Premier Vitality NeuroPure Review – Does It Work as Advertised?

Neuropure is an effective dietary supplement for supporting healthy nerves that elevate memory, focus, and mental clarity naturally. Read more about it.

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In This Review


This NeuroPure review aims to provide you with essential insights into the functioning of this supplement. Does NeuroPure live up to its hype? Will it help you with your neuropathy pain, or is it a waste of money? Are the ingredients high quality, and do they actually work? If you’re thinking about buying this supplement, you need to read this article before buying.

What Is Premier Vitality NeuroPure?

NeuroPure is a dietary supplement for supporting healthy nerves and reducing the risks of neuropathy. It was created by Dr. Jack and Chris Adams using ingredients from an island called Ikarian which is located in Greece. Utilizing science and nature, the NeuroPure supplement contains five powerful ingredients guaranteed to combat the effects of pain enzymes in the body which are the root cause of neuropathic pain.

How Does It Rate?

Overall Rating: 4.7
Premier Vitality NeuroPurePremier Vitality NeuroPure


Value for Cost

4.6/5Value for Cost
Return Policy

4.4/5Return Policy


Brand Highlights

  • Uses only natural ingredients
  • Made in a FDA approved facility
  • 60 day money back guarantee
  • Certified GMP

Key Ingredients

  • Prickley Pear
  • Passionflower
  • Marshmallow Root
  • Corydalis Yanhusuo
  • California Poppy Seeds.


  • It improve energy
  • It help to increased muscle strength
  • It aids in diminishing inflammation and its associated symptoms.
  • This remedy effectively addresses nerve pain and helps treat neuropathy and related issues


  • Only available online
  • No free samples

You can BUY it directly from the Official Website

How Does Premier Vitality NeuroPure Work?

NeuroPure utilizes a powerful blend of herbs, nutrients, vitamins, and minerals to address neuropathy effectively. Its primary goal is to heal the body and rebuild neural connections, providing safe relief from neuropathic pain. Research indicates that neuropathy stems from an overactive nervous system[1], leading to the production of harmful enzymes that overwhelm the nerves and cause severe pain. These toxic enzymes, including COX-2, PGE-2, and MMP-13, damage nerve endings and neurons[2], resulting in peripheral neuropathy and pain.

To combat this issue, NeuroPure’s manufacturer has identified specific ingredients from Greece that naturally support immune health and inhibit these toxic enzymes. Each NeuroPure capsule contains a precise formulation, working consistently to neutralize COX-2, PGE-2, and MMP-13 before they can inflict damage on nerve endings. Additionally, the formula helps relax both nerves and muscles throughout the body.

The primary cause of neuropathy[3] lies in the COX-2, PGE-2, and MMP-13 enzymes, and NeuroPure works to suppress the overactive nervous system[4], preventing nerve damage by eliminating these harmful enzymes. The main components of NeuroPure consist of five potent Ikarian ingredients enriched with anti-inflammatory, sedative, and antioxidant compounds.

Premier Vitality NeuroPure Ingredients – Are They Safe & Effective?

Prickly Pear: Prickly pear, also known as “barbary fig,” is a key ingredient in the formula, particularly valued for its ability to address diabetes naturally, making it a crucial starting point in tackling neuropathic pain. Additionally, this ingredient offers many other health benefits, such as aiding in treating high cholesterol levels, obesity, and hangovers. Its antiviral and anti-inflammatory properties[5] also support the immune system, helping to rid the body of harmful free radicals that can cause stress on muscles, tissues, and cells, thus promoting a sense of calmness and relief.


The inclusion of passionflower is widely appreciated in the supplement industry due to its effectiveness in combating nerve pain[6]. This botanical remedy is also known for its positive impact on stress and anxiety[7], which can otherwise overwhelm the nervous system. The calming effect of passionflower stems from its ability to increase natural GABA levels in the brain. GABA plays a vital role in calming the nervous system[8] and relaxing the mind, and current research suggests it can inhibit three enzymes (COX-2, PGE-2, and MMP-13) commonly associated with diabetic neuropathy treatment. Additionally, passionflower is often recommended for anxiety, sleep issues, and even symptoms of ADHD and menopause.

