Nuzena Saffron Super Spice + Review: Is It Really Effective?

Nuzena Saffron Super Spice + is a natural nootropic that supports overall mental well-being by enhancing mood, reducing anxiety, and improving memory.

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In This Review

Overview of Nuzena Saffron Super Spice +

Saffron is a spice that comes from a flower known as crocus sativus. It is a bright red spice that is used in many cuisines around the world but is not very common in Western foods.

Saffron as a supplement has many health benefits, mostly having to do with brain function. But in America, we don’t get too much of it in our diet so many Americans are lacking the mental health benefits this spice provides – benefits such as anti-depressant effects.

The National Institutes of Health reviewed a study on the antidepressant effects of saffron and concluded that it was at least as effective as popular prescription antidepressants. They lay their findings in the following quote:

The studies reported that saffron was more effective than placebo and at least equivalent to the therapeutic doses of imipramine and fluoxetine.

As a natural botanical extract, saffron supplementation is much safer and causes no side effects compared to prescriptions like fluoxetine and imipramine.

But if you’re not getting enough saffron in your diet, you could be at higher risk of depression and anxiety. As saffron is somewhat uncommon in Western foods, it could explain why more than 21 million American adults suffer from depression[1] every year.

But saffron is not unobtainable and there are even supplements that can offer you the awesome health benefits of saffron in a convenient capsule. One such supplement is called Saffron Super Spice + and in the following review, we will be taking a look at the formula, the company that makes it, and what you can expect from it.

What is Saffron Super Spice +?

Saffron Super Spice + is a natural nootropic supplement that can help elevate your mood, fend off depressive thoughts, and lower your anxiety. The formula consists of a potent dose of saffron so even if you don’t use the spice otherwise, you can still get all the benefits it provides by taking this supplement.

Saffron Super Spice + was developed by an in-house team of food scientists, dietitians, and healthcare professionals. It was formulated to provide specific nootropic support for memory as well.

How Does Saffron Super Spice + Rate?

Overall Rating: 4.8
Saffron Super Spice +Nuzena Saffron Super Spice +


Value for Cost

4.7/5Value for Cost



Brand Highlights

  • The company takes pride in providing transparent pricing and formula information
  • The 3rd party lab-test all of their supplement products
  • The brand sustainably sources all of the ingredients they use
  • Their products are made in an FDA-registered facility
  • Saffron Super Spice + and all supplements from Nuzena are made in the United States
  • All Nuzena supplements are made from natural, clinically proven ingredients

Key Ingredients

  • Pure Saffron Extract


  • It supports memory recall
  • It can help elevate your mood
  • Taking Saffron Super Spice + can lower your risk of depression
  • This supplement can help your brain manage stress more effectively
  • When taken as directed, Saffron Super Spice + can also reduce your levels of anxiety
  • There is no gluten in the formula


  • Your order of Saffron Super Spice + may not be eligible for free shipping
  • Individual results may vary

You can BUY it directly from the Official Website

Who is the Manufacturer of Saffron Super Spice +?

Saffron Super Spice + is manufactured by a company called Nuzena. Nuzena was founded by Ryan Donald who set out to provide quality health supplements that were sustainably sourced and featured natural remedies. The company emphasizes integrative health solutions and even offers personalized health reporting at no cost to its customers.

How Does Saffron Super Spice + Work?

The consumer should be aware that there is only one active ingredient in the Saffron Super Spice + formula and that ingredient is saffron, of course. So we have to take a look at how saffron works and what effects it has on the body and brain.

According to a National Institutes of Health[2] study review, we learned that there are two active compounds in saffron: crocin and safranal. These two compounds are potent antioxidants and have antidepressant effects as we see in the following excerpt taken from the same study review:

The result showed that saffron at this dose was found to be effective comparable to imipramine in the treatment of mild-to-moderate depression.

By providing antioxidant support to the brain, saffron effectively increases levels of serotonin which are neurotransmitters responsible for mood elevation. As a result, it is a naturally effective solution for alleviating conditions of depression.

Saffron also displays anti-inflammatory effects which could help to reduce the progression of neurodegenerative diseases. In one Frontiers study, it was found that saffron has neuroprotective effects against inflammation which could negate cognitive decline and slow the onset of certain adverse cognitive conditions[3].

Saffron Super Spice + Ingredients – Are They Safe & Effective?

Take a look at the following breakdown of the sole Saffron Super Spice + ingredient:

Nuzena Saffron Super Spice + supplement fact

Nuzena Saffron Super Spice + supplement fact

Pure Saffron Extract

Saffron is a perennial herb that when extracted, is used as a spice. It has displayed many cognitive benefits over the years. For instance, it has been lined with improved memory in clinical trials as we see in the following quote taken from an NIH[4] trial:

A recent study has reported that saffron and its active constituent crocin can prevent oxidative stress damage to hippocampus, memory and learning impairments.

