Plenity Reviews – Does Plenity Really Work for Weight Loss?

Plenity is the only FDA-cleared weight management approach made from naturally derived building blocks—cellulose and citric acid. Is It Safe? Read More about Plenity Reviews and Plenity weight loss results here.

In This Review

What is Plenity?

Plenity is a hydrogel weight loss product that uses cellulose and citric acid to fill your stomach, curbing your appetite so you eat smaller meals. This is a product which you can only get by meeting with an online physician and getting a prescription first.

It’s a safe product that the FDA has approved for weight-loss purposes. There’s an online community you can join to get support and information during your weight loss journey.


Who is the Manufacturer of Plenity?

A company by the name of Gelesis, Inc. manufactures and sells Plenity Weight Loss Pills. It started in 2006, and they have its headquarters in Boston, Massachusetts. Their parent company is PureTech Health. Gelesis, Inc is a biotechnology company that produces products and technology to help treat obesity.

How Does Plenity Work?

Plenity weight loss supplement primarily contains cellulose and citric acid in capsules, and the user is meant to take them with a lot of water 20 minutes before a meal. In the stomach, the outer part of the capsule dissolves, releasing the ingredients. The particles absorb the water around them and grow much bigger than they were initially.

This creates individual pieces which are firm. They fill your stomach so you feel less hungry, and you consume less during your meal. When the particles get to the large intestine, they break down, and the water releases. It all leaves your body when you go to the bathroom. Ideally, Plenity results in weight loss.

In addition, citric acid can speed up the metabolism, which puts the body into a state of thermogenesis where it burns fat rapidly. This can help you lose weight faster.

A clinical study published in Clinical Diabetes[1] by the American Diabetes Association concluded that Plenity was a safe and effective weight loss method. Another study in the Annals of Pharmacotherapy[2] says it’s a non-systemic approach to weight loss for people with obesity, and a good alternative to current pharmacological solutions.

Plenity Ingredients – Are They Safe and Effective?

When looking at Plenity reviews, it is important to scrutinize the ingredients within its formula.

Cellulose – This is a molecule that makes up the walls of plant cells. It contains hydrogen, carbon, and oxygen atoms. It seems like an ideal weight-loss ingredient because it expands inside the stomach, making you feel full.

However, the research is not completely certain about cellulose as a weight loss agent. A study published in Obesity[3] found that it did not affect appetite.


*All individuals are unique. Your results can and will vary.

Citric Acid – This is an organic acid which is found in citrus fruits. It’s often included in nutritional supplements as an additive ingredient.

It’s a potent antioxidant that can help speed up metabolism, leading to fat and weight loss. According to Science Direct[4], research shows that hydroxycitric acid can reduce appetite, and weight, and improve the lipid profile.

What are the Pros of Plenity?

  • Plenity may suppress your appetite, so you eat less.
  • The FDA has approved this supplement.
  • Plenity Pill could help you lose weight.
  • Its efficacy has been confirmed in clinical trials.
  • There’s an online community to provide support.

What are the Cons of Plenity?

  • Plenity Diet Pill is an expensive weight loss aid.
  • You need a prescription to get the product.
  • There may be side effects like gas and bloating.

Warnings & Precautions

Before taking any supplement, you should read warnings and safety information carefully. The manufacturer of Plenity has provided all the information on how you should take Plenity weight loss pills.

Plenity Warnings and Precautions

Plenity Warnings and Precautions

Plenity FAQ

Q: How Should You Take Plenity?

A: The recommended dosage is six capsules per day. Take three capsules 20 minutes before lunch and three more 20 minutes before dinner. Drink 16 ounces of water after you take the Plenity pills, as you need this for the product to work. Do not take more than the amount recommended by the manufacturer.

Q: Is Plenity FDA Approved?

A: Plenity is a safe diet pill that has been approved by the FDA. It can help you manage your weight when combined with a good diet and exercise. It acts in your stomach to make you feel full, allowing you to eat less during the day.

Q: How much is Plenity weight loss?

A: You can get this product through the official website and another site called Push Health. However, in order to get the Plenity pills, you have to see a doctor online and get a prescription first. On the official site, the Plenity cost is $98 for a 4-week supply. This works out to $1.75 per meal.

Q: What is Plenity’s Return Policy?

A: There are no returns for this product because they do not offer a return policy for prescription products. All sales are final, so make sure this is the right supplement for you before you buy.

Q: Does Plenity Offer a Free Trial?

A: There is no free trial associated with this product. You buy it through the official or another site by meeting with a doctor and getting a prescription; then you purchase it. There are no free samples or trial bottles.

Q: What Do the Plenity Reviews Say?

A: Most of the Plenity weight loss reviews are on the manufacturer’s official website, many in the form of video testimonials. Most of these reviews were very positive and spoke about the success stories of the great weight loss people experienced without any side effects after using this product. They mentioned losing weight without feeling deprived or hungry. There were no negative Plenity reviews found on the official site.


*All individuals are unique. Your results can and will vary.

Q: Does Plenity Have Any Side Effects?

