Prevagen Review: Does It Really Work and Is It Safe To Use?

Prevagen is the leading memory support and brain health supplement in America that promise to enhance overall brain health. Learn the Science behind Prevagen.

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In This Review

Overview of Prevagen

Prevagen stands out as America’s leading supplement for memory support and brain health. Many wonder if it truly works and if it’s safe. In a world where forgetting small details becomes more common, Prevagen promises a solution. It aims to sharpen your memory and boost your brain’s overall health.

People across different stages of life face challenges with memory and focus. From students struggling to retain information to adults juggling work and personal life, the need for a reliable solution is evident. The worry about memory loss or mental fog affects many, hindering their daily performance and quality of life.

Using Prevagen brings promising results. It’s not just about enhancing memory; it’s about experiencing clearer thinking and improved cognitive performance. Imagine a daily life where facts stick easily, and tasks get completed without the cloud of forgetfulness. Prevagen, with its blend of unique ingredients, aims to make this a reality for its users.

This article dives into the science behind Prevagen, highlighting how it works and what makes it stand out. Whether you’re curious about its effectiveness or wondering about potential side effects, we’ve got you covered. You’ll learn about the key ingredients, the research backing the product, and real users’ experiences. It’s a comprehensive look at a supplement that promises to revolutionize brain health.

What is Prevagen?

Prevagen is a dietary supplement designed with brain health in mind. Launched in 2007, it has become a popular choice for those looking to enhance their memory and cognitive abilities. Its formula is centered around apoaequorin, a protein originally discovered in jellyfish, and it’s complemented by other brain-supportive nutrients like Vitamin D.

At its core, Prevagen addresses the common issue of cognitive decline related to aging. It’s not unusual for people to notice a dip in their memory or focus as they get older. Prevagen’s unique formula aims to combat these changes, offering a beacon of hope for maintaining mental clarity well into the later stages of life.

The effectiveness of Prevagen lies in its ingredients. Vitamin D is known for its role in brain health, supporting nerve growth and reducing inflammation. Apoaequorin, the star component, has shown promise in improving memory and cognitive function, although research continues to explore its full potential. Together, these ingredients work to support overall brain function and health.

Understanding how Prevagen works is crucial for anyone considering it as a supplement. By targeting the brain’s need for calcium binding proteins and providing vital nutrients, Prevagen aims to enhance cognitive functions. It’s a daily supplement that fits easily into your morning routine, promising to deliver noticeable improvements in memory and focus.

How Does Prevagen Rate?

Overall Rating: 3.8

Value for Cost

3.5/5Value for Cost
Return Policy

3.6/5Return Policy
Reliable Reviews

3.9/5Reliable Reviews

Brand Highlights

  • Prevagen has been certified by NSF’s Contents Certified program, ensuring consumers that it is safe and reliable.
  • Since 2007, Prevagen has earned trust from over 10 million satisfied customers worldwide, with millions of bottles sold.
  • Pharmacists have chosen Prevagen as the top choice for five consecutive years, reflecting its trusted reputation.



*All individuals are unique. Your results can and will vary.

Key Ingredients

  • Apoaequorin
  • Vitamin D
  • Calcium
  • Phosphorus


  • It could greatly enhance memory.
  • This product may help you think clearer.
  • There are mild potential side effects.
  • It may help memory loss caused by aging.
  • The product might strengthen cognitive performance.
  • You only to take one small capsule daily.


  • This is an expensive supplement.
  • You may have side effects like stomach upset and diarrhea.

How Does Prevagen Work?

There are 2 primary active ingredients in Prevagen. Vitamin D is important in nerve growth and synthesis in the brain. There are numerous Vitamin D receptors in the brain. In addition, it plays a neuroprotective role according to an article in Cureus [1]. Low Vitamin D can put you at risk for developing dementia.

Apoaequorin comes from a jellyfish, and many people believe it has an impact on memory and verbal learning. However, there’s not a lot of research as of yet. It’s a protein which binds to calcium, and this property may cause its brain-enhancing benefits. A study on adult and aging rats in Brain and Behavior found that this substance modulates fear memory [2].

Prevagen Ingredients – Are they Safe & Effective?

These are the primary active Prevagen ingredients:


– This is a protein taken from a glowing jellyfish. It has the ability to bind to calcium, which may be responsible for its role in brain health. This substance is thought to especially improve memory, but there’s only a small amount of research supporting this right now.