The main active compounds in saffron can therefore protect against the effects that free radicals have on the learning and memory centers of our brain, improving memory and helping to prevent memory-related cognitive decline.

Saffron also has a beneficial impact on sleep quality. In a Journal of Clinical Sleep Medicine[5] study, it was found that:

Saffron supplementation for 8 weeks was associated with improvements in insomnia, sleep quality, and restorative sleep

Sleep quality plays a pivotal role in cognitive performance and ability so improving sleep duration and quality saffron can benefit brain health in yet another way.

You can BUY it directly from the Official Website

Benefits of Saffron Super Spice +

Here are some of the most important Saffron Super Spice + benefits:

Brain Protection: Saffron Super Spice + can protect your brain cells from oxidative stress which preserves healthy cognition.

Improved Sleep Quality: By reducing feelings of stress and anxiety, Saffron Super Spice + can help you get more restful sleep.

Anti-Depressant Effects: Saffron is an effective extract to help stave off depressive thoughts and increase dopamine production.

Antioxidant Defense: Saffron is also rich in potent antioxidants which limit the effects of free radicals in the brain.

Nuzena Saffron Super Spice + Review – FAQs

Q: Is it safe to take Saffron Super Spice +?

A: Yes. Nuzena includes heavy metal and allergen contaminant testing in their production of this supplement.

Q: How to take Saffron Super Spice +?

A: You should take 2 capsules of Saffron Super Spice + daily. For best results one capsule in the middle of the day and one in the evening or as directed by a doctor.

Q: What is the return policy for Saffron Super Spice +?

A: Customers have 30 days from the date of their purchase to return Saffron Super Spice + for a refund.

Q: What sets it apart from the competition?

A: Saffron Super Spice + contains a pure saffron extract so you get all the health benefits this spice has to offer.

Q: Where can I buy Saffron Super Spice +?

A: You can get Saffron Super Spice + on the Nuzena website. On the Nuzena site a single bottle costs is $35. You can lower the price to $29.75 by enrolling in the auto-refill program.

What Do the Saffron Super Spice + Reviews Say?

People seem to love the effects of Saffron Super Spice +. In Saffron Super Spice + reviews, customers have said:

I never Knew about all of the benefits that saffron has to offer. In love with this product! –Paula G

My wife has been taking for 6 weeks now and we’ve both seen a major major difference in not just her mood but also her energy. –Katarina

Been using the super spice formula for 3 months now and its been going great, feel way less anxious and have stopped taking my meds as much. –Kate

Nuzena Saffron Super Spice + Review – Conclusion

Saffron Super Spice + is a natural supplement that has major brain benefits for the user. It can help protect your memory and make it sharper. It can help you get more restful sleep as well.

This supplement can even lower your risk of developing depression and lower your levels of anxiety. Plus, the reviews from confirmed customers have been very positive so far.

We recommend Saffron Super Spice + to anyone who wants better brain function because it is truly a quality nootropic.

Where To Find It?

Pick it up on the Nuzena website for the best deals!

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Saffron Super Spice +

Nuzena Saffron Super Spice + Review: Is It Really Effective?

Customer Reviews & Ratings

5.0 out of 5

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  1. Rachel Turner

    Impressed with saffron super spice + supplement!
    I’ve purchased the Nuzena Saffron Super Spice +, which comes in a pack of 60 capsules, each containing 88.5mg of saffron extract per serving. These vegan and non-GMO capsules are made in the USA and are specifically designed to support eye health, memory, and mood. I’m truly impressed! The capsules are both flavorless and easy to swallow, seamlessly fitting into my daily routine. The fact that they are vegan, non-GMO, and crafted in the USA adds to their appeal. I highly recommend trying out Nuzena Saffron Super Spice + for its numerous benefits.

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    5 Sources

    We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

    [1] Depression:
    [2] Saffron (Crocus sativus L.): As an Antidepressant:
    [3] Neuroprotective Potency of Saffron Against Neuropsychiatric Diseases, Neurodegenerative Diseases, and Other Brain Disorders: From Bench to Bedside:
    [4] Crocus Sativus L. (Saffron) in Alzheimer’s Disease Treatment: Bioactive Effects on Cognitive Impairment:
    [5] Effects of saffron on sleep quality in healthy adults with self-reported poor sleep: a randomized, double-blind, placebo-controlled trial:

    **This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

    *Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

    Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

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