In This Review
Overview
As you grow older and the probability of metabolic issues increases, managing your blood sugar levels and heart function might become difficult.
When your blood sugar fluctuates, you might experience low energy, weight changes, and other issues such as high blood pressure.
While you must have heard that exercise and diet are important for these issues, they’re sometimes simply not enough. That’s why many people turn to supplements for the needed extra support.
Berberine supplements seem to be the go-to for heart health and blood sugar levels. But with so many options available, how do you know which one is worth trying?
Today, we’ll explore one of the options available: Nature’s Truth Berberine.
Can it actually deliver results? This Nature’s Truth Berberine review will help you decide if this supplement will work for you.
Let’s get right into it.
What is Nature’s Truth Berberine?
Nature’s Truth Berberine 500mg is a dietary supplement that claims to support blood sugar metabolism, cholesterol levels, and heart function.
Nature’s Truth claims that their Berberine formulation contains 500 mg of Berberine HCl obtained from Berberine extract. It also claims that the supplement is vegan, non-GMO, and gluten-free.
The company also claims that its Berberine is soy-free, dairy-free, and free from artificial colors, flavors, sweeteners, and preservatives.
But could all these be true?
How Does Nature’s Truth Berberine Rate?

Brand Highlights
- Products are manufactured in the USA.
- Utilizes science-backed ingredients.
- Claims to be certified by GMP
- Claims to operate an FDA-registered cacility
- 3rd-party tested.
Key Ingredients
- Berberine HCl (500 mg per capsule)
Pros
- Vegan friendly
- Uses non-GMO ingredients.
- 45-day money-back guarantee.
Cons
- Potential side effects like digestive discomfort, headaches, or fatigue.
- Some users might find the capsule difficult to swallow or notice a strong chemical aftertaste.
- Mixed customer reviews on effectiveness
- Subscription is required for the best pricing.
- Most users might not experience immediate effects.
- Taking 2 capsules about 3 times daily might not be convenient for most people.
About the Brand
Nature’s Truth is a wellness brand specializing in producing and distributing vitamins, herbal supplements, and essential oils. It is based in the USA and claims it operates in a GMP-certified and FDA-registered facility.
Nature’s Truth claims to focus on science-backed formulas and ensures that its products are non-GMO, gluten-free, and free from artificial additives. The brand says it emphasizes purity and transparency and says that all its supplements are lab-tested for quality and potency.
Nature’s Truth gives a 45-day money-back guarantee, which may encourage users to try their product with less financial risk.
How Does Nature’s Truth Advanced Berberine 500mg Work?
Nature’s Truth Berberine 500mg contains Berberine HCl, a plant-based alkaloid known for its potential benefits in blood sugar regulation, metabolism, and heart health.
Research in the American Journal of Physiology-Endocrinology and Metabolism indicates that berberine enhances glucose metabolism by promoting glycolysis. It is said to achieve this by activating an enzyme called AMP-activated protein kinase (AMPK) [a key enzyme that regulates how the body processes glucose and fat].
Research published in Theranostics shows that Berberine is a traditional Chinese medicinal herb used to treat inflammatory conditions and diabetes mellitus.
Berberine has shown potential in managing cardiovascular diseases such as atherosclerosis and heart failure by offering protective benefits to the heart and blood vessels.
Nature’s Truth claims that its vegan capsules provide a consistent, high-quality dose of Berberine. However, the effectiveness varies based on individual metabolism, dosage, and consistency of use.
Nature’s Truth Berberine 500mg Ingredients: Are They Safe & Effective?
Here’s the key ingredient in Nature’s Truth Berberine 500mg:
Berberine HCl (500 mg per capsule)
Berberine is a natural compound extracted from plants like Barberry and Rhizoma Coptidis. It has been widely studied for its potential use in regulating blood sugar, supporting heart health, and improving metabolism.
Clinical studies have shown that berberine may help regulate glucose and lipid metabolism disorders and enhance insulin sensitivity.
In our EzyAbsorb Berberine Review (another supplement that contains Berberine), Berberine is said to be effective in controlling blood sugar.
Research on the efficacy of berberine compared its effects to certain prescription medications used for blood sugar control and concluded that “berberine may serve as a new drug candidate in the treatment of type 2 diabetes.”
How to Use Nature’s Truth Berberine?
Here is how to take Nature’s Truth Berberine 500 mg:
- Take two capsules two to three times daily, preferably with meals.
Do not exceed the recommended dose unless advised by a healthcare professional. If you have any medical conditions, are pregnant, nursing, or taking medications, consult your health practitioner before use.
Benefits of Nature’s Truth Berberine
Nature’s Truth claims that Berberine 500mg offers several health benefits. Here are some of the claimed benefits:
- Supports Blood Sugar Balance: The brand states that Berberine may help regulate blood sugar levels by improving insulin sensitivity and glucose metabolism.
- Promotes Heart Health: According to Nature’s Truth, Berberine may support cardiovascular function by helping manage cholesterol and triglyceride levels. This could contribute to better heart health and circulation.
