Menopause is not a medical condition. It is nothing more than the normal transition wherein the reproductive years of a woman end. The biggest problem with menopause is the symptoms that can wreak havoc on the life of the menopausal woman.

The symptoms can even last a couple of years starting a few years before the actual menopausal stage. There are several treatment options available for the symptoms of menopause.

Currently, menopause relief products are the most popular because of the serious negative effects on the health associated with hormone replacement therapy.

Estro500 Overview


Estro500 is a topical cream that is formulated to provide relief for the symptoms of menopause. It is made by Natural Living Company which is based in Las Vegas, NV and is only sold in select retail stores.

However, it can be ordered online from anywhere in the world. The product claims to alleviate menopausal symptoms including hot flashes, mood swings, anxiety and weight gain.

It comes in an airless pump dispenser. The product claims to contain estriol and estradiol which are bio-identical to human estrogen. It contains 80% estriol and 20% estradiol. It is being sold as a cosmetic product so a prescription is not necessary.

Estro500 Ingredients

The ingredients of Estro500 are estadiol, estriol, grapefruit seed extract, tocopheryl acetate, potassium sorbate, aloe barbadensis leaf juice, SD alcohol, phenoxyethanol, laureth-7, C13-14 isoparaffin, deionized water, polyacrylamide and caprylic/capric triglyceride.

The problem is that there is no explanation of each ingredient and how they work on the product’s website.

Clinical Studies

There is no clinical study conducted on Estro500 proving its safety or effectiveness. This is not a good sign since the product may cause adverse effects on the user.

There is no indication that the estriol or estradiol used in the product are authentic and can really help with menopause symptoms. In fact, the FDA has yet to approve medications for menopause symptoms that contain estriol.


*All individuals are unique. Your results can and will vary.

In recent years the FDA has sent warning letters to companies that include estriol in their product’s formulation.

Does Estro500 Really Work?

It is uncertain whether Estro500 really works or not. This is because there is no clinical study proving its effectiveness.

Also, most of the reviews on the product are negative saying it doesn’t really help provide considerable relief to menopause symptoms. There is some feedback from customers saying it has minimal effects.

Does Estro500 Irritate the Skin?

It is stated on the product’s website that Estro500 may cause mild irritation to the skin. It is also possible that a hypersensitive reaction will occur if the user is allergic to any of the ingredients.

There is some customer feedback saying it has caused simple skin irritation but nothing really serious.

Is Estro500 Effective?

According to heaps of feedback, Estro500 may provide some relief of the symptoms of menopause but the effects are not as significant compared to menopause supplements and other treatments.

There is a money-back guarantee stated on the website but the refund is only offered on unopened bottles.

Final Verdict

Estro500 is okay as a menopause relief product since it may offer some relief of menopausal symptoms.

Comprehensive research will help you find the right menopause relief products that offer optimal respite from the dreaded symptoms of menopause.

Check out some other products available on the market like Estro-Aid, Estro-Care, Estro Flavone, and Estro-Logic.


*All individuals are unique. Your results can and will vary.

Fortunately, natural therapies for menopausal symptoms such as weight gain, hot flashes, night sweats, decreased libido, and mood swings are available. Since many women experience weight gain during menopause, many natural menopause supplements contain herbs and botanicals that support a healthy metabolism. Menopause supplements should be evaluated on proven ingredients, ability to reduce hot flashes and night sweats, ability to provide hormonal balance and boost libido and its overall value.

Below you’ll find some of the most effective menopause supplements on the market today, in our opinion.

Our Top Menopause Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned menopause supplements and vitamins based on the available research:

Amberen | Best Multi-Symptom Menopause Relief Supplement
Reduces Hot Flashes*Gold Star Evidence
Helps Restore Hormonal Balance*Gold Star Evidence
Better Sleep*Strong Evidence
Mood Improvement*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Estroven Complete Multi-Symptom Menopause Relief
Reduces Menopause Symptoms*Gold Star Evidence
Reduces Night Sweats*Gold Star Evidence
Improve Energy*Strong Evidence
Support Mood Swings*Moderate Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Metagenics Estrovera | Plant-Derived Menopausal Hot Flash Relief
Assists With Hot Flashes*Gold Star Evidence
Improve Mood Swings*Moderate Evidence
Ease Menopause Symptoms*Strong Evidence
Reduces Night Sweats*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Estro500

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Estro500 Reviews

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

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