Which Sleep Aids Really Work?

Most sleep aid supplements contain a blend of herbal and other natural ingredients that either has an anxiety-reducing or sleep-promoting effect.

Although not all sleep problems are a result of stress and anxiety, most people will probably benefit from natural sleep-promoting supplements as they target parts of the brain responsible for sleep.

The GABA receptors and neurotransmitters such as melatonin and serotonin are now recognized as playing a key role in human sleep[1].

Natural sleep supplements contain herbs and other ingredients that target these receptors and neurotransmitters to induce sleep naturally and with fewer side effects.

The Best Sleep Aids for 2022

What is the most effective natural sleep aid? To help you decide which sleep-promoting supplement should work for you, here is a list of the top 8 best sleep aids of 2022.

#1. Sleep Support Plus

If you’re looking for a solid night’s sleep with peaceful dreams, Sleep Support Plus could be the right product for you. This supplement for occasional sleeplessness is a mixture of herbal ingredients that lead to calmness, relief of stress, relaxation, and peaceful sleep. Some of these extracts also may lead to an increase in a positive mood, such as 5-HTP.

Sleep Support Plus supports an overall healthy cycle, helping you to regulate your hours so you sleep and wake at approximately the same time every day. This is healthier for your overall system and your well-being. In addition, you’ll be less likely to have a disrupted sleep punctured by waking up in the night.

Sleep Support Plus stands up well next to other best sleep supplements that are in the same class. It has a richer collection of ingredients than most similar products, and the price is very reasonable and affordable.

In addition, there are very few side effects that are associated with using this product, so you don’t have to worry about additional symptoms developing. You can just take your supplements at night and drift off into a peaceful sleep.

Read more about Sleep Support Plus here.

#2. New Mood

Manufactured by a company called Onnit Labs, Inc, Onnit New Mood is a 100% organic supplement which is designed to eliminate daily stressors morning, afternoon, and night. In addition, it can promote positive mood, and induce feelings of calm and relaxation.

Aubrey Marcus found this company in 2010, and it has its headquarters in Austen, Texas.
Their philosophy is to promote total human optimization. They are a highly reputable Fortune 500 company that has had a huge amount of success in the market.

This supplement includes high-quality ingredients like 5-HTP, chamomile, tryptophan, valerian, and magnesium. In addition to enhancing mood, the formula can help balance your blood pressure and support heart and nervous system health. Based on the substances included, it can also help promote a better quality of sleep.

Many of the Onnit New Mood reviews were very happy with this product and said it produced powerful results in terms of mood, relaxation, and decreasing feelings of anxiety. There were few negative reports or complaints about this product. The recommended dosage is 2 capsules at night, and also 2 during the day if you require. Don’t take more than 6 capsules in a 24-hour period.

Read more about New Mood here.

#3. Sleep Wave

Sleep wave is best sleeping pills made by a company known as Nutri-health. It is said to be made from natural herbs that are known to be effective sleep-promoting supplements. This can also be attributed to the promotion of deep relaxation. It can also work with hormones to restore the natural sleep cycle.

The supplement is said to be effective, especially for people with irregular sleep patterns. Another point to mention is that the active substances contained in the supplement can help restore the natural hours of sleep and reduce nervousness.

Sleep Wave supplement contains the following ingredients: Vitamin C, Vitamin B6, Valerian root extract, GABA, Lemon balm extract, Hops, Passionflower extract, Chamomile extract, L-theanine, and Melatonin.

All active ingredients in the product are claimed to have been tested and proven to make you calm before sleeping.

This product can be used by people whose natural sleep patterns have changed, those who get nervous and anxious before they fall asleep, and people in a bad mood that cause sleepless nights.
It is recommended that adults take two capsules for about 30 minutes or 1 hour before going to bed.

Read more about Sleep Wave here.

#4. VitalSleep

If you’re looking towards a night’s sleep with peaceful dreams, VitalSleep could be the right product for you. VitalSleep is a personalized and customized anti-snoring product and one of the many supplements in the market. VitalSleep can provide you with a night of peaceful and restful sleep. It is said that this product is BPA-free.

This product’s primary purpose is to prevent the user from snoring, which is known to cause a reduction in sleep quality.

VitalSleep is said to come in two sizes – one for the male and the other for the female. The female version is a little bit smaller than that of the male.

The manufacturer warns that VitalSleep may have some adverse effects such as moving tooth and bite changes, soreness, pain in the mouth and jaw, salivation, and clogging of the mouth.

The side effects of VitalSleep are said to be similar to most other snoring agents it competes with.

Read more about VitalSleep here.

#5. AirSnore Mouthpiece

AirSnore Mouthpiece

AirSnore Mouthpiece

Know More About AirSnore

The AirSnore Mouthpiece is quite a unique product. While the majority of the products that we are reviewing in this post come in the form of tablets that are taken a while before going to bed, the AirSnore Mouthpiece is rather a device that assists with improving sleep quality.