A: In a clinical study reported by the manufacturer, users got no more Plenity side effects than the subjects taking a placebo. Based on Plenity reviews, common symptoms included bloating gas or abdominal pain. There were no serious side effects reported for this product.

Q: Who Should Use Plenity?

A: Plenity is designed for people who are overweight or obese and have a BMI of 25 to 40 kg/m2. It aims to suppress appetite and help people eat less, which speeds up their weight loss efforts. Users should follow a healthy diet and exercise regularly while using the product.

Q: Is Plenity Covered by Insurance?

A: Yes, you should be entitled to exclude any more of your Plenity out-of-pocket costs from your HSA (Health Savings Account), FSA (Flexible Spending Account), or MSA (Medical Savings Account).

Q: Where Can I Get Plenity?

A: Plenity availability is only on its official website and not in pharmacies, as it has been licensed by the FDA. We encourage you to revisit this page because medicines can be licensed days, weeks, or months before they are published.

Q: Is Plenity Safe?

A: Plenity is a weight-loss supplement formulated with two natural ingredients: cellulose and citric acid, which has been approved by the FDA. Plenity users lost an average of 10% of their body weight after six months without experiencing any side effects in a clinical trial.

Q: How can I get Plenity prescription?

A: You do not need to meet with a physician in person to get Plenity weight loss pills! You can visit to start an online consultation, where you’ll be asked to share your medical history and answer general health questions with a licensed physician.

Q: How to cancel Plenity subscription?

A: Plenity’s official website does not provide a refund policy. However, if you have any questions about the cancellation of a product, contact them via

Email or call or text 424-347-6299 (Mon–Fri: 9:30am–9pm EST).

Plenity Review – Final Verdict

Plenity is a weight loss product that uses bioactive technology to make you feel less hungry during a meal, so you consume less. This is a prescription product, and you must meet with a doctor before you can take it. You can also join the online community, which provides you with ongoing support.

Looking at the official website, almost every Plenity review raved about the great weight loss benefits of this product. Many users said it made their journey that much easier and that they never felt hungry. There were a few poor reviews on the official site, if any at all. On Plenity’s official website, you can see more before and after testimonials.

Plenity Review – Before and After (Video Credit: YouTube)

This product has been clinically tested and shown to be safe; however, there are some mild digestive symptoms that could occur. If you experience any Plenity side effects that seem more serious, stop using the product. Before you use this supplement, see an online doctor and also your own doctor to get medical approval.

Below you'll find some of the most effective weight loss supplements on the market today, in our opinion.

Our Top Rated Weight Loss Supplement

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned diet pills and weight loss supplements based on the available research:

PhenQ | Best All-Natural Advanced Weight Loss Aid
Helps in Boosting Metabolism*Gold Star Evidence
Revitalizes Energy & Mood*Gold Star Evidence
Assists in Fat Block & Burn*Strong Evidence
Aids in Appetite Control*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
MCT Wellness | Natural Weight Loss System
Support Healthy Metabolism*Gold Star Evidence
Boost Energy and Vitality*Strong Evidence
Support Brain Health*Strong Evidence
Help Reducing Gas, Bloating*Moderate Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Nucific Bio X4 | Best Weight Management Probiotic
Promotes Weight Management*Gold Star Evidence
Manages Junk Cravings*Strong Evidence
Boosts Metabolism*Strong Evidence
Supports Smoother Digestion*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Active PK | Best Abdominal Fat Remover
Help Combat Abdominal Fat*Gold Star Evidence
Help Minimize Cravings*Strong Evidence
Boost Natural Energy*Strong Evidence
Promote Clearer Thinking*Moderate Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.7
Phen24 | Best Weight-Loss Solution
Improves Metabolism*Gold Star Evidence
Curbs Cravings*Strong Evidence
Suppresses Appetite*Strong Evidence
Promote Healthy Sleep*Moderate Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.7
Green Coffee Plus | Premium Green Coffee Bean Extract
Antioxidant Support*Gold Star Evidence
Increases Metabolism*Strong Evidence
Boost Energy Levels*Strong Evidence
Helps Support Weight Loss*Moderate Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.7

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Plenity

Plenity Reviews – Does Plenity Really Work for Weight Loss?

Customer Reviews & Ratings

3.2 out of 5

Review this Product

Leave a review and share your experience with others.

Write a Review

  1. Lauren

    Lost over 30 pounds in a few months, love it!
    I lost over 30 pounds in a few months and inches off my waist and hips. It took a few weeks until my brain understood the feeling of ‘full’ which is not a stuffed turkey feeling but more just a satisfaction. Plenity also helps me with in-between meal cravings. I love this product.
  2. Catherine Harvey

    Losing weight with Plenity is too fast
    I like Plenity but have irregular bowel movements, mostly at night. I can’t eat very much, or I will be sitting on the toilet for a while. I also take other medications: Seroquel, Zoloft, Plenity, and Oxybutynin.

    I started July 6, and as of today (July 23), I have lost 10 pounds. I don’t know if that is too fast. I have headaches. I have stomach cramps after I eat. I have to be very deliberate about food. I can’t eat greasy or heavy foods. I have been sticking to salads and grapefruit.

