Lean Gene Reviews: Does It Really Work As Advertised?

Lean Gene is a specialized energy & weight management supplement that increases metabolism & enhances energy for effective & sustainable weight management.

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In This Review

Overview of Lean Gene

According to health data, 52% of the world’s population is obese or overweight. Obesity is a disease that can lead to many health complications and is a risk factor for developing diabetes, heart disease, high blood pressure, and many other disorders. Some people, no matter how hard they try, struggle to lose weight, while others who follow the same diet lose weight without a problem. Why is that? A weight loss supplement called Lean Gene claims to have found the solution with its revolutionary product.

But is that true? Can a pill help you to lose weight? What about the ingredients? Are they safe and effective? Also, what do real customers have to say about the product? Does it really work? If you’re curious about the answer to these questions, keep reading to find the answers to these and many other questions.

What Is Lean Gene?

Inspired by people living in the village of Candido Godoi in Brazil, this is what inspired Lean Gene. For hundreds of years, the people in this village have collected plants from the Amazon rainforest and combined them to form a tincture. Then, they add a few drops to their water and drink it each morning. Lean Gene uses these plants and herbs to make their weight loss supplement to help you look years younger and lose weight.

How Does Lean Gene Rate?

Overall Rating: 4.7
Lean GeneLean Gene


Value for Cost

4.6/5Value for Cost

Return Policy

4.8/5Return Policy

Brand Highlights

  • Made in the USA.
  • Their products are formulated with natural ingredients known for their potential to support weight management and overall health.
  • Have a reputation for being a trusted brand in the weight loss industry.
  • Products may undergo rigorous quality control measures to ensure purity, potency, and safety.

Key Ingredients

  • Yerba Mate
  • Betaine
  • Cinnamon Bark Extract
  • Resveratrol
  • Chromium
  • Butyrate


  • It increases fat-burning significantly.
  • It decreases your appetite and reduces your calorie intake.
  • Helps to reduce stubborn belly fat.
  • It targets the UCP2 gene, a gene that’s inactive in most people and the gene that primarily helps people lose fat.


  • Only available online.
  • The effectiveness can vary from person to person.
  • The cost can be expensive.

You can BUY it directly from the Official Website

Who is the Manufacturer of Lean Gene?

How Does Lean Gene Work?

The Lean Gene method operates through a concise three-step sequence. Initially, it targets the UCP2 gene, a recently discovered genetic component pivotal to fat loss[1]. This gene plays a central role in weight management yet remains largely inactive in many individuals, contributing to weight loss challenges. The Lean Gene strategy focuses on reactivating the UCP2 gene to promote its activity[2].

The subsequent phase entails elevating the body’s metabolic rate, specifically the Resting Metabolic Rate(RMR). This metabolic rate signifies the pace at which the body expends fat[3]. RMR constitutes one of the two key components of metabolism, functioning during periods of rest or sleep. The Lean Gene approach aims to heighten RMR, resulting in increased calorie expenditure even during periods of inactivity[4].

The ultimate stage of this methodology revolves around curtailing the formation of adipose tissue in the body, even when following diets rich in carbohydrates or fats. Detailed exploration will reveal that the Lean Gene incorporates an array of ingredients designed to mitigate fat formation. By following this three-tiered process, the body enhances calorie utilization and facilitates the redistribution of existing fat deposits.

Lean Gene Ingredients – Are They Safe & Effective?

Yerba Mate

Hailing from South America, yerba mate is a botanical product with medicinal properties. It plays a supportive role in managing type 2 diabetes by alleviating fatigue and reducing lipid levels. The primary focal point of this extract is the UCP2 gene within the organism[5].

Yerba Mate contains the same antioxidants, caffeine, and several other nutrients as green tea. Some research suggests that it may enhance physical performance, boost energy, and support weight loss. – Amy Ritcher, RD, Nutrition


Betaine possesses lipotropic qualities, thereby accelerating metabolism and breaking down fats into usable energy sources. This supplement’s components aid in regulating insulin sensitivity and maintaining blood sugar levels.