While the duration of sleep is often a concerning topic, individuals should not fail to recognize the importance of sleep quality as well. Poor sleep quality may still lead to adverse effects caused by sleep deficiency.

This device has been developed to address this particular issue, and can easily be combined with one of the tablets reviewed in this post for more powerful results.

The AirSnore Mouthpiece is, as the name suggests, a mouthpiece that is placed in the user’s mouth when they get into the bed. The device is very comfortable to wear and will not cause any strain on the user’s teeth or jaw.

The primary purpose of the device is to prevent the user from snoring, which is known to cause a reduction in sleep quality. It should be noted that additional drops from the same company, known as AirSnore Drops, can be ordered with the product to improve sleep quality further.

Read more about AirSnore Mouthpiece here.

#6. Melatrol

Melatrol is one of the more popular sleep aid supplements that can be found on the market today. The product is safe to use and has not been associated with any harmful side effects. The primary function of Melatrol is not to induce sleep in the user, but rather to prepare the user to make falling asleep significantly easier.

This is beneficial when compared to pharmaceutical drugs that induce sleep upon the user – such pills often come with side effects that may be unpleasant to the user. It should be noted that Melatrol is a trusted brand and has been available since 2002. The brand has become trusted amongst thousands of people as the perfect sleep aid that does not cause any serious side effects.

Melatrol is a melatonin sleep aid the primary ingredient found in it is Melatonin. This ingredient has been scientifically proven to assist with improving the user’s ability to fall asleep, as well as to improve overall sleep quality.

Additional ingredients also found in the Melatrol formula include Rhodiola Rosea Extracts, GABA, Passionflower, Valerian Root, and 5-Hydroxy Tryptophan.

Read more about Melatrol here.

#7. ZzzQuil

ZzzQuil is another relatively popular sleep supplement. The product is promoted as a natural treatment option for individuals who are suffering from insomnia.

According to the manufacturer of this supplement, the formula has been developed in such a way to help reduce the time it takes the user to fall asleep after they get into bed, to improve their mind calm down, to reduce anxiety, and to help enhance the quality of their sleep.

One particular benefit that a lot of users like is the fact that ZzzQuil is available in both capsule and liquid form. The capsules are referred to as LiquiCaps. Different sizes of each option are available for the convenience of the user, as well as to suit their budget.

The ingredients found in ZzzQuil are non-addictive, which means users can use this product without being at risk of becoming addicted to the supplement.

The primary active ingredient found in ZzzQuil is Diphenhydramine HCL. This ingredient is effective in reducing anxiety and reducing alertness; thus making sleeping much easier for the user. It should be noted that the liquid form of ZzzQuil contains alcohol, which may be unpleasant for some potential users.

Read more about ZzzQuil here.

#8. Somnapure

Somnapure is a trusted sleep aid that has been developed by a reputable company, known as Peak Life. The manufacturer of the product is known to produce effective natural supplements to provide improvements in a variety of health conditions and other common ailments that individuals often suffer from.

Somnapure has an official website that represents the product. The website can be utilized to find more information about the product, as well as to gain access to customer support.

The product claims to improve sleep quality and duration, and to assist with improving the particular symptoms that people often suffer from when they are unable to obtain enough sleep during the night – such symptoms include cognitive impairment, irritability, memory loss, and more.

The ingredients found in these strongest sleep aid pills include Chamomile Extract, Passionflower Extract, Hops, Valerian Root, L-Theanine, Lemon Balm, and Melatonin. This is quite a powerful combination, and the majority of the ingredients found in these best sleep aid products have scientific research to back up the claims made about the particular substances.

At the moment, customers can opt for a risk-free trial offer from Somnapure to test the product before they invest a full one-month supply.

Read more about Somnapure here.

Why Do We Need Sleep?

Sleep is something that we need to stay awake the following day. We have all experienced that sensation of tiredness after a late night of partying or working until 3 AM.

Tiredness and cognitive impairment, however, are not the only side-effects of poor sleep.

According to a review published in Current Neuropharmacology[2], these herbs were found to be highly effective in promoting sleep according to most studies.

The National Sleep Foundation[3] explains that sleep is essential for the consolidation of memories and to properly prepare the brain for the information that will be obtained and processed the next day.

Additionally, it is also important to realize that sleep does benefit not only the mind but also the rest of the body.

Poor sleep habits can contribute to heart disease, obesity and many other adverse health effects. For this reason, acting upon sleeping problems such as insomnia should be important in order to benefit from the benefits that sleep has to offer, as well as to prevent the increased risk of chronic disease and health ailments caused by sleep deficiency.

What you must know about Ingredients in Sleeping Pills?

