Progesterall Cream Reviews – Does It Live Up to Its Claim?

Progesterall is a menopause-relieving supplement that uses an advanced liposome-mediated delivery system that ensures maximum absorption of ingredients.

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In This Review

What is Progesterall?

Progesterall is a natural balancing cream that melts readily into the skin without leaving a greasy residue. It contains natural ingredients that are safe for use.

The product can be ordered online even by using a phone or even the mail. There is a contact number on the official website that enables customers to determine the total cost of the order including shipping.

How Does It Rate?

Overall Rating: 3.3

Value for Cost

3.2/5Value for Cost
Return Policy

3.4/5Return Policy


Brand Highlights

  • Balances mood and healthy energy levels.
  • Improved sleep, heart health, hair, skin, and nails.
  • 30 Day refund-policy


WellMe MenoRescue

*All individuals are unique. Your results can and will vary.

Key Ingredients

  • Capryllic/Capric Triglyceride
  • Simugel
  • USP Natural Progesterone
  • Lecithin
  • Grapefruit Seed Extract
  • Sodium Hydroxymethylglycinate
  • Potassium Sorbate
  • Tocopheryl Acetate


  • It may be effective for balancing hormones.
  • It is easy to apply.
  • It is used to control premenopausal & menopausal symptoms.
  • It deals with mood swings, hot flashes, tender breasts, etc.


  • The cream is only available online.
  • Its result may vary from person to person.

How Does Progesterall Cream Work?

Progesterall cream uses an advanced liposome-mediated delivery system[1] which ensures maximum absorption of ingredients. The ingredients are very effective in relieving premenstrual syndrome, and premenopausal, and menopausal symptoms.

The symptoms include; mood swings, vaginal dryness, tender breasts, migraines, osteoporosis, low sex drive, hot flashes, infertility, night sweats, and abnormal weight gain. A balance in a concentration of estrogen and progesterone clears all these symptoms[2]; the ingredients are safe and effective.

Progesterall Ingredients – Are they Safe & Effective?

Capryllic/Capric Triglyceride

– A mixture of coconut oil and glycerin that works as an emollient, dispersing agent, and solvent that helps to smooth skin and works as an antioxidant[3].


– A thickening agent found in cosmetics, sun care, and hair care.

USP Natural Progesterone

– A natural hormone that is used to re-create hormones produced when ovulating, it is often combined with estrogen to treat symptoms of menopause[4].


– A fat that is applied to the skin as a moisturizer to provide relief from blood pressure and enhances energy levels[5].

Grapefruit Seed Extract

– A citrus extract made from the seeds and pulp of the grapefruit that is said to be particularly beneficial for perimenopause symptoms, it is also effective in improving the physical and psychological symptoms of menopause while increasing muscle mass and reducing blood pressure[6].

Sodium Hydroxymethylglycinate

– An antimicrobial preservative that works as a formaldehyde release.

Potassium Sorbate

– A chemical additive used as a preservative in personal care products, it is generally odorless and tasteless salt.

Tocopheryl Acetate

– A form of Vitamin E containing protective antioxidants that may reduce free radical damage, it is in the form of soluble anti-oxidant[7].


Over 30 Hormone Solution

*All individuals are unique. Your results can and will vary.

Progesterall Questions and Answers

Q: How to Take Progesterall?

A: About an eighth(1/8) to a quarter(1/4) teaspoon of Progesterall cream is gently massaged per day into body parts of thinner skin such as the chest, face, inner arms, thighs, palms of the hands and soles of the feet which are not callused.

For more effective results, the larger portion of this dose should be applied at bedtime while the small portion of the dose applied in the morning.

At times, for convenience, the whole dose can be applied at once. The areas of the application should be rotated to avoid saturation.

There is a dot at the back of the cream tube that can be used for measuring the quantity of the cream to be used for an application.

For premenopausal women with an approximate 26 – 30-day menstrual cycle, the first month of cream use should be on the 10th to 12th day of the menstrual cycle. This should go on until 1 or 2 days before the expected period.

