In This Review
Dermaplex Overview
Dermaplex is an anti-aging serum that claims to minimize the overall appearance of facial wrinkles and prevent new one’s foam forming. It is effective in diminishing creases that usually appear around the forehead, eyes, and mouth areas. It contains a special ingredient which claims to exert its effect by relaxing the facial muscles which, in turn, smoothens out fine lines and wrinkles.
Most information available about the product came from various anti aging cream reviews websites, as the brand doesn’t seem to have an official website.
Nonetheless, this serum is sold at $41.50 per bottle. There are free trial offers for the product, but there is no mention of any money-back or satisfaction guarantee.
What is Dermaplex?
Dermaplex is an anti-aging serum formulated to reduce the appearance of fine lines and wrinkles. It contains key ingredients like acetyl hexapeptide-8, known for its ability to mimic Botox by relaxing facial muscles, and hyaluronic acid, which helps hydrate and plump the skin.
Dermaplex claims to provide smoother, younger-looking skin by targeting the signs of aging, especially around the eyes and forehead. While it promises quick results, the effectiveness may vary among users, and it’s important to note that the product is marketed as a temporary solution, offering visible results only for a short period of time.
How Does It Rate?
Dermaplex
Brand Highlights
- Dermaplex is an anti-aging serum that is made to deliver fast acting results.
- This is meant to be a safe solution that does not produce harsh effects which can damage the skin.
- It accomplishes this by smoothing wrinkles, managing skin tone, and strengthening skin with just one single formula.
Key Ingredients
- Acetyl hexapeptide-8
- Hyaluronic acid
- Silk amino acids
- Green and white tea extracts
- Grape seed extract
- Echinacea
- Comfrey extract
- Vitamins A, B, and E
Pros
- Smooths skin, reducing fine lines and powerful anti-aging.
- Hydrates and improves skin texture with hyaluronic acid.
- Non-invasive alternative to Botox for wrinkle reduction.
Cons
- Effects are temporary and need reapplication.
- High price with short-lasting results.
- No long-term wrinkle reduction benefits.
- Only available online, with limited store availability.
- May cause irritation or dryness for sensitive skin.
- No clear money-back guarantee.
About the Brand
Dermaplex is produced by a skincare brand that specializes in anti-aging solutions. While the company behind the product provides limited information on its website, Dermaplex claims to combine advanced ingredients like acetyl hexapeptide-8 and hyaluronic acid to offer users a non-invasive alternative to Botox.
The brand emphasizes skin hydration and smoothness, targeting visible signs of aging. However, despite these claims, there is limited information on the manufacturer’s overall reputation or any certifications to support its credibility in the skincare industry.
How Does Dermaplex Work?
The primary active ingredient of Dermaplex, which is acetyl hexapeptide 8 works by preventing the facial muscles from contracting repeatedly, leading to fewer creases in the face.
This effect is similar to that produced by Botox, without the use of painful injections.
It works well on the forehead and mouth areas, as well as on the delicate eye area. In fact, it is also suitable for use in other parts of the body. Regular use of this serum results to noticeably younger and more radiant skin.
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Dermaplex Ingredients – Are they Safe & Effective?
Acetyl hexapeptide-8 –
Minimizes facial creases by preventing facial muscles from repeatedly contracting.[1]
Hyaluronic acid –
Traps moisture and thus makes the skin softer, smoother, and fuller. Infact, an abstract published by Dermato Endocrinology states “The key molecule involved in skin moisture is hyaluronic acid (HA) that has unique capacity in retaining water.”[2]
Silk amino acids –
Improves cell function and promotes cell renewal; it also has natural moisturizing and antioxidant properties[3]
Green and white tea extracts –
Loaded with amino acids and antioxidants that induce tissue repair, while also protecting the skin the skin from further damage. A Study found both green tea and white tea to be potential photoprotective agents that may be used in conjunction with established methods of sun protection.[4]
Grape seed extract –
Rich in antioxidants that are beneficial for skin health, it aids in reducing inflammation, improving collagen production, and enhancing skin elasticity, leading to a smoother, more youthful appearance. As mentioned in our ReActivate skin reviews, Grape seed extract is polyphenolic compounds further contribute to protecting the skin from UV damage and maintaining overall skin integrity.