According to Dena Westphalen, PharmD, “Gamma-aminobutyric acid (GABA) is a neurotransmitter with potential benefits for overall well-being. As an inhibitory neurotransmitter, it plays a crucial role in calming and relaxing the central nervous system.” One of the significant advantages of GABA is its ability to reduce feelings of stress and anxiety, making it valuable in promoting a sense of tranquility and emotional balance. Its calming effect on the brain may also contribute to improved sleep quality and aid in reducing insomnia. Moreover, GABA’s role in stabilizing mood may have implications for mood regulation and emotional well-being.

While GABA supplements are available, incorporating foods rich in GABA, such as fermented foods and certain teas, into the diet may also be beneficial. It is important to note that individual responses to GABA may vary, and consulting with a Registered Dietitian or healthcare professional can provide personalized guidance on its use and potential benefits.

Marshmallow Root:

Derived from a demulcent plant, marshmallow root is valued for its anti-inflammatory properties, which can provide relief from inflammation [9] commonly associated with neuropathy. It aids in reducing swelling in muscles, improving mobility and healing wounds more effectively. Studies[10] have shown that marshmallow root possesses analgesic properties, making it useful for soothing topical pain and abrasions. Though its internal pain-relieving effects are not extensively researched, it has shown promise in helping with bacterial infections. Moreover, marshmallow root [11] supports digestive and urinary systems while being considered a beneficial remedy for coughs, colds, bronchitis, indigestion, stomach ulcers, and inflammation.


Sourced from Siberia and Japan, corydalis is often included in supplements for its immunity-boosting properties. Research[12] from the University of California Irvine indicates that this ingredient can alleviate pain caused by inflammation and tissue damage. In NeuroPure, corydalis is chosen for its potential to completely alleviate nerve pain. This plant’s tuber and root offer medicinal benefits and support the body in dealing with various mental issues, including mild depression, mental disorders, and emotional disturbances. Its ability to soothe severe nerve damage and limb tremors makes it a valuable addition to the formula. Notably, the effect of corydalis does not build tolerance, ensuring constant relief for consumers, with some likening its efficacy to pharmaceutical painkillers like morphine.

California Poppy Seed:

Known for its calming properties [13], California poppy seed acts as a neuron relaxant, helping consumers combat insomnia, migraines, stress, anxiety, and depression. It, too, plays a significant role in alleviating nerve pain, contributing to the overall soothing effect of the NeuroPure formula. While historically used in folk medicine, further research is needed to fully understand and verify its potential benefits, particularly in addressing soreness and exhaustion.

Verdict: The approval of the ingredients in the NeuroPure formula can be attributed to several factors. Firstly, scientific evidence plays a significant role in gaining acceptance. Many of these ingredients, such as passionflower and marshmallow root, have been subject to scientific research and clinical studies, which have demonstrated their potential health benefits. When people see credible scientific evidence supporting the effectiveness of these components, they are more likely to trust and approve of their use.

You can BUY it directly from the Official Website

NeuroPure FAQs

Q: What is NeuroPure, and how does it work?

A: : NeuroPure is a supplement designed to address neuropathy, a condition resulting from nerve damage associated with diabetes. It combines a blend of natural herbs, nutrients, vitamins, and minerals to combat neuropathy by supporting the healing of the body and reconstructing neural links. The formula works to suppress an overactive nervous system, preventing nerve damage caused by toxic enzymes (COX-2, PGE-2, and MMP-13) associated with neuropathic pain.

Q: How can NeuroPure help with diabetic neuropathy?

A: Diabetic neuropathy is nerve damage caused by elevated blood sugar levels in diabetes. NeuroPure’s natural ingredients are selected to support immune health and inhibit the toxic enzymes responsible for nerve damage. By targeting these enzymes, NeuroPure can provide relief from neuropathic pain, helping individuals manage the symptoms associated with diabetic neuropathy.

