Zostrix Reviews – Can This Cream Help Strengthen Joints?

Zostrix is a potent cream-based supplement that has the potency of capsaicin, the natural active ingredient in chili peppers. It's powerful, effective, and odorless.

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In This Review

What Is Zostrix?

Zostrix is a topical formulation which works as an analgesic using the primary ingredient purified capsaicin. It temporarily relieves minor aches and pains of the muscles and joints. The formula uses a natural active ingredient that is clinically proven to relieve pain.

It is even safe to use with oral pain relievers like non-steroidal anti-inflammatory drugs because the topical formulation is all-natural. The formula is even effective for neuralgia pain.

How Does It Rate?

Overall Rating: 3.7

Value for Cost

3.7/5Value for Cost
Return Policy

3.6/5Return Policy


Brand Highlights

  • Zostrix acts naturally as a pain relief cream for the toughest pain points
  • Our Maximum Strength formula helps to naturally block your body’s pain messenger
  • Zostrix is odor free and non-greasy
  • Zostrix Natural Pain Relief Cream provides a warm, penetrative relief derived from chili peppers
  • Product contains Capsaicin 0.1% topical analgesic



*All individuals are unique. Your results can and will vary.

Key Ingredients

  • Total Capsaicin – 0.1 %


  • Zostrix is an all-natural formulation.
  • Studies have shown that it helps reduce pain.
  • It is available in most pharmacies and supermarkets.


  • There is no clinical study showing that the product is really effective.
  • It is not offered with a money-back guarantee.
  • There are some users who find the hot sensation from the application unbearable.
  • It is not always effective especially when it comes to severe pain.
  • Some people are highly sensitive to the main ingredient.

How Does Zostrix Work?

This joint supplement contains an active ingredient that reduces one of the major pain transmitters in the body, thus reducing pain gradually until it disappears. It also has a warming effect on the skin, which helps reduce the primary pain by distracting the brain.

When the formula is used several times on a particular area, it is desensitized so the user will no longer feel the pain in said area. There might be some other topical joint pain relief formulas available to treat the joint pain.

Zostrix Ingredients – Are they Safe & Effective?

The only active ingredient in Zostrix is purified capsaicin which is a common active ingredient in topical analgesic creams. The ingredient is derived from chilli peppers and the purified form works at a pharmacological level.

It has been shown to block the transmission of pain by reducing the availability of Substance P in the area where it is applied. Substance P is one of the primary ‘pain messengers’ in the body so decreasing it directly reduces pain in the area where it is applied.

Pain decreases gradually with the regular application until the cumulative depletion of Substance P results to substantial pain relief which is usually in 4 to 6 weeks.

Total Capsaicin – 0.1 %

-This medication is used to treat minor aches and pains of the muscles/joints (such as arthritis, backache, sprains). Capsaicin works by decreasing a certain natural substance in your body (substance P) that helps pass pain signals to the brain.[1]



*All individuals are unique. Your results can and will vary.

Zostrix – FAQ’s

Q: How Should You Take Zostrix?

A: Apply Zostrix on the affected area/s 3 to 4 times a day. Regular use is important to reduce pain significantly. Massage the cream into the skin on the front, back and sides of the affected area until it is absorbed by the skin. Wash hands thoroughly after application unless you are treating your hands.

Q: What precautions should you take using this product?

A: The formula is for external use only. Keep out of reach of children. Do not apply on broken skin or when the skin in the affected area is irritated. In case of severe skin irritation from Zostrix, wash with water and discontinue use.

Avoid contact with your eyes and do not get the formula in mucous membranes. For children less than 18 years of age, check with a health care professional prior to use.

Q: How Much is Zostrix?

A: One tube container is priced $19.99 online.

Zostrix Review – Final Verdict

All in all, Zostrix is just a mediocre capsaicin-based topical analgesic. There are many similar formulations on the market. The main problem with these joint meds is that some people find them unbearable because of the burning sensation it causes immediately after application.

However, many people also like the sensation since it reduces the pain they are trying to treat. It is not for everyone and the product is mostly effective for minor to moderate pain of the muscles and joints. For more severe types of pain, there are better products on the market.

Bones are connected by joints, which allow us to move with ease. Joint damage can cause pain preventing you from doing the things you once loved. Topical joint relief products tend to work more quickly, helping to relieve pain directly in the affected area compared to products taken orally. A topical joint pain relief product should be evaluated on its: potential to block the transportation of pain signals, potential to act as a counterirritant to reduce soreness and Quality of Ingredients* backed by clinical research.

Below you'll find some of the most effective topical joint pain products on the market today, in our opinion.

Our Top Joint Pain Relief Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned joint pain relief gels, gummies, and creams based on the available research:

Balmorex Pro | Relief and Recovery Cream
Supports Joints, Back, and Muscles*Gold Star Evidence
Reduces Inflammation and Swelling*Gold Star Evidence
Boosts Recovery & Joint Flexibility*Gold Star Evidence
Provides Long-Lasting Pain Relief*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Back to Life | Pain Relief Program
Builds Strong Muscles and Bones*Gold Star Evidence
Increases Flexibility of Joints*Strong Evidence
Reduces Cramps*Strong Evidence
Eases Discomfort in Stiff Areas*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Barker Wellness | Cannabinoid-Infused Products
Nurtures Body & Mind*Gold Star Evidence
Targets Sleep & Focus*Strong Evidence
Wide Range of Products*Gold Star Evidence
Natural and Organic*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Zostrix

Zostrix Reviews – Can This Cream Help Strengthen Joints?

Customer Reviews & Ratings

2.5 out of 5

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  1. J. Webster

    This is not relief pain but put on fire
    My husband and I both applied this to our knees and this medication was so “hot” on our skin we felt like we were on fire. We also tried to wash it off and the burning continued. I then mixed baking soda, dawn, and water and applied it to the area, and showered without relief. As we sit here almost 24 hrs. later the knees are still hot. Cannot confirm this helped with the arthritis pain since the pain from the intense “fire” far surpassed the arthritis pain we have. Would not recommend this product. The tube went straight to the trash.
  2. DanLinh

    4.0 out of 5 stars Good for a natural product
    I’m suffering from knee pain and swelling after the meniscus cleanup surgery. This salve definitely helps deaden the pain temporarily—-enough so I can fall asleep.

    The drawback is the care you have to use to not get it anywhere else including your hands.

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1 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Capsaicin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169333/

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

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