DermaFi Snake Venom Peptide Cream Review: Is It Safe and Effective?

DermaFi Snake Venom Peptide Cream is an anti-aging cream that works by numbing and freezing your facial skin and the muscles underneath it.

We independently research, review, and recommend the best products. Healthcare professionals review articles for medical accuracy. When you buy through our links, we may earn a commission. Read more about our process for evaluating brands and products.

In This Review

Overview

Aging can feel like watching time slowly take its toll. Every new wrinkle and sagging area on your face is a subtle reminder of what is changing. You’ve tried the creams, the serums, the promises in a jar, but nothing seems to truly reverse the signs of time.
We found a product that promises to help!

TL;DR

  • DermaFi Snake Venom Peptide Cream is an anti-aging moisturizer designed to reduce wrinkles and tighten the skin.
  • It features Syn-Ake, a synthetic peptide inspired by snake venom, along with Hyaluronic Acid and Palmitoyl Tripeptide-28 for added hydration.
  • The formula may provide temporary smoothing and firming effects, but lacks strong evidence for long-term wrinkle reduction.
  • Some users report mild irritation and limited visible improvement after regular use.

Enter DermaFi Snake Venom Peptide Cream. This cream claims to work from the outside in. It targets the signs of aging by using a unique blend of peptides and hydrating ingredients. It claims to reduce the appearance of wrinkles by making the skin firm and restoring its youthful glow.

This cream claims to cure anything, whether it’s fine lines or deep wrinkles. It promises to support smoother and firmer skin with just a few applications.

Could this be the solution you’ve been searching for, or another expensive talk more delivers less product? Let’s find out.

What is DermaFi Snake Venom Peptide Cream?

You read that right! Your eyes aren’t playing tricks on you! An anti-wrinkle ingredient that is taking the market by storm is Syn-ake, a topical formulation for wrinkled, mature skin developed by Pentapharm Ltd. This new proprietary ingredient takes the venom of a Temple Viper snake to mimic the effects of Botox.

Though DermaFi Snake Venom Peptide Cream gives you similar effects as a Botox, it is far less more inexpensive than Botox at $89.31. The product is also currently being offered for $4.95 if you sign up for a free trial. If you’re not satisfied with the product, you can always ship it back to the manufacturer and cancel your subscription. Just make sure that you are able to make the cancellation before the 15th day of your free trial offer, which begins on the date that you made the placement for the free trial subscription.

Otherwise, be ready to be charged with the full amount of the product, and be shipped and charged with the product every month until you call in to cancel your subscription.

How Does Though DermaFi Snake Venom Peptide Cream Rate?

Overall Rating: 3.6
DermaFi Snake Venom Peptide CreamDermaFi Snake Venom Peptide Cream

ingredient

3.7/5Ingredients
Value for Cost

3.5/5Value for Cost
Return Policy

3.3/5Return Policy
Safety

3.2/5Safety

Brand Highlights

  • Make fine lines disappear.
  • Improve in appearance by 84%.
  • Tightens pores by as much as 95%.
  • Boosts results to 73% brighter skin.
  • 30-Day refund policy.
WOWMD Anti-Aging Collection

Key Ingredients

  • Syn-Ake Peptide
  • Hyaluronic Acid
  • Palmitoyl Tripeptide-28
  • Biofill

Pros

  • Deep moisturization
  • Visibly less and improved appearance of wrinkles in just a few minutes after application
  • It may help to increase skin firmness and elasticity.
  • It may increase hydration and improve overall skin wellness.

Cons

  • Does not address long-term skin health.
  • Syn-Ake ingredient lacks long-term safety and effectiveness data.
  • Subscription model hides excessive fees and makes cancellations difficult.
  • Many users report being charged unauthorized fees after a “free trial.”
  • Company has a poor reputation with numerous customer complaints.
  • Delivers temporary wrinkle improvement results only
  • Available only via online subscription

About the Brand

DermaFi Snake Venom Peptide Cream is produced by DermaFi. The brand boasts of specializing in skincare products aimed at anti-aging and skin rejuvenation. The company focuses on using unique and advanced ingredients like Syn-Ake.

It’s a peptide inspired by snake venom to deliver temporary cosmetic benefits. DermaFi primarily sells its products online to offer them through subscription models to ensure regular delivery.

While the brand claims to use innovative ingredients for youthful skin, it has faced criticism for its business practices, including hidden fees and customer service issues, which may raise concerns for potential buyers.

