In This Review
ActivICE- Overview
ActivICEis a brand that offers temporary pain relief from arthritis, injuries, or muscle discomfort. It aims to cool and numb the area, decrease inflammation, and ease soreness.
ActivICE may also moisturize the skin, prevent infection, and heal skin conditions. It’s one formula available as either an ActivICE Gel, spray, or roll-on.
How Does It Rate?
Brand Highlights
- The products include only natural, organic ActivICE ingredients.
- The brand is free of parabens and dyes.
- The products on the official site are only available to U.S customers.
- The manufacturer is Medline At Home, which makes and delivers hospital-quality health care products to customers.
Key Ingredients
- Menthol
- MSM
- Eucalyptus Oil
- Glucosamine
- Peppermint Oil
Pros
- ActivICE may decrease pain in joints, muscles, and minor injuries.
- These products may lower inflammation.
- The brand could cool and soothe the skin.
- ActivICE might moisturize and eliminate dry skin.
- The manufacturer promises fast benefits.
Cons
- The ActivICE ingredients list is less rich compared to other natural pain products.
- It has a strong scent which some users do not like.
- Some customers may develop an allergic skin reaction.
Highlighted Products
ActivICE Gel

Cold As Ice
Key Ingredients: Menthol, MSM, Eucalyptus Oil, Glucosamine, Peppermint Oil
Price: $10.45
Best For: Cooling and Soothing Joints, Muscles, and Injuries
What It Does: Reduces Pain and Swelling, Repairs Damage to Muscles and Joints, Decreases Stiffness, Moisturizes, and Soothes Skin
ActivICE Spray

Spray and Soothe
Key Ingredients: Menthol, MSM, Eucalyptus Oil, Glucosamine, Peppermint Oil
Price: $12.95
Best For Reducing Pain and Swelling in Muscles, Joints, and Injuries
What It Does: Reduces Pain and Swelling, Repairs Damage to Muscles and Joints, Decreases Stiffness, Moisturizes and Soothes Skin
ActivICE Roll On