Choline & Inositol

Choline acts as a lipotropic agent that directly interacts with the gene responsible for fat production. In addition to addressing the root causes of despondency, inositol contributes to appetite and weight management. As indicated by the national health and nutrition study, choline derived from a daily dietary intake can mitigate fat accumulation[6].

Cinnamon Bark

This substance promotes optimal glucose levels and enhances insulin and metabolic functionality. It continues to regulate enzymes that inhibit the body’s fat storage mechanisms. Additionally, it bolsters the production of UCP2 Lean Gene, thus enhancing metabolism.

Cinnamon bark contains bioactive compounds like cinnamaldehyde and cinnamic acid, which have been shown to activate thermogenesis and increase fat burning in animal studies. While human studies are limited, incorporating Cinnamon Bark into a balanced diet and exercise regimen may support weight loss efforts. – Dr. Jason Kim, Endocrinologist


Derived from plants, the natural antioxidant Polyphenol offers various positive health effects. Two extracts sourced from this polyphenolic compound, namely grape seed extract and green tea, aid in facilitating fat breakdown and curbing appetite[7].


Chromium diminishes cravings and aids in maintaining healthy glucose levels. It is pivotal for elevating metabolism and adhering to a nutritious diet. By enhancing insulin equilibrium, it simplifies weight loss efforts.

Chromium is a trace mineral that helps regulate blood sugar levels and may influence energy metabolism. Including chromium-rich foods or supplements in the diet could aid in weight management by supporting stable blood sugar levels and reducing the risk of overeating. – Dr. James Lee, Dietitian


Butyrate fosters the maintenance of balanced gut microbiota and raises resting energy levels. It finds utility in managing obesity and supporting the body’s enhanced fat metabolism. Furthermore, it regulates insulin sensitivity and functions as an anti-inflammatory agent, quelling specific immune responses to facilitate weight loss[8].

If you’re interested in losing belly fat, here’s an article titled Top 5 Ways To Lose Menopausal Belly Fat Soon – Try It!

Verdict: We approve of the ingredients because they are backed by science and are all natural.

You can BUY it directly from the Official Website

Benefits, & Safety of Lean Gene

Benefits of Lean Gene

Appetite Suppression: Some weight loss supplements may contain ingredients that help suppress appetite, leading to reduced calorie intake.

Increased Metabolism: Certain supplements may contain stimulants or thermogenic ingredients that can boost metabolism, potentially aiding in fat burning.

Enhanced Fat Oxidation: Ingredients like green tea extract or caffeine may promote the breakdown of fat cells, facilitating weight loss.

Improved Energy Levels: Some weight loss supplements contain ingredients that can increase energy levels, which may be beneficial for supporting physical activity and exercise routines.

Safety of Lean Gene

Quality of Ingredients: It’s essential to choose weight loss supplements from reputable manufacturers with high-quality ingredients and good manufacturing practices.

Potential Interactions: Weight loss supplements may interact with medications or exacerbate certain health conditions. It’s crucial to consult with a healthcare professional before starting any new supplement regimen, especially if you have underlying health issues or are taking medications.

Adverse Effects: Some weight loss supplements may cause side effects such as jitteriness, insomnia, increased heart rate, digestive discomfort, or allergic reactions in sensitive individuals.

Potential Side Effects of Lean Gene

Digestive Issues: Some ingredients in weight loss supplements, such as fiber or certain herbal extracts, may cause digestive upset, including bloating, gas, or diarrhea.

Cardiovascular Effects: Stimulants like caffeine or synephrine found in some supplements may increase heart rate and blood pressure in susceptible individuals.

Insomnia: Stimulant-containing supplements may interfere with sleep patterns, leading to insomnia or disrupted sleep.

Allergic Reactions: Some individuals may be allergic to certain ingredients in weight loss supplements, leading to allergic reactions such as itching, rash, or swelling.

Lean Gene Frequently Asked Questions

Q: What is the cost of Lean Gene?