How Does DermaFi Snake Venom Peptide Cream Work?

As mentioned, the primary ingredient in DermaFi Snake Venom Peptide Cream is Syn-ake. It has a relaxing effect on skin and muscles. Syn-ake relaxes, numbs and freezes your facial skin and the muscles underneath it so that your skin can be reset back to an expressionless state. In turn, this action causes your wrinkles to become stretched, seem fewer in number, and become much less visible.

Syn-ake is the unique ingredient found in DermaFi Snake Venom Peptide Cream. The anti wrinkle cream combines the snake venom with ultra hydrating ingredients that pulls up skin to make it firmer and healthier looking.

Combined with peptides and skin moisturizers, DermaFi Snake Venom Peptide Cream nourishes your skin, providing it a bigger volume of skin precursors that are required to produce and resurface younger, flawless skin, and to repair damages in the skin matrix at the same time.

DermaFi Snake Venom Peptide Cream Ingredients: Are they Safe & Effective?

The website for Dermafi Snake Venom Peptide Cream lacks transparency. It lacks a complete listing of all the ingredients used in their product. These are the ingredients that they do list:

Syn-Ake Peptide

The Syn-Ake peptide benefits the skin by temporarily relaxing facial muscles to reduce the appearance of wrinkles and fine lines. It offers a non-invasive alternative to injectables like Botox. It works by inhibiting the nerve signals that cause muscle contractions, which gives a smoother and firmer complexion, especially around the forehead and eyes.

Consistent use helps prevent new wrinkles and supports skin’s lasting collagen and elastin production. The Journal of Biomolecular Structure and Dynamics states that the Syn-Ake peptide may hold promise in anti-aging formulations with its high efficacy and safety profile.

As shared in the NouvaLift Instant Skin Wrinkle Reducer, peptides contribute to collagen production, helping diminish fine lines, improve skin texture, and create a firmer, more youthful appearance.

Hyaluronic Acid

Hyaluronic Acid naturally occurs in the skin and is vital for maintaining hydration and elasticity. It is a powerful humectant that attracts and retains moisture. This helps to keep the skin hydrated, plump, and supple.

Its production drops with age, leading to dryness and wrinkles. Topical application of hyaluronic acid can help to replenish and improve skin hydration to reduce the appearance of fine lines and wrinkles.

Furthermore, it is a major component of the skin’s extracellular matrix that improves skin firmness, resilience, and the wound healing process by promoting collagen production. The Cleveland Clinic shows the importance of hyaluronic acid through a study.

Palmitoyl Tripeptide-28

Palmitoyl tripeptide-28 promotes skin elasticity, firmness, and smoothness by stimulating the production of collagen and other extracellular matrix components.

It also helps improve skin tone and texture by reducing the appearance of fine lines and wrinkles, and can repair a damaged skin barrier. Palmitoyl tripeptide-28 is generally gentle enough for sensitive skin types.

A 2021 study published in Journal of Pharmaceuticals shows that palmitoyl tripeptide-8 significantly reduced the number of dilated capillaries and the size of dilated vessels up to 30% and 51%, respectively. Edema was also reduced by 60% due to palmitoyl tripeptide-8.

Biofill

Biofill offers several skin benefits by using the blood’s platelets and plasma to stimulate natural skin rejuvenation. It restores skin volume for a fuller appearance to smooth fine lines and wrinkles, and improve overall skin texture and tone through increased collagen and elastin production.

A 2020 study published in the Journal of Cutaneous Aesthetic Surgery states that Biofill works well for fine rhytides reduction as well as to volumize, contour, and rejuvenate the face, neck and hands.

How To Use Though DermaFi Snake Venom Peptide Cream?

Follow these easy steps for the best results from DermaFi Snake Venom Peptide Cream:

  • Start by cleansing your face thoroughly with water and your preferred cleanser to remove dirt and impurities, then pat dry.
  • Apply a generous amount of the cream to your face and neck.
  • Gently massage the cream into your skin, being careful not to move any facial muscles for at least three minutes to allow full absorption.
  • Use both morning and night for smoother and firmer skin.
  • Consistent use will help your skin appear more youthful and rejuvenated.

Benefits of Though DermaFi Snake Venom Peptide Cream

  • It Might Reduce Wrinkles : Syn-Ake mimics Botox to smooth fine lines and wrinkles.
  • Claims to Firm Skin : Its peptide content might help tighten and improve skin elasticity to offer a lifted look.
  • Claims to Boost Hydration : Hydrating ingredients like Biofill may keep the skin moisturized and plump.
  • It May Enhance Skin Radiance : The cream may promote a more youthful and glowing complexion.