A study published in Advances in Mind and Body Medicine found that apoaequorin improved verbal learning in older adults[3].

Prevage Supplement Facts
Prevage Supplement Facts

Vitamin D

– This vitamin is made in your skin when you go out into the sunlight, and you can also get it from food. It protects the brain and can reduce inflammation. In addition, it plays a key role in brain nerve synthesis.

There’s some evidence that low levels of this vitamin can lead to dementia. An article in Practical Neurology explored the cognitive consequences of Vitamin D deficiency [4].


– This is an essential mineral that strengthens our bones and teeth, helps the blood clot, keeps the heart beating, and allows muscles to contract. It plays a key role in the brain, affecting memory and neurotransmitter function.

An article published in General Pharmacology examined the role of calcium in brain aging [5].


– This is a chemical element that is the second most common mineral in the human body. Some of it is found in the bones, and it supports bone health. There’s plenty of phosphorus in the brain, and it’s important in controlling many bodily processes.

A study in Frontiers in Aging Neuroscience found a correlation between low levels of phosphorus and cognitive impairment [6].

Other Products Offered by Prevagen

Here are the basic products available:

  1. Prevagen Regular Strength 30 Capsules

  2. A regular strength nootropic which can sharpen the mind, improve memory, and enhance focus.

    Ingredients: Apoaequorin, Vitamin D


    • This product may sharpen your mind.
    • Clinical research has shown its effectiveness.
    • You may experience mild side effects.
  3. Prevagen Regular Strength 60 Capsules

  4. A regular strength nootropic which can sharpen the mind, improve memory, and enhance focus.

    Ingredients: Apoaequorin, Vitamin D


    • It could greatly enhance memory.
    • This product may help you think clearer.
    • There are mild potential side effects.
  5. Prevagen Extra Strength 30 capsules

  6. This is a more potent version of the regular strength product. It can strengthen memory, attention span, and cognitive performance.

    Ingredients: Apoaequorin, Vitamin D


    • This supplement may enhance your mental focus.
    • It might improve overall brain health.
    • One bottle gives you a 60-day supply.
  7. Prevagen Extra Strength 60 capsules

  8. This is a more potent version of the regular strength product. It can strengthen memory, attention span, and cognitive performance.

    Ingredients: Apoaequorin, Vitamin D


    • It may help memory loss caused by aging.
    • The product might strengthen cognitive performance.
    • You only to take one small capsule daily.
  9. Prevagen Chewables: Mixed Berry Flavor 30 Capsules, 10 mg

  10. A chewable version of the regular strength product.

    Ingredients: Apoaequorin, Vitamin D

    How to Use: Take one of these capsules daily in the morning, either with or without food. Chew slowly and swallow. Follow up with a glass of water.

  11. Prevagen Chewables: Mixed Berry Flavor 30 Capsules, 20 mg

  12. A chewable version of the regular strength product.

    Ingredients: Apoaequorin, Vitamin D

    How to Use: Chew one tablet in the morning and swallow. Drink a glass of water afterwards. You can take the capsules with or without food.

  13. Prevagen Regular Strength Chewables, Orange 30 Capsules

  14. This is the regular strength product in chewable form, with an orange flavor.

    Ingredients: Apoaequorin, Vitamin D

    How to Use: It’s best if you take one capsule in the morning, with or without breakfast. Chew it and then swallow and have a glass of water afterwards.

  15. Prevagen Professional Formula 30 Capsules

  16. This supplement particularly focuses on improving brain function and sharpening the mind.

    Ingredients: Apoaequorin, Vitamin D


    • This product can greatly enhance mental functioning.
    • It can help people with mild cognitive impairment.
    • The supplement can improve age-related memory loss.
  17. Neuroshake 15 Packets

  18. A nootropic product in the form of a low fat, tasty shake.

    Ingredients: Calcium, Phosphorus


    • It may provide your brain with important nutrients.
    • This product may have powerful anti-aging effects.
    • It may help build muscle and improve cognitive performance.

Alternatives to Prevagen


Claritox Pro

*All individuals are unique. Your results can and will vary.

Prevagen Review – FAQ’s

Q: How Much is Prevagen and Where Do I Buy It?

