In This Review
Overview
As we grow older, we begin to lose our cognitive abilities, and our age starts to show in our ability to perform mentally tasking activities.
Several supplements on the market promise to help improve cognition and slow the aging process of brain cells. Most of them don’t work, and some have too many side effects that they nullify whatever cognitive improvements they may offer.
Vitaae is a brain-boosting supplement that has gained attention among supplement users and the media for its claims to support brain health effectively without any significant side effects. The question remains, “Does Vitale perform as well as promised, or is it just another well-marketed supplement that doesn’t work?”
In the comprehensive review, we will explore the specifications, ingredients, scientific claims and research, user experiences, potential side effects, pricing, and viability of Vitaae to provide an extensive analysis of this supplement’s effectiveness and safety.
What is Vitaae?
Vitaae is a supplement that claims to harness the power of specific, doctor-formulated proprietary ingredients to help improve cognitive function and brain health while relieving throat phlegm, coughing, and brain fog.
Stanford Medicine Magazine discusses the vital connection between the brain and Phlegm production in the body.[1] Vitaae claims to help reduce the discomfort caused by excess phlegm production by “turning the brain fire off.”
According to the official website that manufactures Vitaae, SANESolution, Vitaae can provide its users with improved mental clarity, less phlegm, deeper concentration, and better moods. It’s like one of the many memory pills on the market but with other extra benefits.
How Does It Rate?
Brand Highlights
- Products are Manufactured in the USA
- Led by a Former Microsoft Employee
- Claims a 3-5 days fast shipping
- Claims Every Product is Third-party Tested for Purity
- 1 Year 100% Money Back Guarantee
Key Ingredients
- Citicoline Sodium (100 mg)– Vitamin D (as cholecalciferol) – 125 mcg (5,000 IU)
- Quartrefolic (Proprietary form of folate that SANESolution claims to be more bioavailable) – 670 mcg DFE
- Vitaalmind Proprietary Blend (Packed with Omega-3 fatty acid (EPA/DHA)) – 1560 mg
- HydroQsorb (Proprietary Coenzyme Q-10 Cyclodextrin Complex) – 50 mg
Pros
- The ingredients contained in Vitaae are less likely to cause side effects at the included dosage
- All of the active ingredients in Vitaae are well-studied and are considered safe for the average consumer
- Some customers claim that the drug works as advertised
- Many customers attest to its effectiveness in clearing up phlegm
- Customer reviews say the product also helps with weight loss
- Vitaae is gluten-free
Cons
- There is no evidence that the drug was clinically tested. Only the ingredients used have been clinically tested.
- The money-back-guarantee program is not usually honored based on customer reviews
- The supplement was changed from capsules to hard-to-swallow tablets according to customer reviews
- Needs to be taken daily to work, and the problem returns once you stop taking it
- It is hard for users to quantify an improvement in memory objectively
- Many people consider it expensive
About the Brand
SANE MD, registered as SANESolution, is the company that manufactures and distributes Vitaae and other supplements that aim to improve various aspects of their user’s well-being. According to the company’s website, SANESolution was founded in 2014, even though its profile on Better Business Bureau states that it was started in 2008 and incorporated in 2013.[2]
SANESolution offers wellness products and services that they claim have been clinically tested and proven to help the intended consumers of their products and services.
It is important to note that one thing many of SANESolution’s customers have complained about the most has been their failure to honor their return policy. SANESolution advertises a one-year money-back guarantee on Vitaae, but many customers claim that they do not usually get their money back when the products don’t work as expected.
Vitaae is one of SANESolution’s flagship products, and according to the company website, every bottle is manufactured in the United States to ensure the highest quality standards possible. SANESolution is committed to providing health-promoting solutions for its valued clients and customers.
How Does Vitaae Work?
According to SANESolution’s website, Vitaae helps clear phlegm and boost the cognitive functions of whoever uses the supplement. SANESolution claims that the difference between “leaky brain” and “lost memories” should be more noticeable in older people. Research shows that symptoms like brain fog, memory loss, and lack of concentration is usually caused by the inflammation of molecules in the brain.[3]
Vitaae is a supplement designed to help improve your concentration and general cognitive performance by reducing brain inflammation using ingredients that help your immune system heal faster. Vitaae claims to also improve your mood, help with depression, and memory loss.
Vitaae also helps to relieve throat phlegm and coughing using a blend of proprietary ingredients like Quatrefolic and VitaalMind, and general vitamins like vitamin D.
