SkinFresh MD Review – Does SkinFresh MD Skincare Actually Work?

A popular anti-aging skin care product, SkinFresh MD is designed to moisturize and restore skin's radiance while counteracting the signs of aging.

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In This Review

What is SkinFresh MD?

SkinFresh MD is a cutting-edge, premier wrinkle skin care product. This rich cream not only tackles the signs of aging, restoring skin radiance, but it also acts as a moisturizing agent to replenish skin hydration levels. This allows you to restore a radiant, youthful glow as fine lines, age spots and wrinkles are eliminated.

How Does It Rate?

Overall Rating: 3.6

Value for Cost

3.5/5Value for Cost
Return Policy

3.3/5Return Policy


Brand Highlights

  • Targets 10 types of skin-boosting collagen.
  • Visibly reduces fine lines and wrinkles in just two weeks.
  • Fades the appearance of stretch marks in just four weeks.
  • Delivers 72 hours of continuous moisture.
  • 30-Day refund policy.

Key Ingredients

  • Argireline
  • Lipoguard
  • GluCare S
  • NaturaBase
  • Pentavitin
  • Trylagen


  • Significant Reduction of the appearance of any wrinkles and fine lines.
  • It may improve skin hydration for a more supple feeling.
  • Moisture is locked in for more prolonged younger looking appearance.
  • Protection against environmental damage.
  • Appearance of age spots may be diminished.


  • No Product Details: There is no clear pricing structure detailed on the SkinFresh MD website. Additionally, there is no information provided about any product guarantees or customer satisfaction assurances.

SkinFresh MD Ingredients – Are they Safe & Effective?

Although the full ingredient list is kept fairly secret, SkinFresh MD does promote the use of certain key ingredients in their product. These include:


– This a peptide which is considered to be a topical, safe Botox alternative. Argireline targets the small lines and wrinkles which are the result of facial expressions, such as crows feet and laughter lines. When the peptide is applied to the skin, it interrupts communication between the facial muscles and nerves, relaxing the resulting lines[1].


– Lipoguard is a vitamin E enriched moisturizing agent which also acts as a barrier to protect the lubrication process of the skin. This creates firmer, softer skin which appears healthier and younger[2].


*All individuals are unique. Your results can and will vary.

GluCare S

– This is an active yeast, which encourages the skin to use its natural defense mechanisms. This enables the skin to correct the damage caused by environmental conditions and toxins. This ingredient also allows the skin to more effectively regenerate new skin cells and repair damage[3].


– This is a base ingredient which provides a white color and is not affected by heat or heat generating ingredients.


– This ingredient binds to the keratin inside the outer skin layers to encourage proper hydration of the cells. The proper moisture content of the skin is essential to not only relieve dryness but create a healthier and more youthful appearance[4].


– This ingredient encourages the skin to produce collagen. Collagen is vital for maintaining elasticity and cell structure. As we age, the natural collagen levels in the skin are depleted, which leads to sagging skin and wrinkles[5].


Q: How to Use SkinFresh MD?

A: This cream is very simple to use. It should be applied to clean skin, so you should rinse your face with warm, soapy water and pat it dry before application. Apply a small amount of the product to the face, using circular motions to ensure that the whole face is covered.

The product takes five to ten minutes to be fully absorbed, so you should leave sufficient time before applying any other skincare products or makeup.

Q: How can I order this fresh SkinFresh MD?

A: The product can be purchased directly from their official website.

Customers Reviews

but it sure did feel good on my face

I used the whole jar, it didn’t do a thing for my wrinkles, but it sure did feel good on my face. Cool and smooth feeling. I like it for that reason.
~ Linda G.

SkinFresh MD Review – Final Verdict

While SkinFresh MD may be extremely effective, the lack of information may be prohibitive for many consumers.

With very little manufacturer information and minimal product information, consumers may find other products on the market more appealing, since they are more readily available and provide quality assurances.


*All individuals are unique. Your results can and will vary.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you’ll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.

Our Top Wrinkle Cream Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned anti-aging products and anti-wrinkle creams based on the available research:

Kollagen Intensiv - Skinception | Collagen Renewal For Ageless Skin
Fills in Fine Lines*Gold Star Evidence
Diminishes Crows Feet*Gold Star Evidence
Minimizes Dark Circles*Gold Star Evidence
Evens Skin Tone*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
XYZ Smart Collagen | The Best Collagen Cream
Wrinkles Reduction*Gold Star Evidence
Improves Skin Firmness*Gold Star Evidence
Improves Skin Texture*Strong Evidence
Smart Collagen Management*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Serious Skincare Insta-Tox - Instant Wrinkle Eradicator
Decreases Sagging Skin*Gold Star Evidence
Reduces Under-eye Puffiness*Moderate Evidence
Instantly Fills Deep Lines And Wrinkles*Strong Evidence
Eliminates Crows-Feet*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for SkinFresh MD Advanced Wrinkle Moisturizer

SkinFresh MD Review – Does SkinFresh MD Skincare Actually Work?

Customer Reviews & Ratings

2.0 out of 5

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  1. Natalie Croll

    I'd rather have the wrinkles!!!
    I purchased the cream after watching a video of a woman who had used it and had miraculous results in just a minute. This is not that product. It made my face break out with one use. It’s smooth going on but it leaves this clear shiny film under your eyes. It didn’t present to me what the promotional advertisement portrayed.

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SkinFresh MD Advanced Wrinkle Moisturizer
SkinFresh MD
1.00 Fl Oz
Argireline, Lipoguard, GluCare S, NaturaBase, Pentavitin and Trylagen

5 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Wang Y, Wang M, Xiao S, Pan P, Li P, Huo J. The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study. Am J Clin Dermatol. 2013 Apr;14(2):147-53. doi: 10.1007/s40257-013-0009-9. PMID: 23417317.
[3] GluCare® S:
[4] Consumption of a diet rich in Brassica vegetables is associated with a reduced abundance of sulphate?reducing bacteria: A randomised crossover study:

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

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