Neuro-Mag Review: Does It Really Work as Advertised?

NeuroMag is a magnesium supplement that promises to enhance mood and energy and support healthy memory and youthful cognitive function.

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In This Review

Overview of Neuro-Mag

Research has shown that higher dietary Magnesium intake is related to better brain health in the general population, and this is especially true for women. It comes as no surprise that in this current day and age, many people now understand the importance of vitamin and mineral supplements for healthy people and people with chronic conditions. This is why many kinds of supplements, including magnesium supplements, have flooded the market, making it hard to distinguish between the real deal and the fakes.

Life Extension has positioned itself as an industry leader in the supplement industry and promises that one of its bestselling products, Neuro-Mag, can help support healthy memory and youthful cognitive function with easily digestible magnesium.

In this review, we tell you all you need to know about Neuro-Mag in order to make an informed buying decision. We explore everything from the ingredients to the brand, scientific research on the ingredients, potential side-effects, money-back guarantee, and most importantly, effectiveness.

How Does Neuro-Mag Rate?

Overall Rating: 3.8

Value for Cost

3.7/5Value for Cost
Return Policy

3.9/5Return Policy


Brand Highlights

  • Life Extension is a well-established brand in the supplements market.
  • Life Extension has a responsive customer care team.
  • Neuro-Mag and Other product made by Life Extension has mostly positive reviews.
  • Life Extension has a respectable number of positively reviewed products on its resume.
  • Has a working money-back/product exchange policy.

Key Ingredients

  • Magnesium (synthesized from 200mg Magtein magnesium L-threonate) 144 mg
  • Vegetable Cellulose (Capsule)
  • Microcrystalline Cellulose
  • Stearic Acid
  • Silica
  • Vegetable Stearate


  • Many reviews say Neuro-Mag does not cause the typical nausea associated with other magnesium supplements.
  • Many Neuro-Mag Amazon reviews credit it for helping people sleep better.
  • The product works as promised for most people.
  • The product has higher-than-average bioavailability.
  • The parent company is a trusted brand in the supplements industry.


  • A small percentage of people still complained of nausea.
  • One review complained about the capsule size being too big.



*All individuals are unique. Your results can and will vary.

What is Neuro-Mag?

Neuro-Mag is a dietary Magnesium supplement made by Life Extension that combines mineral magnesium with other nutrients in an effort to support brain health. Life Extension says Neuro-Mag is designed to help with cognitive function and support overall brain wellness due to its Magnesium content, which is known to support brain function and prevent/improve neurodegenerative diseases.

Several studies have shown that magnesium is an essential mineral in the body that plays a vital role in nerve transmission and neuromuscular conduction. Neuro-Mag is made up of Magtein (magnesium l-threonate), a form of magnesium compound believed to be particularly effective at increasing magnesium levels in the brain[1].

The potential benefits of Neuro-Mag, according to the Life Extension website, include improved memory, cognition, and mood regulation.

The main ingredient found in Neuro-Mag is Magtein (magnesium l-threonate), a proprietary form of magnesium. The brain-protecting effect that Magtein offers is the main selling point of Neuro-Mag, which makes it a potentially compelling product for anyone looking to improve their cognition and protect their brain from neurodegenerative diseases[2].

Who is the Manufacturer of Neuro-Mag?

Life Extension is a well-established brand in the dietary supplement industry. Life Extension is popular for delivering products that people enjoy and its commitment to science-based health solutions and research on longevity. The brand says it has been in business for more than 40 years and has close to 500 employees.

Life Extension has its headquarters and a retail store in Fort Lauderdale, Florida. The brand also has a call center in Las Vegas and a manufacturing/shipping facility in New Jersey.

According to Life Extension’s website, the brand has a diverse team of experts, which includes doctors, nutritionists, and nurses that customers can talk to and consult with when trying to find the best supplement for their bodies.
Life Extension also mentions on its website that 99% of its products are manufactured in the United States using pure and potent ingredients sourced from around the world.

Note: We recommend that you always talk with your doctor or dietician before trying any supplement, especially if you have an underlying illness or drug sensitivity.

According to the reviews from some of the customers who have tried their supplement products on Amazon, some of the reasons they choose products from Life Extension include:

  • Life Extension’s credibility as a brand that prides itself on carrying out proper research on its products.
  • Life Extension has a history of strict quality control standards throughout the manufacturing process, making sure their products work as promised. When customers have problems with their products, their customer care representatives are always ready to help.
  • Life Extension has an extensive list of products that their customers love and trust to work as promised.
  • The summary of it all is that Life Extension is a trusted brand.


