Nucific Bio-X4 Reviews: Does It Promote Weight Loss?

Nucific Bio-X4 is a weight loss product that helps ensure smoother and more comfortable digestion, helps reduce appetite and helps you live a healthier life.

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In This Review

Overview of Nucific Bio-X4

It is incredible to see how many individuals today are so committed to eating healthfully, especially those who are struggling with food intolerance and weight loss issues. Dr. Amy Lee has developed Bio-X4 Nucific, a probiotic-based supplement that aims to support weight loss through several mechanisms. This includes reducing appetite and unhealthy food cravings, as well as boosting the body’s fat-burning metabolism.

Nucific Bio-X4 is a four-in-one nutritional supplement designed to help one in weight loss management. Thus, it may assist you in achieving your desired goals and help you live a healthier life.

Features 4-In-1 Weight Management Probiotic
Form Capsules
Benefits Digestive Support, Energy, Immune Support, Weight Support
Ingredients Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus Plantarum, Bifidobacterium lactis, Bifidobacterium animalis, Amylase, Bromelain, Lipase, Green tea extract (50% EGCG), Slimaluma
Type Supplement

The product can help reduce appetite to consume fewer calories and thus minimize weight gain theoretically.

In this honest review, we’ll dive deep into the realities of this probiotic supplement. Does it work? Let’s find out here!

What is Nucific Bio-X4?

Nucific Bio-X4. Developed by Dr. Amy Lee, this probiotic-based supplement has a mission: to help you shed those extra pounds and feel your best but in a very unique way. It doesn’t just stop at one approach; it tackles weight management from four different angles.

Bio-X4 contains probiotics, digestive enzymes, appetite suppressants, and metabolism boosters, all working together to support your digestive health and weight management. Those probiotics, with 4 billion CFUs per capsule, help keep your gut bacteria in harmony. The digestive enzymes break down your food for better nutrient absorption, reducing bloating and discomfort. And those appetite suppressants? They help curb those pesky cravings. Plus, Bio-X4 gives your metabolism a little nudge in the right direction.

It’s a four-in-one package designed to help you on your path to a healthier lifestyle. So, if you’re aiming for your fitness goals and a happier, healthier you, maybe it’s time to give Nucific Bio-X4 a try.

How Does Nucific Bio-X4 Rate?

Overall Rating: 4.8

nucific bio-X4 imgNucific Bio-X4


Value for Cost

4.8/5Value for Cost

Return Policy

4.8/5Return Policy



Brand Highlights

  • Bio-X4 is manufactured by Nucific.
  • Nucific is founded by Amy Lee, an internal medicine professional in Riverside.
  • Health supplements produced by Nucific are BBB-accredited, and the safety of their products is assured.
  • Bio-X4 works in four unique ways to support gut health.
  • Nucific Bio-X4 is known for developing and releasing the most cutting-edge products.
  • They are committed to being a source of top-notch, original goods.

Key Ingredients

  • Green Tea Extract
  • Probiotic Blend
  • Caralluma Fimbriata
  • Digestive Enzyme Blend


  • It does not contain lactose, fillers, or gluten. The ingredients are 100 percent pure.
  • There’s a 90-day money-back guarantee. If the product does not give you the desired results, you can return it to the manufacturer and get a refund.
  • The packaging of this appetite suppressant supplement is environmentally friendly.
  • The supplement is clinically tested by third-party labs.
  • There is transparency about the company’s board members and their credentials.
  • The manufacturer offers free shipping.


  • You must maintain a proper diet and exercise for better results.
  • Results will vary for different customers.

Who is the Manufacturer of Nucific Bio-X4 Supplement?

  • Nucific Bio-X4

    Nucific Bio-X4

  • Dr. Amy Lee Nucific Bio-X4

    Dr. Amy Lee Nucific Bio-X4

  • Dr. Amy Lee Bio-X4

    Dr. Amy Lee Bio-X4

  • Nucific Probiotic

    Nucific Probiotic

This probiotic supplement is manufactured by Nucific, a California-based company led by Dr. Amy Lee, Nucific’s head of nutrition.

Dr. Amy Lee is board-certified by the American Board of Internal Medicine and a member of the National Board of Physician Nutrition Specialists and the American Board of Obesity Medicine. ‘We’ve simply accepted so much misinformation about weight loss as true,’ said Dr. Amy Lee, Nucific’s Head of Nutrition.

While Bio-X4 is a relatively new product, Nucific’s website is professional and comprehensive, emphasizing its mission to improve health and enhance well-being through products designed to address nutritional deficiencies.

