Best Antidepressants of 2018 – Expert Reviewed

Antidepressants

Facts about Antidepressants

The percentage of Americans taking antidepressants has nearly doubled between 1999 and 2012 according to a report published in Journal of the American Medical Association[1] (JAMA).

What this means is that more and more people are likely to try alternative remedies for their depression. And while antidepressants do help mitigate depression, they do come with their own set of side effects and risks.

According to an article published in the Harvard Mental Health Letter[2], antidepressants can make depressive symptoms even worse in the beginning and may even lead to adverse health outcomes.

Antidepressants reduce* the number of blood platelets which increases* a person’s risk of internal bleeding. Furthermore, when taking drugs or even herbs that increase* serotonin levels, antidepressant use may lead to serotonin syndrome which is a potentially fatal condition.

For all these and many other reasons, many depression sufferers are looking for other ways to fight depression and a potentially safe and effective way is by using natural antidepressant supplements.

Myths about Antidepressants

Natural antidepressants are made with ingredients such as herbs, amino acids, minerals, and vitamins that were scientifically proven to increase* the levels of serotonin in the brain. However, it’s a common myth that these types of treatments are completely safe just because they are natural.

Natural antidepressants are just as likely to cause side-effects as are prescribed antidepressants because they manipulate the levels of serotonin in the brain.

These changes in your brain chemistry caused by antidepressant use are the main reason why you may experience side effects and the case is the same with natural antidepressants. Another common myth with natural antidepressants is that they will make you feel happy.

Antidepressants work mainly by boosting serotonin levels in the brain which can make a person feel less anxious, less tired, and more energetic. But as far as happiness goes, antidepressants can only do so much

Myths about Antidepressants

How Do Antidepressants Work?

As already explained, antidepressants work mainly by boosting the levels of the neurotransmitter serotonin in the brain. Depression is considered, among other things, to be a result of chemical imbalances in the brain with low serotonin being the main culprit.

Although this theory no longer holds water, antidepressants paradoxically are able to mitigate the symptoms of depression which can help a person cope and recover more easily.

Studies show that antidepressants are effective in moderate and severe cases of depression[3], but not in milder cases.

Those suffering from mild depression may turn to natural antidepressants as a way to mitigate the symptoms associated with mood disorders such as panic attacks, anxiety, insomnia, low mood, low energy, and body aches.

Do Antidepressants Cause Side-Effects?

Several antidepressants have been associated with a risk of experiencing certain side-effects, which is something that people need to take into account when they are considering to start taking this medication to help them improve* their state-of-mind.

The safety and possibility of side-effects can be discussed with a professional healthcare provider, and when side-effects do appear, then the user can discuss this with their healthcare provider in order to change their dosage or the type of antidepressant they are using.

According to WebMD[4], common side-effects that people tend to experience when taking antidepressants include nausea, fatigue, drowsiness, dry mouth, constipation, an increase* in their appetite, weight gain, insomnia and, in some individuals, a significant reduction* in their sex drive.

Essential Facts while Choosing Antidepressants

When choosing a natural antidepressant, you should first talk to your doctor about the safety and efficiency of the product you are planning to use. If you are currently taking prescription antidepressants, you should be cautious about taking any other drug or supplement that could increase* the levels of serotonin in your body as this could lead to serotonin syndrome.

If, however, you are not taking any treatment for depression or other mood disturbances, you may try natural antidepressants as a safe alternative to prescription antidepressants. Just make sure that the product you are choosing is a reputable company to avoid ending up with adulterated and tainted supplements.

Mood Disturbances

Best Antidepressants of 2018

To help you fight depression naturally, we’ve compiled a list of the 10 best natural antidepressants and mood-enhancers of 2018. Make sure to read the complete reviews of these products to find a product you believe caters to your specific needs and problem.

#1 Serelax

Serelax

Serelax was developed by Pharmaxa-Labs to help fight depression and anxiety naturally. The product does not utilize any of the ingredients found in pharmaceutical drugs, but still has numerous benefits to offer the user. The product is said to improve* the levels of serotonin in the brain through its unique blend of natural ingredients.

Serelax is somewhat more expensive than some of the other similar products available on the market, but the high-quality ingredients found in the product makes it worth the price. A 30-day supply of Serelax costs $34.50. The product can only be purchased at the official website of the product.