Claritox Pro

*All individuals are unique. Your results can and will vary.

How Does Neuro-Mag Work?

Neuro-Mag is essentially a magnesium supplement that is absorbed more easily by the brain due to it deriving its magnesium from Magtein (magnesium l-threonate), a proprietary form of magnesium that has been shown to help improve cognitive functions and improve brain health.

Even though magnesium is one of the most abundant essential minerals in the body, most magnesium supplements typically have low bioavailability, except for those made from magnesium L-threonate. The 2010 study carried out on Magtein showed that this compound raised the magnesium levels in the brain and neurons effectively.

Magnesium is an important part of our body system and is a cofactor to over 300 enzymes in the body, which help to regulate biochemical reactions in the body. These biochemical reactions include protein synthesis, muscle and nerve actions, blood pressure regulation, and blood glucose regulation. It is safe to say magnesium is an important part of human health[3].

The two main functions of Neuro-Mag are to support healthy memory and cognitive function and to maintain optimal magnesium levels. According to Life Extension’s website, a single bottle of Neuro-Mag contains 90 vegetarian capsules, enough for a one-month supply.

Most of the people who partook in the research on the efficacy of Magtein showed signs of positive improvement in their cognitive abilities and mood from six (6) weeks to twelve (12) weeks with no significant side effects.

The suggested three capsules of Neuro-Mag provide about 2,000 mg of magnesium L-threonate per day, according to Life Extension’s official website.

Some of the other ingredients contained in Neuro-Mag include Vegetable Cellulose (Capsule), Microcrystalline Cellulose, Stearic Acid, Silica, and Vegetable Stearate.

Neuro-Mag Ingredients – Are they Safe & Effective?

The main ingredient in Neuro-Mag is Magtein, aka magnesium L-threonate, which has been significantly researched and tested for efficacy.

Below are some of the other ingredients contained in a Neuro-Mag capsule, including Magtein:

Neuro-Mag Supplement Facts

Neuro-Mag Supplement Facts

Magtein (magnesium L-threonate) 144 mg

Neuro-Mag contains 144mg of magnesium in the form of magtein, a trademarked version of magnesium L-threonate that has been researched and tested for its efficacy on brain function and mood regulation in various studies[4].

In one study, the goal was to determine if supplementation with magnesium L-threonate (Magtein), like Neuro-Mag, can help improve stress/anxiety and fear in healthy adults. The study was performed with adults aged 50 – 70 years with self-reported complaints of stress and anxiety that perpetually impacted quality of life. The subjects were given a dose of approximately 25 mg/kg/day of Magtein, which typically amounts to 1g – 2g per day, depending on the weight of the subject.

The study showed that Magtein significantly helped to improve the perceived stress and anxiety levels of the subjects of the study while also experiencing a significant and clinically meaningful reduction in their fear scores.

Neuro-Mag satisfies the condition for being an effective Magnesium supplement as it delivers up to 2000 mg or 2 g of Magtein (magnesium L-threonate) per day based on the recommended capsule intake of 3 times/day, according to the website.

Older people are more likely to see a significant improvement in cognition due to the intake of Neuro-Mag, according to a study based on Magtein in healthy Chinese adults aged 18 -65 years.

It was stated in an article reviewed by Adrienne Seitz, MS, RD, LDN, a registered dietitian and licensed dietitian nutritionist, that “As magnesium L-threonate can readily elevate magnesium levels in the brain, it has the potential to improve cognitive function.”

Vegetable Cellulose (capsule)

Vegetable cellulose (capsule), also known as vegetarian capsule, has become a mainstay among supplement manufacturers as the go-to capsule for their supplements. Vegetable Cellulose is scientifically known as hydroxypropylmethylcellulose (HPMC), and it is a form of vegetable capsule made from plant fibers[5].

Some of the properties of Vegetable Cellulose, according to a study on vegetarian capsules, that make it highly desirable include:

  • It fulfills all the pharmaceutical dissolution requirements set for United States Pharmacopoeia (USP) and European Pharmacopoeia (EP).
  • It is made from non-animal products, making it suitable for vegetarians.
  • It is stable in a wide range of temperatures and humidity.

