Biofreeze Review – Does Biofreeze Help Reduce Inflammation Effectively?

Biofreeze is a topical analgesic designed to relieve minor to moderate joint discomfort. It can also be used to treat muscular aches and pains, as well as arthritis-related discomfort.

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In This Review

What is Biofreeze?

Joint pain and inflammation are commonly caused by damaged tissues brought by friction, stress, or aging.

This process is inevitable because as people age, the joint surfaces become prone to damage and the body is no longer capable of rapidly repairing the damaged tissues. Since more and more people are suffering from joint pain, different products are also manufactured to answer this rising problem.

Biofreeze is one of those topical joint pain products that aim to help people suffering from joint pain and discomfort.

Biofreeze is a topical analgesic that is manufactured for mild to moderate joint pains. It can also be used to relieve muscle soreness and even discomfort associated with arthritis.

Biofreeze actually comes in the spray, singles, roll-on, and gel preparations so the consumer has the freedom to choose how they want the product applied. While other topical analgesics contain steroid and narcotic components which impose serious side effects.

Biofreeze contains the most basic ingredient which is natural and proven to be effective in reducing pain.

How Does It Rate?

Overall Rating: 3.5

Value For Cost

3.5/5Value For Cost
Return Policy

3.5/5Return Policy


Brand Highlights

  • The company that originally launched Biofreeze was Performance Health, Inc. However, in the year 2006, the company was acquired by the Hygenic Corporation.
  • Today, Hygenic Corporation is the legal manufacturer of Biofreeze which is also responsible for the continuous research and improvement of the product. Their office is located in Akron, Ohio.

Key Ingredients

  • Menthol


  • May reduce mild to moderate joint pain and discomfort.
  • It could relieve muscle soreness.
  • Since it is a topical analgesic, the benefit of pain relief is targeted to the affected area specifically.
  • It might produce fast and long lasting effect.


  • It has a menthol scent that is quite noticeable.

Which Are The Best Selling Biofreeze Products?

#1 Biofreeze Spary

Biofreeze Spary
Biofreeze Spary

Soothing, Pain Relief

Key Ingredients: Menthol

Price: $21.96

What It Does: Our 360° applicator gets those hard-to-reach places, like the middle of the back or neck and other lower extremities, so you can always rise to every challenge.

#2 Biofreeze Gel

Biofreeze Gel
Biofreeze Gel

Back Pain Relief
Key Ingredients: Menthol

Price: $14.69

What It Does: Apply Gel to the larger muscle areas that might require a more hands-on approach and push your training even further.

#3 Biofreeze Roll On

Biofreeze Roll On
Biofreeze Roll On

Fast Acting & Long Lasting
Key Ingredients: Menthol

Price: $9.99

What It Does: Grab a Roll-On for a mess free application with a roller ball that applies easily to cool the pain.

How Does Biofreeze Work?

Biofreeze basically works by following the mechanism called gate control theory wherein the menthol contained in Biofreeze serves as a counterirritant to divert attention away from the pain.

According to research published in the BMJ regarding the gate control theory, the pain is caused by stimulation of 2 types of afferent nerve fibres[1].

When Biofreeze is applied to the affected area, menthol will stimulate the thermoreceptors in the skin causing a cooling sensation, this will then stimulate the non-nociceptive nerve fibers (nerve fibers that do not cause pain). The stimulation of the non-nociceptive nerve fibers will serve as the counterirritant mechanism which causes the reduction of pain sensation on the affected area.

Biofreeze Ingredients – Are they Safe & Effective?

The primary ingredient in Biofreeze is menthol which is very popular in reducing joint and muscle pain.

According to EurekAlert, menthol has been shown to possess analgesic properties thereby reducing the sensation of pain[2]. It is mostly used in topical analgesics because when menthol is absorbed through the skin, it attaches to kappa opioid receptors thus producing a numbing effect.

It also causes vasodilation thereby improving blood flow and enhancing lymphatic drainage which helps in reducing inflammation in the affected area. Menthol is also a popular counterirritant because it stimulates the thermoreceptors in the skin which produces the cooling sensation when it is applied[3]. This cool sensation serves as a counterirritant thereby blocking the nerve impulses that cause throbbing pain.

Alternatives to Biofreeze

Biofreeze Questions and Answers

Q: How Should You Use Biofreeze?

A: Adults and children 2 years of age and older should apply on to the affected areas not more than 4 times daily. Consult a physician before using it on children under 2 years.

When using this product: Avoid contact with the eyes or mucous membranes– Do not apply to wounds or damaged skin.

Q: Can I use Biofreeze Foot therapy cream on my back?