The product claims to assist with calming down the user’s central nervous system, as well as to help the body produce more serotonin naturally, which will assist with boosting the user’s mood.

The ingredients found in Serelax include gamma-Aminobutyric acid (GABA), L-Theanine, passionflower, kava kava, valerian, jujube, skullcap, chamomile, and Griffonia simplicifolia bean extract. It is important to take Serelax according to the dosage instructions provided by the manufacturer – when these instructions are closely followed, the product will not cause the user to experience any side-effects.

Click here to learn more about Serelax.

#2 Anti-Anxiety Plus

Anti-Anxiety Plus

Anxiety Plus is a dietary supplement that only relies on organic substances that are extracted from natural sources. The product has been produced to assist the consumers to get rid of stress and anxiety.

It’s manufactured from a combination of natural ingredients, which have all been tested through scientific studies and trials in order to proof their efficiency in relieving the symptoms associated with depression, as well as to provide a significant reduction* in stress and anxiety symptoms.

This formula functions by enhancing* the development of certain hormones in the user’s body, thus helping to the user to have improved* moods and less stress. It’s said to be a fast acting supplement, which means the user will be able to experience the effects of the supplement soon after they take it. The product is also considered to be very safe, which means the user is not expected to experience any side-effects.

Vitabalance is the company behind the production of this supplement. This supplement is made available online and can be purchased from the company’s official website. A bottle of this supplement goes for about $40.00, and it’s said to have discount offers.

Click here to learn more about Anxiety Plus.

#3 Symetrin

Symetrin

Symetrin is a natural anti-depressant that is primarily being promoted as a mood enhancer. The product is mainly promoted to a female audience. The manufacturer of Symetrin claims that the product will not only help to provide the female user with a significant boost* in their mood but also help to reduce* the mental symptoms that comes during PMS and menopause.

The product contains patented formulas that were clinically tested for their safety and efficiency, namely Sensoril and Libefem. Sensoril contains the herb Ashwagandha that a clinical study published in the Journal of Alternative and Complementary Medicine[5] found to be effective in reducing* stress and anxiety.

Libifem is a specialized extract of the Trigonella foenum-graecum Seed Extract herb that a clinical trial published in Phytotherapy[6] Research found improved* hormonal balance in women and also increased libido and sexual functioning. Symetrin also contains two other ingredients, vitamin B6 and vitamin D which are two of the most important vitamins for normal mood regulation and nervous system functioning.

Symetrin comes with a 30-day free trial and no side-effects have been associated with this natural antidepressant. The product does not contain any ingredients that may cause addiction and this is one of the few supplements on the market that holds scientific evidence to back up the claims made about the product.

Click here to learn more about Symetrin.

#4 A2X

A2X

A2X is another natural anti-anxiety and depression relief supplement that is manufactured and sold by the company of the same name. A2x has become quite popular amongst individuals who prefer to turn to natural products to help them reduce* the symptoms they experience due to depression and anxiety disorders.

The product contains a couple of serotonin-boosting ingredients such as Passionflower, Ashwagandha, L-Theanine, Vitamins B12 and B6, and the minerals calcium and magnesium. Passionflower is believed to increase* GABA currents in the brain and as such work as an anxiolytic treatment.

L-Theanine is a compound found in tea and that studies found that it was able to relax the mind without causing drowsiness. The vitamins B12 and B6 are important precursors for neurotransmitter synthesis and the support brain health in general. Calcium and magnesium are also important nutrients for normal brain signaling.

A2X can be more expensive than some of the other options available for individuals looking to buy a natural antidepressant, but the product does come with a 30-day trial period, allowing a customer to buy and try the product, then return it to the manufacturer for a refund if they are not happy with the results.

Click here to learn more about A2X.

#5 Zanaprin

Zanaprin

Zanaprin is manufactured by a company called Lazarus Labs which is a fairly well-known company in the supplement industry. Lazarus Labs manufactures a wide variety of natural supplements, with Zanaprin being a particularly popular product from this company.

The product was designed to help with social anxiety, stress, insomnia, panic attacks and it is said to increase* mental alertness and cognitive functioning. This makes Zanaprin an all-in-one solution for individuals who experiences problems with their mental wellbeing.

