The One – Biohacking Cream With Serotonin Review: Does It Work?

The One-Biohacking Cream with Serotonin is an all-in-one skincare product designed to give your skin an instant plumping effect while it gets rid of age-related skin blemishes.

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In This Review

Overview of The One – Biohacking Cream with Serotonin

Are you struggling with skin blemishes such as wrinkles, fine lines, dark spots, and persistent dry skin? If so, don’t allow them to lower your self-esteem and confidence. Discover the transformative power of THE ONE-Biohacking Cream with Serotonin from FACEM Beauty brand and start living your life again.

The cream is formulated using one powerful ingredient – serotonin believed to have the ability to address multiple skin concerns, especially age-related skin ones. THE ONE Cream with Serotonin’s main aim is to ensure that you continue enjoying youthful glowing skin regardless of your age.

What is The One – Biohacking Cream with Serotonin?

THE ONE – Biohacking Cream with Serotonin is a skincare product from the FACEM Beauty brand featuring only one ingredient- serotonin. The cream is designed to help counter age-related symptoms by slowing down the aging process so that you can continue enjoying endless glowing youthful skin.

It has been shown to have a positive effect on a variety of age-related skin concerns like fine lines, wrinkles, skin dryness, dark spots, etc. But does it really work? Keep on reading to learn more about this serotonin cream from FACEM Beauty including how it works, possible side effects, where to buy it, and much more.

How Does The One – Biohacking Cream with Serotonin?

Overall Rating: 4.8
One - Biohacking Cream with SerotoninOne – Biohacking Cream with Serotonin

Ingredients Quality

4.7/5Ingredients Quality
Value for Cost

4.5/5Value for Cost
Return Policy

4.8/5Return Policy


Product Highlights

  • Features science-backed ingredient
  • Backed by a refund policy
  • Contains no filler ingredients or harmful chemicals
  • Has celebrity backing

Key Ingredients

  • Serotonin


  • Hydrates and nourishes the skin leaving it smooth and supple
  • Reduce the appearance of wrinkles and fine lines
  • Fades away dark spots
  • Tightens and firms the skin
  • Ensures overall skin health


  • You can only buy it online on the official website
  • Only one ingredient revealed

Who is the Manufacturer of The One – Biohacking Cream with Serotonin?

Kerri Kasem is the brain behind The One – Biohacking Cream with Serotonin. This unique formula is a result of the many years of hard work and experience she has accumulated.

This makes her among the authorities in the field of anti-aging which has enabled her to earn the trust of beauty enthusiasts and celebrities.

With the support of Angie Chicon, a chemist, she has been able to perfect this Serotonin cream because she believes in offering a product that yields results.

Kerri affirms that the FACEM Beauty brand is not all about products but about the empowerment, unwavering belief, and self-assurance you and other users deserve so that you can feel and look your best every day.

How Does The One – Biohacking Cream with Serotonin Work?

The body produces serotonin naturally using sun rays and as we mentioned in our content titled Awaken XT Review, the ingredient Serotonin is a precursor to melatonin, a neurotransmitter hormone produced naturally by the intestine and brain. Medically, this hormone is referred to as a 5-hydroxytryptamine.

When the light gets into the eyes, it triggers parts of the retina responsible for signaling the brain to create serotonin. So, lack of sunlight, therefore, affects the natural production of serotonin in the body, leading to its deficiency.

The imbalance of this serotonin hormone causes the body to begin experiencing premature aging, unwanted breakouts, and chronic skin conditions like eczema, atopic dermatitis, seborrheic psoriasis, etc[1].

That is where THE ONE cream with serotonin comes in handy. It works to balance the serotonin hormone so that you can achieve clear, radiant, and healthy skin. This cream is known for its role in regulating skin health, digestion, appetite, mood, and sleep.

The ability of the serotonin hormone to contribute to a balanced mood and quality sleep makes it rare for one to experience hormone stress-related surges that can possibly lead to skin cell damage and breakouts.