Consistent with that intent for good health is concern over the environment’s health, so the product packaging is also earth-friendly.

We will conduct a thorough analysis of the ingredients found in Bio-X4, utilizing scientific studies to assess their potential to deliver the promised results or if the claims lack foundation.

Our team of experts will evaluate whether Bio-X4 is a worthwhile investment or a potential waste of money. Furthermore, we will present unbiased reviews from customers of Nucific Bio-X4, offering a comprehensive perspective on the product.

You can BUY it directly from the Official Website

How Does Nucific Bio-X4 Work?

BIO-X4 is designed to help you achieve and maintain great shape, while the weight loss supplement focuses on reducing your waistline. This product boasts a comprehensive blend of ingredients aimed at promoting fat loss and enhancing digestion.

One key ingredient is caffeine, found in green tea, which accelerates metabolism, inducing the body into the fat-burning state known as thermogenesis. This can lead to rapid weight loss while also providing additional energy to extend your workouts.

Additionally, BIO-X4 contains Caralluma Fimbriata, an ingredient known for its appetite-suppressing properties[1]. Research published in Medical Clinics in North America suggests that appetite suppression may play a significant role in weight loss, alongside metabolism[2].

The Nucific Bio-X4 formula is enriched with probiotics and digestive enzymes, which promote the growth of beneficial gut bacteria. This, in turn, aids digestion and helps prevent issues like gas and bloating. Studies, such as the one published in the Journal Nutrients, indicate that probiotics can contribute to rebuilding a healthy bacterial balance in the body, supporting overall well-being[3].

Feature Product & Coupon


#1 Weight Managing Probiotic

Health Benefits of Bio-X4

  • Manages Cravings*
  • Promotes Weight Management*
  • Supports Smoother Digestion*
  • Boosts Metabolism*
  • Reduce Appetite*

*Individual results can and will vary.

Bio-X4 Ingredients – Are they Safe & Effective?

A host of Nucific Bio-X4 ingredients are considered beneficial for ultimate digestive health and management. It contains a collection of vitamins, minerals, amino acids, and herbs that help to promote bowel regularity and support immune health.

Nucific Bio-X4 Supplement Facts

Bio-X4 Supplement Facts

It can be highly effective in supporting weight loss and includes the following key ingredients:

Green Tea Extract (100 mg)

Green tea extract, containing Epigallocatechin gallate (EGCG) as its primary component, is known for its ability to boost metabolism and facilitate fat loss, leading to rapid weight loss. A meta-analysis published in the International Journal of Obesity found that the catechins in green tea significantly contribute to weight reduction[4].

Notably, 50% of the green tea extract comprises EGCG.

Dr. Will Bulsiewicz states that, “catechins present in green tea extract are believed to boost metabolism and help burn fat, which could lead to potential weight loss.”

Probiotic Blend (4 Billion CFU)

The Probiotic Blend consists of various strains, including Lactobacillus Lacidophius, Larhamnosus, Lplantarum, Bifidobacterium lactis, and B animals, with a total of 4 billion CFU per capsule.

Probiotics can be beneficial for digestive health by improving nutrient absorption, enhancing the immune system, and reducing inflammation. He recommends probiotic blends containing a variety of bacterial strains, as they are particularly effective in promoting gut health. – Dr. Mark Hyman, A Functional Medicine Physician

Probiotics promote the growth of beneficial gut bacteria, support digestion, and reduce symptoms like bloating. They also bolster the immune system. A review in the ISNR Nutrition delves into the health benefits of probiotics[5].

Caralluma Fimbriata (166 mg)

Caralluma Fimbriata Extract acts as an appetite suppressant by convincing the brain that the stomach is full, leading to reduced body weight. It may effectively control hunger and cravings. A study in the Journal Perspectives in Clinical Research explores the link between Caralluma Fimbriata and weight loss[6].

Digestive Enzyme Blend (43 mg)

The Digestive Enzyme Blend includes Amylase from Aspergillus Oryzae, Bromelain, and Lipase from Rhizopus oryzae. Amylase is an enzyme that facilitates the conversion of starch into sugars, while Bromelain is naturally found in pineapple stems and can reduce inflammation caused by injury or surgery. Lipase aids in the hydrolysis of lipids. An article in the Bentham Open Access explores the use of digestive enzymes in certain digestive disorders[7].