Q: What are the main ingredients in NeuroPure?

A: NeuroPure contains a precise blend of five potent Ikarian ingredients, including Prickly Pear, Passionflower, Marshmallow Root, Corydalis, and California Poppy Seed. These ingredients offer various health benefits, such as reducing inflammation, promoting relaxation, soothing nerve pain, and supporting overall immune health.

Q: Is NeuroPure safe to use?

A: Yes, NeuroPure is formulated with natural ingredients and is generally considered safe for consumption. As with any supplement, it’s recommended to follow the suggested dosage and consult with a healthcare professional, especially if you have any pre-existing medical conditions or are taking medications.

Q: How should I take NeuroPure?

A: For optimal results, take two NeuroPure capsules daily—one in the morning and one at bedtime. Consistent use of NeuroPure is essential to experience its potential benefits in managing neuropathic pain.

Q: Can NeuroPure be used for other conditions besides neuropathy?

A: While NeuroPure is primarily formulated to address neuropathy associated with diabetes, some of its ingredients, such as passionflower and California poppy seed, have been traditionally used to aid relaxation, reduce stress, and support sleep. However, it’s important to note that NeuroPure is not intended to diagnose, treat, cure, or prevent any disease, and individual results may vary.

Q: Is NeuroPure suitable for everyone?

A: Yes, it is safe for most people. However, it is recommended to consult with a healthcare professional before starting any new supplement, especially if you are pregnant, nursing, have underlying medical conditions, or are taking other medications.

Q: Where can I buy NeuroPure?

A: NeuroPure is only available through it’s official website if you purchase it from third-party websites, you run the risk of buying items that are not authentic.

Q: What are NeuroPure side effects?

A: There are no known side effects of NeuroPure.

NeuroPure Customer Reviews

Instead of getting our reviews from the official website, we like to get them from Amazon because you get a better overall picture of how the product works.

NeuroPure has over 50 ratings, with 4.6 out of 5 stars.

One top reviewer named Theresa H. States that the product is good and says,

My husband asked me to order the NeuroPure. He’s had nerve damage and had carpal tunnel surgery once. His doctor was getting ready to do the surgery again. My husband decided he wanted to try the NeoroPure first to see if it would help. He’s been quite pleased with his results and has decided not to have another surgery. He gives this product 5 stars.

A three-star reviewer named GRAZI177 states that she didn’t feel anything different and goes on to say,

Not working for me.

Another Five-star review by El Doc (The Doc) states Great and goes on to say.

Great product! It gives energy and stamina.

NEUROPURE REVIEW (Video Credit: YouTube)

Verdict: We approve of these reviews because they encompass both positive and critical experiences. In order to make a purchasing decision, it’s important to know how a product really works and if you want to spend your money on it.

NeuroPure Conclusion

NeuroPure is a supplement designed to address neuropathy associated with diabetes. It uses it’s powerful ingreduents to combat nerve damage caused by high blood sugar levels. It does this by targeting toxic enzyme which are responseible for neuropathis pain.

The formula’s main ingredients, including Prickly Pear, Passionflower, Marshmallow Root, Corydalis, and California Poppy Seed, offer additional health benefits, such as reducing inflammation, promoting relaxation, and supporting overall immune health.

While NeuroPure shows potential benefits, it is crucial to follow the recommended dosage and consult with a healthcare professional, especially if you have underlying medical conditions or are taking medications. Like any supplement, individual responses may vary, and it may not be suitable for everyone.

For those looking to manage neuropathic pain and explore a natural approach to address diabetic neuropathy, NeuroPure may offer a viable option. However, it is essential to ensure the product is obtained from reputable sources and always prioritize safety and informed decision-making when considering dietary supplements.

As with any health-related concerns, consulting with a healthcare professional remains essential for personalized guidance and appropriate management. Do you worry you are at risk for neuropathy or wonder about the symptoms or signs of it? If you answered yes to this we have the article for you. It’s titled “What Triggers Neuropathy, Everything You Need To Know.”

