Nucific Bio X4 Review – Does Bio X4 Work and Is It Safe To Use?

On this honest review, we'll dive deep into the realities of this probiotic supplement. Does Bio X4 really work? Let's find out here!
Ask A QuestionAsk A Question

In This Article

What is Nucific BIO X4?

BIO X4 is a nutritional supplement that is designed to help one in weight loss management. Thus, it may assist you in achieving your desired goals and help you live a healthier life.

It’s a product that can help reduce appetite to theoretically consume fewer calories and thus minimize weight gain.


Nucific BIO X4 may support digestive health and assist in weight management.

Who is the Manufacturer Nucific Bio X4?

Bio X4 is manufactured by a company named ‘Nucific’ that is based out of California[1].

It is a relatively new product, but the manufacturer’s website is professional and comprehensive and positions itself as having the overall mission of improving health and helping people always feel their best through products with ingredients to support nutritional deficiencies.

Consistent with that intent for good health is concern over the health of the environment and so the product packaging is also earth-friendly.

You can BUY it directly from the Official Website

How Does Nucific Bio X4 Work?

BIO-X4 ensures that you stay in great shape, while the weight loss supplement works on reducing your waistline.

The product contains a wide array of fat-loss and digestive enhancers, including:

Caralluma Fimbriata – may work to control hunger and cravings[2]. A study published in the Journal Perspectives in Clinical Research explored the link among Caralluma fimbriata and weight loss.

Epigallocatechin gallate (EGCG) – can improves the rate of fat loss[3] and weight reduction.

BIO-X4 pairs these two with various digestive enzymes and probiotics that will help ensure that the rate of weight loss that you experience is optimal.

BIO-X4 may keep the energy up and hunger down, meaning that you will be able to burn much more fats than you take in.

According to the study in the Journal Nutrients, probiotics may help rebuild “good” bacteria in your body and support bacteria levels.

Some users of BIO-X4 have already reported seeing:

  • Reduced cravings for unhealthy junk food
  • Increased energy levels throughout the day
  • Improved levels of weight loss
  • An absence of gas, irregular visits to the bathroom and bloating

The manufacturer also claims that this product does not contain gluten, lactose or fillers and thus those who are allergic to these ingredients should use it comfortably as it will not cause any side effects on their bodies.

The nutrients contained are intended to accomplish this and suppress cravings for food.

The underlying rationale for the development was the recognition that people seldom get the absolute best nutrients on a daily basis from food and yet the body needs the absolute best to always operate at peak performance.

Nucific Bio X4 Ingredients – Are they Safe & Effective?

Nucific Bio X4 contains a host of ingredients considered beneficial for ultimate digestive support and management.

It contains a collection of vitamins, minerals, amino acids and herbs that help to promote bowel regularity and support immune health[4].

It can generally help you in losing your weight and works through the following ingredients:

  • Weight management blend – This contains 100mg of green tea extract[5] which has Epigallocatechin gallate (EGCG) as the main component. This may increase metabolism that stimulates weight loss in the body.
  • Probiotic blend – It’s made up of Lactobacillus blend Lacidophius , Larhamnosus, Lplantarum Bifidobacterium lactis and B animals.Nucific Bio X4 has 4 billion CFU per capsule. It can be used to treat uncomfortable bowel syndrome and other allergic reactions. It may also boosts the immunity level.
  • Craving control blend – 166mg of Caralluma Fimbriata Extract is an appetite suppressant[6]. It can be safe to use for reducing body weight as it attempts to fool the brain into believing that the stomach is loaded, even when he has not eaten anything.
  • Digestive Enzyme Blend – 88mg and has Amylase from Aspergillus Oryzae, Bromelain, and Lipase from Rhizopusorzae. Amylase is an enzyme that can catalyze the transformation of starch to sugars whereas Bromelain is found in pineapple stem and it’s an enzyme that minimizes inflammation either from injury or surgery. Lipase may help in the hydrolysis of lipids[7].
SEE ALSOProvitalize and LumaSlim

What are the Advantages of Nucific Bio X4?

  • It does not contain lactose, fillers or gluten and thus it will not cause any allergic reactions on your body. The ingredients are 100 percent pure according to the manufacturer claims.
  • Money back guarantee within 90days. If the product does not give you the desired results you can return it to the manufacturer and get the refund of your money.
  • The packaging of this appetite suppressant supplement is environmentally friendly and hence it can not cause any detrimental effects to nature.
  • Nucific Bio X4 is clinically tested by third-party labs and hence it will help you in reducing weight with no irritation on your body.
  • There is transparency about the company’s board members and their credentials.
  • There is a blog on a website that is offering overall health information about this product thus if you have any query about this product it will be well addressed.
  • The manufacturer offers free shipping of the product.

