In This Review
Overview of CircO2
Let’s talk about something you hardly think about – the silent symphony happening inside us every moment. Yes, our bodies are a marvel, humming with activity, yet sometimes, this harmony faces hitches. Imagine your energy levels dipping, your vitality is not what it used to be.
It’s not just ‘getting older’; it could be something crucial yet often overlooked—our body’s nitric oxide levels.
Now, before you jump to conclusions or worry sets in, know that science always seeks to bridge such gaps. In strides, CircO2, a supplement crafted not just as a band-aid solution but as support for your body’s natural rhythms, could help. It’s about enhancing what’s already there, ensuring your internal orchestra plays on, beautifully and energetically.
Let’s explore how CircO2 might just be the tune-up you didn’t know you needed.
What is CircO2?
CircO2 is a supplement developed to address the decline in nitric oxide production as we age, which plays a pivotal role in our vascular health and overall well-being.
Nitric oxide signals the endothelial cells lining our blood vessels to relax, improving blood flow and nutrient delivery throughout the body. However, with aging, our body’s ability to produce this vital molecule diminishes[1].
The formula for CircO2 combines ingredients known to support the production of nitric oxide. Designed for efficient absorption, CircO2 dissolves in the mouth to maximize the engagement with oral bacteria essential in the conversion process, ensuring effective utilization of its ingredients.
In our experience, CircO2 can significantly elevate nitric oxide levels, leading to improved vitality, better sleep quality, reduced joint pain, enhanced cognitive function, and an overall uplift in well-being.
How Does CircO2 Rate?
Brand Highlights
- The brainchild of Stephen J., a scientist from MIT.
- Offers discounts on purchases.
- Products come with a 100% money-back guarantee.
- Offers free shipping for select packages.
- Products manufactured in the USA.
Key Ingredients
- Beetroot Powder
- L-Citrulline
- Hawthorn
- Vitamin B12
- Vitamin C
Pros
- Backed by overwhelmingly positive user reviews.
- Boasts the use of 100% natural ingredients.
- Manufactured in an FDA-approved facility.
Cons
- Only available online, which might prove inconveniencing.
- Results may vary from person to person.
Who Is The Manufacturer of CircO2?
Advanced Bionutritionals – the manufacturer of CircO2 – is a leader in the nutraceutical industry, committed to providing high-quality supplements for a wide range of health needs. Their partnership with leading suppliers ensures each product comes packed with fresh, premium ingredients, adhering to stringent manufacturing guidelines.
The brand stands out for its dedication to excellence and the expertise of its team, making it a trusted name in natural health solutions.
The company’s vision is brought to life by three experts: Dr. Frank Shallenberger, Janet Zand, O.M.D., L.Ac, and Steve Kroening, ND. Their combined experience spans integrative medicine, herbal formulation, and health journalism. The result? A holistic approach to wellness that blends scientific research with natural remedies.
How Does CircO2 Work?
CircO2 targets the core of vascular health by focusing on the endothelium, the inner lining of our blood vessels. This layer is vital for regulating blood flow and ensuring that oxygen and nutrients reach every part of our body. However, with age, its functionality can diminish, slowing down blood flow and affecting overall health[2].
The supplement works by naturally enhancing the production of nitric oxide, a key molecule responsible for signaling the endothelium to relax. When the endothelium relaxes, it allows blood vessels to widen, facilitating better blood circulation. This process is crucial because improved blood flow means more oxygen and nutrients delivered throughout the body[3].
CircO2 aims to tackle issues stemming from reduced blood flow by optimizing nitric oxide levels and supporting endothelial function. The intended result is a cascade of potential health benefits, including but not limited to, enhanced energy levels, better sleep quality, diminished joint pain, and sharper cognitive functions.
The effectiveness of CircO2 hinges on consistent use, as maintaining optimal nitric oxide levels and endothelial health requires continuous support. The supplement’s approach is grounded in understanding the foundational role of endothelium and nitric oxide in vascular health.
CircO2 Ingredients – Are they Safe & Effective?
Here’s a closer look at what makes these components stand out:

Beetroot Powder
This vibrant root vegetable is not just for salads; its powder form is a powerhouse in CircO2. Rich in nitrates, beetroot powder is converted by the body into nitric oxide, a molecule that relaxes and widens blood vessels. This process can boost blood flow and oxygen delivery, potentially enhancing energy levels and exercise performance. A 2016 study notes[4];
The nitrate (NO3(-)) present in beetroot juice (BJ) has been studied for its effect on the cardiovascular system by converting to nitric oxide (NO). –Diego dos Santos Baião, et al.
Beyond its cardiovascular perks, beetroot powder acts as a potent antioxidant, combating oxidative stress and inflammation, while also supporting brain health and cognitive function.