A: You can buy the Prevagen products on Prevagen Amazon, eBay, Prevagen at Walmart, and the official website. They are likely some other retailers who sell it as well. The Prevagen cost of the products on the official website are as follows:

  • Prevagen Regular Strength 60 Capsules – $74.95
  • Prevagen Extra Strength 60 Capsules – $109.95
  • Prevagen Chewables: Mixed Berry Flavor 30 Capsules, 10 mg – $39.95
  • Prevagen Regular Strength 30 Capsules – $39.95
  • Prevagen Extra Strength 30 Capsules – $59.95
  • Prevagen Chewables: Mixed Berry Flavor 30 Capsules, 20 mg – $59.95
  • Prevagen Regular Strength Chewables, Orange – $39.95
  • Prevagen Professional Formula 30 Capsules – $89.95
  • Neuroshake, 15 Packets – $19.95

Q: Can Prevagen Improve Memory?

A: Prevagen claims that their products contain ingredients which can enhance brain health, particularly memory. The primary ingredient, apoaequorin, does not have a lot of research linking it with memory, but there have been some positive studies.

ALSO READCerebra and Neuronol

Q: How Do I Take Prevagen?

A: All of the Prevagen products for memory have a recommended dose of one capsule per day. The exception is the Neuro Shake, where you mix a packet with 8 ounces of water and drink it once a day.

Q: How Long Does Prevagen Take to Work?

A: According to the manufacturer, it takes about 90 days to fully see the results of Prevagen pills. However, you may begin to notice some changes along the way.

Q: Do I Need a Prescription for Prevagen?

A: There’s no reason for Prevagen pills to be prescribed by a doctor. This is an over-the-counter product that you purchase either online or offline at locations like Walmart. Despite this, you should still get approval from your doctor before using this supplement.

Q: Can Prevagen be Harmful?

A: Generally speaking, Prevagen is a safe product which only leads to mild potential Prevagen side effects, There have been a very small number of heart and nervous system issues with apoaequorin, but this is extremely rare.

There are a few medical conditions that preclude taking too much Vitamin D, including kidney disease, lymphoma, arteriosclerosis, hyperparathyroidism, high calcium in the blood, and tuberculosis.

If you have allergies, it’s important to check the Prevagen ingredients list carefully to make sure the product is suitable for you.

Q: Can Prevagen Help with Dementia?

A: Prevagen contains Vitamin D, which can help with dementia. Research in BMC Neurology indicates that a deficiency in Vitamin D puts you at higher risk for developing Alzheimer’s disease [7]. However, the amount of the vitamin in Prevagen is not very high, so it may not be overly effective for dementia. The manufacturer does claim that Prevagen can help with mild cognitive function.

Q: What is the Return Policy for Prevagen?

A: The manufacturer has a 45-day return policy for Prevagen. If you are not happy with the item, contact customer service and then send the product back within 45 days of the original purchase date. You will get a full refund.

Q: Can Prevagen Be Taken with Other Meds?

A: Apoaequorin has no contraindications with any medications, but Vitamin D does have some possible issues. Before you take Prevagen, speak to your doctor and make sure the product you chose is suitable for you.

Q: What Do the Reviewers Think of Prevagen?

A: The Prevagen reviews were quite positive overall. The majority of users said this product improved their memory, focus, and cognitive performance. There were a few complaints from customers who had side effects or didn’t find the product effective.

Q: What Are the Benefits of Prevagen?


  • Prevagen could improve your memory.
  • It may support overall brain function.
  • The product might give you clearer thinking.
  • Prevagen could give you a sharper mind.
  • This product may be easy to swallow.

Q: What Are the Side Effects of Prevagen?

A: There are a few mild side effects that may occur as a result of using the product. For example, apoaequorin may lead to symptoms like headaches, nausea, or dizziness. Less commonly, anxiety and difficulty sleeping.

Vitamin D only has side effects if you take too much. These may include headache, dry mouth, loss of appetite, nausea, vomiting, fatigue, weakness, sleepiness, or a metallic taste.

Q: How Do the Prevagen Products Compare to Other Nootropic Supplements?

A: The Prevagen line is expensive and higher than most similar brain enhancement supplements. In terms of ingredients, most of the supplements only have 2 primary active substances, which is much less than other nootropic supplements on the market.

It seems to be missing some popular ingredients. However, the Prevagen reviews had mostly very good things to say about this product line.