What are the Disadvantages of Nucific Bio X4?

  • For better results you would still have to put in a lot of work and maintain a proper diet.

Is Nucific Bio X4 Safe to Use?

Nucific BIO X4 is a probiotic-based nutritional weight loss product.

It seems to be safe and effective in use, according to the manufacturer claims. However, it is crucial that probiotics are associated with unwanted effects such as gas[8], bloating and nausea.

This can disappear after a few days of usage of this product. This type of problem due to probiotic supplements is not common in all. The severity of these symptoms varies from individual to individual.

It is mostly seen that people with sensitivities in the gastrointestinal tracts face these symptoms.

CAUTION: This product contains green tea that has caffeine and hence it may have allergic reactions to people who are sensitive to caffeine and other stimulants.

YOU MAY ALSO LIKEPlexus Slim and Active-PK

Nucific Bio X4 Questions and Answers

Q: What quantities of bottles adviced to order?

A: It is advised to order 6 bottles order.

Q: Does Bio X4 work if you have an ileostomy?

A: Bio X4 Probiotics are considered generally safe to consume but may cause bacteria-host interactions and unwanted side effects in rare cases. There have been many studies done on the effects of probiotics and the results vary. Some believe that more research is necessary. There is evidence that using probiotics at the same time as antibiotics, reduces the chance of diarrhea and infections. Further, it is shown the probiotics can be beneficial during diarrhea, but also with chronic constipation.

Q: Does it have any Side Effects?

A: According to the manufacturer’s claim, BIO X4 is free of any side effects. It is formed of pure elements. You can take them with your diet restrictions as it is gluten-free, allergen-free capsules.

Q: Can people with Type 2 diabetes take Bio-X4?

A: Not surprisingly, there are many types of probiotics supplements available, one of them is BioX4. Supplements may contain just one strain of probiotic, or they may multiple strains. Common strains of probiotics include the Lactobacillus, Bifidobacteria, Saccharomyces boulardii, and Bacillus coagulans. It’s a good idea to check with your doctor before taking a probiotic supplement. Some people should not take them, including people who have an overgrowth of yeast, small intestine bacterial overgrowth, or a compromised immune system.

Q: How to take BIO X4?

A: Take 1 capsule of BIO X4 with every 3-time meal. Supplementing each meal with digestive helps to process your food, obtaining the maximum amount of nutrients.

Q: What if you forgot to take BIO X4 a day?

A: If it happens to miss a dose for a whole day, just proceed as normal the other days. It can allow the body to build up the best level of enzymes, nutrients, and beneficial bacteria.

Q: How much time it will take to see results?

A: Each and every person has a different digestive system. It is advised that it takes a minimum of 60 days to fully get to work. Also, it has a 90-days money back guarantee.

Q: What is the telephone number for me to order and speak to some one. The number I have is wrong

A: You may contact them by calling on the number available on the official website. (888) 679-5520

Q: Is BIO X4 is available in stores?

A: No, you won’t find it in the stores. You can purchase it from its official website. Bio X4 is available to purchase from Nucific’s website, with a 30-day supply of 90 capsules costing $99 (equating to $1.10 per capsule).

Some other options to try for efficient weight loss are Synedrex and Zuccarin.

Q: Bio X4 Costs – How much is it?

A: A bottle of Bio X4 contains 90 capsules, and you can buy it from Bio X4 official website. The website offers you different offers that will also help you save money on a purchase. A bottle of Bio X4 costs $99. However, if you buy Bio X4 today, the company is offering a great discount on the product.

Bio X4 Review – Final Verdict

BIO X4 contains a lot of ingredients that claim to help provide digestive support, suppress appetite, and support immune health.

As said early, that BIO X4 is a new product (at the time of our research) since manufacture Nucific’s URL was registered in April 2015 and the company’s trademark was filed in June of 2015.

Although, this product seems to be safe and the choice is left to the consumer whether to buy it or not to buy.

Disclaimer: **Results may vary based on individual users and are not guaranteed. Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Where To Find It?

You can BUY it directly from the Official Website

Customer Reviews for Bio X4

Nucific Bio X4 Review – Does Bio X4 Work and Is It Safe To Use?

Average Customer Rating

out of 5

Customer Reviews

What do you think what we are missing? Leave a review and share your experience with others.