A: Temporary relief from minor aches and pains of sore muscles and joints associated with: arthritis, backache, strains, sprains

Warnings: For external use only- Ask a doctor before use if you have: Sensitive skin

Q: How Much is Biofreeze?

A: The product is available on the manufacturer’s official website and various online retail stores at a price of $14.99.

Q: What is Biofreeze Return Policy?

A: Biofreeze products are not backed by any refund or money back guarantee policy.

Q: Does Biofreeze Offer a Free Trial?

A: There are no free trials or any offers available on Biofreeze.

Q: How large of an area on the body does a patch work on?

A: The Biofreeze patch is created with USP grade ingredients delivers targeted, mess-free application and penetrates swiftly for up to 8 hours of pain relief to body parts such as the back, neck, shoulder, knee, wrist, and foot.

Q: What are the Precautions When Using This Supplement?

A: This product is for external use only.

  • Apply the product as directed by the manufacturer.
  • Wash your hands after using Biofreeze to prevent the transfer of the product to the eyes. If it accidentally gets into your eyes, immediately wash it with a copious amount of water.
  • Keep out of children’s reach.
  • Do not apply tight bandage around the area where Biofreeze is applied.
  • Do not apply heating pads to the area where Biofreeze was applied because the numbing effect of the product might cause burn injuries.
  • Do not apply to broken, irritated, or wounded skin.
  • If you are currently applying other topical products, consult your doctor prior to using Biofreeze.

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Q: How often should I use Biofreeze on a painful hip when walking?

A: Biofreeze comes with a clinically recommended seal, and it’s a longtime trusted brand for joint pain relief. This medication is for use on the skin only. Apply to the affected area no more than 3 to 4 times a day. If you are using the cream, gel, or liquid, rub it gently and thoroughly. Some liquid forms of this medication should be shaken before use.

What Kind of Reviews are Out there for Biofreeze?

Most customers who used the product were satisfied with the Biofreeze benefits. It is effectively reduced their joint and muscle pain without the worry of experiencing serious side effects.

People also liked that Biofreeze comes in various preparations wherein all are very handy especially the Biofreeze singles thus they can experience pain relief anywhere and anytime they want. The consumers also noted the immediate and long-lasting pain relief that is provided as compared to other topical analgesics.

Biofreeze Review – Final Verdict

Biofreeze is a good topical joint pain relief product to consider if you are looking for immediate and effective relief for joint pain and discomfort. The mechanism behind the effectiveness of Biofreeze is simple but is proven to be effective through years of research and clinical trials.

Bones are connected by joints, which allow us to move with ease. Joint damage can cause pain preventing you from doing the things you once loved. Topical joint relief products tend to work more quickly, helping to relieve pain directly in the affected area compared to products taken orally. A topical joint pain relief product should be evaluated on its: potential to block the transportation of pain signals, potential to act as a counterirritant to reduce soreness and Quality of Ingredients* backed by clinical research.

Below you’ll find some of the most effective topical joint pain products on the market today, in our opinion.

Our Top Joint Pain Relief Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned joint pain relief gels, gummies, and creams based on the available research:

Well Care Botanicals | Hemp Extract Pain Relief Cream
Remove Inflammation & Soreness*Gold Star Evidence
Pain-Relieving Benefits*Gold Star Evidence
Supports Cartilage and Tissue*Gold Star Evidence
Rapid Pain Relief*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Barker Wellness | Cannabinoid-Infused Products
Nurtures Body & Mind*Gold Star Evidence
Targets Sleep & Focus*Strong Evidence
Wide Range of Products*Gold Star Evidence
Natural and Organic*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Aspercreme | Best Pain Relief Cream
Non-Greasy Cream*Gold Star Evidence
Relieves Arthritis Pain*Strong Evidence
Supports Joint & Muscles*Strong Evidence
Fast-Acting Formula*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Biofreeze

Biofreeze Review – Does Biofreeze Help Reduce Inflammation Effectively?

Customer Reviews & Ratings

3.4 out of 5

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  1. Delmar

    Get the one that rolls on like deodorant that is in our local grocery store.
    The roll-on is much easier to use than gels or others that rub on. It only goes on the part of the body where you want it – not on your hands.
  2. Ralph Griffith

    Eye balls on fire!
    If I use spray, the mist gets in my eyes, but it does the job in the sprayed area. Tell me how to solve it, and I will give it a 5 Star.

    I would not recommend it for many reasons – if it were free I would run away!