Echinacea –
Has strong anti-aging properties that noticeably reduce fine lines and wrinkles; it is also a disinfectant that protects and soothes irritated skin. However, according to a study, Echinacea purpurea is found to be effective in improving skin hydration and reducing wrinkle, but showed low storage stability.[5]
Comfrey extract –
Known for its skin nourishing and moisturizing properties.
Vitamins A, B, and E –
Antioxidant vitaminsthat also serves to moisturize, nourish, and heal the skin.[6]
How to use Dermaplex?
- Cleanse your face thoroughly with a gentle cleanser.
- Apply a small amount of Dermaplex serum to your face, focusing on areas with fine lines and wrinkles.
- Massage gently until the product is absorbed.
- Use it daily, ideally at night, to maintain smoother skin.
- Follow with your regular moisturizer to lock in hydration.
Benefits Of Dermaplex
- Reduces Wrinkles: Helps temporarily smooth fine lines and wrinkles, giving skin a more youthful appearance.
- Hydrates Skin: Hyaluronic acid in the formula helps hydrate and plump the skin, improving texture.
- Non-Invasive: A safe, needle-free alternative to Botox, offering a temporary solution for wrinkle reduction.
- Improves Skin Smoothness: Regular use may leave the skin feeling softer and looking more even.
Side Effects
Some users may experience skin irritation when using Dermaplex, including redness, dryness, or a tingling sensation, particularly those with sensitive skin. Since the serum offers temporary effects, users will need to reapply it regularly to maintain smoother skin, which might be inconvenient for those looking for a more lasting solution.
Additionally, some active ingredients, like acetyl hexapeptide-8, may cause sensitivity or irritation for individuals who are particularly sensitive to peptides. While these side effects are generally mild, it’s important to monitor your skin’s reaction and discontinue use if irritation persists.
Safety Of Dermaplex
Dermaplex is generally safe for most skin types, but if you have sensitive skin, it’s recommended to perform a patch test before full application to avoid any adverse reactions. As with many anti-aging products, it’s advised that pregnant or breastfeeding women consult with a healthcare professional before using Dermaplex.
While the product is dermatologist-tested, individuals with allergies or sensitivities to any ingredients should avoid it. Additionally, since some of the active ingredients in Dermaplex can increase sun sensitivity, it is essential to apply a broad-spectrum sunscreen during the day to protect the skin from UV damage.
Dermaplex FAQ’s
Q: How Should You Take Dermaplex?
A: Using this product is very simple. All you have to do is gently massage it onto a freshly-washed face in the morning and at night. Wait for the product to dry before applying makeup or any other skincare product.
Q: Can Dermaplex be used around the eyes for crow’s feet?
A: Yes, Dermaplex can be applied around the eyes to target crow’s feet and fine lines. Its smoothing and hydrating effects make it an ideal choice for delicate skin areas. However, avoid getting it too close to the eyes to prevent irritation.
Q: Will Dermaplex help with deep forehead wrinkles?
A: Dermaplex can temporarily reduce the appearance of fine lines and mild wrinkles, including those on the forehead. However, for deeper wrinkles, the results may be less noticeable, and reapplication is required for ongoing smoothing.
Q: After applied, how long does Dermaplex last?
A: In a 27-person test when image analysis was used, temporary improvement continued to be seen for up to 12 hours. For the best results, the manufacturer recommends using Dermaplex anti-aging cream for at least 3 months.
Q: Where should I buy Dermaplex from online?
A: It’s available on Amazon and Walmart, but check for price variations before purchasing.
Q: What are some similar products to Dermaplex?
A: Similar products include Natura Beaute and Angel Lift.
Q: What are the side effects of Dermaplex?
A: The manufacturer of Dermaplex claims that their product doesn’t produce any side effects, because it contains ingredients that have been proven to be safe.
But since trial samples are being offered, it would be best to try the product first before buying it at its full price.
If any adverse reactions occur, don’t use the product and instead opt for another – like the ones suggested below – that would be more suitable for your skin type.
Dermaplex Review – Final Verdict
Dermaplex is one of the many anti-aging products that claim to be as effective as Botox.
Its manufacturers say that their product has lots of satisfied users, but they don’t any proof to show.
Overall, the product may be worth considering based on the list of ingredients and the fact that there is currently a free trial offer which will allow you to try it first and see for yourself.
As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.
Below you'll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.
Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned anti-aging products and anti-wrinkle creams based on the available research:






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