- Aids Metabolism: The company claims that Berberine activates AMPK (AMP-activated protein kinase), a key enzyme that helps improve fat metabolism and energy production. This may support weight management and general metabolic health.
It should be noted that these are claimed benefits by the brand. The Food and Drug Administration (FDA) has not evaluated these statements, and individual results may vary.
Side Effects of Nature’s Truth Berberine
Nature’s Truth Berberine is generally well-tolerated when used as directed. However, the manufacturer notes that some individuals may experience mild side effects, including:
- Digestive discomfort such as bloating or mild stomach upset.
- Fatigue or drowsiness due to the use of berberine.
- Headaches
It is advisable to consult a healthcare provider before starting this supplement, especially if you have underlying health conditions, take medications, or are pregnant or nursing.
Safety
Nature’s Truth claims Nature’s Truth Advanced Berberine HCl 500mg is manufactured in the USA using high-quality, globally sourced ingredients. The product is said to be gluten-free, dairy-free, sugar-free, aspartame-free, and vegan-friendly, to ensure it meets various dietary preferences.
However, it’s important to note that you should be cautious if you have any allergies or sensitivities. Some individuals may experience mild digestive discomfort or other side effects due to its active ingredient.
Also, Berberine inhibits cyclosporine breakdown, which may increase its side effects. Those using blood sugar, blood pressure, or anticoagulant medications should consult a healthcare professional to prevent possible interactions.
As with any supplement, it’s best to follow the recommended usage and consult a healthcare provider before starting.
Nature’s Truth Advance Berberine HCl 500mg Price
Nature’s Truth Berberine 500mg is available on the official website. A single bottle contains 60 capsules. Here’s the pricing detail:
For a one-time purchase:
- 1 Bottle costs $16.99
When you subscribe for three bottles every 3 months, you save 10% where
- 1 Bottle costs $15.29
The prices are very similar to those on Amazon; you can also purchase them from Walmart as an additional option. However, products purchased on Amazon do not come with a money-back guarantee.
Nature’s Truth Berberine Review: FAQs
Q: Does Nature’s Truth Berberine help with weight loss?
A: Some research suggests Berberine may aid metabolism and fat regulation. However, results vary, and it works best alongside a healthy diet and exercise.
Q: Is Berberine safe for people with diabetes?
A: Berberine may help regulate blood sugar but can interact with diabetes medications. Always consult a healthcare provider before adding it to your routine.
Q: Can Berberine lower blood pressure?
A: Studies suggest Berberine may have a mild blood pressure-lowering effect. If you take blood pressure medication, talk to your healthcare provider before use.
Q: Can I take Berberine with probiotics or other supplements?
A: Yes, Berberine is often combined with probiotics for gut health. However, check with a health practitioner before mixing it with other supplements.
Q: Does Berberine interact with antibiotics?
A: Berberine has antimicrobial properties and may interact with certain antibiotics. If you’re taking antibiotics, speak to your healthcare provider before using Berberine.
Q: Can I take Berberine 500mg long term?
A: Berberine can be taken long-term, but it’s best to cycle its use (e.g., 8 weeks on, 2 weeks off). Consult a healthcare provider for personalized guidance.
What Do the Nature’s Truth Berberine Customer Reviews Say?
Here’s what some valid users say:
Lea gave the product a 5-star rating, saying These seem like good quality. Working well for me personally. I take these with food and no side effects other than I feel a little tired. For the benefits, that’s ok.
Cynthia Z. gave it a 4-star in her opinion, They are strong chemical taste capsules. She said “They really control my appetite unlike the more expensive brand. Controls my blood sugars have lost about 8 lbs in one month with diet. The capsules have a really strong taste like chemicals.
Tina Smith gave it a 3-stars in her opinion it is not effective. She said This was the second brand of Berberine I tried and will not be repurchasing this one. Did not see any results with bloating or suppressing appetite.
D car gave it a 1-star saying, I thought I had a stomach virus for two weeks, but it turns out I was getting sick from the berberine.
The customer opinions are mixed. Some users report benefits like weight management, blood sugar level support, and optimal wellness, while others say it did nothing for them. It has a strong chemical taste, and some claim to suffer from side effects from the berberine used in the product.
Nature’s Truth Advanced Berberine Review: Conclusion
Nature’s Truth Advanced Berberine 500mg claims to support blood sugar balance, promote heart health, and aid weight management.
Some users report benefits like improved metabolism, appetite control, and stable blood sugar levels. However, others say they noticed little to no change, while some experienced side effects like digestive discomfort and fatigue.
The product’s pricing is reasonable, especially with subscription savings. Although it is vegan, non-GMO, and gluten-free, the strong taste and mixed customer reviews may be a drawback for some.
Nature’s Truth Berberine might be worth trying if you’re looking for a natural way to support blood sugar and metabolism. However, results vary from person to person. If you prefer a more consistent supplement with better reviews, you might want to explore other Berberine supplements with higher user satisfaction.
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