Vegetable Cellulose helps to safely store Neuro-Mag before it is absorbed.

An article reviewed by Lizzie Streit, MS, RDN, LD, stated “Cellulose as a food additive is generally recognized as safe (GRAS) by the Food and Drug Administration (FDA). The levels of cellulose currently used in foods are not considered to be dangerous to humans.”

Microcrystalline Cellulose and Silica

Research on silicified microcrystalline cellulose (SMCC) (a combination of silica and microcrystalline cellulose) showed that it has some physio-mechanical properties (any physical property that is affected by mechanical processes. E.g. erosion) that makes it advantageous in hard gelatin capsule formulations.

The point of the study was to measure the performance of SMCC relative to that of other excipients commonly used in hard gelatin capsules. The result showed that SMCC is a good direct-fill excipient for hard shell capsule formulations[6].

This makes Neuro-Mag easier to dissolve and absorb in the body.


The ingredients contained in Neuro-Mag have been scientifically studied and tested for effectiveness. The dosage of magnesium contained in Neuro-Mag is the amount recommended for any positive result to be seen within 6 to 12 weeks.

It is safe to say Neuro-Mag is a potentially effective magnesium supplement that can boost cognitive performance.


Nervogen Pro

*All individuals are unique. Your results can and will vary.

How to Use Neuro-Mag

According to Life Extension’s website, the best way to use Neuro-Mag includes:

  • Taking three (3) capsules daily or as recommended by your healthcare practitioner.

Note: Do not exceed the recommended dose of three (3) capsules per day.

According to the website, Neuro-Mag has a lesser laxative effect than other magnesium supplements.

Neuro-Mag – FAQs

Q: What is Neuro-Mag Good For?

A: Neuro-Mag is a potentially effective magnesium supplement that can boost cognitive performance. Neuro-Mag is essentially a magnesium supplement that is absorbed more easily by the brain due to it deriving its magnesium from Magtein (magnesium l-threonate), a proprietary form of magnesium that has been shown to help improve cognitive functions and improve brain health.

Q: Does Neuro-Mag Help with Sleep?

A: Yes, several reviews on Amazon say that Neuro-Mag has helped significantly with sleep quality.

Q: What is the Use of MG Threonate?

A: Studies have shown that Magtein significantly helped to improve the perceived stress and anxiety levels of the subjects of the study while also experiencing significant and clinically meaningful reductions in their fear scores.
This is the feature that Neuro-Mag relies upon to function properly.

Q: What is Neuro-Mag magnesium?

A: Neuro-Mag is essentially a magnesium supplement that is absorbed more easily by the brain due to it deriving its magnesium from Magtein (magnesium l-threonate), a proprietary form of magnesium that has been shown to help improve cognitive functions and improve brain health.

Q: When should I take Mag Supplements?

A: You should take Neuro-Mag 3 times a day as directed by your physician or the Life Extension website. Every magnesium supplement is different, but research shows that you need at least 2000 mg of magnesium for at least six (6) weeks straight to see any positive result.

Q: Do I take Neuro-Mag at Night?

A: The recommended dosage for Neuro-Mag is three (3) times/day. You should ask your physician for advice on the dosage and timing of NeuraMag’s usage.

Q: Where Can I Buy Neuro-Mag?

A: You can purchase Neuro-Mag on Life Extension’s official website or on the brand’s official page on Amazon.

Q: How Much Neuro-Mag Cost?

A: According to the Life Extension website, here is the price breakdown for Neuro-Mag:

  • A one-time purchase of one 30-capsule pack of Neuro-Mag costs $30.75 on the website but costs about $28.78 on Amazon.
  • If you purchase four (4) packs at once, then you will get them for $27.50 per pack.
  • The last option is what the brand calls AutoShip, which is essentially a subscription service that lets you choose how many packs of Neuro-Mag you want to ship and how often (measured in the number of months between shipping). The price is $27.50 per pack of Neuro-Mag for this option.

What Do the Neuro-Mag Reviews Say?