Various studies have linked abnormal serotonin receptors to skin conditions like psoriasis, eczema, and atopic dermatitis, meaning that a balanced brain equals balanced skin. This explains the existing connection between mental/emotional stress and undesirable skin conditions.

The One – Biohacking Cream with Serotonin Ingredients – Are They Safe?

The One – Biohacking cream is formulated using only one ingredient – serotonin. This ingredient serotonin is discussed below with supporting links to scientific research.


Serotonin is an ingredient naturally produced in the body and has been found to have a positive effect on skin health.
Serotonin has been studied and found to have the ability to increase anti-inflammatory responses. It has also been shown to help in skin barrier repair and improve microcirculation. All these are crucial for enhancing the skin’s glow and for giving anti-aging treatment.

A research study published in the International Journal of Molecular Science investigated the role of serotonin in regulating the skin wound healing process. The results of the study show that serotonin has a potential therapeutic effect, making it a potential ingredient for skin healing especially on burnt skin[2].

Another investigation published in Cells Journal looked into how serotonin is connected to brain-skin health; and the pathogenesis of psoriasis, eczema, and atopic dermatitis. The study established that serotonin may have a positive effect on eczema, atopic dermatitis, and psoriasis types of skin diseases[3].

A similar study was conducted and published in Scientific Reports but this time to investigate if serotonin uptake inhibitors can help improve skin barrier in patients suffering from anxiety. The results of the study show that the skin barrier of patients with anxiety improved after the use of a selective serotonin reuptake inhibitor[4].

Serotonin and Melatonin have been found to offer health benefits to the human body including improving sleep quality and regulating the circadian rhythm (sleep cycle), crucial for maintaining healthy skin and general body wellness.

Research in Inflammation and Allergy Drug Targets looked into the effects of sleep deprivation on skin aging and the counteracting role of serotonin[5].

Verdict: We approve of the key ingredient in this skincare cream because it has been extensively researched and clinically tested and proven to offer the claimed health benefits to the skin with zero side effects.

We Tried The One – Biohacking Cream with Serotonin – Our Take

To determine if THE ONE Cream containing serotonin as the only ingredient can actually work to offer the purported skin health benefits, I decided to try out this cream. After applying the cream for a few weeks, the first thing it did to my skin was hydrating it. I could feel the softness and suppleness of my skin. The thick wrinkles and dark spots on my face began to diminish. Having had a first-hand experience with this product, I can confidently say that it works to fulfill its promise and I wouldn’t hesitate to recommend it to anyone.

Benefits of The One – Biohacking Cream with Serotonin

Hydrates and nourishes the skin: Studies have shown that skincare creams with serotonin like THE ONE can help nourish and hydrate the skin, leaving it smooth and supple.

Reduces wrinkles and fine lines appearance: Application of THE ONE cream has been shown to have an effect on wrinkles and fine lines. It helps in reducing their appearance, hence improving the skin texture and appearance.

Fades away dark spots: THE ONE Serotonin cream has also been tested and proven to reduce the appearance of age-related dark spots.

Tightens and firms the skin: THE ONE has also been shown to help in tightening loose skin because of the firming effect of serotonin.

Enhances the skin’s overall health: THE ONE Biohacking Cream with Serotonin is an all-in-one product with the ability to address a wide range of age-related skincare concerns.

It has, therefore, been noted by celebrities and beauty enthusiasts as among the best skincare products with the ability to improve the skin’s overall health.

The One – Biohacking Cream With Serotonin – FAQs

Q: Does The One – Biohacking Cream with Serotonin Have a Return Policy?

A: All FACEM Beauty products including The One – Biohacking cream are backed by 30 days return policy. If you are not pleased with your order or wish to return it for any other reason, you should do so within 30 days from the date of purchase in exchange for a full purchase price refund minus the shipping fee.

Note that the company currently does not have a product replacement option. So, they are only able to refund you your money for any returned item.

Q: Where Can I Buy The One – Biohacking Cream with Serotonin?

A: You can buy The One – Biohacking Cream with Serotonin by visiting the official website. Currently, it is not available in any online retail shop or local store.

