Drmtlgy Peptide Night Cream Review: Wake Up With Refreshed, Youthful-Looking Skin

Drmtlgy Peptide Night Cream is a deeply hydrating peptide night cream which tightens the skin, eliminates signs of age, and boosts a dry, dull complexion.

In This Review

What is Peptide Night Cream?

Peptide Night Cream is an 100% organic formula that promises to moisturize deeply, getting rid of dullness and flaky, dry skin. It’s rich in peptides that help tighten the complexion, improve elasticity, and smooth wrinkles and lines while you sleep.

Highly recommended by dermatologists everywhere, I myself use it every night and can attest to its great benefits. Let’s look at some of the details of Drmtlgy Peptide Night Cream.

Overview of Peptide Night Cream Review

Overall Rating: 4.9
Peptide Night Cream
Drmtlgy Peptide Night Cream



Value for Cost

4.8/5Value for Cost

Return Policy

4.9/5Return Policy



Brand Highlights

  • Peptide Night Cream is suitable for all skin types.
  • This cream comes highly recommended by many dermatologists.
  • The brand is 100% cruelty-free.
  • Drmtlgy Peptide Night Cream is free of fragrance, gluten, parabens, and sulfates.

Key Ingredients

  • Shea Butter
  • Ceramides
  • Peptides
  • Allantoin
  • Vitamin E
  • Cholesterol


  • Peptide Night Cream can tighten and firm the skin.
  • It enhances skin texture.
  • Peptide Night Cream can deeply hydrate and eliminate dry skin.
  • This formula can smooth wrinkles and fine lines.
  • Peptide Night Cream Drmtlgy repairs damage to the complexion.


  • The results will vary for different users.
  • This is a popular cream that may sometimes run low stock.
  • There are no free samples available.
You can BUY it directly from the Official Website

About the Brand

The manufacturer of Peptide Night Cream is a highly reputable skin care company called Drmtlgy LLC, located in Los Angeles, California. Founded in 2017, this is a high-level producer of a range of skin care products, all using 100% pure organic, medical grade ingredients.

How Does Peptide Night Cream Work?

Peptide Night Cream is high in peptides, true to its name. These are amino-acid chains which stimulate collagen production, replacing some of the amount that diminishes with age. This can lift and tighten the skin, improve elasticity, and smooth wrinkles and fine lines.

A study in Skin Pharmacology and Physiology concluded that bioactive collagen peptides could have photo-protective effects and improve overall skin health (1).

This is an incredibly hydrating cream which can moisturize and eliminate dry dull, flaky skin. It also gives the complexion more volume, which can further diminish lines. Peptide Night Cream also forms a protective barrier which keeps in moisture and locks out harmful agents like bacteria.

The cream is high in anti-inflammatory agents, which can decrease redness and swelling and may help heal some skin conditions. It is also replete in antioxidants which destroy harmful free radicals and diminish oxidative stress, promoting stronger skin immunity, repairing damage, and protecting it from harmful environmental agents like dust.

An article in Plastic and Reconstructive Surgery discussed the role of antioxidants in skin care (2).

What Are the Ingredients in Peptide Night Cream?

These are some of the primary active ingredients in Peptide Night Cream:


These are fatty lipids which make up about 30-40% of the outer layer of the dermis. They are very hydrating, and they also form a protective film which keeps in hydration, and prevents bacteria and other harmful agents from entering.

Ceramides help to eliminate dry, dull, flaky skin. An article published in the
American Journal of Clinical Dermatology discussed the key role that ceramides play in skin function (3).

Vitamin E

This is one of the most potent ingredients in skin care, and can repair damage to the skin and protect it from harmful agents like UV rays and pollution. It nourishes the complexion, and could decrease inflammation and help treat skin conditions and wounds.

This nutrient may also provide some hydrating properties and eliminate dryness. An article in the
Journal of Molecular Medicine explored the role that Vitamin E plays in healing normal and damaged skin (4).

Shea Butter

This fatty substance from the African shea tree can hydrate the skin, and get rid of dryness and dullness. It’s very high in anti-inflammatory agents which can decrease redness and swelling on the skin, and is a common treatment for skin conditions.

Shea butter is also full of antioxidants, which repair damage and protect the complexion from UV rays. A study in
The Journal of Allergy and Clinical Immunology confirmed that shea butter may be an effective emollient for eczema (5).

Peptides – The formula includes a range of peptides, which are chains of amino acids that stimulate collagen and elastin production. This can tighten the skin, improve elasticity, and smooth wrinkles and lines.

Peptides also have hydrating and soothing properties and can help eliminate dry, dull skin. An article in Cosmetics discussed topical peptide treatments with effective anti-aging benefits (6).

You can BUY it directly from the Official Website

Who Should Buy Peptide Night Cream?

This is an ideal anti-aging formula for anyone who is either looking to reduce the signs of age, including wrinkles and dryness. It’s also a good product for women who have not developed these signs yet, but want to protect their complexion and slow aging.

Peptide Night Cream FAQ

Q: What Do the Peptide Night Cream Reviews Say?

A: I read through may of the Peptide Night Cream reviews, and it led me to conclude that this is a very worthwhile cream. Users mentioned that it made their skin soft and supple, removed fine lines and wrinkles, and rejuvenated dry skin.

I’ve picked out some of the top Drmtlgy Peptide Night Cream review postings so you could get an idea of the user feedback.

Night Cream

I love this cream! I am 60 years old, and it keeps my skin soft, supple and looking young! I always get a lot of compliments on my skin! I have ordered several refills! – Kary B.

