief Cream (2 ounce jar) – $18.49
  • 3 Acuplus Pain Relief Cream (4 ounce jar) – $93.50
  • 6 Acuplus Pain Relief Cream (2 ounce jar) – $96
  • 1 Acuplus Pain Relief Cream (3 ounce roll-on) – $24.95
  • 3 Acuplus Pain Relief Cream (3 ounce roll-on) – $68
  • 3 Acuplus Bath Bomb (4.5 ounce) – $18
  • 12 Acuplus Bath Bomb (4.5 ounce) – $54
  • Acuplus Pain Relief Combo (1 cream, 3 bath bomb, 1 roll on) – $69.95

Q: Is It Cruelty-Free?

A: The manufacturer is a company called Innovations For Wellness LLC, and they are not cruelty-free according to the PETA site. They may test on animals, or work with suppliers or other companies who do.

Q: How Do You Apply It?

A: The cream is suitable for adults and children 2 years of age and older. For children under 2, seek a doctor’s approval before applying. Take a generous amount and rub it into the affected region up to 3-4 times daily. Do not put on open wounds or damaged skin.

Q: What is the Return Policy?

A: The manufacturer has a 100% lifetime guarantee for Acuplus Pain Relief Cream and all related products. If you are not happy with the product at any time, just contact customer service and they’ll guide you through the refund process.


Acuplus Pain Relief Cream Reviews from Customers

The reviews for Acuplus Pain Relief Cream were moderately good, with many users saying the formula did provide relief from pain and inflammation.

However, some customers got less benefits, and there was some mention of skin reactions from a few users. Here are some of the comments:

Works Well

Got this for ankles and feet. Really relieved pain well. – Cathy E.

Did Not Help

This product did not seem to help the back pain that extended down the legs. – Garyn

Good Relief

Following so many reviews, decided to go for it and buy it after all. It’s good as relief for the pain some days on my shoulder and arm caused by bursitis. Doesn’t smell that bad, and it really works, even if later the pain comes back. It’s not a cure, but it is a big relief. – Zoila

Causes Intense Itching!

This cause extreme itching all over my body from head to toe. Gave it to a friend, and she had the same horrible experience. – Lavan D.



*All individuals are unique. Your results can and will vary.

Final Word

Acuplus Pain Relief Cream is an analgesic formula which promises to ease pain and inflammation of the muscles, joints, and nerves, as well as heal damage. The formula includes a strong selection of ingredients which may help some users. It has the strong scent of menthol which is not popular with everyone.

The Acuplus reviews offered a mix of opinions about this formula. Some got great pain relief benefits, while others said it had little impact on lessening their symptoms. There was some mention of skin reactions from a few of the customers.

This cream contains pure organic ingredients, but some users could experience an ingredient allergy or skin reaction. If this occurs, stop using the cream immediately and see a dermatologist if you think it’s necessary.

Bones are connected by joints, which allow us to move with ease. Joint damage can cause pain preventing you from doing the things you once loved. Topical joint relief products tend to work more quickly, helping to relieve pain directly in the affected area compared to products taken orally. A topical joint pain relief product should be evaluated on its: potential to block the transportation of pain signals, potential to act as a counterirritant to reduce soreness and Quality of Ingredients* backed by clinical research.

Below you’ll find some of the most effective topical joint pain products on the market today, in our opinion.

Our Top Joint Pain Relief Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned joint pain relief gels, gummies, and creams based on the available research:

Well Care Botanicals | Hemp Extract Pain Relief Cream
Remove Inflammation & Soreness*Gold Star Evidence
Pain-Relieving Benefits*Gold Star Evidence
Supports Cartilage and Tissue*Gold Star Evidence
Rapid Pain Relief*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Barker Wellness | Cannabinoid-Infused Products
Nurtures Body & Mind*Gold Star Evidence
Targets Sleep & Focus*Strong Evidence
Wide Range of Products*Gold Star Evidence
Natural and Organic*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Aspercreme | Best Pain Relief Cream
Non-Greasy Cream*Gold Star Evidence
Relieves Arthritis Pain*Strong Evidence
Supports Joint & Muscles*Strong Evidence
Fast-Acting Formula*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Acuplus Pain Relief Cream

Acuplus Pain Relief Cream Reviews: Will This Inflammation Formula Decrease Your Pain?

Customer Reviews & Ratings

3.0 out of 5

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  1. Kim H.

    Works but costly....
    My knee twisted, and the agony was excruciating. When I used this lotion, I felt immediate alleviation. For the first few days, I did need to apply it at least twice daily. However, it reduced the discomfort till the injury healed. only thing that bother me is the cost of this product.

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Acuplus Pain Relief Cream
2 Ounce
Arnica Montana, Menthol, MSM, Boswellia Serrata, Glucosamine, Transdermal Magnesium, Vitamin B6, Willow BarkIIex, Aloe Vera, Vitamin ELicorice Root, and Cetyl Myristoleate.

7 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Benefits of antioxidant supplements for knee osteoarthritis: rationale and reality : Benefits Of Antioxidant Supplements For Knee Osteoarthritis: Rationale And Reality | Nutrition Journal | Full Text (
[2] Skin Moisturizers: Therapeutic Potential And Preventative Maintenance Of Dry Skin:
[3] Glucosamine : Glucosamine - Mayo Clinic
[4] The effect of glucosamine supplementation on people experiencing regular knee pain : The Effect Of Glucosamine Supplementation On People Experiencing Regular Knee Pain | British Journal of Sports Medicine (
[5] Boswellia Serrata, A Potential Anti-inflammatory Agent: An Overview:
[6] Effectiveness Of Boswellia And Boswellia Extract For Osteoarthritis Patients: A Systematic Review And Meta-Analysis:
[7] The Effect of Either Topical Menthol or a Placebo on Functioning and Knee Pain Among Patients With Knee OA:

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

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