L-Citrulline
This amino acid is a key player in the body’s production of nitric oxide. Unlike L-arginine, another amino acid used in many supplements, L-citrulline is more efficiently absorbed and converted into L-arginine in the kidneys, boosting nitric oxide levels more effectively. While investigating this, a 2018 study notes,
l-citrulline is not acted on by arginase enzyme or first-pass extraction but is converted to l-arginine by argininosuccinate lyase in the kidneys. Increased circulating l-arginine serves as a substrate for the eNOS to produce nitric oxide (NO) and increase smooth muscle vasodilation. –Timothy D. Allerton, et al.
Its benefits extend to improved exercise performance, reduced muscle fatigue, and better blood circulation, making it a critical component of CircO2[5].

Hawthorn
With a history rooted in traditional medicine, hawthorn is revered for its heart and circulatory health benefits. The shrub’s bioactive compounds shield endothelial cells, which are crucial for healthy blood vessel function.
Hawthorn’s antioxidant properties further reduce oxidative stress and inflammation, and it has been linked to lower blood pressure, improved cholesterol levels, and support for healthy aging, claiming its rightful place in CircO2’s formula[6].

Vitamin B12
An essential nutrient, vitamin B12 is vital for nerve function, red blood cell production, and maintaining brain health[7].
A deficiency in this vitamin can lead to cognitive issues and fatigue. In CircO2, vitamin B12 plays a dual role—it not only supports brain and memory health but also aids in nitric oxide production, contributing to the supplement’s effectiveness.

