In This Review
Systeme41 Overview
It is an advanced skincare formula that prevents the appearance of wrinkles and fine lines on the skin of the face as it ages with time.

Systeme41
This cream utilizes plant stem cell technology in addition to natural ingredients to promote young and naturally glowing skin.
Who Manufactures Systeme41
The Systeme 41 company makes and manufactures their special neck treatment cream and many other skincare products with their 80 years of experience in developing cosmetic products for doctors, salons, and leading skincare brands.
This USA-based company is led by Dr. Janet Zand, a board-certified acupuncturist, a Doctor of Oriental Medicine, and Dr. David Wood, a research chemist, and scientist. There is a dedicated team of scientists to develop all-natural skincare products that can help to fight against the aging of the skin and generate new cells.
Headquarters: PO Box 8051, Norcross, Georgia, 30093, United States
Phone Number: (800) 791-3446
How Does Systeme41 Works?
This cream works by removing common manifestations of aging on the skin, for instance, dark spots, fine lines, and wrinkles.
In order to do this, the ingredients in the formula improve the production of collagen in the skin, which consequently improves the skin’s elastic nature.
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*All individuals are unique. Your results can and will vary.
It also has ingredients that have been clinically proven to reduce skin inflammations.
The cream also improves the skin’s immunity thus protecting it from free radicals in the atmosphere; it covers the skin with a protective layer that blocks harmful UV rays from the sun.
Systeme41 Ingredients
Sweet almond oil – this ingredient is rich in vitamins E, A, and B vitamins that are effective in promoting well-hydrated skin.
Rosehip oil – According to the study, it is rich in linolenic fatty acids that improves the skin’s elasticity. It also repairs the skin cells.
Sunflower seed oil – contains antioxidants and vitamin E that protect the skin against damage caused by free radicals in the atmosphere.
Bilberry fruit extract – According to Science Direct, it protects the skin against inflammation and also has antibacterial attributes.
Phospholipids – retains the skin’s moisture thus keeping it well hydrated.
White Tea leaf extract – has oxidants that help fight wrinkles.
Red Algae extract – According to Research Gate, it acts as a powerful antioxidant that improves elastin skin tissues and reduces wrinkles. It also nourishes and rejuvenates the skin cells.
Shea Butter – improves collagen synthesis.
Kuikui seed oil – contains omega-3 fatty acids that fight against UV rays.
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*All individuals are unique. Your results can and will vary.
Systeme41 Pros
- This formula does not contain harsh chemicals and fillers that are harmful to the skin.
- It fights wrinkles on the skin and thus promotes a youthful appearance.
- This formula keeps the skin supple and moisturized by making it well hydrated.
- It repairs damaged skin cells.
- This formula promotes radiant and naturally glowing skin.
- It increases the level of collagen in the skin.
- This formula also protects against damage caused by prolonged exposure to the sun.
System41 Cons
- Results are not uniform and as a result, consumers may not always achieve the same results.
- It is not recommended for those below the age of 30.
- Prolonged use can lead to skin irritation.
- Little information is offered on the product’s money-back guarantee policy.
Systeme41 Alternatives
Systeme41 Questions and Answers
Q: Where Can You Buy Systeme41?
A: You can Buy it from their Official Website.
Q: What are the Application instructions of Systeme41?
A: Application of this cream is very easy. It involves removing all forms of makeup on your skin prior to its application, washing the face clean, and then drying it up with a damp towel.
Then apply the cream to the face taking caution not to put it into the eyes. Allow the cream to be absorbed into your skin.
Consistent use of this cream will guarantee improved skin tone and texture even for those with dry and flaky skin.
Q: What are the Side Effects of Systeme41?
A: Despite the large list of ingredients the formula possesses, none of them pose any type of threat to the skin.
Therefore, it is safe to use and guarantees reliable results within a short time. A lot of customers have provided positive reviews on the cream’s effectiveness.
System41 Review – Final Verdict
Systeme41 skin serum fights wrinkles and improves facial appearance. It has been formulated by a team of professional dermatologists and follows the cream’s more than eight decades of research in the field of skincare; this backs up its abilities and attributes as far as skincare is concerned.
However, it is important to note that prolonged and inconsistent use of this cream can lead to skin irritation, burning sensations, and scarring in some instances; care should be taken when using it.
‘Systeme41’ can be purchased through their Official WebSite.
As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.
Below you’ll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.
Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned anti-aging products and anti-wrinkle creams based on the available research:

Debra K.
Melanie J Heinonen
MARLENE GLASSER LANER