Nuzena Mushroom Immunity Defense+ Review: Is it Safe to use? 

Nuzena Mushroom Immunity Defense+ is a natural supplement scientifically formulated to support both cognitive functions and immune health. Read our review to learn more.

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In This Review

Overview of Mushroom Immunity Defense +

Unfortunately, it’s common for cognitive function to start to decline as we get older. However, there are natural substances that have been proven to improve memory and other areas of cognitive performance.

Mushroom Immunity Defense + is a supplement that has been developed by healthcare professionals to improve memory, provide anti-inflammatory defense, and reduce feelings of anxiety.

In the following Mushroom Immunity Defense + review we will be taking a look at the formula, some brand highlights, and outlining how it may benefit you. We want to help you make the best decision for your health so be sure to read through to the end.

What is Mushroom Immunity Defense +?

Mushroom Immunity Defense + is a supplement that harnesses the power of potent mushrooms that have been scientifically proven to benefit the brain or immune system in some way.

This supplement was formulated by healthcare professionals and comes in capsule form so it’s easy, convenient, and quickly effective. The company that produces Mushroom Immunity Defense + also states that it will boost immune response as well.

The mushroom formula is also beneficial for inflammation in various parts of the body. Mushroom Immunity Defense + may also protect your brain cells from free radical damage and help generate new ones for sharper cognitive performance.

How Does Mushroom Immunity Defense + Rate?

Overall Rating: 4.8
Mushroom Immunity Defense +Mushroom Immunity Defense +


Value for Cost

4.7/5Value for Cost
Return Policy

4.7/5Return Policy


Brand Highlights

  • Gluten-Free formula
  • No GMOs
  • Sustainably sourced ingredients
  • Made in an FDA-registered facility
  • Free shipping on orders over $50

Key Ingredients

  • Maitake Mushroom
  • Turkey Tail Mushroom
  • Chaga
  • Royal Sun Mushroom
  • White Button Mushroom
  • Lion’s Mane


  • Excellent blend of mushrooms
  • Natural and safe formula
  • It can help improve memory
  • It can provide anti-inflammatory defense
  • Protects from free radical damage
  • Keeps brain cells healthy


  • Results may vary
  • Not all orders are eligible for free shipping

Nuzena Mushroom Immunity Defense+Nuzena Mushroom Immunity Defense+

How Does Mushroom Immunity Defense + Work?

Mushroom Immunity Defense + works through a blend of ingredients that have been studied to benefit the brain and the immune system in some way or another. For instance, a study conducted by the University of California Los Angeles found that ingesting a certain amount of mushrooms a day can prevent or at least slow cellular damage [1].

That is partly because certain types of mushrooms are rich in an amino acid known as ergothioneine [2]. This amino acid has been found to play a key role in cellular health in multiple parts of the body, including the brain.

As a result, Mushroom Immunity Defense + can help slow down the cognitive decline that is typically attributed to aging. It can also boost your immune response so your body can fight off infections and illnesses.

Mushroom Immunity Defense + Ingredients – Are They Safe & Effective?

Mushroom Immunity Defense + is loaded with mushroom extracts and devoid of any harmful stimulants. Let’s take a close look at the ingredients:

mushroom immunity defense+ ingredientsnuzena mushroom immunity defense+ingredients

Maitake Mushroom

Multiple studies have shown that Maitake mushroom supplementation is effective for boosting the immune system[3]. The National Institutes of Health found that maitake mushrooms significantly stimulated the defense reaction of the immune system. Even short-term supplementation was found to be beneficial for immune response.

Maitake mushroom has also been found to be an adaptogen – a substance that can help the brain manage stress and anxiety. As a result, taking matiake mushroom extract supplements can help lower your levels of stress which has great benefits for sleep quality, cognitive performance and general outlook.

Turkey Tail Mushroom

Turkey tail mushroom extract is another ingredient in this formula that has a beneficial impact on the immune system. The UCLA Health staff explains, “Modern research confirms that compounds found in turkey tail mushrooms affect the immune system. More precisely, they act as nonspecific immune modulators. That’s a fancy way of saying that something either stimulates or suppresses immune function in a general way. In turkey tail mushrooms, the effect is to bolster immune function.”[4]

They go on to say that turkey tail extract supplementation can even slow the progression of serious illnesses – in some cases, it may prevent certain significant illnesses in the first place.