Enzymes are the body’s workhorses, and a digestive enzyme blend can support their function. These blends may help individuals better digest food and absorb nutrients. – Dr. Josh Axe

You can BUY it directly from the Official Website

Benefits, & Safety of Nucific Bio-X4

Benefits of Bio-X4

Digestive Support: Bio-X4 contains probiotics, which are beneficial bacteria that can help promote a healthy gut microbiome and improve digestion.

Weight Management: Some users claim that Bio-X4 helps support weight loss by boosting metabolism and reducing appetite.

Enhanced Nutrient Absorption: The digestive enzymes in Bio-X4 may help improve the absorption of nutrients from the food you eat, supporting overall health and vitality.

Safety of Bio-X4

Natural Ingredients: Bio-X4 is formulated with natural ingredients like probiotics, digestive enzymes, and herbal extracts, which are generally considered safe for most people when taken as directed.

Potential Interactions: If you’re taking other medications or have underlying health conditions, consult with a healthcare professional before starting Bio-X4 to avoid potential interactions or adverse effects.

Potential Side Effects of Bio-X4

Digestive Discomfort: Some users may experience digestive side effects such as bloating, gas, or diarrhea, especially when first starting the supplement.

Allergic Reactions: Individuals allergic to any of the ingredients in Bio-X4 may experience allergic reactions, such as rash, itching, or swelling.

Potential Overdose: Taking more than the recommended dose of Bio-X4 can lead to digestive upset, nutrient imbalances, and other adverse effects.

Nucific Bio-X4 Before and After

According to the manufacturer, Bio-X4 by Nucific manages cravings, promotes weight management, supports smoother digestion, and boosts metabolism.

These claims are proven true from the Bio-X4 Before and After customer reviews. A reviewer shared her experience of how she was able to overcome her sugar cravings by taking a particular supplement.

According to her,

“Prior to using the supplement, I used to experience unhealthy cravings that caused digestive discomfort. However, after using the supplement for two months, I was able to shed 38 pounds and achieve a healthier body shape. Overall, the supplement proved to be effective in helping me control cravings and achieve my weight loss goals”.

Bio-X4 Before and After Pictures

Nucific Bio-X4 Before and After Pictures

Is Nucific Bio-X4 Safe?

Bio-X4 is a probiotic-based nutritional weight loss product. It seems safe and effective, based on the quality collection of organic ingredients. This product is safe for people who have gluten, allergen, and lactose sensitivities since it does not contain any of those ingredients.

Some individuals might experience mild adverse effects as their body has to adjust to probiotic foods being a regular part of their diet. Over time, these effects subside as their body gets comfortable with the introduced Probiotic.

No synthetic or chemical substances are included, and the product should not lead to side effects.

I Tried Nucific BioX4! And My Experience Was…

Nucific Bio-X4 Review

Nucific Bio-X4 Review. Photo by Andrea Tavalaro

I’ve been using Bio-X4 for a while, and soon I experienced that it completely transformed my digestion game. Previously, I would feel miserable after every meal.

After taking Bio X4, I can enjoy my meals and absorb all the nutrients properly without any issues. It has also helped me digest food with ease and maintain an optimal metabolism rate.

The ingredients are really simple but so effective. It contains digestive enzymes to break down food, probiotics for gut health, green tea extract for an antioxidant boost, and Caralluma fimbriata to curb cravings.

With Bio-X4, I finally have everything I need for smooth, comfortable digestion in one convenient supplement. I highly recommend giving Bio X4 a shot.~ Andrea Tavalaro

Following her experience with the supplement, the tester mentioned in her review that she would recommend this Bio X4. You can watch her review on our official YouTube channel, Consumer Health Digest.

Nucific Bio-X4 Review (Video Credit: ConsumerHealthDigest Review YouTube)

What Sets Bio-X4 from the Competition?

Bio-X4 is more than just a probiotic pill. It is a carefully crafted blend of various bacterial strains, digestive enzymes, and appetite suppressants. What sets Bio-X4 apart from the competition is its unique combination of ingredients, designed to promote digestive health, boost metabolism, and support weight loss.

The selection of probiotic strains in Bio-X4 was done with great care, aiming to strengthen the immune system and improve overall gut health.

One of the standout features of Bio-X4 is its digestive enzymes, which play a vital role in breaking down food more efficiently.

This not only enhances the absorption of nutrients but also reduces bloating and discomfort, leaving you feeling lighter and more energized. When it comes to weight loss efforts, Bio-X4 goes the extra mile with its appetite suppressants. These help curb cravings and minimize excessive eating, providing valuable support along your weight loss journey.