We did some research, and while we are not exactly clear on how Vitaae works to improve the memory and cognitive function of its users while helping them reduce phlegm, here are some of what we discovered about its ingredients:
Vitaae was not clinically tested to see if it works; at least, we did not find any evidence of one. However, the ingredients used in the formulation of Vitaae have been clinically tested and approved for some of the benefits claimed by SANESolution.
Randomized placebo-controlled trials of cognitively normal middle-aged and elderly persons showed that Citicoline positively affected memory efficacy.[4] In the same trial, citicoline had a similar positive effect on the memory indices of patients suffering from mild cognitive impairment and other neurological diseases.
Folic acid is another vital ingredient in Vitaae, and a systematic review and meta-analysis of randomized controlled trials on the effect of folic acid supplementation showed that it had a positive impact on memory score when administered in doses lower than 1 mg/day and for longer durations in patients aged 70 years and older. [5]
Vitaae contains about 670 mcg of Quatrefolic, a proprietary form of folic acid developed by SANESolution, which is less than the 1 mg suggested by the research. However, the website suggests that at least two tablets of Vitaae should be taken daily for the best results, which adds up to a little over 1.2 mg of folic acid.
Most importantly, the ingredient VitaalMind, which seems to be where the supplement got its name from, is a proprietary blend of L-Cartinine, L-Acetyl-Carnitine, and L-Tartrate, and Gymnema extract (leaf) claimed by SANESolution to help support your mental clarity and provide deeper concentration.
A review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis showed that l-carnitine supplementation provides a modest reducing effect on body weight, BMI, and fat mass, especially among adults with obesity.[6]
Vitaae relies on the combined effect of its individual ingredients to deliver the results advertised on the product’s website.
Vitaae Ingredients – Are They Safe & Effective?
The team at SANESolution claims the ingredients in Vitaae are carefully selected and blended to provide its users with improved cognitive function and reduce phlegm and age-related symptoms.
Here is a list of the ingredients in Vitaae:
Citicoline Sodium (100 mg) –
Citicoline is a brain chemical found naturally in the body and was originally a prescription drug in Japan aimed at increasing brain function. According to several research studies, Citicoline increases a brain chemical called phosphatidylcholine.[7]
Citicoline is the generic name of cytidine-5’-diphosphocholine (CDP-choline), a compound known to help increase the levels of neurotransmitters in the central nervous system by increasing the production of phosphatidylcholine and other phospholipids. This action is known to improve brain function. However, for this effect to occur, Citicoline needs to be administered in a dosage of 500-2000mg daily.
Vitaae contains only 100 mg of citicoline Sodium, which is insufficient to cause the effect promised by the SANESolution.
Vitamin D (as cholecalciferol) – 125 mcg (5,000 IU) –
Vitamin D is found as Cholecalciferol in Vitaae in a dosage of 125 mcg per tablet. Vitamin D is an essential nutrient required by the body to function properly. Laboratory studies of vitamin D have shown that it can help the body absorb and retain calcium and phosphorus – both elements are crucial in the growth of the human bone.[8]
More importantly, vitamin D can reduce cancer cell growth, infections, and inflammation.
Our article on the benefits of vitamin D3 for men and women shows that vitamin D3 can help people fight off the development of flu and other types of respiratory infections.
Quartrefolic (Proprietary form of folate that is claimed to be more bioavailable) – 670 mcg DFE –
Vitaae contains a proprietary form of folic acid called quartrefolic, which SANESolution claims are more bioavailable than the generic form of folate, which can help with faster absorption.
Studies have shown that folic acid can improve brain function, especially in people aged 70 and above, especially when taken at a dosage less than 1 mg/day. However, the recommended daily dosage of two tablets of Vitaae per day exceeds the recommended dose of folic by about 0.2 mg.
After thoroughly researching the dosage of folic acid used in Vitaae, it is safe to say a user should potentially feel an increase in brain function after taking the supplement for an extended period.
Vitaalmind Proprietary Blend (Packed with Omega-3 fatty acid (EPA/DHA)) – 1560 mg –
VitaalMind is perhaps one of the most critical ingredients in Vitaae as it is a proprietary blend of L-Cartinine, L-Acetyl-Carnitine, and L-Tartrate, and Gymnema extract (leaf) claimed by SANESolution to help support your mental clarity and provide deeper concentration.
According to research, the compounds found in VitaalMind can lead to a reduction in weight, fat mass, and BMI. Essentially, VitaalMind is why many Amazon reviews mention weight loss in one context or another.
The research results on L-carnitine and similar compounds show that the weight loss caused by these compounds does not affect other aspects of the body’s function. It is still unclear how long-term usage of Vitaae will affect the body.
HydroQsorb (Proprietary Coenzyme Q-10 Cyclodextrin Complex) – 50 mg
HydroQsorb is what SANESolution describes as its superior bioavailable form of CoQ10, also known as Coenzyme Q10.