Here are a few reviews from customers on Amazon that illustrate their experiences with Neuro-Mag:

Correlation isn’t causation, but I think this stuff might really be having an effect…

Health and mood improvements can be subtle, making it hard to attribute them solely to vitamins or supplements. Maybe other factors, like exercise or less drinking, played a role. But one thing is certain: my sleep quality has significantly improved. I sleep deeper, longer, and wake up with clear, vivid dreams. Mornings start earlier and more refreshed, suggesting that whatever is enhancing my brain at night continues when I wake up.
While some mention better cognition and focus, it’s tough to measure. It could be due to the supplement, but it’s also possible it’s influenced by factors like the placebo effect or confirmation bias.
While I can’t say the supplement directly improved my mood, it coincided with a positive shift. Regardless, improved sleep has boosted my energy and mood, and the vivid dreams are like a nightly show. It might be worth trying for yourself. –Dan Holzner

Oh so sweet!

Initially, I mixed this with coconut water, but it was too sweet, giving me a “pucker face” reaction. However, I persevered by diluting it with plain water, drinking it quickly. I recommend using room temperature water for easier silica dissolution. I recently ordered the pill form because the powdered version was too sweet for my taste.
I used to suffer from nightly leg cramps that kept me awake. After the first night using this product, the cramps became less painful. By the fourth night, they disappeared entirely. I experienced deep, uninterrupted sleep, unlike anything I’ve had in years. I felt incredibly refreshed and calm upon waking, even sleeping through the night without needing to visit the bathroom. I took the powder about 2-3 hours before bedtime with room temperature water, avoiding food in the hours leading up to sleep.
The results amazed me, but I prefer the pill form due to the sweetness of the powder. It’s worth considering the pill option, especially if you’re diabetic or fasting. I’m grateful to have found this effective product from a reputable company I’ve had success with before. –Madeline d

Re-ordering now

I’ve been using this supplement for a month and will continue into the second month. In late October, I’ll undergo blood testing to assess its impact on my magnesium levels.
Initially, my primary care physician suggested Magnesium Oxide, but after conducting my research, I concluded that the synthetic, poorly absorbable oxide product isn’t suitable. Instead, I opt for natural magnesium options that the body can readily absorb and utilize. This L-Threonate supplement is one of my choices, and I also incorporate Glycinate into my regimen. –Nathan Harr

Neuro-Mag Reviews – Conclusion

In summary, Neuro-Mag, a magnesium supplement by Life Extension, stands as a potential asset for those seeking to bolster cognitive performance and support overall brain health. It has a general rating of 3.7, which is considered high for a supplement brand.

Life Extension, the reputable manufacturer behind Neuro-Mag, has a longstanding presence in the supplements industry and is known for its commitment to research and product quality. The primary ingredient, Magtein (magnesium l-threonate), is backed by scientific studies demonstrating its efficacy in enhancing cognitive function and mood regulation.

In conclusion, Neuro-Mag by Life Extension offers a compelling choice for those interested in enhancing cognitive performance and safeguarding brain health. Its effectiveness, coupled with the reputable brand behind it, positions it as a promising supplement.

However, as with any dietary addition, consulting with a healthcare professional is advisable, particularly if you have underlying health concerns or sensitivities.
Remember, your well-being remains paramount.

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Claritox Pro | Vertigo Support Supplement
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Nootrogen | Nutritional Nootropic Brain Support
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Noocube | Premium Brain Productivity Supplement
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Zenith Labs Brain C-13 | Advanced Brain Health Support
Promotes Memory*Gold Star Evidence
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Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Neuro-Mag

Neuro-Mag Review: Does It Really Work as Advertised?

Customer Reviews & Ratings

3.0 out of 5

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  1. Juanita

    Worked for me!!!
    I’ve been using Neuro-Mag for a few weeks now, and I can already feel the difference in my focus and memory. I love that it contains magnesium, a mineral essential for brain function. I’ve tried other supplements, but Neuro-Mag stands out because of its high-quality ingredients and noticeable effects. I highly recommend it to anyone looking to support their brain health and overall cognitive function!

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Life Extension
90 Capsules
Magnesium, Vegetable Cellulose, Microcrystalline Cellulose, Stearic Acid, Silica, and others.

6 sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Magnesium and the Brain: A Focus on Neuroinflammation and Neurodegeneration:
[2] A Magtein®, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults:
[3] Magnesium:
[4] A Randomized, Double-Blind, Placebo-Controlled, Comparator Trial Evaluating Magtein® Magnesium Supplement on Quality of Life as Related to Levels of Stress, Anxiety, Fear and Other Indicators.:
[6] Potential application of silicified microcrystalline cellulose in direct-fill formulations for automatic capsule-filling machines:

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

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