It’s worth noting that Bio-X4 is manufactured in a GMP-certified facility, ensuring that it adheres to strict guidelines for quality and safety. This commitment to high manufacturing standards adds an extra layer of assurance for those considering Bio-X4 as their chosen supplement.

SEE ALSOMulti-GI 5 and Bio Complete 3

Bio-X4 FAQ’s

Q: Who Should Take Bio-X4?

A: Bio-X4 can be beneficial for people who suffer from digestive issues and those who want to lose weight, even if they do not have a diagnosed digestive disorder. Bio-X4 is designed to optimize your overall digestive health — from the inside out.

It’s a fantastic choice for anyone who wants to enjoy smoother digestion, a slimmer waistline, smooth bowel movements, and higher energy levels.

Q: What Is the Dosage of Bio-X4?

A: Take 1 capsule of dietary supplement with every 3-time meal. Supplementing each meal with the digestive help assists to process your food, and obtaining the maximum amount of nutrients.

Q: How Many Capsules Are in One Bottle of Bio-X4?

A: A bottle contains 90 capsules, and you can buy it from the official website. The website offers different offers to help you save money on a purchase.

Q: What are the Side Effects of Bio-X4?

A: The manufacturer claims that Bio-X4 is free of any side effects. It is formed of pure elements. You can take them with your diet restrictions as they are gluten- and allergy-free. None of the Bio-X4 reviews mentioned having symptoms.

While the statement is generally true, it’s important to highlight that people who are thinking of taking the supplement need to be extra cautious and scrutinize the nutritional details mentioned on the label. This will ensure that none of the components of the supplement trigger an allergic reaction, especially if you have specific food allergies.

Furthermore, it’s critical to follow the recommended dosage mentioned on the product label carefully. Adhering to the recommended dosage and reading the label thoroughly is crucial to ensure safety and obtain the supplement’s full benefits.

Q: Does Bio-X4 Really Work?

A: Bio-X4 is 100% effective as it contains a potent blend of ingredients that support digestive health and substances that help with weight management and suppress cravings. A certified bariatric physician developed this product to help people achieve their weight loss goals, make dietary changes, and adopt healthy lifestyle habits over the long-term. Many consumers have left positive reviews sharing their incredible experiences with this product.

One reviewer says, “I bought the products mentioned in the title of this review and have been taking all three of them once a day, along with the Bio-X4 digestive enzyme twice a day. I’ve noticed that I no longer have the urge to snack during the day, feel full for longer, and don’t experience bloating. I’m even starting to see a reduction in the fat around my waistline – my jeans are fitting me more loosely. Overall, I’m really pleased with these products and would definitely recommend them”!

The sheer number of positive reviews is evidence enough for us that the Bio-X4 supplement really does work.


Q: What else does Bio-X4 do for you?

A: Some users of BIO-X4 have already reported seeing:

  • Reduced cravings for unhealthy junk food
  • Increased energy levels throughout the day
  • Boost Metabolism
  • An absence of gas, irregular visits to the bathroom, and bloating

In addition, this product does not contain gluten, lactose, or fillers, so those who are allergic to these ingredients will not react. The nutrients can accomplish this and suppress cravings for food.

The underlying rationale for the development was the recognition that people seldom get the absolute best nutrients daily from food, yet the body needs to operate at peak performance.

Q: How Long Does It Take to Show Results?

A: The duration of results depends on each individual. While most of the consumers after taking Nucific Bio-X4 have noticed results in the first 60 days, and some individuals have noticed the results in a few weeks. We would suggest combining the supplement with a healthy diet and exercise routine to achieve the best results in a short span of time.

Q: Can You Buy Bio-X4 in Stores?

A: No, you won’t find it in the stores. You can purchase it from its official website, with a 30-day supply of 90 capsules costing $99 (equating to $1.10 per capsule). Although there are more than 8,500 reviews of Nucific Bio-X4 on Amazon, it appears that the actual Bio-X4 product is not currently available for purchase on the platform. This is true not only for customers in the United States, but also for those in Australia, Canada, and any other part of the world. Despite the abundance of Bio-X4 Amazon reviews, the product itself cannot be bought through the website.

Q: Where to Buy Bio-X4?

A: To avoid any fraudulent activities, we recommend purchasing Bio-X4 directly from the Official Website, even though it may be available on other sites such as Amazon or Walmart. While these websites may offer the product, it’s best to stick with the official site for a secure and trustworthy purchase.

Q: How Much Does Bio-X4 Cost?