CoQ10 is an enzyme found in almost every cell in the body and is responsible for converting food into energy. An article by Mount Sinai states that CoQ10 is a powerful antioxidant that helps to reduce damaging particles in the body known as free radicals.[9]
Free radicals are known to cause cell death, damage cell membranes, and tamper with DNA.[10]
Research about the use of Coenzyme Q10 supplementation in aging and disease found that: “The ability of CoQ10 to protect against the release of proinflammatory markers provides an attractive anti-inflammatory therapeutic for the treatment of some human diseases and in aging.”[11]
While the effect of CoQ10 is significant, the absorption is extremely slow, and most of it is eliminated from the body as feces. This is why a high dosage is required to have the desired effect in humans.
However, SANESolution claims that HydroQsorb has superior bioavailability, which means it is expected to be absorbed by the body faster and not require a high dosage like the generic version of the compound.
It is difficult to assert this claim as no clinical trials affirm these claims.
Based on our research and review of the evidences available online we do not recommend that you buy Vitaae to help with symptoms like brain fog, memory loss, and other cognition-related problems.
However, we would recommend Vitaae to anyone having problems with throat phlegm and needs a supplement to provide relief.
How to Use Vitaae
According to the website and several reviews on Amazon, here is a guideline on how to use Vitaae and get the most benefit out of it:
- SANESolution recommends that you take two (2) tablets once a day with a meal.
- You can take more than two tablets per day depending on your needs, but it is recommended that you take at least two in a day.
- Add a good diet and daily exercise to your lifestyle alongside taking Vitaae for better results.
- Vitaae comes as a bottle of 30 tablets and it typically lasts for 15 days based on the recommended dosage.
- Several user reviews say the tablet has a fishy taste even though the label says it’s tasteless.
Note: Like every other supplement on the market, the results experienced after taking Vitaae will vary based on lifestyle, sleeping habits, and pre-existing medical conditions.
Vitaae – FAQs
Q: Does Vitaae Work for Throat Phlegm?
A: Many users mention that Vitaae helps them reduce or, in some cases, stop their phlegm problem as long as they continue using it.
Q: How Long Does It Take for Vitaae to Work?
A: Most reviews on Amazon say that they feel the effect of Vitaae on their throat phlegm a few minutes or hours after using it. However, depending on the user, the effects only last a few hours or a day.
Most reviews on Amazon say that they feel the effect of Vitaae on their throat phlegm a few minutes or hours after using it. However, depending on the user, the effects only last a few hours or a day.
Also, most users report that their throat phlegm issues return after they stop using Vitaae. So, you need to continue using the products to enjoy the results.
Regarding memory performance, most users admit that it took about three to four weeks to feel any change in their cognitive abilities.
Q: Does Vitaae Come in a Capsule Or Tablet?
A: Vitaae used to come in a capsule, but it now comes as tablets. There are typically 30 tablets in a Vitaae bottle.
Q: Is Vitaae FDA approved?
A: According to SANE’s customer care, the FDA does not certify dietary supplement products such as SANE Vitaae. However, they state that Vitaae is manufactured in an FDA-registered facility.
Q: How Many Pills are in a Vitaae Bottle?
A: There are 30 tablets in a Vitaae bottle.
Q: Can I Take Vitaae Without a Meal?
A: It is recommended that you take two (2) tablets of Vitaae a day with a meal.
Q: Where Can I Buy Vitaae?
A: You can buy Vitaae on SANESolution’s official website and Amazon.
Q: Does Vitaae Help to Boost Memory?
A: No clinical evidence shows that Vitaae can help boost your memory in any way. However, some of the ingredients used have been clinically proven to help repair the neurological connections in the brain and the central nervous system in general.
Q: Does Vitaae Have Side Effects?
A: The ingredients contained in Vitaae have been clinically tested, and very few side effects are expected at the dosage in which they are used in Vitaae.
Plus, lots of customer reviews mention that they experienced little to no side effects after using Vitaae.
Q: Is There a Return Policy for Vitaae?
A: SANESolution offers a 1-year money-back guarantee on every Vitaae sold. However, many customer reviews on Amazon say the company does not honor it.
Q: How Much Does Vitaae Cost?
A: A single bottle of Vitaae costs $47 on the official website. Purchasing three (3) bottles at once costs $126, and buying six (6) bottles at once costs $198.
Q: What are the Benefits of Taking Citicoline Supplements Like Vitaae?