Ask A QuestionAsk A Question
Write A Review

  1. Steve


    BIO X4 - wouldn't miss a day of taking it!
    March 26, 2020, I weighed 235lbs, was diagnosed pre-diabetic, had high blood pressure and high cholesterol. The CV-19 Pandemic was in its’ early stages in the US. My Dr. was concerned about my current state of health status; and noted, my three outstanding health issues were all high-risk diagnoses’ that could easily become severely complicated and have detrimental effects on my overall well-being if I were to contract the CV-19 virus. I immediately began a diabetic diet, started light exercising (walking). I watched a Dr. Amy Lee – Nucific infomercial on Youtube about the benefits of probiotics and gut health and learned about her BIO X4 product, and ordered 3 bottles, and began taking BIO X4 on a daily basis.

    Fast forward five months (March 26, 2020, to September 1, 2020) I was officially down from 235lbs to 170lbs. 65 lbs gone! My A1c dropped considerably, my blood pressure had stabilized and my cholesterol changed for the better. I was truly on a path to healthfulness. My gut health has increased tremendously, it’s May 2021 and I weigh 150lbs. I maintain a healthy diet and lifestyle which includes daily exercise and taking my Nucific Bio X4 religiously EVERY DAY! I truly believe taking BIO X4, eating right, and exercising have all been a huge part of my success in attaining my weight loss and overall wellness. To date as of this post, May 18, 2021, I weigh 150 lbs and no longer have any health issues and continue to take Nucific BIO X4, eat right, and exercise.

  2. Jim Greco


    BIO-X4 Evaluation
    I have been taking the BIO-X4 pill for a few weeks now and I am experiencing no stomach problems of bloating and gas and abdominal pain. I have started to lose some weight as well…I will continue these pills and hopefully, get even better results.
  3. Janeisha Bradley

    Bio X4, Ideal for digestion issues!
    Works well for digestion! I don’t go to the bathroom 20 times a day only like 2-3 times now! Glad I’ve found Bio X4 Nucific. I also get full faster now. I Don’t eat as much. I just take 2 before each meal and it really helps!
  4. Chris Winkler

    Life changing product!
    I’ve had stomach issues for years. This product has helped tremendously with all stomach issues plus I have more energy! Bio X4 is a great product for everyone who has stomach issues and needs to lose weight.
  5. Susan Davidson

    Helped curb the cravings! Weight loss coming slowly but there.
    I have been taking the Nucific Bio X4 pills for about 3 weeks. I have lost some weight slower than I was hoping. The biggest reason I take these probiotics is that it has taken my sugar cravings almost totally away. Once and a while I will have something sweet but don’t think about sweets 24/7. I also eat less food. Being a COVID 19 long-hauler has left me physically weak and am doing physical therapy and hope to be able to get more active again. Bio X4 is good for me.
  6. Robin R Morris

    Bio X4 does it really work?
    Does this product work if you have an ileostomy? If you are at your desired weight can it trim your waistline only?
  7. Erik B.

    Its a great product would recommend to everyone
    Since I have taken the Bio X4, I no longer get indigestion or any stomach pains like before. I also feel that it’s making my body digest food much better and keeping my weight down. Would recommend it to everyone.
Show 10 More Reviews

Leave a Reply

Your email address will not be published. Required fields are marked *

5000 characters remaining.

Explanation ?

Privacy Policy

Submitting this review means that you agree to our Review Guidelines, confirming that you are a verified customer who has purchased the product and may have used the merchandise or experienced the service, and providing only a real interaction and experience without ulterior motives or has an affiliate or business with the company in any way. By ticking this box and submitting this review, you also accept that submitting fake reviews is a violation of Consumer Health Digest’s Terms of Use and such conduct will not be tolerated.


How to Upload your Proof of Purchase:

Please follow the instructions listed below to upload your electronic proof of purchase.

  • To upload your physical paper receipt, simply take a picture of it with your camera or phone. You may also try taking a still picture of it with your computer’s webcam.
  • Once you have taken the picture, save the image as a JPG, TIF, or PDF file.
  • Please note that you cannot upload a file that is larger than 2MB.
  • Then all you have to do is click the Browse button and search for your receipt picture file. You can also drag and drop the file into the provided field.

If you are still not able to upload your proof of purchase, please contact us for further assistance (take a moment to look over the sample bill below).


**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

Helping the Cause

Make a Donation


Advertising Disclosure

The content that appears on this page is presented as an overview vs. comparative marketing. The provided information includes product information, overviews, buying guides, and product specifications. All trademarks, registered trademarks and service-marks mentioned on this site are the property of their respective owners. If something is factually inaccurate please contact us and let us know. By contributing your product facts helps to better serve our readers and the accuracy of the content.

The table below does not include all companies or all available products in the market but those that we promote as their affiliates. In full compliance with the FTC guidelines, please assume that any and all links on the table are affiliate links, and we may receive compensation if you click one of these and make a purchase. We are independently owned and the opinions expressed here are our own. All editorial content is written without prejudice or bias, regardless of sponsor or affiliate associations.