A: A bottle of Bio-X4 costs $99 which contains 90 capsules. If you purchase today, the company offers Bio-X4 for sale at a significant discount. Better still, you will save money when you buy three bottles and not a single bottle.

Q: Is Bio-X4 Worth the Money?

A: Yes. Bio-X4 probiotic pill may help ensure smoother, more comfortable digestion. Digestive enzymes aid digestion and increase nutrition absorption, allowing your body to stay fit! So far, there have been no complaints reported for Bio-X4, and the product has garnered numerous positive reviews. Additionally, the Better Business Bureau (BBB) has awarded Bio-X4 an A+ credit rating.

Q: Is Bio-X4 Legit or a Scam?

A: Nucific’s Bio-X4 is a completely genuine product that’s composed of natural ingredients. To steer clear of fraudulent activities, the company recommends buying the product from their official website and not from other online shopping sites like Amazon. Furthermore, numerous customers have given excellent feedback about the product on sites such as the official website, BBB, and Trustpilot. This clearly indicates that the product is not a scam but a trustworthy and legitimate one.

Q: Is Nucific Bio-X4 FDA Approved?

A: No, Bio-X4 isn’t FDA approved as FDA ( Food and Drug Administration) doesn’t approve dietary supplements. Although many dietary supplements are there in the market without FDA approvals and benefitting individuals. Nucific Bio-X4 customer reviews make this supplement a must-try.

Q: How can I get the most out of Nucific Bio-X4?

A: The best way to maximize the effects of Bio-X4, is by taking it consistently 3 times a day as well as combining it with a healthy diet and regular exercise. However, this supplement is fantastic on its own, but if you add some exercise and a healthy diet to it you will experience a dramatic effect.

Q: How to Return Nucific Bio-X4?

A: Nucific offers a 90-day Money Back guarantee for Bio-X4 at the official website. In case you don’t feel satisfied with the product, you can return it to Nucific within 90 days of purchasing and get a complete refund of the product price, except for the shipping fees.

Please get in touch with their Customer Service for assistance in processing your return:


Mon-Fri 5 AM-7 PM PST
Sat-Sun 6 AM-4:30 PM PST

Q: Is Nucific a Good Company?

A: Yes. Nucific is a well-known health supplement Brand. It’s a reliable brand with a solid reputation on the market because of its high-quality, well-researched products. It is one of the top weight loss supplements.

This company provides the best weight loss supplements with a 90-day money-back guarantee. Customers are satisfied, and praise the company for helping them achieve their desired body shape with natural ingredients. Moreover, the company has a high rating on websites like BBB, Trustpilot, and Highya.

Q: How Does Nucific Bio-X4 Rate?


Feature Rating Comments
Ingredients 10 Scientifically proven ingredients aid in the optimization of your digestive system and control unhealthy cravings, improve all-day energy, and provide slimming support.
Price 9.5 Average cost for the market for a high-level supplement.
Safety 9.5 Nucific is a well-known company that uses professionally sourced ingredients, gluten-free and allergen-free capsules, and offers a 90-day money-back guarantee.

Nucific Bio-X4 Customer Service Info

  • Address: 30700 Russell Ranch Rd Westlake Village, CA 91362
  • Email:
  • Phone: 888-679-5520
  • Hours: Mon – Fri 6 AM-5 PM PST, Sat-Sun 6 AM-4 PM PST
  • Contact form:

Nucific Bio-X4 Alternatives

There are a few products online with similar gut health and weight management claims as BIO-X4, but not many with the same combination of ingredients to produce this intended benefit.

The two most similar products in their health claims and ingredients are Morning Complete and Active-PK.

Product Morning Complete Active-PK
Price $49.00 $46.95
  • Improves digestion
  • Reputable manufacturer
  • Improves overall productivity
  • Reduces fat
  • Curbs food cravings
  • Burns visceral fat
  • Lowers cholesterol
Return Policy 90 days money-back guarantee 90 days money-back guarantee
Website Official Website Official Website

What Do the Nucific Bio-X4 Reviews Say?

Bio-X4 by Nucific has received mostly positive reviews from various websites, with many users praising its ability to reduce bloating, increase energy, and aid in weight loss. There are numerous positive reviews found on forum sites such as Quora and Reddit.

However, there have been some complaints about its effectiveness and cost from a small group of consumers. Unlike other weight loss supplements that make unrealistic claims, Bio-X4 by Nucific appears to deliver on its promises.

According to the official website, it has received a rating of 4.59 out of 5 from a total of 3,960 reviews. Here are some customer reviews of Nucific Bio-X4 from the official website:

It will help with severe constipation!