Soothing Cream

I use this cream every night on my face & neck! It leaves my skin very soft & smooth! Great product & price! – C. Miller

Best Moisturizer

This is the best nighttime moisturizer I’ve ever tried. First of all, it doesn’t leave you greasy at all, which is uncommon in all the brands I’ve tried. It is unscented, absorbs quickly, and a little goes a long way. Highly recommend it if you’re looking for a new night cream! – Jenny J.

Great Night Cream

I love using this cream at night; it makes my skin soft and moisturized. – Sherin

Q: When to Use Peptide Cream?

A: Although this is primarily intended as a night cream, the manufacturer states that you can use it twice a day if you wish. Take a generous amount and spread it on your face or your body. Allow it to dry for a few minutes before applying other products.

Q: What is the Peptide Night Cream Return Policy?

A: Drmtlgy LLC has a 60-day return policy. If you are not happy with Peptide Night Cream, contact the company for instructions, then send it back within 60 days of the original date of purchase. You should get a full refund, excluding the return shipping fees.

Q: Is Peptide Night Cream Cruelty-Free?

A: Yes, the Drmtlgy brand is 100% cruelty-free. They will never test any of their skin care on animals, nor will they have associates or suppliers who do.

Q: Where to Buy Peptide Night Cream?

A: You can purchase this peptide-based night cream on the manufacturer’s official website, and from several other online retailers including Amazon. On the official site you can make a one-time purchase for $46, or subscribe and save 20% for a price of $37.

Q: What Sets Peptide Night Cream Apart From the Competition?

A: The main thing that makes Peptide Night Cream Drmtlgy unique is the incredibly rich formula which is superior to many other night creams on the market. It’s a powerful blend which has much to offer the complexion in terms of anti-aging, hydrating, repair and protection, and many other benefits.


Peptide Night Cream Drmtlgy is a luxurious cream which promises to hydrate and eliminate dull skin, lift and firm, repair and protect, and smooth lines and wrinkles while you sleep at night. This pure organic formula comes highly recommended by dermatologists all over the world, and is also dermatologist-developed.

After reading through the Peptide Night Cream reviews, I immediately went out and bought some myself. The users loved the enriching and anti-aging properties of this formula, and many said they loved waking up to a smooth, soft, vibrant complexion.

Peptide Night Cream includes 100% safe, organic ingredients, with no parabens, sulfates, fragrance, or other additives or agents that could cause a skin reaction. I would highly recommend this cream as both a customer and a reviewer, and I certainly give it 5 stars.

Where To Find It?

You can BUY it directly from the Official Website

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Peptide Night Cream

Drmtlgy Peptide Night Cream Review: Wake Up With Refreshed, Youthful-Looking Skin

Average Customer Rating

out of 5

Review this Product

Leave a review and share your experience with others.

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  1. Peter K.

    For Men Too
    Lately, my skin has been really dry, so I researched Drmtlgy Peptide Night Cream seemed to be what I needed. I am very happy with the results and the consistency and moisture levels of my complexion. Good product!
  2. Jess

    Excellent Cream
    I got this on my sister’s recommendation, and I am so pleased with it. Sadly, I was almost getting used to the dryness of my skin, but with this formula, I am looking younger and fresher every day, and people are noticing! Love it!
  3. Grace C.

    Found This Amazing Night Cream
    Best night cream ever! In the morning your skin will be moisturized, radiant, and ready for the new day. What I really can’t believe about this formula is how affordable it is for the quality – in line with all of the skin care from the Drmtlgy line. This peptide cream is worth every penny, and I will never stop using it! – Grace C.
  4. Ritu V.

    Affordable and it Really Works!
    I love this peptide night cream! I was getting really dry skin at my age, not to mention wrinkles around my eyes that I wanted to get rid of ASAP. Every morning, I wake up with downright drinkable skin, and those lines are fading fast. Thank you! – Ritu V.

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Peptide Night Cream
Drmtlgy LLC
Ceramides, Vitamin E, Shea Butter, Peptides

11 sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

1. An Insight into the Changes in Skin Texture and Properties following Dietary Intervention with a Nutricosmeceutical Containing a Blend of Collagen Bioactive Peptides and Antioxidants: https://www.karger.com/Article/Fulltext/464470
2. Antioxidants and Skin Care: The Essentials: https://journals.lww.com/plasreconsurg/Citation/2010/01000/Antioxidants_and_Skin_Care__The_Essentials.45.aspx
3. Ceramides and Skin Function: The Essentials: https://www.researchgate.net/publication/10929073_Ceramides_and_Skin_Function
4. The role of vitamin E in normal and damaged skin: https://pubmed.ncbi.nlm.nih.gov/7633944/
5. The Use of Shea Butter as an Emollient for Eczema: https://www.jacionline.org/article/S0091-6749(08)03527-6/fulltext
6. Topical Peptide Treatments with Effective Anti-Aging Results: https://www.researchgate.net/publication/317120448_Topical_Peptide_Treatments_with_Effective_Anti-Aging_Results
7. Cosmeceuticals: Peptides, Proteins, And Growth Factors: https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/shea-butter 8. Ceramides And Skin Function: https://pubmed.ncbi.nlm.nih.gov/12553851/ 9. Shea Butter: https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/shea-butter 10. Role Of Topical Peptides In Preventing Or Treating Aged Skin: https://pubmed.ncbi.nlm.nih.gov/19570099/ 11. Epidermal Surface Lipids: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835894/

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

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