Chaga Mushroom

Chaga has been found to provide multiple health benefits such as lowering cholesterol levels. But perhaps the most significant health benefit is the immune energy and antioxidant properties it offers.

A study conducted by the National Institutes of Health found that chaga mushroom extract supplementation was an effective and safe means of preventing serious illnesses and regulating body temperature [5].

Royal Sun Mushroom

Royal Sun mushroom has multiple health benefits. According to the National Institutes of Health, it fights both physical and emotional stress. It can also help diabetics by lowering bad cholesterol levels.

The same National Institutes of Health report cited royal sun mushroom supplementation as an effective means of enhancing immune response as well. They observed that interactions between antigen-presenting cells and effector cells is key to healthy immune response and that royal sun spurs this interaction [6].

White Button Mushroom

White Button Mushroom supplementation has been shown to decrease the antigens that can lead to certain types of cancer. As the St. John’s Cancer staff puts it, “Treatment with white button mushrooms has indicated a decrease in Prostate-specific Antigen (PSA) in about 1/3 of patients while some of them experienced durable remissions.”[7]

According to the available study data, white button mushroom extract can be especially beneficial for men who want to reduce their risk of prostate issues.

Lion’s Mane

Lion’s mane is a natural source of antioxidants and anti-inflammatory agents that can support healthy cognitive function. According to a Pubmed study, the antioxidants in lion’s mane mushroom can protect brain cells from oxidative damage and protect against neurodegenerative decline associated with age [8].

The same study found that there are long-term benefits of lion’s mane mushroom supplementation as well. For instance, long-term intake of lion’s mane mushroom or its extracts have been linked to reduced risk of developing Alzheimer’s disease. And like most of the other muschrooms in the ingredient list, it also works to boost immune strength.

Other ingredients: Black fungus extract, cordyceps, shiitake mushroom, reishi mushroom extract.

You can BUY it directly from the Official Website

Benefits of Mushroom Immunity Defense +:

Mushroom Immunity Defense + offers a range of benefits for cognitive and immune health. These include:

Improved Cognitive Function: Mushroom Immunity Defense + is formulated to enhance memory and cognitive performance. It contains a blend of mushrooms rich in nutrients like ergothioneine, which supports cellular health in the brain, slowing down age-related cognitive decline.

Immune System Support: The potent mushrooms in this supplement, such as Maitake, Turkey Tail, and Chaga, have been scientifically proven to bolster the immune system. They help your body respond effectively to infections and illnesses, potentially preventing serious health issues.

Anti-Inflammatory Defense: Mushroom Immunity Defense + is beneficial for reducing inflammation throughout the body. This can have positive effects on overall health and well-being.

Protection Against Free Radical Damage: The supplement is designed to safeguard your brain cells from free radical damage, promoting sharper cognitive function and long-term brain health.

Stress and Anxiety Reduction: Ingredients like Maitake mushroom act as adaptogens, helping manage stress and anxiety levels. Lowering stress can improve sleep quality, cognitive performance, and overall outlook.

Mushroom Immunity Defense + Review – FAQs

Q: Are there any side effects associated with Mushroom Immunity Defense +?

A: No, there are no serious side effects to be worried about. Mushroom Immunity Defense + is made from natural mushroom extracts that are sourced responsibly. But you may still want to talk to your doctor about it just in case you are allergic to some of the ingredients.

Q: Are there any discounts or offers?

A: Yes, when you subscribe to the auto-refill program you get a 15% discount which lowers the price to $38.25

Q: Who should take it?

A: Nuzena Mushroom Immunity Defense + is a suitable supplement for both men and women.

Q: Is it safe?

A: Yes. Nuzena 3rd party lab tests all of their products and manufactures them in an FDA-registered facility.

Q: Do I need a prescription for Mushroom Immunity Defense +?

A: No, there is no prescription required. Mushroom Immunity Defense + is a natural, over-the-counter supplement.

Q: How many capsules are in a bottle?

A: Each bottle of Mushroom Immunity Defense + contains 60 capsules which is about one month’s supply.

Q: How to take Mushroom Immunity Defense +?

A: You should take 2 capsules each day. For the best results, take one in the middle of the day and another in the evening. You can also ask your doctor how best to take Mushroom Immunity Defense +.

Q: When can I expect to see results?

A: Some users may see immediate results in cognitive performance but it is recommended to take Mushroom Immunity Defense + for at least 90 days.