  • 30-Day Supply – One bottle of Lean Gene is at $59 per bottle + save $59 with each purchase + free shipping.
  • 90-Day Supply – Three bottles of Lean Gene are at $49 per bottle + save $207 with each purchase of these bottles + free shipping.
  • 180-Day Supply – Six bottles of Lean Gene are at $44 per bottle + save $444 with each purchase of these bottles + free shipping.

Q: Does Lean Gene have a return policy?

A: Yes, Lean Gene has a 60-day money-back return policy.

Q: How do I take Lean Gene?

A: Take 2 capsules daily with water.

Q: Who can take Lean Gene?

A: This product is suitable for anyone over the age of 18 who is not pregnant or nursing. If you are taking prescription medications, it’s always best to contact your physician before starting Lean Gene.

Q: Are there any adverse side effects?

A: There have been no reported side effects from this weight loss supplement.

Q: How much weight can you lose on Lean Gene?

A: It typically takes three weeks to start seeing results. We’ve had people claim they lost up to 70 lbs in a year. However, it’s important to know that it is not typical, and results vary based on the consumer.

What Do the Lean Gene Reviews Say?

We like to use Amazon for our customer reviews instead of the official website because it is more unbiased and you get a true picture of how the product works.

With just over 30 ratings, Lean Gene has 4.4 out of 5 stars.

A top four-star rating states that the product is good not great and goes on to say

“ I notice a difference in my energy during the day, but it’s not too much, really. It does the job but not enough to make you hyper.”

Another four star rating by Amazon Customer states they’re a first time user and goes on to state,

Another four star rating by Amazon Customer states they’re a first time user and goes on to state,

A three star review by ELS states there’s no noticeable difference

“When you take them you do feel energy but it’s kinda fast overwhelming where it started giving me headaches and there is a weird taste when taking them but don’t think there for me maybe for someone else.”

A one star review by Gloria Lopez states that the pill didn’t do anything.

“Bought in April, it’s June and no results save your money. Transform actually works better.”

We approve of these reviews because they are mixed and give you a good picture of how this product works.

Lean Gene Reviews – Conclusion

Lean Gene targets your UPC2 gene to increase your resting metabolism. The ingredients in this formula help to keep your body from storing fat while increasing fat burning. The metabolic support supplement helps you to feel more energetic, reduces cravings, regulates your blood sugar, and enhances cognitive function.

Where To Find It?

You can BUY it directly from the Official Website

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

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Customer Reviews for Lean Gene

Lean Gene Reviews: Does It Really Work As Advertised?

Customer Reviews & Ratings

5.0 out of 5

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  1. Adward

    My go-to support for achieving and maintaining a healthy weight!!!
    Lean Gene has been a game-changer in my weight management journey. As someone who has struggled with maintaining a healthy weight, finding a supplement that actually works was a priority for me. With Lean Gene, I’ve experienced a noticeable reduction in my appetite, which has helped me make better food choices and stick to my calorie goals. I also appreciate that it doesn’t give me any jittery feelings or crashes like some other products I’ve tried.

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Lean Gene
Lean Gene
60 Capsules
Yerba Mate, Betaine, Cinnamon Bark Extract, Resveratrol, Chromium, and Butyrate.

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    8 sources

    We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

    [1] Uncoupling Protein 2: A Key Player and a Potential Therapeutic Target in Vascular Diseases: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661070/
    [2] Role of Uncoupling Protein 2 Gene Polymorphisms on the Risk of Ischemic Stroke in a Sardinian Population: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147365/
    [3] Examining Variations of Resting Metabolic Rate of Adults: A Public Health Perspective: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535334/
    [4] Role of resting metabolic rate and energy expenditure in hunger and appetite control: a new formulation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424457/
    [5] Yerba Mate—A Long but Current History: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622869/
    [6] Choline supplements: An update: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025538/
    [7] The Role of Polyphenols in Human Health and Food Systems: A Mini-Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160559/
    [8] Potential beneficial effects of butyrate in intestinal and extraintestinal diseases: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070119/

    **This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

    *Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

    Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

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