Side Effects of Though DermaFi Snake Venom Peptide Cream

DermaFi Snake Venom Peptide Cream may cause mild irritation, redness, or stinging effects on sensitive skin. If these effects persist or worsen, discontinue use immediately. As with any skincare product, it’s important to perform a patch test before applying to the face to avoid adverse reactions.

Safety of Though DermaFi Snake Venom Peptide Cream

DermaFi Snake Venom Peptide Cream is intended for external use only. Perform a patch test before use to check for allergic reactions or irritation. Avoid contact with eyes and broken skin. If irritation occurs, discontinue use immediately. Consult a dermatologist if you have sensitive skin or underlying skin conditions.

Product Price of Though DermaFi Snake Venom Peptide Cream

Dermafi Snake Venom Peptide Cream is available through some independent retailers for the price given below:

  • 1 oz jar of Dermafi Snake Venom Peptide Cream: $20.00

Instead of being sold through their official website, there is an offer for a free jar instead. To get the free jar, however, you must enroll in their automatic renewal program, which many past users have complained about. There are a number of hidden fees associated with participating in the program and attempting to leave it. There are some indications that collecting those fees is a larger part of their business model than actually producing the highest quality product that they can.

WOWMD Anti-Aging Collection

Though DermaFi Snake Venom Peptide Cream Review: FAQs

Q: What is DermaFi Snake Venom Peptide Cream?

A: DermaFi Snake Venom Peptide Cream is an anti-aging skincare product designed to reduce wrinkles, firm the skin, and improve the overall appearance of your skin with a blend of peptides and hydrating ingredients.

Q: How do I use DermaFi Snake Venom Peptide Cream?

A: Cleanse and tone your face, then apply a generous amount of cream to your face and neck. Avoid moving facial muscles for at least three minutes to allow the product to fully absorb. Use twice daily for best results.

Q: Is this product suitable for all skin types?

A: DermaFi Snake Venom Peptide Cream is suitable for most skin types, but those with sensitive skin should perform a patch test before applying it to the entire face. If any irritation occurs, discontinue use.

Q: How soon can I expect to see results?

A: Results may vary depending on your skin type, but some users notice temporary improvements in skin texture, reduced appearance of wrinkles, and firmer skin after consistent use over a few weeks.

Q: Can I use this cream with other skincare products?

A: Yes, you can use DermaFi Snake Venom Peptide Cream alongside other skincare products. For best results, apply it after your toner and before your moisturizer or sunscreen.

Q: Is there a money-back guarantee?

A: The product is sold through a subscription model, and while there may be a 30-day refund policy, users are advised to read the terms and conditions carefully to understand the cancellation and refund process.

Q: Are there any side effects?

A: Some users may experience mild irritation, redness, or stinging, especially those with sensitive skin. It is recommended to perform a patch test before full application to ensure compatibility with your skin. If irritation persists, discontinue use.

Q: How Should You Use DermaFi Snake Venom Peptide Cream?

A: Use DermaFi Snake Venom Peptide Cream after cleansing your face thoroughly with water and applying toner. Apply liberally. Try not to move a facial muscle while applying the product and well into an estimated 3 minutes.

Q: What are the Precautions When Using This Supplement?

A: For external use only.
Some product ingredients may be irritating to the skin. Always perform a patch test to check for allergic reactions to the product or any of its components.

Q: Who can use DermaFi Snake Venom Peptide Cream?

A: Women and men in their 30s and beyond who want to see a younger version of them everyday should use DermaFi Snake Venom Peptide Cream.

What Do the DermaFi Snake Venom Peptide Cream Customers Reviews Says?