This product contains only natural ingredients, making it a safer solution than some of the pharmaceutical options that are available to individuals suffering from the symptoms that the supplement claims to treat*.

The main ingredient in this product is phenibut (beta-phenyl-gamma-aminobutyric acid) whose mechanisms are similar to GABA, meaning that it works by calming the central nervous system. Even though many of the ingredients have shown promising results in clinical trials, it should be noted that the product may not work for everyone – a number of unsatisfied customer testimonials can be found on product listings where Zanaprin is sold on the internet.

There are, however, some positive reviews that claim the product is effective in providing the particular benefits claimed by the manufacturer. Thus, those suffering from mild anxiety and depression could benefit from this unique treatment.

Click here to learn more about Zanaprin.

Taking Depression Pill

#6 Stresstabs

Stresstabs

Stresstabs is a nutritional supplement product said to support normal brain functioning with its blend of important nutrients. The product claims to provide a significant number of benefits to the user, and the manufacturer of Stresstabs claim that the product works relatively fast, making it perfect for individuals who often find themselves in stressful situations.

The ingredients in this product are vitamins C, E, thiamine, riboflavin, niacin, B6, folate, B12, biotin, B5, and the minerals calcium, magnesium, phosphorus, zinc, and copper. These vitamins and minerals were added to the Stresstabs formula because research shows that they are of crucial importance for normal brain signaling, DNA synthesis, and neurotransmitter production.

This product is completely safe to use even if you are taking antidepressants as it won’t have a significant impact on the functionality of neurotransmitters in the user’s brain. The product is perfect if you are looking for a formula that will support your brain’s health for better stress relief and sleep.

Another great thing about this product is that it is pretty affordable, coming at a price of only $5.37 which is a fraction of the price of other mood-enhancing supplements.

Click here to learn more about Stresstabs.

#7 Tranquilene

Tranquilene

Tranquilene is an all-natural antidepressant manufactured by Tranquility Labs LLC, a company based in the United States. The company has included a large number of ingredients in the Tranquilene formula for maximum product efficiency – all of these ingredients come from natural origins and no potentially harmful chemical compounds are added to the Tranquilene formula.

The product is powerful in its ability to reduce* stress and anxiety and can even lead to drowsiness if taken above the recommended dose – for this reason, users are recommended to follow the dosage instructions offered on the container of the product to avoid experiencing sedative side-effects.

The ingredients in this product are mainly botanicals such as Passionflower and Ashwagandha. Both of these ingredients have been proven through scientific studies to offer a significant boost* in the production of serotonin, as well as to help calm down the user’s central nervous system, which helps to provide a calmer state-of-mind and reduce* anxiety-related symptoms noticeably.

Tranquilene also claims to help boost* the user’s mood – low moods are very common amongst individuals suffering from depression. Tranquilene can be purchased from the official website of the product’s manufacturer, and a money-back guarantee is offered for those individuals who are unsure whether or not the product would work effectively for them.

Click here to learn more about Tranquilene.

#8 Nuphorin

Nuphorin

Unlike most other mood-enhancing supplements that require a long time of consistent use to provide any benefits, Nuphorin works almost instantly. This is one of the primary reasons why a lot of people opt for Nuphorin.

This characteristic makes this product a perfect option for anyone suffering from severe anxiety and panic attacks, which often tend to occur at unexpected times – when these symptoms develop, the user can take Nuphorin to experience its benefits in a relatively short period of time.

Nuphorin is an all-natural dietary supplement that does not cause side-effects that could put the user’s health in danger, and only natural substances are included in this product’s formula.

One of the most significant issues that individuals have with Nuphorin is the product’s price. Nuphorin costs $199.99 per bottle, which provides an adequate supply for 30 days. This means that Nuphorin is one of the most expensive natural antidepressants currently available on the market.

There are, however, a lot of positive reviews that claim the product works very fast and the supplement is very effective in reducing* anxiety and stress levels. Nuphorin is available from the product’s official website, but can also be purchased on Amazon, making it easier to obtain the product.

Click here to learn more about Nuphorin.

#9 Gabatrol

Gabatrol

Unlike most other mood-enhancing supplements that require a long time of consistent use to provide any benefits, Nuphorin works almost instantly. This is one of the primary reasons why a lot of people opt for Nuphorin.