Keep on Rolling
Key Ingredients: Menthol, MSM, Eucalyptus Oil, Glucosamine, Peppermint Oil
Price: $9.95
Best For Reducing Pain and Swelling in Muscles, Joints, and Injuries
What It Does: Reduces Pain and Swelling, Repairs Damage to Muscles and Joints, Decreases Stiffness, Moisturizes, and Soothes Skin
How Does It Work?
ActivICE contains ingredients with analgesic properties, which may lessen pain by both cooling and numbing the area and blocking nerve cells for pain receptors.
An article in Evidence-Based Complementary and Alternative Medicine discussed natural analgesic products [1].
It has anti-inflammatory agents which decrease joint and muscle swelling, and could also help to heal skin conditions. Rich in antioxidants, it may destroy free radicals leading to lower levels of oxidative stress.
This promotes the repair and healing of bodily tissue and strengthens the immune system. A study in Osteoarthritis and Cartilage found that antioxidant levels are lower in osteoarthritis compared to healthy joints [2].
Other substances like sulfur and glucosamine may help rebuild damaged cartilage tissue for improved functioning. Lubricating substances could decrease joint stiffness and enhance flexibility and mobility.
An article in Clinics in Rheumatic Diseases discussed joint lubrication [3]. The hydration could also moisturize the skin and get rid of dry patches. ActivICE also has anti-microbial properties which kill harmful bacteria to prevent infection.
ActivICE Ingredients – Are they Safe & Effective?
These are some of the primary active ActivICE ingredients:
Glucosamine
This is an amino sugar that exists as a natural component of the cartilage. The glucosamine in supplements often comes from shellfish. It may decrease pain and inflammation, and help repair and rebuild damage to the tissue.
An article in Arthritis discussed glucosamine in the treatment of osteoarthritis [4]. It may also help to lubricate and protect the joints, improve flexibility and mobility, and boost general joint and cartilage health.
A review in Therapeutic Advances in Musculoskeletal Disease found support for the use of glucosamine in decreasing pain and inflammation in knee osteoarthritis [5].
MSM
Methylsulfonylmethane is a sulfur-based chemical that exists naturally in the body. It repairs and rebuilds damaged joints and cartilage for improved functioning and a decrease in symptoms like pain, stiffness, and inflammation, as we said in our review of Quick Relief.
A study in the International Journal of Medical Science on people with joint degeneration concluded that MSN could improve functioning and decrease symptoms [6].
It may also prevent cartilage tissue from further breaking down. MSM could also lessen muscle damage after a workout and speed up recovery.
Menthol
This bioactive ingredient from the peppermint plant has analgesic properties. It is cooling and numbing on the skin, soothing, and could decrease pain and inflammation.
It may ease joint and muscle discomfort, and heal minor injuries and wounds. While it has a powerful scent, its properties make it a common ingredient in many topical pain relief products.
A review in the Journal of Clinical Pharmacy and Therapeutics examined the function and effect of menthol in topical pain-relief products [7].
How Do the Products Rate?
Product | Rating |
---|---|
ActivICE Roll-On | 3.6 |
ActivICE Gel | 3.9 |
ActivICE Spray | 3.7 |
Frequently Asked Questions (FAQs)
Q: Is ActivICE Worth It?
A: The prices for the brand are more or less average, and based on the ActivICE reviews it does provide benefits to some users. However, the formula is missing some key ingredients that other similar products have, so you can likely find a richer product for a similar price.
Q: What is the Return Policy?
A: The manufacturer has a 90-day limit on their return policy. If you’re not happy with your order contact customer service at 1-800-307-8386 for instructions on how to return it.
If you send the products back within 30 days of the purchase you pay a 5% restocking fee. From 31-60 days, you pay a 10% fee and from 61-90 days you pay 20%.
Q: Is It Cruelty-Free?
A: The manufacturer, Medline At Home, is not a PETA-certified cruelty-free company, and they make no mention of this on their website. This may mean they do animal testing themselves, work with companies who do or purchase information from organizations that carry out this kind of testing.
Q: Where to Buy It?
A: If you’re an American resident, you can purchase ActivICE products through the official site by registering for an account.
However, they are also available from quite a few other online and offline retailers, like Amazon and Walmart. The manufacturer is offering free shipping for orders over $50. The prices on the official site are as follows:
- ActivICE Roll-On (3oz) – $9.95
- ActivICE Spray (4oz) – $12.95
- ActivICE Gel (4oz) – $10.45
- ActivICE Gel (32oz) – $44.95
- ActivICE Gel (1 Gallon) – $136.95
Q: What Sets It Apart From the Competition?
A: The brand offers healthcare products used in hospitals, but available to users directly and delivered to their homes. Having said that, these pain formulas are no better than any of the other brands available, and many are much more potent than ActivICE.
What Do the Reviews Say?
The reviews for ActivICE were moderately good, but opinions did vary. Some users had a very good customer experience and said these products were helpful in decreasing their pain.
Others said they provided little or no benefits, and had a strong smell. Here are a few of the customer comments, to give you a general idea of the feedback:
Cooling Out and Pain Free
Bye, bye muscle aches. Spray on hard-to-reach areas and feel the immediate chill and relief. This allowed rest from body aches especially at night. Wear at home due to the powerful smell. Happen to like it cause it smells like Vicks.~Amazon Customer
This Stuff Was a Waste of Money
You get what you pay for. It did nothing that it was supposed to do~Kimberly L.
It Works!
Was amazed! The pain from a rotator cuff injury was interfering with sleep. Sprayed it once and within a few minutes the pain was gone! How in the world did that work? But it did work!~ Barbara K.S.
It’s Okay
It does have that minty menthol smell you get with Icy Hot and Biofreeze, but felt like the results and feeling from Biofreeze were different. Not saying it was bad, but not as effective. In a pinch would get it again. –~ Joseph S.
ActivICE – Conclusion
Medline ActivICE Topical Pain Reliever is a natural formula available as a gel, spray, or roll-on product. It aims to decrease pain and inflammation in the joints and muscles, heal minor injuries, and hydrate the skin. While quality products, there are other more potent brands available for a similar cost.
The ActivICE reviews were from users with varied customer experiences. Some found this brand effective in easing their symptoms, while others said it worked poorly and was a waste of money. Some users liked the smell, but there were also people who said it was too strong.
ActivICE includes 100% organic ingredients, free of parabens, dyes, and other additives or fillers. It’s a safe brand, but some users may develop an allergic skin reaction. If you have symptoms like rash or redness, stop using ActivICE and see a dermatologist if necessary.
Healthy joints allow us to move with ease. Joint damage can cause pain preventing you from doing the things you once loved. From aging to untreated sports injuries – many conditions lead to joint pain. A quality joint product may help reduce inflammation, repair existing tissue damage, and promote stronger joints, lessening susceptibility to future degeneration.
Below you'll find some of the most effective joint pain supplements on the market today, in our opinion.
Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned joint pain supplements based on the available research:

Jessica M.