Vitamin C
Known primarily for its immune-boosting capabilities, vitamin C is also a strong antioxidant that combats oxidative stress, a factor in endothelial dysfunction.
Its inclusion in CircO2 is strategic; Vitamin C aids in nitric oxide production, particularly in older individuals, helping to maintain endothelial health and promote healthy blood flow, thus supporting cardiovascular wellness[8].
Verdict: Together, these key ingredients synergize in CircO2, aiming to enhance nitric oxide production, protect the endothelium, and foster overall health.
Benefits of CircO2
Improved Blood Pressure: CircO2 is designed to support the natural maintenance of healthy blood pressure levels. By enhancing nitric oxide production, it helps to relax and dilate blood vessels, ensuring smoother blood flow and reducing strain on the heart.
Increased Energy Levels: The supplement aids in improving circulation and oxygen delivery to various parts of the body. Better oxygenation of tissues leads to increased energy and stamina, so you engage more actively in daily activities and exercise.
Enhanced Sleep Quality: Good circulation also plays a role in regulating the body’s natural sleep cycles. By promoting relaxation and reducing discomforts that might interfere with sleep, CircO2 helps users enjoy more restful nights.
Joint Health Support: CircO2 contributes to reducing inflammation around joints, which can alleviate pain and improve mobility. This is particularly beneficial for those experiencing stiffness or discomfort due to conditions like arthritis.
Sharper Cognitive Functions: Improved blood flow means better oxygen and nutrient delivery to the brain, which can enhance cognitive functions such as memory, focus, and problem-solving skills.
Cardiovascular Health: The flexibility of arteries is crucial for preventing cardiovascular diseases. CircO2 helps to maintain artery health, reducing the risk of blockages and supporting efficient blood circulation, thereby nurturing a strong and healthy heart.
Safety
Natural Ingredients: CircO2 is typically formulated with natural ingredients known for their safety and effectiveness in boosting nitric oxide levels.
Quality Control: The manufacturers of CircO2 follow strict quality control standards to ensure the safety and purity of their products.
Clinical Research: Many of the ingredients in CircO2 have been studied for their safety and health benefits, providing a level of assurance regarding their use.
Side Effects
Digestive Issues: Some users may experience mild digestive discomfort, such as nausea or diarrhea, particularly when first starting the supplement. Taking it with food can help mitigate these effects.
Headaches: Increased nitric oxide levels can sometimes lead to headaches in some individuals due to vasodilation effects.
Allergic Reactions: Although rare, some individuals may have allergic reactions to specific components in CircO2. It is essential to review the ingredient list and consult a healthcare provider if you have known allergies.
Interaction with Medications: CircO2 may interact with certain medications, especially those that affect blood pressure or blood flow. It is crucial to consult a healthcare provider before starting any new supplement if you are on medication.
How Effective is Circo2?
Circo2 is designed to improve cardiovascular health and enhance exercise performance, primarily through its key ingredient, L-citrulline. This amino acid boosts nitric oxide levels in the body, which supports better blood flow, nutrient delivery, and endurance. Research backs this claim, showing that L-citrulline can enhance aerobic capacity and recovery times, particularly during intense physical activity.
Customer reviews highlight improvements in energy, stamina, and circulation, with many users reporting better workout performance and faster recovery. The addition of beetroot extract, a natural source of nitrates, further enhances the product’s ability to increase nitric oxide levels and support overall cardiovascular health.
While individual results can vary, the combination of these ingredients has a solid foundation in promoting both performance and heart health. For best results, it’s recommended to use Circo2 as part of a balanced lifestyle with regular exercise and a healthy diet.
CircO2 Review – FAQs
Q: Is CircO2 suitable for all ages?
A: CircO2 is designed for adult use, particularly beneficial for those noticing the effects of aging. However, if you have concerns, consulting a healthcare provider is advisable.
Q: Can CircO2 interact with the medications I’m currently taking?
A: While CircO2 contains safe, natural ingredients, it’s important to discuss with your healthcare provider if you’re on medication, to avoid potential interactions.
Q: How do I know if CircO2 is working for me?
A: Monitor changes in your energy levels, sleep quality, and overall well-being. Improvements in these areas can indicate its effectiveness.
Q: How to use CircO2?
A: Using CircO2 comes in lozenge form, intended to dissolve in your mouth. This unique delivery method ensures the mix of the active ingredients with oral bacteria, jumpstarting nitric oxide production efficiently.
For those new to CircO2, it’s recommended to start with two lozenges a day during the initial one to two weeks, adjusting the dosage thereafter to suit personalized needs and experiences.
Q: Can CircO2 aid in recovery after exercise?
A: Yes, by improving blood flow and oxygen delivery, CircO2 can support quicker recovery and reduce muscle soreness after physical activity.
Q: How does CircO2 support brain health?
A: Improved blood flow means better oxygen and nutrient delivery to the brain, supporting cognitive functions and mental clarity.
Q: How long should I continue taking CircO2?
A: CircO2 is designed for ongoing use to maintain its benefits. Discuss long-term use with your healthcare provider.
Q: Can CircO2 help manage stress?
A: CircO2 may not directly relieve stress, its promotion of improved energy and well-being can indirectly contribute to managing stress levels.
Q: How much does CircO2 cost?
A: The current price of CircO2 on the official website is;
-
1 box for $49.95
3 boxes for $134.85 + Free Shipping
6 boxes for $249.00 + Free Shipping
What Do the CircO2 Customer Reviews Say?
CircO2 has a 4.2 average rating based on 1355 Reviews on its official website. Here are the standout reviews we singled out;
I have to say that after letting this good tasting tab melt in my tongue, within about 10 minutes I can feel the effects. I have more energy and feel very alert. –Michael H. Treadwell, NY(Official Website)
I take it every day … you can begin to see results immediately. –Robert J. Austin, TX(Official Website)
Energy is all the way UP … I felt the difference after 15 minutes of taking it. –Tifiro C. Riverview, FL(Official Website)
I’m 77 years old and I’ve been taking CirCO2 for just over a month now and have so much more energy. I’m a home builder and remodeler and where I used to work 4 to 5 hours a day on a project I’m now working 6 to 7 hours each day and still raring to go. –Mike
I’ve been using Circ02 for about 3 weeks and I’ve noticed a difference in my joints which are feeling a lot more flexible and not so stiff. I was able to go for a run the other day and I haven’t been able to run for 2 to 3 years because of swelling and stiffness in my right knee. –Trevor
CircO2 Review – Conclusion
CircO2 offers a promising approach to enhancing wellness through improved nitric oxide production. Its benefits, touching on energy, blood flow, and overall vitality, make it a noteworthy contender for those looking to boost their health naturally.
Tailored for adults and backed by positive reviews, its simple yet effective lozenge form sets it apart. CircO2’s commitment to quality and satisfaction through its refund policy reflects its confidence in delivering value. Ultimately, for those exploring ways to support their health, CircO2 is worth the shot.
Where To Find It?
You can BUY it directly from the Official Website
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