Q: How much does Mushroom Immunity Defense + cost?

A: Each bottle of Mushroom Immunity Defense + costs $45. Orders of $50 or more are available for interest-free payment plans.

Q: What is the return policy?

A: When you buy from the official website, you get a 30-day money-back guarantee to back up your purchase.

Q: Where can I buy Mushroom Immunity Defense +?

A: You can get Mushroom Immunity Defense + on the official Nuzena website. It may also be available on 3rd party retail sites.

Safety & Side Effects

Mushroom Immunity Defense + prioritizes safety:

Natural Ingredients: It is composed of natural mushroom extracts, free from harmful stimulants or synthetic additives.

Sourced Responsibly: The ingredients are responsibly sourced to ensure quality and safety.

Third-Party Testing: Nuzena, the company behind Mushroom Immunity Defense +, conducts third-party lab tests on their products to guarantee their safety and effectiveness.

FDA-Registered Facility: The supplement is manufactured in an FDA-registered facility, adhering to strict quality and safety standards.

No Prescription Needed: Mushroom Immunity Defense + is an over-the-counter supplement and does not require a prescription.

Possible Side Effects:

While Mushroom Immunity Defense + is generally safe, it’s essential to be aware of potential side effects:

Allergies: Although the supplement is made from natural mushroom extracts, individuals with known mushroom allergies should exercise caution. Consult your doctor if you are unsure about any allergies.

Results May Vary: While many users have reported positive experiences, individual results may vary. Some individuals may experience quicker results than others, so it’s recommended to take the supplement consistently for at least 90 days.

Shipping Costs: Not all orders may qualify for free shipping, so it’s advisable to check the terms and conditions before purchasing.

Consultation: If you have any concerns about the supplement’s suitability for your specific health condition, it’s advisable to consult your healthcare professional.

What Do the Mushroom Immunity Defense + Reviews Say?

The customer feedback has been very positive. People seem to agree that Mushroom Immunity Defense + works as advertised. Here are some Mushroom Immunity Defense + reviews submitted by actual customers:

Absolutely satisfied with the results of the Mushroom Immunity Defense + supplement so far. –Janet M.

Everyone in my household has been non-stop sick this year. We have been all taking mushroom immunity for like 2 months and so far no one is sick, fingers crossed it continues like this. –Alana Karpouzes

Yay! So excited for this mushroom blend. Best ingredients in a mushroom blend I have seen yet. –Dana Sarno

Mushroom Immunity Defense + Review – Conclusion

There is no shortage of nootropic supplements on the market but Mushroom Immunity Defense + is the real deal. The Mushroom Immunity Defense + reviews from real customers have been outstanding.

It also provides you with a wealth of health benefits including improved cognitive performance, immune support, anxiety suppression and it can even help you maintain healthy cholesterol levels.

If you have been looking for a quality supplement that can protect your precious brain function, Mushroom Immunity Defense + is a great choice. Check it out today!

Where To Find It?

You can BUY it directly from the Official Website

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Mushroom Immunity Defense +

Nuzena Mushroom Immunity Defense+ Review: Is it Safe to use? 

Customer Reviews & Ratings

5.0 out of 5

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  1. Owen

    Good quality supplements
    I’m 53 and have been using and it’s been working well for me It’s a quality supplement at a reasonable price. No foul taste or smell! since I started using the Mushroom Immunity Defense +, I have been feeling better.

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Mushroom Immunity Defense +
60 Capsule
Maitake Mushroom, Turkey Tail Mushroom, Chaga, Royal Sun Mushroom, White Button Mushroom and Lion’s Mane

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    8 Sources

    We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

    [1] 7 health benefits of mushrooms:
    [2] The biology of ergothioneine, an antioxidant nutraceutical:
    [3] Immune-enhancing effects of Maitake (Grifola frondosa) and Shiitake (Lentinula edodes) extracts:
    [4] Turkey tail mushrooms act as nonspecific immune modulators:
    [5] Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice:
    [6] The Medicinal Values of Culinary-Medicinal Royal Sun Mushroom (Agaricus blazei Murrill) :
    [7] White Button Mushrooms May help in Early Stages of Prostate Cancer–a less toxic approach:
    [8] Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia:

    **This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

    *Result may vary. The information contained in this website is provided for general informational purpose. No medical claims are implied in this content, and the information herein is not intended to be used for self diagnosis or self treatment of any condition.

    *Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

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