If the periods start before the last expected day, then the user should stop using the cream and start counting again from the 10th, 11th, or 12th day. This may take between 2 or 3 use cycles to achieve desired results.

For menopausal women, 1/8 – ¼ teaspoon of the cream is applied for 24 – 26 days in line with the calendar month. In fact, it is even easier to start applying the cream on the 1st day of the month until the 24th to 26th day and stop until the next month, 5 to 6 days.

Some break for the first 5 to 6 days of the month after which they apply the cream for the rest of the month.

Q: How Much Does Progesterall Cost?

A: A tube of this cream costs $21.95. Large discounts are offered for bulk purchases of Progesterall cream. For example, 12 tubes of this cream only cost $215.40. Six tubes of Progesterall cost $119.70.

Q: What are the Ingredients used in Progesterall?

A: Potassium Sorbate, Grapefruit Seed Extract, and Sepigel.

Q: What are the Precautions When Using This Supplement?

A: The customers should seek consultation from a registered physician for a prescription before using the cream. The menopause supplement should not be used orally. Progesterall cream should not be used by children.

Q: Does It Interact with Other Medications?

A: It does not react with other medications like other health products. It can be used together with other medications without causing adverse complications that are hard to manage.

Customers Reviews

Somewhat helpful.

Somewhat helpful. Definitely not as good as other progesterone creams I’ve used. I thought the size was a good value but not so much as it is to be applied at least twice a day.
~ Margaret O.


WellMe MenoRescue

*All individuals are unique. Your results can and will vary.

Progesterall Review – Final Verdict

Progesterall cream is the cheapest, natural menopause supplement that is recommended for use as a balancing cream.

It is derived from natural ingredients that are safe and free from side effects. It is backed by research and consumer reports that have been posted on most internet websites.

For more effective results, the cream should be applied after a warm shower. Progesterall cream should not be applied on top of makeup. The cream should be left to soak completely before the application of makeup.

Fortunately, natural therapies for menopausal symptoms such as weight gain, hot flashes, night sweats, decreased libido, and mood swings are available. Since many women experience weight gain during menopause, many natural menopause supplements contain herbs and botanicals that support a healthy metabolism. Menopause supplements should be evaluated on proven ingredients, ability to reduce hot flashes and night sweats, ability to provide hormonal balance and boost libido and its overall value.

Below you'll find some of the most effective menopause supplements on the market today, in our opinion.

Our Top Menopause Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned menopause supplements and vitamins based on the available research:

WellMe MenoRescue | Doctor Formulated
Relieves Symptoms of Menopause*Gold Star Evidence
Supports Hormonal Balance*Gold Star Evidence
Provides All-Day Energy*Strong Evidence
Balance Mood Swings*Gold Star Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Over 30 Hormone Solution | Revolutionary Hormonal Balance
Addresses Hormonal Changes*Gold Star Evidence
Boosts Metabolism*Gold Star Evidence
Enhances Sleep Quality*Strong Evidence
Improves Energy Levels and Vitality*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Amberen | Best Multi-Symptom Menopause Relief Supplement
Reduces Hot Flashes*Gold Star Evidence
Helps Restore Hormonal Balance*Gold Star Evidence
Better Sleep*Strong Evidence
Mood Improvement*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Bonafide Relizen | Menopause Relief Supplements
Cooling Relief From Hot Flashes*Gold Star Evidence
Powerful Hormone-free Relief*Gold Star Evidence
Helping Better Night's Sleep*Strong Evidence
Eliminate The Occurrence Of Night Sweats*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Progesterall Cream

Progesterall Cream Reviews – Does It Live Up to Its Claim?