I was diagnosed with celiac disease about two months ago….eliminated gluten, dairy, and added sugar from my diet. I went from having a BM every 7-10 days to having a BM every 3-5 days. A few weeks ago, I started using this probiotic in hopes that it would help me increase my BMs. SUCCESS!!! Over the last four days, I’ve had a healthy BM each day!!!! For me, truly a miracle! This has not happened in over ten years! I highly recommend it!
~ Terri La Rue

Great product!

I was having stomach trouble. Everything I ate would cause me to have stomach pain and diarrhea. After two weeks of taking this, my system was back to normal and has been since.
~ Karen Drasheff

*Individual results may vary

We have also carefully researched the reviews on Highya and Trustpilot. At Trustpilot, the Nucific Bio-X4 has been provided 4.3 out of 5 from a total of 1,351 reviews.

One reviewer says, “I have noticed that when I take the Nighttime supplement along with Bio-X4, it really helps me lose weight effectively. On the other hand, when I don’t take BioX4, I can feel a difference in my appetite. It seems like the combination of both supplements is a powerful combination for weight loss”.

The Nucific Bio-X4 has also received a high rating of 4.3 out of 5 from a total of 1395 reviews on Highya. Based on this feedback, it seems that consumers love this product and recommend it as a dietary supplement for effective and healthy weight loss.

Bio-X4 Reviews – Conclusion

Nucific Bio-X4 is packed with rich organic ingredients that offer comprehensive digestive support, appetite suppression, and enhanced immune health. This supplement is designed to assist in weight loss by curbing cravings, reducing appetite, and boosting metabolism. Notably, it has quickly risen to become a top-rated product in the market, and its pricing is quite reasonable.

We wholeheartedly recommend this product, as the majority of Bio-X4 reviews are overwhelmingly positive. Many users reported significant weight loss, with some even providing Bio-X4 before and after pictures as proof of their success. Customers have also expressed satisfaction with the digestive benefits it provides. While there have been very few Bio-X4 complaints, there are virtually no negative reviews.

This high-quality product is composed of safe ingredients and is associated with no known side effects. It not only enhances digestion and aids in achieving a slimmer physique in record time but also supports overall health and immunity.

Where To Find It?

You can BUY Bio-X4 directly from the Official Website

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

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Customer Reviews for Nucific Bio-X4

Nucific Bio-X4 Reviews: Does It Promote Weight Loss?

Customer Reviews & Ratings

4.8 out of 5

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  1. Jeffrey C.

    i'm ordering more after a long break !
    When I ordered Bio-X4, I was thinking get 3 bottles and save some money! but, then saw if I bought 6 instead I would save even more! Ended up getting 9 bottles? oh well my bad. I’m 5′ 11″ and weighed 243 lbs at the time. I didn’t buy Bio-X4 to loose weight! I bought it in hopes that it would help with my energy level. which was pretty low. it did help! but, by the time I was into 6 months of taking Bio-X4 I only weighed 180 lbs. it didn’t feel right as I was so used to being over weight for so many years! friends and family were asking if I was sick! so I decided I should stop taking Bio-X4 before I get too skinny and gave the last 3 bottle away to a friend and a family member!

    I never heard what they thought about Bio-X4. I would say that you don’t start seeing any changes until you’ve been taking it for about 2 months and then it really snowballs! At least for me it did! now 6 or 7 years later I still only weigh 195 lbs.! But, now at 65 years of age I think I should get down to what they say would be my ideal weight of 176 lbs. so, I have ordered 3 bottles of something that I know works for me. I would think that Bio-X4 would do the same for anyone as long as you don’t eat a bunch of processed food! Just real food!

  2. David James

    product is good....
    I must say, this product is good…i have tried probiotics in the past but never experienced results like this before. after hearing positive reviews from friends and doing some research of my own, I decided to give Bio-X4 a try. It was a good decision…the money I spent on it was well worth it. I noticed a significant improvement in my digestion and energy levels. I’m definitely ordering another bottle!!!!
  3. Mellissa

    So grateful for this product!
    Bio-X4 is more than just a digestive aid; it’s been instrumental in my weight loss journey. The green tea extract provides a gentle boost to my metabolism, and the probiotics keep my gut health in check. I’ve seen positive changes in both my digestion and weight.
  4. Cynthia Celler

    Nucific Bio X4 really worked for me!
    I have been using this Bio X4 for nearly three months now, and I must say that I no longer experience the same intense cravings for sugar that I used to have, even though I enjoy adding sugar to my coffee.

