HIV/AIDS is one of the dreaded diseases in today’s world. It is classified as a range of conditions that affect the human immune system. The immune system of your body protects it from a range of infections and illnesses. Once HIV invades the system, your body simply cannot protect it from infections and foreign invasions. Under normal conditions, if a foreign particle or microbe enters your body, your immune system can flush it out. However, the HIV gets into your body, your system cannot get it out- Since the terms HIV and AIDS refer to the same disease, they are often confused. While HIV is the virus causing the infection, AIDS or acquired immunodeficiency syndrome is the final stage of the infection. Every person infected with HIV does not necessarily have to progress to this stage. When you suffer from AIDS, you would have a very poor immune system. In this article, you will learn about this disease and how it affects you and your life.
Signs and Symptoms of HIV
An HIV infection has three main stages. The signs and symptoms vary according to the stage of infection as:
- Acute Infection
- Clinical Latency
An acute infection is the first stage, and it is the body’s natural response to any foreign invasion. It sets in within 2-4 weeks after the initial HIV infection. People suffer from flu-like symptoms such as
Among these, the most common symptom is fever. Some people call it as the ‘worst flu ever’. The symptoms can last for a period ranging from a few days to a few weeks. Suffering from any of the above symptoms does not mean you are suffering from HIV/ AIDS. It is also not necessary that every HIV+ person should undergo these symptoms. Many infected people do not suffer from any of the symptoms for more than ten years.
After the ‘worst flu’ symptom, the next stage is called ‘clinical latency’. As the name suggests, it is a period when the virus starts living in a human body. This stage can last anywhere between three to twenty years. On an average, however, the window period is eight years. People commonly do not experience any symptoms at this stage. Symptoms, if any, are very mild and almost go unnoticed. Towards the end of latency, people start experiencing symptoms like
- Weight loss
- Muscle pain
- Gastrointestinal problems
- Persistent generalized lymphadenopathy: About 70% of the patients suffer from an unexplained enlargement of lymph nodes. Every lymph node except those in the groin enlarges for 3-6 months. This is called persistent generalized lymphadenopathy.
The virus reproduces at a very slow pace during this period. This is because it is getting used to the new host and is adapting to the body. During this period, taking anti-retroviral therapy helps you keep a check on the viral growth. Thus, you can live for several decades.
This is the final stage of the disease. The onset of symptoms like weight loss, fever towards the end of the latency period signals the transition to AIDS. A person suffering from AIDS experience the following symptoms:
- Rapid loss of weight
- Prolonged swelling of the lymph nodes
- Unexplained tiredness
- Profuse night sweat
- Recurring fever
- Diarrhoea lasting for more than a week
- Blotches on the skin particularly inside the nose, mouth, eyelids or just beneath the skin
- Memory loss
- Neurologic disorders
In addition to these there are opportunistic infections caused by fungi, bacteria, viruses and such other parasites. These infections would affect nearly all the organs and organ systems in the body.
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Causes and Risk Factors of HIV
Unlike many diseases HIV does not spread through air, water, insects, toilet seats, saliva, drinking fountains, casual contacts, etc. Certain body fluids transmit HIV such as:
- Pre-seminal fluid
- Vaginal fluids
- Breast milk
- Rectal fluid
When these fluids come in contact with the mucous membrane of the body or get injected directly into the bloodstream of the body, there is a risk of transmission.
HIV is Mainly Spread By
- Sharing syringes, needles and other work equipment with an HIV+ person. These equipment must be be sterilized properly using the standard practices before sharing.
- Having unprotected sex with an HIV+ partner.
- Having multiple partners or infected with sexually transmitted diseases increase the risk of having HIV infections.
Less commonly, HIV is spread in the following ways
- From an infected mother to child during the time of pregnancy, childbirth or breastfeeding.
- Being injected with an HIV-contaminated needle or a similar sharp object. This is a particular risk factor among healthcare workers.
- During blood transfusion if the blood is HIV+ then the person receiving the transfusion would get infected. The case is extremely rare since the blood is usually tested before transmission. However, if the donor is undergoing ‘clinical latency’ period and if he or she has not suffered from any acute infections in the initial stages, then the HIV infection may go undetected and the recipient is likely to get infected. The chances are extremely rare.
Tests and Diagnosis of HIV
The diagnosis is done using laboratory testing and screening. While testing is done for all people ranging from 15-65 years, there are additional tests done for the high-risk groups including those diagnosed with sexually transmitted diseases. People infected with HIV develop specific antibodies called seroconvert within 3-12 weeks of infection. Primary infection is diagnosed by measuring HIV-RNA. A positive result is confirmed using PCR techniques. However, antibody tests in babies younger than 18 months are not always accurate owing to the presence of maternal antibodies.
Treatments and Medications of HIV
During the initial times, no antibiotic or therapy was readily available. Hence, an HIV+ person was certain to face death in a short period. However, thanks to the progress of science, there are medicines available. Though there is no medicine available as yet to gain complete cure from HIV/AIDS, there is therapy available for delaying the latency period and the onset of AIDS. This anti-retroviral therapy delays the growth of the virus within the human body. Thus, the transition of the disease from clinical latency to AIDS is delayed. In case of pregnant women and lactating mothers, there are medicines available to avoid the transmission of the disease from mother to child.
Precaution and Self-Care
Using a condom during sexual contact with an infected partner would reduce the risk of AIDS to a great extent. It is always wise and advisable to avoid multiple partners and maintain loyalty. In case of vertical transmissions from mother to child, in addition to medications during pregnancy, babies are bottle-fed. Breastfeeding is avoided so as to reduce the risk of transmission.
There are many misconceptions about AIDS such as they spread through casual contact, sharing the same seat, etc. An open discussion about the disease must be encouraged in schools and awareness must be spread among people so that the misconceptions are minimized.