Newest Nootropic Brain Ingredients to Look for in 2017

Newest Nootropic Brain Ingredients
Editor's Note: This article has been recently updated with latest information and research studies.

The use of supplements has increased significantly lately. It became perfectly normal to use these products to improve* fitness performance, sexual health, relieve joint pain, and to improve* cognitive abilities at the same time. An increasing* number of people use nootropics and the best thing is; you can find them in stores or purchase online. In this article, we bring you the list of ingredients to look for in nootropics this year.

What are Nootropics?

Nootropics is an umbrella term that refers to either naturally occurring or manmade chemicals that provide cognitive benefits to the human brain. Dr. Corneliu E. Giurgea, the Romanian psychologist, and chemist, coined the term and created the criteria that substances should meet in order to be classified as nootropics. They are:

  • Enhance* memory and ability to learn
  • Have only a few or no side effects at all, the substance should be virtually non-toxic
  • Improve* brain function under disruptive conditions such as electroconvulsive shock and hypoxia or low oxygen
  • Improve* the efficacy of neuronal firing control* mechanisms in subcortical and cortical regions
  • Protect* the brain from physical and chemical assaults

As you can see, nootropics should be beneficial for different aspects of cognitive function and safe for general consumption. Manufacturers use a variety of ingredients with brain-boosting benefits. These are the substances you should look for on the product label in 2017.

Nootropics Intro

1. Cacao

Cacao is the purest form of chocolate one can consume; it’s raw and not heavily processed. With high antioxidant and flavonoid content, it comes as no wonder* why a wide array of nootropics contain cacao in the formula. For example, the American Journal of Clinical Nutrition published results of the study which showed that the habitual intake of raw cocoa supports* healthy cognitive function with age.

Related: Aerobic Exercise Improves* Cognitive Function in Old Age

Scientists at the Columbia University discovered that dietary cocoa flavanols have a tremendous potential to reverse* age-related memory decline. Also, it’s important to mention that this ingredient offsets the undesirable adverse effects of caffeine on cerebral blood flow. Benefits of cacao are exerted through a set of mechanisms such as vasodilation, anti-inflammatory effects, antioxidant properties, and neuroprotective role.

2. CDP Choline

CDP Choline

CDP-choline is a nootropic compound that converts to both choline and cytidine upon ingestion. The latter converts to uridine in the organism. Researchers at the Boston University School of Medicine carried out a study which showed that higher choline consumption was strongly associated with better* cognitive performance.

Moreover, there’s evidence that choline supplementation facilitates the consolidation of short-term into long-term memory while a research from the Behavioral Brain Research showed that choline improves* attention.

3. Rhodiola Rosea

Rhodiola rosea is a herb touted to promote physical and cognitive vitality. It acts through the process of neurogenesis and formation of neuropeptides Y, COMT, and MAO. One research showed that rhodiola rosea improves* serotonin levels; meaning it also helps improve* mood in depressive individuals. The same study also revealed that the herb induces neural stem cell proliferation at hippocampus to return to normal level and repairs injured neurons.

Rhodiola rosea also proved highly effective in individuals who suffer from physical and cognitive deficiencies. There are some indications that this herb relieves* both mental and physical fatigue, but more studies are necessary on this subject to inspect the matter thoroughly.

4. Armodafinil

Armodafinil also referred to as Nuvigil, significantly improved* quality of episodic secondary memory and participants’ ability to engage in activities of daily living, found the research from the Sleep & Breathing. The substance also reduced* fatigue.

Armodafinil improves* motivation, arousal, and enhances* vigilance. What most people don’t know is that this ingredient also acts as an appetite suppressant which is why athletes and professional bodybuilders use it to maintain their weight and improve* athletic performance through anti-fatigue effects and wakefulness.

Anti Fatigue

5. Coluracetam

Coluracetam was invented in Japan with the purpose of providing a major boost* to cognitive functions. The substance works by increasing* choline uptake into neurons, even if they’re already damaged or impaired. As mentioned above, choline plays a major role in the improvement of cognitive abilities. Coluracetam improves* memory, especially in memory-impaired individuals. Besides memory, this nootropic helps manage decreases* the severity of depression symptoms and anxiety.

6. NSI-189 phosphate

NSI-189 phosphate is a pharmaceutical nicotinamide that is primarily created to relieve anxiety and depression. While studies on this subject are still ongoing, there’s evidence that the substance shows potential as a treatment for major depressive disorder as participants experienced improvements in cognitive and depressive symptoms.


Ideal nootropics are the ones that have a tremendous ability to improve* memory, learning, and other aspects of cognitive functioning as well as to relieve stress, anxiety, depression and so on. When looking for supplements, it’s always practical to opt for those whose benefits are well-documented.



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Expert Author : Dr. Ahmed Zayed (Consumer Health Digest)

Dr. Ahmed Zayed Helmy holds a baccalaureate of Medicine and Surgery. He has completed his degree in 2011 at the University of Alexandria, Egypt. Dr. Ahmed believes in providing knowledgeable information to readers. Other than his passion for writing, currently he is working as a Plastic surgeon and is doing his masters at Ain shams University.