Where To Find It?

You can BUY it directly from the Official Website

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for NeuroPure

Premier Vitality NeuroPure Review – Does It Work as Advertised?

Customer Reviews & Ratings

5.0 out of 5

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  1. Justin C.

    NeuroPure is worth the money.
    Premier Vitality NeuroPure is really an amazing product. I purchase a pack of 3 bottles from the official website and within 3-4 weeks I see improvement in my memory. I am gonna again purchase it for the next 3 months.

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Premier Vitality
60 Capsules
Prickley Pear, Passionflower, Marshmallow Root, Corydalis Yanhusuo, and California Poppy Seeds.

13 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Costigan, M., Scholz, J., & Woolf, C. J. (2008). Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage. Annual review of neuroscience, 32, 1.
[2] 2.Ma W, Chabot JG, Vercauteren F, Quirion R. Injured nerve-derived COX2/PGE2 contributes to the maintenance of neuropathic pain in aged rats. Neurobiol Aging. 2010 Jul;31(7):1227-37. doi: 10.1016/j.neurobiolaging.2008.08.002. Epub 2008 Sep 10. PMID: 18786748. [3] Fisher, J. P., Young, C. N., & Fadel, P. J. (2009). Central Sympathetic Overactivity: Maladies and Mechanisms. Autonomic neuroscience : Basic & clinical, 148(1-2), 5.
[4] Hammi C, Yeung B. Neuropathy. [Updated 2022 Oct 15]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from:
[5] Madrigal-Santillán, E., García-Melo, F., Morales-González, J. A., Vázquez-Alvarado, P., Muñoz-Juárez, S., Zuñiga-Pérez, C., Sumaya-Martínez, M. T., Madrigal-Bujaidar, E., & Hernández-Ceruelos, A. (2013). Antioxidant and Anticlastogenic Capacity of Prickly Pear Juice. Nutrients, 5(10), 4145-4158.
[6] Janda, K., Wojtkowska, K., Jakubczyk, K., Antoniewicz, J., & Skonieczna-?ydecka, K. (2020). Passiflora incarnata in Neuropsychiatric Disorders—A Systematic Review. Nutrients, 12(12).
[7] Guerrero, F. A., & Medina, G. M. (2017). Effect of a medicinal plant (Passiflora incarnata L) on sleep. Sleep Science, 10(3), 96-100.
[8] Hepsomali, P., Groeger, J. A., Nishihira, J., & Scholey, A. (2019). Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review. Frontiers in Neuroscience, 14.
[9] Bonaterra, G. A., Bronischewski, K., Hunold, P., Schwarzbach, H., Heinrich, U., Fink, C., Aziz-Kalbhenn, H., Müller, J., & Kinscherf, R. (2019). Anti-inflammatory and Anti-oxidative Effects of Phytohustil® and Root Extract of Althaea officinalis L. on Macrophages in vitro. Frontiers in Pharmacology, 11.
[10] Banaee, M., Soleimany, V., & Haghi, B. N. (2017). Therapeutic effects of marshmallow (Althaea officinalis L.) extract on plasma biochemical parameters of common carp infected with Aeromonas hydrophila. Veterinary Research Forum, 8(2), 145-153.
[11] Forouzanfar, F., & Hosseinzadeh, H. (2018). Medicinal herbs in the treatment of neuropathic pain: A review. Iranian Journal of Basic Medical Sciences, 21(4), 347-358.
[12] Tian, B., Tian, M., & Huang, M. (2019). Advances in phytochemical and modern pharmacological research of Rhizoma Corydalis. Pharmaceutical Biology, 58(1), 265-275.
[13] Becker, A., Yamada, Y., & Sato, F. (2022). California poppy (Eschscholzia californica), the Papaveraceae golden girl model organism for evodevo and specialized metabolism. Frontiers in Plant Science, 14.

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

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