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Experiencing issues with your joints can be cause for a lot of pain and discomfort as a person. It dramatically affects the ease to conduct usual daily activities such as walking, ruing, climbing or stretching.

Many people consider taking joint relief supplements that can help reduce joint discomfort t and pain. SAM-e Joint is a supplement designed for those seeking relief of pain or discomfort in the joints.

What is SAM-e Joint?

SAM-e Joint is a joint supplement used for the ease of pain and discomfort in the joints. The supplement is designed to help reduce inflammation cases while increasing ease of mobility.

With the use of the supplement, one is supposed to have a production and repair of cartilage. It helps with the increase of flexibility in the joints during movement. The supplement also provides liver detoxification and improves mood and brain function.

Who is the Manufacturer of SAM-e Joint?

SAM-e Joint

The company behind the development of CHD SAM-e Joint supplement is known as the Jarrow Formula. The manufacturers claim the product provides joint, liver and brain health support. They argue that the supplement contains all-natural ingredients that work towards the relief of joint pain.

The supplement is said to be manufactured under low humidity and low temperature. They claim that the supplement is enteric-coated to maintain it as a biologically active product and is individually blister-packed.

SAM-e Joint Ingredients – Are they Safe & Effective?

525mg of Glucosamine HCL

  • It is a synthesized aminosaccharide. It is an element of joint and intestinal tissue that is part of the synovial fluid production used in the lubrication of joints.

200mg of S-Adenosyl Methionine (from 400mg of SAM-e tosylate disulfate)

  • It is found in living cells. It is a metabolite of methionine which is an essential amino acid. It is a chiral molecule that is in two forms; (S, S) SAM-e and (R, S) SAMe.
  • It is made through natural microbiological fermentation after which it is specially processed without the use of chemical solvents to preserve the 68-80% of (S-S) SAMe.
    The SAM-e Joint supplement has the highest concentration of active S, S Form (68-80% SAM-e).

Other ingredients include; Cellulose, glyceryl behenate, oleic acid, titanium dioxide, stearic acid, silicon dioxide, dextrin, sodium citrate, dextrose, magnesium stearate, and medium chain triglycerides.

How Does SAM-e Joint Work?

The SAM-e Joint supplement works in various ways. It helps in the production of connective tissue through transulfuration for the maintenance of joint strength. It is where vital components of connective tissue such as glucosamine and chondroitin get sulfated by metabolites of SAMe to produce sulfated glycosaminoglycans (GAGAS).

It produces methylation reactions that involve in the synthesis of neurotransmitters such as L-DOPA & Dopamine, and related hormones such epinephrine, phosphatidylcholine, and serotonin to boost brain metabolism.

The metabolism of SAMe helps in the synthesis of glutathione (GSH) and glutathione-dependent enzymes that are part of the body’s endogenous antioxidant network which is vital for promoting liver function such as phase II detoxification.

What are the Advantages of SAM-e Joint?

  • It may offer relief and strength of joints
  • It provides flexibility and mobility
  • May promote better liver function
  • May help improve brain function.

What are the Disadvantages of SAM-e Joint?

  • The SAM-e Joint supplement contains only two ingredients
  • The supplement lacks on the many natural ingredients known for joint relief


How Much Does SAM-e Joint Cost?

SAM-e Joint supplement is available online at about $31.92. Prices of shipment may as well be incurred depending on your address.

SAM-e Joint Joint– Is It Safe?

The SAM-e Joint is said to be made from natural ingredients and thus safe for use. It is, however, recommended that one does not exceed the recommended dosage of one tablet, once or twice a day. To avoid unwanted side effects.

The supplement is not to be used by pregnant or nursing mothers, persons with Parkinson’s disease, manic depression, or bipolar disorder. Persons under prescribed medications such as anti-depressants should ensure they first consult with a physician before use.

What Kind of Reviews are Out there for SAM-e Joint?

The supplement is widely available online, but the reviews featuring it are scarce. A review mentioned the product to be of high quality in supporting their mood and joint comfort. Some consumers claimed that the supplement did not deliver quite to their expectations.

SAM-e Joint Review – Final Verdict

SAM-e Joint supplement is a product used mainly for supporting joint relief from pain and discomfort. It enables its users to achieve better mobility and flexibility. The supplement can still be useful for liver detoxification and brain metabolism.

The supplement, however, has just two ingredients in its formulation. There are various ingredients well known in joint support that are not present in the product. Moreover, many other products are offering similar pros to those of SAM-e Joint supplement.

Healthy joints allow us to move with ease. Joint damage can cause pain preventing you from doing the things you once loved. From aging to untreated sports injuries – many conditions lead to joint pain. A quality joint product may help reduce inflammation, repair existing tissue damage, and promote stronger joints, lessening susceptibility to future degeneration.

Below you’ll find some of the most effective joint pain supplements on the market today, in our opinion.

Our Top Joint Pain Relief Choices
Projoint Plus - 5% OFF Today
Projoint Plus
Fight Joint Pain and Inflammation*
Enhance Joint Mobility*
Prevent Recurring Damage*
Long Lasting Results*
Quality of Ingredients*
Joint N-11
Joint N-11
Fight Joint Pain and Inflammation*
Enhance Joint Mobility*
Prevent Recurring Damage*
Long Lasting Results*
Quality of Ingredients*
Fight Joint Pain and Inflammation*
Enhance Joint Mobility*
Prevent Recurring Damage*
Long Lasting Results*
Quality of Ingredients*

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer.

Customer Reviews for SAM-e Joint

SAM-e Joint Reviews

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  • Then all you have to do is click the Browse button and search for your receipt picture file. You can also drag and drop the file into the provided field.

If you are still not able to upload your proof of purchase, please contact us for further assistance (take a moment to look over the sample bill below).


**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

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