A: Research shows that Citicoline helps increase the levels of neurotransmitters in the central nervous system by increasing the production of phosphatidylcholine and other phospholipids. Many supplement manufacturers claim that Citicoline supplements like Vitaae can help you think clearer, feel better, boost memory, and improve concentration.
Vitaae Reviews by Customers
Here are a few reviews from customers on Amazon that illustrate their experiences with Vitaae:
These are tablets, not capsules
“I decided to make a purchase on Amazon, believing I was getting the capsules that many people have been raving about. The product description clearly mentioned capsules and touted them as tasteless. However, despite mentioning a change in appearance, the product was still in tablet form, not capsules. Initially, I had purchased these from their official website at a more affordable price. This time, I opted for Amazon, thinking I was getting the capsule version.
Surprisingly, the tablet form seems to be effective for me, even though it wasn’t my original choice. It has had a positive impact on my overall well-being, and I’ve noticed a reduction in abdominal pain that had been bothering me for several months. However, I must admit that the cost of these vitamins is exorbitant for a 15-day supply..” – Patricia.
Words from Toff Old Bird
“Upon initially purchasing this product, I was absolutely delighted. After years of experiencing morning coughing fits, it seemed like my problem was finally solved. However, this happiness was short-lived. When I first started using these supplements, they were in the form of soft capsules, and they worked like a charm.
Unfortunately, the product has since transitioned to hard pills, and I’m not certain if they made other changes along the way, but I find myself returning to my old coughing issue. It’s possible it could be related to the changing seasons or just a personal reaction. I haven’t discontinued using them entirely, as I’m curious if it might be due to the spring weather, and I plan to provide an update later this summer.
Now, three weeks into using the solid pills, I must advise you to save your money. I’ve reverted to my habit of coughing every morning, and I’m no longer inclined to continue with them. If anyone happens to have the soft capsules, I’d appreciate learning more about them and what makes them different.” – Toff old bird.
Change back to Capsules
“I found this product to be quite effective when it was available in capsule form. It provided relief for my phlegm issue and the constant need to clear my throat. However, to my dismay, it was suddenly changed to these large tablets. I would strongly urge the manufacturer to consider reverting to the previous capsule format, as capsules are significantly easier to take and more convenient for users like myself..” – Georgiann Rosado.
The new pills are chalky green
“I was quite satisfied with my initial purchase, which included 45 easy-to-swallow capsules. However, my second order left me rather dissatisfied as it contained only 30 tough-to-swallow green tablets. This discrepancy was particularly disappointing given that the advertisement still displayed an image of 45 tablets, leaving me feeling deceived.
Regarding the product’s effectiveness, I have noticed an improvement in my phlegm condition. However, due to the challenging nature of swallowing the tablets, I can only manage to take one per day with my dinner, which is the closest time to when I experience the issue. As for my mental capacity, I haven’t observed any decline thus far, making it difficult to draw any definitive conclusions in that regard.” – Donna D. Krug.
How Much Does Vitaae Cost?
You can purchase Vitaae directly from SANESolution’s official website or the official store on Amazon.
If you purchase Vitaae from SANESolution’s official website, you get offered three price tiers.
The price tiers are:
- One (1) bottle of Vitaae is $47
- Three (3) bottles of Vitaae cost $126 ($41.98 per bottle)
- Six (6) bottles of Vitaae cost $198 ($32.97 per bottle)
The Website Advertises a Full 1-year money-back guarantee. However, many reviews on Amazon state that the company does not offer any kind of money-back program after purchase.
Note: Vitaae is currently out of stock on Amazon.
Vitaae Review – Conclusion
Many brain-boosting supplements on the market claim to offer remarkable changes to your cognitive function and clarity, but not many deliver on that promise.
In the case of Vitaae, a careful review and analysis of this product reveals a lack of substantial scientific research, independent studies, and user testimonies that suggest that this product helps to improve the memory function of its users in any way.
The substantial lack of external evidence and peer-reviews of this product that validate its manufacturer’s claims makes it hard to understand its real-world performance.
So, while we do not recommend that you get Vitaae if your primary aim is to improve your cognitive performance, lots of reviews praise Vitaae for helping them relieve their throat phlegm as long as they continue using it daily.
Also, one of Vitaae’s effects is mild weight loss, so you should consider that before making a purchase.
More than ever people of all ages are struggling with memory problems. People are unable to disconnect from their work, while students are under immense pressure to perform. Brains are overloaded with information that must be remembered. A quality memory enhancement product might contain clinically proven ingredients that will help to enhance not only memory, but also focus and night concentration. Memory products might help to optimize overall mental health and brain function.
Below you'll find some of the most effective memory products on the market today, in our opinion.
Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned brain health supplements and nootropic based on the available research:

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