Most sleep-promoting supplements contain a blend of different ingredients, such as:

  • 1. Melatonin
  • 2. Lavender
  • 3. Chamomile
  • 4. Lemon balm
  • 5. L-tyrosine
  • 6. L-theanine, and others

These were found in various studies[4] to help with sleep problems that are either caused by stress, anxiety, psychiatric disorders, or medical conditions.

The products may also contain binding ingredients and preservatives that you need to look out for in case you have specific allergies. But all in all, most of the ingredients in natural products are completely safe and don’t cause any side effects.

Sleep Problems Info

All about Sleep and its Problems

Do Sleep Aid Supplements Really Help you to Fall asleep?

The answer to this is: it depends. If, for instance, you suffer from sleep apnea, then these products may not work for you as they don’t address breathing disorders but rather changes in normal brain functioning.

Furthermore, some ingredients such as melatonin may not start showing any effects until a couple of weeks of use while others such as a lavender kick in with first use. And also, if you have chronic insomnia, these supplements may not provide much relief so you may need to take prescription medicine before switching to natural sleep remedies.

How to Choose the Best Sleep Aid Supplements?

What is the best over-the-counter sleep aid? When choosing top rated sleep aid supplement, make sure the company whose product you are purchasing is reliable.

You can look for customer testimonials, the company’s overall market presence, clinical trials, and certificates to see if the company is reliable.

Other things to look out for are, of course, the ingredients. Make sure that clinical trials support the ingredients in your product.

Luckily, most popular supplements do contain true and tried ingredients so you won’t have to worry about their safety and efficiency.

Best Sleep Aids

Get solution for your all Sleep Problems

Natural doesn’t mean safe – While some remedies, such as a lemon balm or chamomile tea are generally harmless, others can have more serious side effects and interfere with or reduce the effectiveness of prescribed medications. Valerian, for example, can interfere with antihistamines and statins. Do your research before trying a new herbal remedy and talk with your doctor or pharmacist if you have any pre-existing conditions or prescriptions that you take.

How to use sleeping pills safely

According to the Medical News Today, always follow a doctor’s instructions for using hypnotic sleeping medication.

The American Academy of Sleep Medicine advises the following for people taking sleeping pills:

  • Never take a pill without a doctor’s approval.
  • Start with the lowest recommended dose.
  • Never mix sleeping pills with alcohol or other sedative drugs.
  • Take the first dose when you have planned no activities for the next morning.
  • Never drive a car or operate machinery after taking a sleeping pill.
  • Carefully read the package insert that comes with your medication.
  • Contact a doctor right away if any complications occur.

CAUTION: People taking prescription sleeping pills should contact their healthcare team if they experience:

  • extreme joy
  • anxiety
  • problems focusing
  • drowsiness in the morning
  • dependency on medication for sleep

Older adults should also speak to their doctors if they experience any problems with concentration, thinking, or memory.

What are the Side effects of over-the-counter Sleep Aids?

Even when used on a short-term basis, sleep aids, like most drugs, may cause side effects that make them unsafe for some people.

Over-the-counter sleep aids do have fewer side effects than prescription sleep aids, but they are still important to be aware of. They include:

  • Nausea and Headaches
  • Forgetfulness and Feelings of dizziness
  • Moderate or severe daytime drowsiness
  • Blurred vision or dry eyes
  • Constipation or urinary retention
  • Dry mouth, nose or throat


Sleep disruption can happen for a wide range of reasons, with the most common being heightened stress and anxiety.

For those who believe they have anxiety-related insomnia, turning to natural and herbal supplements may be the best option.

However, some people experiencing chronic and severe insomnia may need to take prescription medication before their sleep disorder wreaks havoc on their health and life.

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Robert, DO, FCCP

Dr. Robert S. Rosenberg DO, FCCP, is the medical director of the Sleep Disorders Center of Prescott Valley, Arizona, and sleep medicine

[1] All about Seeze https://www.tuck.com/sleep/can-you-sneeze-in-your-sleep/
[2] Shi Y, Dong JW, Zhao JH, Tang LN, Zhang JJ. Herbal Insomnia Medications that Target GABAergic Systems: A Review of the Psychopharmacological Evidence. Curr Neuropharmacol. 2014;12(3):289-302. doi:10.2174/1570159X11666131227001243 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023459/
[3] Memory and Sleep https://www.sleepfoundation.org/excessive-sleepiness/performance/improve-your-memory-good-nights-sleep
[4] Gooneratne NS. Complementary and alternative medicine for sleep disturbances in older adults. Clin Geriatr Med. 2008;24(1):121-viii. doi:10.1016/j.cger.2007.08.002 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276624/
[5] Why Do We Need Sleep? https://www.sleepfoundation.org/articles/why-do-we-need-sleep

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."