Q: Does The One – Biohacking Cream with Serotonin Have Any Side Effects?

A: The One – Biohacking Cream with Serotonin is a carefully formulated skincare product following many years of research to ensure that the product works to give you your anticipated results without causing any undesirable side effects.

However, serotonin imbalance in the body has been associated with skin-related side effects like itchy skin.
Should you notice such symptoms while using this cream, you should discontinue and see a dermatologist if necessary.

Also, if you have sensitive skin, consult with a dermatologist for advice regarding the use of this cream before fully committing to it.

Q: How Should You Take The One – Biohacking Cream with Serotonin?

A: There is currently no usage direction given on the official website to guide users on how many times one should apply The One Cream.

Meanwhile, doing research to understand how THE ONE alternative creams are used my give you an idea of how you should apply it.

Alternatively, before adding the cream to your skincare daily routine, we recommend consulting with a dermatologist regarding the usage dose/directions.

Q: What Sets The One – Biohacking Cream with Serotonin From the Competition?

A: Unlike other skincare products that have filler ingredients and harmful chemicals that expose the skin to a number of undesirable side effects, THE ONE – Biohacking Cream has only one ingredient – serotonin which has proven to work to give real results as a stand-alone ingredient.

Again, unlike other products designed to manage only one skincare concern, The One – Biohacking Cream is an all-in-one product that targets a wide range of skin concerns.

Q: How Much Does The One – Biohacking Cream with Serotonin Cost?

A: The price of The One – Biohacking Cream with Serotonin as given on the official website is $159.

What Do the One-Binhacking Cream with Serotonin Reviews Say?

We obtain most of our reviews from independent websites like Amazon because we believe reviews found on such websites are unbiased and reflect the true opinion of the buyer.

Unfortunately, this product is currently being sold only on the official website. You won’t find it in any online retail shop or local store.

However, the fact that this product has caught the attention of celebrities and beauty enthusiasts we are confident that the reviews on the official website are also genuine and reflect the true opinion of the first-hand users of this product.

The One-Biohacking Cream with Serotonin has a good number of reviews from people who have tried the product and experienced real results.

One of our top reviewers Karen B., says,

I am more than pleased, the product plus the services is fantastic.

Kimberley R. also another top reviewer says,

My skin’s health has generally improved since I started using this cream. I am planning to place another order soon before it runs out before the one, I am using runs out.

Dorothy K. another top reviewer says,

This cream is the best skincare product I have ever tried since I started experiencing wrinkles and fine lines on my face.

Another top reviewer Alison N. says,

This product has transformed my skin appearance. The fact that it only contains one ingredient makes me fall in love with it even more. I highly recommend this product without any reservations.

The One – Biohacking Cream With Serotonin Review – Conclusion

THE ONE – Biohacking Cream with Serotonin is an anti-aging authority that has earned the trust of renowned celebrities as well as beauty enthusiasts, there is no doubt that is one of the best anti-aging creams out there you can trust.

For this company, ingredient quantity does not define product efficiency but rather ingredient quality and strength.
This formula therefore formulated using only one powerful ingredient, serotonin which has plenty of scientific backing as a substance with the ability to positively affect a number of physiological processes including skin aging.

If you desire to transform your skin appearance and achieve youthful glowing skin, consider giving THE ONE Serotonin Cream a shot.

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for The One – Biohacking Cream with Serotonin

The One – Biohacking Cream With Serotonin Review: Does It Work?

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The One – Biohacking Cream with Serotonin
1.7 oz (48g)

5 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Premature aging syndrome
[2] The Role of Serotonin During Skin Healing in Post-Thermal Injury
[3] The Brain-Skin Connection and the Pathogenesis of Psoriasis: A Review with a Focus on the Serotonergic System
[4] Psychological Stress Deteriorates Skin Barrier Function by Activating 11-B-Hydroxysteroid Dehydrogenase 1 and the HPA Axis
[5] Brain-Skin Connection: Stress, Inflammation and Skin Aging

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

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