Customer Reviews & Ratings

3.0 out of 5

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  1. Deborah George

    Made me feel too drowsy during the day.
    Having spent hundreds of dollars to try and ‘fix menopause’ and ‘menopausal insomnia’ I spent more and tried this on the recommendation of somebody on a forum.
    While it did slightly improve my sleep, it still didn’t get me through the entire night (I woke up early, stunting my sleep hours).
    The worst part about using the cream was how dopey and drowsy I felt the next day. I just couldn’t function normally, so I stopped the cream cold turkey which made me feel weird for a few days. I threw away 85% of the product. More money down the drain trying to fix menopause and insomnia

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Progesterall Ques and Ans

  • Q: How much progesterone USP is in your cream? Do you know or is it some extract such as YAM or SOY? People seem to think that you are selling a pure progesterone product which seems misleading. USP grade would be 100% pure which is not sold over the counter?

    A: According to the manufacturer's website, each full pump of ProgesterAll cream dispenses about 1 gram of cream, which contains 20 mg (milligrams) of natural, bio-identical USP progesterone. The progesterone used in the cream is of USP grade, which means it meets the standards set by the United States Pharmacopeia and is considered to be of high purity. It is important to note that this cream provides natural progesterone and not an extract from sources like yam or soy. The claim of selling a pure progesterone product may be misleading, as over-the-counter products typically do not contain 100% pure USP-grade progesterone.

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Progesterall Cream
John Lee MD Solutions
2.0 Fl Oz
Capryllic/Capric Triglyceride, Simugel, USP Natural Progesterone, Lecithin, Grapefruit Seed Extract, Sodium Hydroxymethylglycinate, Potassium Sorbate and Tocopheryl Acetate.

8 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Akbarzadeh, A., Rezaei-Sadabady, R., Davaran, S., Joo, S., Zarghami, N., & Hanifehpour, Y. et al. (2013). Liposome: classification, preparation, and applications. Nanoscale Research Letters, 8(1). doi: 10.1186/1556-276x-8-102
[2] Wharton, W., E. Gleason, C., Sandra, O., M. Carlsson, C., & Asthana, S. (2012). Neurobiological Underpinnings of the Estrogen - Mood Relationship. Current Psychiatry Reviews, 8(3), 247-256. doi: 10.2174/157340012800792957
[3] Zhao, W., Varghese, M., Vempati, P., Dzhun, A., Cheng, A., & Wang, J. et al. (2012). Caprylic Triglyceride as a Novel Therapeutic Approach to Effectively Improve the Performance and Attenuate the Symptoms Due to the Motor Neuron Loss in ALS Disease. Plos ONE, 7(11), e49191. doi: 10.1371/journal.pone.0049191
[4] Fugh-Berman, A., & Bythrow, J. (2007). Bioidentical Hormones for Menopausal Hormone Therapy: Variation on a Theme. Journal Of General Internal Medicine, 22(7), 1030-1034. doi: 10.1007/s11606-007-0141-4
[5] Hirose, A., Terauchi, M., Osaka, Y., Akiyoshi, M., Kato, K., & Miyasaka, N. (2018). Effect of soy lecithin on fatigue and menopausal symptoms in middle-aged women: a randomized, double-blind, placebo-controlled study. Nutrition Journal, 17(1). doi: 10.1186/s12937-018-0314-5
[6] Terauchi M, Horiguchi N, Kajiyama A, Akiyoshi M, Owa Y, Kato K, Kubota T. Effects of grape seed proanthocyanidin extract on menopausal symptoms, body composition, and cardiovascular parameters in middle-aged women: a randomized, double-blind, placebo-controlled pilot study. Menopause. 2014 Sep;21(9):990-6. doi: 10.1097/GME.0000000000000200. PMID: 24518152.
[7] Wander RC, Du SH, Ketchum SO, Rowe KE. Effects of interaction of RRR-alpha-tocopheryl acetate and fish oil on low-density-lipoprotein oxidation in postmenopausal women with and without hormone-replacement therapy. Am J Clin Nutr. 1996 Feb;63(2):184-93. doi: 10.1093/ajcn/63.2.184. PMID: 8561059.

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

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