  3. Ralph Griffith

    Anyway, you spray, up down sideways the mist gets to your eyes and burns - flushing with warm water seemed to help, bothering me after 3 hours!
    You should furnish eye coverings with the product! And make a trigger type dispenser – people with arthritis in all fingers cannot push down on the present button – once you get the product to the sore spots does work ok – will never repurchase this product or any product you manufacture!
  4. Zelisa Lane

    Bio Freeze is an excellent product.
    Let me tell you something! This Bio Freeze has done the trick. I am usually very active, never had any problems. But, when I turned 50 my back and muscles started aching like crazy. I started having muscle spasms and picked up weight. I am mobile again and working out. Bio Freeze is that and some. Thank You. I wish I would have discovered this two weeks ago. I went through some unnecessary pain.
    50 and counting
  5. L Bee

    Cream good, gel not working
    I have been using the Biofreeze CREAM for years and it works! I would give it 5 stars. I went to get some today at Walmart and they had GEL but no cream so I got it. I can’t believe the difference. It doesn’t get deep like the cream. I’m really disappointed. The Biofreeze gel is a complete waste of money. Can you rate a product 0 stars?
  6. Mary Louise Kelley

    Love product but company but the follow-up procedure is not as expected
    I ordered through on January 14 paid $61.97 for 32 oz colorless professional gel with pump and still have not received my product. Has gone through the bank on January 15. Order number 000005420. I have emailed 5 times called 6 times and left messages. Love product but company is the worst. Still no refund.
  7. Ruth Conger

    Bio-freeze worked when nothing else did! I had purchased the box with individual packets. So very thankful!
    I am 89 years old. I am very bent forward in posture thus causing a deep hidden place around my waist on my left side. This past weekend it became so painful like someone sticking me with pins. I could do nothing for relief. I tried all kinds of soothing creams, however nothing worked. My daughter told me there was some Biofreeze in my first aid cabinet. ‘Let’s try it’ was my reply. It was like a miracle! I had become so upset because none of the rather expensive products were working. Biofreeze worked & I finally got some needed rest. THANK YOU!
  8. Nancyann Schiappa

    Looking for unscented topical cream
    I take Xarelto. I need an unscented topical cream for my arthritic knees. I don’t want it to interfere with this blood thinner. Which one is good. I am 92 thank you!
  9. julieanna Anna KOLANKOWSKI


    Biofreeze spray, does not spray.
    Biofreeze spray does not spray, streams. Tried everything. Going back to Walgreen’s spray. Has worked every time. Usually, on sale, as well.

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Bio freeze Ques and Ans

  • Q: Can you wear compression socks over ankles treated with biofreeze

    A: It is generally not recommended to wear compression socks over ankles treated with Biofreeze joint pain relief. This is because Biofreeze can cause the skin to become cold and numb, and compression socks can further constrict blood flow to the area. This can lead to skin irritation, pain, and other problems.

    If you are experiencing pain or inflammation in your ankles, it is best to apply Biofreeze and then wait for the area to dry before putting on compression socks. You can also try wearing loose-fitting socks or compression sleeves instead of compression socks.

  • Q: Will Biofreeze help stomach nerve pain and burning?

    A: Biofreeze is a topical pain relief gel that contains menthol, which can provide a cooling sensation and temporarily relieve minor aches and pains of muscles and joints. However, it is not specifically formulated to treat stomach nerve pain and burning, and may not be effective for this type of pain.

  • Q: Is it safe to use Bio freeze professional if having knee surgery in 7 days and when should I discontinue it ?

    A: No, It only helps to relieve pain, swelling, and joint stiffness while also improving your ability to move and flex the joint. If you are having knee surgery for a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to relieve your pain.

    If you have experienced this reaction in the past, stop taking Biofreeze.

    1. Acute arthritis 2. Rheumatologic diseases 3. Infective arthritis 4. Traumatic arthritis 5. Knee replacement surgery history Patients who have received repeated corticosteroid injections (Greater than 2 injections)

  • Q: How do you make the Biofreeze spray come out -- I removed the outer plastic & it won't spray?

    A: All you just need to do is just a little bit of a spray press. And hold firmly to activate the sprayer.

  • Q: What's the difference between Bio Freeze professional and Bio Freeze pain relief?

    A: Biofreeze Professional is the product the PT or the chiropractor use they last longer and it's more strength to it versus the regular Biofreeze.

  • Q: Is Biofreeze safe for animals? My cat loves the scent and tries to lick the area.

    A: ANDREA M. BRODIE, DVM Veterinarian says, "You can use all those provided your cat does not lick the cream or gel. As long as you do not let your cat lick your skin after applying the medication, it is safe for your kitty. There are no 100% safe pain ointments or gels that can also be ingested by your cat without safety concerns."

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Performance Health, Inc.

3 sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] The gate control theory of pain :
[2] Adding menthol to topical creams for osteoarthritis provides significant pain relief :
[3] What is menthol? :

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

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