This characteristic makes this product a perfect option for anyone suffering from severe anxiety and panic attacks, which often tend to occur at unexpected times – when these symptoms develop, the user can take Nuphorin to experience its benefits in a relatively short period of time.

Nuphorin is an all-natural dietary supplement that does not cause side-effects that could put the user’s health in danger, and only natural substances are included in this product’s formula.

One of the most significant issues that individuals have with Nuphorin is the product’s price. Nuphorin costs $199.99 per bottle, which provides an adequate supply for 30 days. This means that Nuphorin is one of the most expensive natural antidepressants currently available on the market.

There are, however, a lot of positive reviews that claim the product works very fast and the supplement is very effective in reducing* anxiety and stress levels. Nuphorin is available from the product’s official website, but can also be purchased on Amazon, making it easier to obtain the product.

Click here to learn more about Gabatrol.

#10 Relora

Relora

Relora works mainly by controlling your stress levels and we know that stress is the number one cause of both anxiety and depression. The product works mainly by controlling the release of cortisol which is the main stress-response hormone. High levels of cortisol has been linked to a number of health conditions – not only depression and other mental disorders, but also certain physical health concerns.

Relora is one of the more affordable options on the market for individuals looking to buy a natural alternative to pharmaceutical options that are developed to treat* antidepressants. Relora can be purchased for $11 – this amount provides the customer with a one-month supply of the product.

The two key ingredients in this product are the herbs Magnolia Officinalis and Phellodendron amurense bark. These plants contain powerful antioxidants that are believed to help with normal brain functioning and stress adjustment.

The manufacturer of Relora claims that the product does not cause side-effects, mostly due to the fact that the ingredients of the product are natural extracts. It should be noted, however, that some reviews have reported experiencing an upset stomach and dizziness after taking the product.

Click here to learn more about Relora.

#11 True Calm

True Calm

True Calm is manufactured by a reputable supplement manufacturer, namely Now Foods. Now Foods have a range of different products on the market, and the majority of their products are very popular amongst individuals who prefer natural supplements over pharmaceutical options. The product contains no ingredients that could lead to serious side-effects, and, unlike SSRI’s, this product will not cause a reduction* in the user’s sex drive.

The main ingredient of True Calm includes Gamma-Aminobutyric Acid, more commonly known as GABA. This ingredient is a natural amino acid that is already found in the body – it is also known as a neurotransmitter.

This particular neurotransmitter is known to have a significant role to play in stress levels – by supplementing the body with additional levels of the substance, the user may experience a considerable relief in stress levels. Apart from GABA, True Calm also contains Vitamin B6, Niacin, Magnesium, Taurine, and Glycine.

The product is affordable, with a price tag of $13.99. The manufacturer of Ture Calm also offers a guarantee on the product that allows the customer to request a refund if they do not feel that the product is providing them with the benefits the manufacturer claims the product can provide.

Click here to learn more about True Calm.

Conclusion

Antidepressants are types of drugs that research has yet to show has any effect on depression. What we do know is that they do help with severe cases of depression but not with milder ones. Natural antidepressants usually work through the same mechanisms as do prescription antidepressants -by boosting the levels of serotonin in the brain. But natural antidepressants have an additional advantage of addressing other issues that may be causing depression besides low serotonin levels.

Many of these natural antidepressants, for instance, mitigate stress, anxiety, insomnia, and nutritional deficiencies. All these factors could be at the root of depression. The natural antidepressants reviewed here are good examples of products that address depression from multiple angles.

These products reduce* stress, central nervous system activity, cortisol release, and enhance* brain neurotransmitter synthesis and support overall brain health. All this makes natural antidepressants a better and safer alternative to fighting depression.

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

Disclosure of Material connection: Some of the links in the post above are "associate sales links."This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

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Author

Contributor : Dr. Ahmed Zayed (Consumer Health Digest)

Dr. Ahmed Zayed Helmy holds a baccalaureate of Medicine and Surgery. He has completed his degree in 2011 at the University of Alexandria, Egypt. Dr. Ahmed believes in providing knowledgeable information to readers. Other than his passion for writing, currently he is working as a Plastic surgeon and is doing his masters at Ain shams University.

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