    Snacking has always been a weakness for me, and I’ve struggled to resist it in the past. However, I believe this Nucific Bio X4 has significantly helped me reduce my desire for sugar and control my cravings for snacks.

    Additionally, I have started noticing positive changes in my abdominal area and love handles, as they appear to be slimming down. Now, I feel motivated to increase my level of physical activity and incorporate more exercise into my routine.

  5. Sheila Lamb

    Starting To See Results!:)
    I am almost finished with my first bottle of Bio X 4. I really needed something to help me lose some weight that I had gained several years ago. Until now, I have had no success. I know it isn’t much, but I have lost 5 lbs. since I have been taking this product. That is a small milestone to many, but a big encouragement to me. I can see that it’s working and I seem to have more energy than before also. Getting ready to buy my next bottle and see if I can keep it going in the right direction. Thanks, Bio X4! 🙂
  6. Selene

    No More Bloating!
    I suffer from terrible bloating, and this product really takes care of it and makes my whole digestive tract run much more smoothly. I also appreciate that I have dropped a few pounds since I did put on weight during the pandemic when I was stuck at home so much. It makes me less hungry, too, which is great.
  7. Ardele Steele

    Excellent Product
    I have been on the Bio X4 product for three months now with positive results…I have lost some pounds. Boost in energy and my cravings have changed.
  8. Ted Fox

    Couldn't be happier!
    After watching Dr. Amy’s video about her research, I decided to take the chance, as food (and especially sugary foods) had become my default source of comfort over the last 16 months of pandemic lockdown. Not to mention I simply couldn’t afford to keep buying new, larger pants.

    I started taking Bio-X4 exactly 4 weeks ago. I switched to a 70-80% plant-based diet, only eating chicken or beef once a week, and I was very persistent using the daily Diet Journals that came with my order. (They have made it so much easier to recognize patterns and bad choices.) Now, I am a 39-year survivor of HIV/AIDS and am eternally grateful for the medications that have kept me alive. However, those same meds have been wreaking havoc with my digestive system for more than a decade, leaving me seriously dependent on a daily intake of some type of Imodium.

    Within the first week, my ‘bathroom habits’ had made a complete 180, and I haven’t needed an anti-diarrheal since. That alone is reason to celebrate and stick with it. Even better, my sugar cravings and consumption have diminished by 80-90%. Of course, I have them still and occasionally give in, but for a life-long sugar junkie like me, that’s almost miraculous. I stepped on a scale two days ago for the first time since starting this program, and I was ecstatic to see I have lost 12 pounds over the past 28 days.

    I hardly know how to say thank you enough.
    Ted Fox

  9. Susanna Shipmon

    Bio X4 Reviews and Testimony
    Bio X4 had allowed me to lose weight in a safe and steady way that I haven’t been able to do any other way. It manages my cravings so I don’t overeat. I have regular bathroom habits which I didn’t always have. I feel light and I’m never bloated so my stomach looks thinner. I have plenty of energy and I haven’t felt sluggish since I started taking it.
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Bio-X4 Ques and Ans

  • Q: Are there any side effects for persons with Parkinson\'s disease?

    A: If you are on any medications or have any medical conditions, it is best to consult your doctor before adding the supplement in your diet.

  • Q: I am intermittent fasting eating only lunch every day. do I need to take 1 capsule at meal times or just one for the meal (lunch) that I eat?

    A: The manufacturers of Bio X4 suggest taking one capsule with each meal, based on three meals per day. However, they also state that you can take up to two capsules per meal. If you are only eating one meal a day (lunch) while intermittent fasting, you may consider taking one capsule with your meal. It is best to follow the recommended dosage and adjust it based on your specific eating pattern. Always consult a healthcare professional before making changes to your supplement routine.

  • Q: What about one who is in hospital for cancer. Down by 20 lbs. Can this product also help to regulate digestion to help gain proper weight? Wouldn\'t want him to lose any more but product sounds as tho it would benefit anyone.

    A: For an individual in the hospital for cancer and experiencing weight loss, it is crucial to prioritize their care under the guidance of healthcare professionals. It's important to consult with a healthcare provider before considering any supplement. They an suggest what is best for the patient with cancer.

  • Q: I am a type 2 diabetic who had a gastric bypass, which hasn't worked. Is this safe for me?

    A: Given your medical history, it is best to check with your doctor before starting any supplement. If he agrees, follow his dosage instructions or start with low doses and monitor your blood sugar closely for any unexpected fluctuations when first introducing Bio-X4.