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What Do the Prevagen Reviews Say?

Prevagen reviews often praise its purported ability to support brain health and cognitive function, with many users reporting positive effects on memory and focus. However, some reviewers question its efficacy, pointing out the absence of robust scientific evidence and emphasizing that individual experiences may differ.

“I have been using Prevagen for about 5 months and SF180 Brain really works for my husband. It helps to improved focus and concentartion.”- hazel

One user from Amazon said, “I tried Prevagen for 6 months and was not sure if it worked. I stopped using it and did not notice any difference.”

Another user said, “I took Prevagen for 30 days, but unfortunately, I wasn’t able to determine if it actually improves anything. It may, but I don’t think I’m up to buying 3 months’ worth to find out. My expectations may simply be too high. It would be good if there were some sort of cognitive test that might provide some insight into improvement, but I imagine that is hard to develop because we are all different. I may try again at some future time.”



*All individuals are unique. Your results can and will vary.

Prevagen Review – Conclusion

Prevagen is a line of natural supplements which promises to enhance brain health, memory, focus, mental sharpness, and clearer thinking. It contains only 2 primary active ingredients and seems to be missing some popular substances. These products are somewhat costly.

The Prevagen review postings are very positive. The vast majority of users said they got great results from Prevagen for mental clarity, improvements in memory, thinking, and overall cognitive performance. There were a smaller number of customers who didn’t find the supplements effective.

There is a chance of adverse reactions to Prevagen. If you do have unpleasant symptoms, discontinue the use of the supplement. Before you start taking Prevagen, see a doctor and get medical approval.

More than ever people of all ages are struggling with memory problems. People are unable to disconnect from their work, while students are under immense pressure to perform. Brains are overloaded with information that must be remembered. A quality memory enhancement product might contain clinically proven ingredients that will help to enhance not only memory, but also focus and night concentration. Memory products might help to optimize overall mental health and brain function.

Below you'll find some of the most effective memory products on the market today, in our opinion.

Our Top Memory Supplements

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned brain health supplements and nootropic based on the available research:

Noocube | Premium Brain Productivity Supplement
Strengthen Memory*Gold Star Evidence
Boost Memory & Mental Alertness*Gold Star Evidence
Improve Concentration*Gold Star Evidence
Improve Focus & Mood*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Nootrogen | Nutritional Nootropic Brain Support
Supports Memory*Gold Star Evidence
Supports Cognition*Strong Evidence
Improve Focus*Gold Star Evidence
Supports Stress*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Claritox Pro | Vertigo Support Supplement
Boosts Brain Function*Gold Star Evidence
Strengthens Focus and Clarity*Gold Star Evidence
Improves Cognitive Health*Strong Evidence
Reduces Stress and Anxiety*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Zenith Labs Brain C-13 | Advanced Brain Health Support
Promotes Memory*Gold Star Evidence
Supports Quick Thinking*Strong Evidence
Boosts Energy*Gold Star Evidence
Helps Awareness*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Prevagen

Prevagen Review: Does It Really Work and Is It Safe To Use?

Customer Reviews & Ratings

1.0 out of 5

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  1. James

    Tried to give the benefit of the doubt to the product.
    I purchased and tried Prevagen for about a year and did not notice an improvement in cognitive abilities. I even bought Prevagen extra strength to see if it would help and still found that I had to search for and try to remember words and names I once used regularly.

    It is expensive, and I hoped that the advertising was true. It wasn’t.

  2. Robert Bryngelson

    Worthless hype and efficacy
    An expensive waste of money. Both my wife (84) and I (80) have tried regular and increased strength doses of Prevagen daily for the last two months with no measurable impact on our cognitive abilities or recall. And, in my opinion, this is just another snake oil on the market that is worthless.

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Prevagen Ques and Ans

  • Q: Can a doctor write a scrip for me?

    A: You can ask your doctor if this is the right supplement for you and if it is he will prescribe it.

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Apoaequorin, Vitamin D, Calcium and Phosphorus

7 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Article in Cureus :
[2] Apoaequorin differentially modulates fear memory in adult and aged rats :
[3] Effects of a Supplement Containing Apoaequorin :
[4] Cognitive Consequences of Vitamin D Deficiency :
[5] Role of calcium in brain aging :
[6] Low Serum Phosphorus Correlates :
[7] Vitamin D deficiency :

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

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