    I am otherwise reasonably healthy besides wanting to lose weight. My family has diabetes problems. The only thing that I have to avoid is milk.

  3. Phyllis Vallario

    Plenity Package Lost
    I was supposed to receive my Plenity package on 6/17/2022. MAiled via UPS, tracking number is 1Z8249XA0391050466. I have tried multiple times to place a claim with UPS and they have not been at all helpful. I tried to place the claim via customer service and no one ever picked up after being on hold for 45 minutes. I tried to place a claim online and it would not take my information, saying it was invalid. Can you please help me?
  4. Melanie Oliverius

    I don't feel full
    Well, I foolishly ordered 3 months worth to get the discount and I fear I wasted $200. I have taken Plenity for 4 days and after guzzling a 16oz water with my 3 large caplets I don’t feel any fuller than if I drank a bottle of water. Kicking myself for suckered into the t.v. ad and believing bcuz it was a prescription that it must work.
  5. Ashley

    Full before meals!
    I have used Plenty for a short time – however, it is amazing. I take the 3 pills with 16 – 20 oz of water about 30 minutes before my lunch and dinner. It fills me up which has me eating less. This product is great for individuals that tend to over-eat!!!

Write a Review

Your email address will not be published.

5000 characters remaining.

Explanation ?

Privacy Policy

Submitting this review means that you agree to our Review Guidelines, confirming that you are a verified customer who has purchased the product and may have used the merchandise or experienced the service, and providing only a real interaction and experience without ulterior motives or has an affiliate or business with the company in any way. By ticking this box and submitting this review, you also accept that submitting fake reviews is a violation of Consumer Health Digest’s Terms of Use and such conduct will not be tolerated.


How to Upload your Proof of Purchase:

Please follow the instructions listed below to upload your electronic proof of purchase.

  • To upload your physical paper receipt, simply take a picture of it with your camera or phone. You may also try taking a still picture of it with your computer’s webcam.
  • Once you have taken the picture, save the image as a JPG, TIF, or PDF file.
  • Please note that you cannot upload a file that is larger than 2MB.
  • Then all you have to do is click the Browse button and search for your receipt picture file. You can also drag and drop the file into the provided field.

If you are still not able to upload your proof of purchase, please contact us for further assistance (take a moment to look over the sample bill below).


Plenity Ques and Ans

  • Q: Does anyone get bothered by irregular bowel movements in the first month of taking Plenity?

    A: According to Plenity reviews, people get bloated gas or abdominal pain when they start taking the supplement.

  • Q: What is the cost of the televisit to get this product?

    A: A four-week supply of Plenity costs $98 ($1.75 per meal). You may also save 15% on a 12-week supply by purchasing it for $249. You can begin a plenity telehealth session.

  • Q: When I asked my g.p. about this product he showed me that his computer that this product can be purchased across the counter, therefore he could not write a script for this/ Is this correct information, or does the product have another name?

    A: The name of the product as shown on the official website is Plenity. It can be purchased through the official website as well as from another site called Push Health.

Have a Question? Please Tell Us What We Are Missing Here!

Note: Consumer Health Digest isn't a healthcare provider. We can't respond to health questions or give you medical advice.
Your Privacy is important to us.
60 capsules
Cellulose, Citric Acid


We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Plenity (Oral Superabsorbent Hydrogel).
[2] Oral Superabsorbent Hydrogel (Plenity) for Weight Management.
[3] Effect of a Cellulose-containing Weight-loss Supplement on Gastric Emptying and Sensory Functions.
[4] Hydroxycitric Acid U121 for improving hydroxycitric acid production, and Sorangium cellulosum for improving production of epothilones.

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

  1. About Us
  2. Editorial Policy
  3. DMCA Policy

Note: Results may vary about any product effectiveness. The information contained in this website is provided for general informational purposes only. No medical claims are implied in this content, and the information herein is not intended be used for self-diagnosis or self-treatment of any condition.

3 E Evergreen Road #1193, New City, NY 10956
Phone: +91-712-2543006

Disclaimer: The information provided on this site is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions. You should not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Your use of this website indicates your agreement to this websites published terms of use and all site policies. Please see our Medical Disclaimer for more information.

Any use of this site constitutes your agreement to the Terms of Use and Privacy Policy mentioned here.

Do Not Sell My Personal Information

Helping the Cause

Make a Donation

Follow Us


Advertising Disclosure

The content that appears on this page is presented as an overview vs. comparative marketing. The provided information includes product information, overviews, buying guides, and product specifications. All trademarks, registered trademarks and service-marks mentioned on this site are the property of their respective owners. If something is factually inaccurate please contact us and let us know. By contributing your product facts helps to better serve our readers and the accuracy of the content.

The table below does not include all companies or all available products in the market but those that we promote as their affiliates. In full compliance with the FTC guidelines, please assume that any and all links on the table are affiliate links, and we may receive compensation if you click one of these and make a purchase. We are independently owned and the opinions expressed here are our own. All editorial content is written without prejudice or bias, regardless of sponsor or affiliate associations.