  • Q: Does Bio-X4 work if you have an ileostomy?

    A: Bio-X4 pills are generally safe to consume. There have been many studies done on the effects of probiotics and the results vary.

    Some believe that more research is necessary. There is evidence that using probiotics at the same time as antibiotics, reduces the chance of diarrhea and infections. Further, it is shown the probiotics can be beneficial for diarrhea.

  • Q: Can people with Type 2 diabetes take BIO-X4?

    A: Not surprisingly, there are many types of probiotic supplements available, one of them is BIO-X4. Supplements may contain just one strain of probiotics, or they may have multiple strains.

    Common strains of probiotics include the Lactobacillus, Bifidobacteria, Saccharomyces boulardii, and Bacillus coagulans. It's a good idea to check with your doctor before taking a probiotic supplement. Some people should not take them, including people who have an overgrowth of yeast, small intestine bacterial overgrowth, or a compromised immune system.

  • Q: Can you or should you take these on an empty stomach? What if you only eat one meal a day and you only take it once a day in what extent will that help?

    A: Bio-X4 is best taken with your meals to increase digestion and enhance nutrient absorption. Taking more than three capsules a day may be possible. However, it must not exceed six.

  • Q: What if you forgot to take Bio-X4 a day?

    A: If you miss a Bio-X4 dosage for a whole day, just proceed as normal on the following day. It can allow the body to build up the best level of enzymes, nutrients, and beneficial bacteria.

  • Q: What quantity should I order?

    A: You can order 1, 3, or 6 bottles. If you really want to save money, order six bottles at once for a big discount.

  • Q: What is the telephone number for me to order and speak to someone. The number I have is wrong.

    A: You may contact them by calling on the number available on the official website. (888) 679-5520

  • Q: What does the date on the bottom of the container signify? I take 1 capsule per day and my original supply has lasted years…do these capsules lose potency over time?

    A: It's the date up until which the drug manufacturer can guarantee that the medicine is fully potent and safe to take based on scientifically sound product testing. It is usually expressed by month and year. The product can legally be used or dispensed until the last day of the stated month and year.

  • Q: Can You Take Bio-X4 While Pregnant?

    A: Although these are naturals ingredients and safe, according to the manufacturer, it is essential for pregnant women and nursing mothers to contact a doctor before using the product.

    Note: Always consult a doctor before starting any new supplements due to potential drug-nutrient interactions.

  • Q: Is this something one would need to take for the rest of his life?

    A: As observed above, a bottle has 90 capsules. Preferably, you should take one pill thrice daily, before meals, and with a glass of plain water. How long does Bio-X4 last? --- Bio-X4 does not last very long, especially when you consider the price. For almost $50 this product only lasts for 15 – 30 days.

  • Q: How Much Caffeine is in Bio-X4?

    A: Not a huge amount. There's some caffeine in green tea, and it's just enough to get your metabolism revved up and burning fat but not enough to leave you jittery.

  • Q: Is Bio-X4 effective for weight loss and safe for 12 to 13 years old kids

    A: Ages under 18 years old. Bio-X4 is made for adults who want to lose weight and have a compromised digestive system. Weight loss or probiotic supplements are not recommended for children.

  • Q: I ordered bio x and a small recipe book came with it but it was in another language. Can I get the book in English?

    A: That could have happened by chance. You must contact them, and they will assist you. here is the contact info: Mon – Fri 6 AM-5 PM PST Sat-Sun 6 AM-4 PM PST 888-679-5520

See more answered questions

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Nucific Bio-X4
90 Capsules
Green Tea, Probiotic Blend, Caralluma Fimbriata, and Digestive Enzyme Blend.

7 sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] The effect of an orally-dosed Caralluma Fimbriata extract on appetite control and body composition in overweight adults:
[2] Maintenance of lost weight and long-term management of obesity:
[3] Effect of Caralluma Fimbriata extract on appetite, food intake and anthropometry in adult Indian men and women:
[4] Effects of green tea on weight loss and weight maintenance. A meta-analysis:
[5] Health Benefits of Probiotics: A Review:
[6] ArtiFacts: The Resurrection of Cpl. William McVay After a Wrist Fracture:
[7] Digestive Enzyme Supplementation in Gastrointestinal Diseases:

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

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Note: Results may vary about any product effectiveness. The information contained in this website is provided for general informational purposes only. No medical claims are implied in this content, and the information herein is not intended be used for self-diagnosis or self-treatment of any condition.

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