Dermafreeze365 Reviews – Does It Work As Anti-Wrinkle?

Dermafreeze365 is an Anti-Wrinkle product made with natural ingredients that claim to reverse aging by eliminating wrinkles, sagging skin, and fine lines.

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In This Review

What is Dermafreeze365?

Dermafreeze365 is a product that helps decrease the signs of aging by temporarily ‘freezing’ the facial muscles. There are many of these so-called ‘instant’ face lift products available on the market although some, like Dermafreeze365, also claim to have long term results too.

There is no official website for the Dermafreeze product, which is manufactured by Woodrige Labs, but it is sold online by Jocott Brands, who do offer some information about it.

How Does It Rate?

Overall Rating: 3.7

Value for Cost

3.9/5Value for Cost
Return Policy

3.1/5Return Policy


Brand Highlights

  • Dermafreeze 365 is manufactured by Woodrige Labs, but it is sold online by Jocott Brands.
  • The manufacturer claims that you can reduce the appearance of signs of aging.
  • According to the manufacturer, the formula is clinically proven.


Beverly Hills MD Deep Wrinkle Filler

*All individuals are unique. Your results can and will vary.

Key Ingredients

  • Sesame Seed Oil
  • Licorice Root Extract
  • Aminobutyric Acid
  • Butylene Glycol


  • May reduce the appearance of fine lines and wrinkles
  • Might reduce laugh lines
  • Could improve elasticity of the skin
  • May moisturize the skin


  • Not all ingredients are listed
  • There is no money back guarantee

How Does Dermafreeze 365 Work?

All that is known is that it contains a patent-pending blend called GABA-Biox.

In clinical tests, this substance did reduce lines and wrinkles by 50-90% in ten minutes and works mainly by relaxing the facial muscles, smoothing out wrinkles, and helping to prevent future lines from forming.

Ingredients in DermaFreeze365

Sesame Seed Oil

Sesame oil, [1] which has moisturizing fatty acids and is a good source of vitamins E, D, and B, is used in skin care because of its ability to repair and regenerate skin. It has the power to penetrate deeply into pores, aiding in the process of working from the inside out and enhancing blood circulation.

Licorice Root Extract

This root extract, [2] used in skin care products for its anti-inflammatory and antioxidant properties, can also brighten and moisturize skin. Some skin types may find its aroma irritating.

Aminobutyric Acid

Gamma-Aminobutyric Acid (GABA), [3] a naturally occurring amino acid that the body uses as a muscle relaxant, is the main active component in the formula. This is what gives the cream its “freezing” effect. The other ingredients in the formula are used to increase circulation and enhance penetration because GABA is difficult to absorb through the skin. This sends a signal to the skin receptors to relax muscles.

Butylene Glycol

Petroleum-derived chemical substance that functions as a solvent, thinner, and conditioning ingredient in skin care products. Petroleum-based compounds can smother skin, block pores, and worsen acne symptoms.

There are no instructions regarding the application, but it can be applied under regular moisturizer and can also be worn under makeup.



*All individuals are unique. Your results can and will vary.

FAQ For Dermafreeze365

Q: What Are The Side Effects Of Dermafreeze365?

A: As of now there have been no side effects reported by users who have used the Dermafreeze365. But some negative reviews are mention on another e-commerce site.

Q: How Much Does Dermafreeze365 Cost?

A: Dermafreeze365 is an expensive product, and it can be purchased on its official website. It is available at the cost $39.99.

Q: Does Dermafreeze365 Provide A Free Trial Or Refund Policy?

A: The company does not offer any free trials of the cream. And very limited money back guarantee, but larger orders are subject to discounts.

Q: Is Dermafreeze365 Cruelty Free?

A: Yes, brand claim that it is a cruel-free product.


Beverly Hills MD Deep Wrinkle Filler

*All individuals are unique. Your results can and will vary.

Dermafreeze365 Review – Final Verdict

This type of product can be good to use before a special occasion or whenever the need for an instant effect is needed.

Although it has proved to work in the short term, it would be useful to see how well it performs over time, and many consumers may want to also use a more intense anti aging cream for long term results.

However, there are many better options in the market which might offer more benefits than these products. Explore such options before making the final decision of buying this product.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you'll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.

Our Top Wrinkle Cream Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned anti-aging products and anti-wrinkle creams based on the available research:

Beverly Hills MD - Best #1 Rated Skincare Brand
Brand SealBeverly Hills MD
Innovative Science-Backed Skincare Products*Gold Star Evidence
Range of Products for Specific Skin Concerns*Gold Star Evidence
Cruelty-Free, Premium Quality Ingredients*Gold Star Evidence
Visibly Lifts Skin From The Inside, Out*Gold Star Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Read Review
Deep Wrinkle Filler | Anti-aging Skin Care Formula
Erase The Appearance Of Fine Lines*Gold Star Evidence
Fill in Deep Wrinkles*Gold Star Evidence
Give Skin a Smoother, More Flawless Appearance*Gold Star Evidence
Nourishes Skin For Lasting Results*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
DRMTLGY | Dermatologist Recommended Beauty Line
Offers Fragrance-Free & Hypoallergenic Products*Gold Star Evidence
Formulates Medical-Grade Skin Solutions*Gold Star Evidence
Provides Personalized Skincare Regimens*Gold Star Evidence
Prioritizes Customer Satisfaction*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
XYZ Smart Collagen | The Best Collagen Cream
Wrinkles Reduction*Gold Star Evidence
Improves Skin Firmness*Gold Star Evidence
Improves Skin Texture*Strong Evidence
Smart Collagen Management*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Dermafreeze365

Dermafreeze365 Reviews – Does It Work As Anti-Wrinkle?

Customer Reviews & Ratings

3.0 out of 5

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  1. Dorothy

    My experience with Dermafreeze365
    I used this about 10 years ago and it was great. It did shrink wrinkles within minutes. I was not expecting long-term results and don’t know if that happens. But when you really need it (my daughter’s wedding) it works. I just tried it again but after 10 years it did not work. Still, yes, I’d buy it again for immediate results and shall order another right now!
  2. Christen M.

    Only Temporary results
    The results are only temporary. These patches somehow lift the wrinkle out of the skin but the results only last for a day or so and then it’s back to normal. I did 2x per week for 3 weeks and my under eye wrinkles look exactly the same after 24 hours without the patches, every time.

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2.00 Fl Oz
Sesame Seed Oil, Licorice Root Extract, Aminobutyric Acid, and Butylene Glycol.

3 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.
[1] Hsu E, Parthasarathy S. Anti-inflammatory and Antioxidant Effects of Sesame Oil on Atherosclerosis: A Descriptive Literature Review. Cureus. 2017 Jul 6;9(7):e1438. doi: 10.7759/cureus.1438. PMID: 28924525; PMCID: PMC5587404.
[2] Ciganovi? P, Jakimiuk K, Tomczyk M, Zovko Kon?i? M. Glycerolic Licorice Extracts as Active Cosmeceutical Ingredients: Extraction Optimization, Chemical Characterization, and Biological Activity. Antioxidants (Basel). 2019 Oct 1;8(10):445. doi: 10.3390/antiox8100445. PMID: 31581512; PMCID: PMC6826613.
[3] Denda M, Inoue K, Inomata S, Denda S. gamma-Aminobutyric acid (A) receptor agonists accelerate cutaneous barrier recovery and prevent epidermal hyperplasia induced by barrier disruption. J Invest Dermatol. 2002 Nov;119(5):1041-7. doi: 10.1046/j.1523-1747.2002.19504.x. PMID: 12445190.

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

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