DON’T BUY THIS!! The company is a total SCAM. THEY WILL CHARGE YOUR credit card WITHOUT YOU AUTHORIZING IT & YOU WILL NOT BE ABLE TO GET YOUR $$ BACK. You call the 1-844-965-8696 and they will not let you speak to a supervisor and then THEY HANG UP ON YOU. Best thing to do is change your credit card # with your bank QUICK!! (free from banks)~ JJ

The bank says you have to cancel with Dermafi. Dermafi is allowed to roll the charges onto your new card. ~ Anonymous says

Do Not fall for this scam product!!! Wheh you sign up for this *free sample* They keep charging you $90 per month!!!! I moved & never received any of these…but got chatged Beware…dont sign up for a *free sample*….only pay shipping!!!!~ Kathy

SO TRUE!!!! BEWARE!! ~ Kathy

AGREE!!!!DONT BUY THIS PRODUCT!!! That’s exactly what happened to me and I did get a new credit card because they told me twice they would not send anymore and we’re sorry and then I got another bottle and another BIG charge. This is a scam for your MONEY. I threw my bottles in the TRASH!!!!!!!! Don’t BUY!! WARNING~ Angels

Scam. I cancelled and they kept charging me.”~ Anonymous

AVOID THESE COMPANIES AT ALL COST. TOTAL FRAUD AND THEY WILL STEAL YOUR MONEY, WONT REFUND IT, WILL DRAG OUT PHONE CALL FOR AN HOUR AND THEN HANG UP ON YOU. TOTAL SCAM, DONT FALL FOR IT.~J HALES

TOTALLY SCAMMED. I NEVER SIGNED FOR MORE THAN THE SAMPLE. WHEN I SAW THE PRICE, SAID NO WAY. FOUGHT TO GET REFUND AND THEN THEY SENT ME ANOTHER SAMPLE. BEFORE I COULD EVEN CALL THEM AGAIN, THEY BILLED ME FOR A FULL ORDER AND SAID, WELL ITS ALREADY IN THE MAIL..THE SAGA GOES ON….~ Linda Crowley

DermaFi Snake Venom Peptide Cream Review: Conclusion

Everybody has problems with their skin – too oily, too dull, hyperpigmented, too dry, too dark, too many freckles, to name a handful. What’s your skin issue?

When people reach their 30s and beyond though, women and men, all of a sudden, have the same skin issues they face: wrinkles, fine lines, sagging skin. All of which, signs of skin aging that are inevitably going to happen anyway but, if you’re getting yours too soon, it’s not just your fortune but, there must be something really wrong or really lacking in your skincare routine.

Aging requires several changes, a total lifestyle revamp. When it comes to your skin, it requires completely ditching what you think you’ve always known about skincare so that you can be prepared to fully embrace a newer anti-aging skincare routine that best fits your mature skin, even when that means signing up for snake venom.

DermaFi Snake Venom Peptide Cream offers a new anti-wrinkle cream technology which, nobody can dispute at the moment, might just be able to deliver the results you want to see and feel. If you haven’t already found the best anti wrinkle cream that matches your skin, this might be worth trying out.

Rating
Our Top Peptide Moisturizer Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned peptide moisturizer based on the available research:

WOWMD Peptide Moisturizer
Seal
Prevents Premature Aging*Gold Star Evidence
Reduces Fine Lines & Wrinkles*Gold Star Evidence
Promotes Comfort & Hydration*Gold Star Evidence
Provides Antioxidant ProtectionStrong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

1
Customer Reviews for DermaFi Snake Venom Peptide Cream

DermaFi Snake Venom Peptide Cream Review: Is It Safe and Effective?

Customer Reviews & Ratings

3.0 out of 5

Review this Product

Leave a review and share your experience with others.

Write a Review

  1. Michael Jordan




    It doesn't do anything worth the cost
    Another expensive facial product that we pay for, in hopes of a noticeable benefit to our skin’s health in someway. It did absolutely nothing. Double your cost and pay for Alastin or Zo SKin…at least your skin benefits from overpaying. Not a terrible product, didn’t do anything bad per say.

Write a Review

Your email address will not be published. Required fields are marked *

5000 characters remaining.

Explanation ?

Privacy Policy

Submitting this review means that you agree to our Review Guidelines, confirming that you are a verified customer who has purchased the product and may have used the merchandise or experienced the service, and providing only a real interaction and experience without ulterior motives or has an affiliate or business with the company in any way. By ticking this box and submitting this review, you also accept that submitting fake reviews is a violation of Consumer Health Digest’s Terms of Use and such conduct will not be tolerated.

X

How to Upload your Proof of Purchase:

Please follow the instructions listed below to upload your electronic proof of purchase.

  • To upload your physical paper receipt, simply take a picture of it with your camera or phone. You may also try taking a still picture of it with your computer’s webcam.
  • Once you have taken the picture, save the image as a JPG, TIF, or PDF file.
  • Please note that you cannot upload a file that is larger than 2MB.
  • Then all you have to do is click the Browse button and search for your receipt picture file. You can also drag and drop the file into the provided field.

If you are still not able to upload your proof of purchase, please contact us for further assistance (take a moment to look over the sample bill below).

proofimg

Have a Question? Please Tell Us What We Are Missing Here!

Note: Consumer Health Digest isn't a healthcare provider. We can't respond to health questions or give you medical advice.
Your Privacy is important to us.
PRODUCT NAME
DermaFi Snake Venom Peptide Cream
PRODUCT BRAND
Pentapharm Ltd
PRICE (in USD)
$20
ITEM FORM
Cream
VOLUME
1.00 Fl Oz
INGREDIENTS
Syn-Ake Peptide, Hyaluronic Acid, Palmitoyl Tripeptide-28, Biofill

Upload Your Video Review

    Privacy Policy

    Submitting this review means that you agree to our Review Guidelines, confirming that you are a verified customer who has purchased the product and may have used the merchandise or experienced the service, and providing only a real interaction and experience without ulterior motives or has an affiliate or business with the company in any way. By ticking this box and submitting this review, you also accept that submitting fake reviews is a violation of Consumer Health Digest’s Terms of Use and such conduct will not be tolerated.

    How to record video?

    • Prepare your device, ensuring it's charged and has enough storage.
    • Find a quiet, well-lit space with natural or good indoor lighting.
    • Position your device and frame yourself in the center with head and shoulders visible.
    • Introduce yourself, the product, and why you chose it.
    • Share your experience, including positives, negatives, and recommendations.
    • Test audio and video to ensure they're working properly.
    • Keep the video concise, aiming for 1-3 minutes.
    • Review your recording for quality and clarity.
    • Upload your video.
    Note: Video should be recorded in single take only (without any cuts)

    Video recording details:

    • Video duration: 1 - 3 minutes
    • Video Quality: Full HD (1080p and above)
    • Video format: MP4
    • Audio Quality: Clear without background noise

    4 Sources

    We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

    [1] Anti-aging activity of Syn-Ake peptide by in silico approaches and in vitro tests : https://pubmed.ncbi.nlm.nih.gov/37349941/
    [2] Hyaluronic Acid : https://my.clevelandclinic.org/health/articles/22915-hyaluronic-acid?
    [3] Usage of Synthetic Peptides in Cosmetics for Sensitive Skin : https://pmc.ncbi.nlm.nih.gov/articles/PMC8400021/?
    [4] Bio-Filler: An Effective Facial Rejuvenation Tool—Easy on Pocket : https://pmc.ncbi.nlm.nih.gov/articles/PMC7646418/?

    **This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

    *Result may vary. The information contained in this website is provided for general informational purpose. No medical claims are implied in this content, and the information herein is not intended to be used for self diagnosis or self treatment of any condition.

    *Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

    email img
    1. About Us
    2. Editorial Policy
    3. DMCA Policy

    Note: Results may vary about any product effectiveness. The information contained in this website is provided for general informational purposes only. No medical claims are implied in this content, and the information herein is not intended be used for self-diagnosis or self-treatment of any condition.

    3 E Evergreen Road, Suite 101, New City, NY 10956, United States
    staff@consumerhealthdigest.com
    USA/Canada Toll Free: 1 (866) 884-2527

    Disclaimer: The information provided on this site is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions. You should not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Your use of this website indicates your agreement to this websites published terms of use and all site policies. Please see our Medical Disclaimer for more information.

    Any use of this site constitutes your agreement to the Terms of Use and Privacy Policy mentioned here.

    Do Not Sell My Personal Information

    Helping the Cause

    Make a Donation

    Follow Us

    google-preferred-source

    Ensure you see our latest reviews in Google Top Stories — add Consumer Health Digest as a Preferred Source with one click.

    X

    Advertising Disclosure

    The content that appears on this page is presented as an overview vs. comparative marketing. The provided information includes product information, overviews, buying guides, and product specifications. All trademarks, registered trademarks and service-marks mentioned on this site are the property of their respective owners. If something is factually inaccurate please contact us and let us know. By contributing your product facts helps to better serve our readers and the accuracy of the content.

    The table below does not include all companies or all available products in the market but those that we promote as their affiliates. In full compliance with the FTC guidelines, please assume that any and all links on the table are affiliate links, and we may receive compensation if you click one of these and make a purchase. We are independently owned and the opinions expressed here are our own. All editorial content is written without prejudice or bias, regardless of sponsor or affiliate associations. Read more about our process.
    X